Cynthia X Ma

Cynthia X Ma

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Cynthia X Ma

Cynthia X Ma

Publications by authors named "Cynthia X Ma"

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PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer.

Oncotarget 2019 Jun 4;10(38):3667-3680. Epub 2019 Jun 4.

Section of Medical Oncology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557212PMC
June 2019

Neutrophil-to-lymphocyte ratio as a predictor of survival in patients with triple-negative breast cancer.

Breast Cancer Res Treat 2019 Apr 2;174(2):443-452. Epub 2019 Jan 2.

Washington University School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s10549-018-05106-7DOI Listing
April 2019

Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER breast cancer.

FASEB J 2019 02 30;33(2):1644-1657. Epub 2018 Aug 30.

Department of Molecular and Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.

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https://www.fasebj.org/doi/10.1096/fj.201801241R
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http://dx.doi.org/10.1096/fj.201801241RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338642PMC
February 2019

Male Breast Cancer: An Updated Surveillance, Epidemiology, and End Results Data Analysis.

Clin Breast Cancer 2018 10 27;18(5):e997-e1002. Epub 2018 Jun 27.

Washington University Brown School of Public Health, St. Louis, MO; Section of Medical Oncology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2018.06.013DOI Listing
October 2018

Breast cancer stage variation and survival in association with insurance status and sociodemographic factors in US women 18 to 64 years old.

Cancer 2017 Aug 25;123(16):3125-3131. Epub 2017 Apr 25.

Brown School, Washington University in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1002/cncr.30722DOI Listing
August 2017

The role of neratinib in HER2-driven breast cancer.

Future Oncol 2017 Jun 30. Epub 2017 Jun 30.

Division of Oncology, Department of Medicine, Washington University in Saint Louis, St Louis, MO 63110, USA.

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http://dx.doi.org/10.2217/fon-2017-0186DOI Listing
June 2017

Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).

J Clin Oncol 2017 Apr 3;35(10):1061-1069. Epub 2017 Jan 3.

Matthew J. Ellis and Chad J. Creighton, Baylor College of Medicine; Gildy Babiera and Kelly Hunt, MD Anderson Cancer Center, Houston; Gary Unzeitig, Doctor's Hospital of Laredo, Laredo; Marilyn Leitch, University of Texas Southwestern Campus, Dallas, TX; Vera J. Suman, Mayo Clinic, Rochester MN; Jeremy Hoog, Rodrigo Goncalves, Souzan Sanati, Katherine DeSchryver, Erika Crouch, Amy Brink, Mark Watson, Jingqin Luo, Yu Tao, Cynthia X. Ma, and D. Craig Allred, Washington University School of Medicine, St Louis; Timothy Pluard, St Lukes Hospital, Kansas City, MO; Michael Barnes, Roche Diagnostics, Mountain View; Laura Esserman, University of California San Francisco, San Francisco, CA; Mitchell Dowsett, Royal Marsden Hospital, London, UK; G. Thomas Budd, Cleveland Clinic; Paula Silverman, Case Western Reserve University, Cleveland OH; Eric Winer, Dana-Farber Cancer Institute, Boston MA; Lisa Carey, University of North Carolina, Chapel Hill; David Ota, Duke University, Durham, NC; Pat Whitworth, Nashville Breast Center, Nashville, TN; J. Michael Guenther, St Elizabeth Medical Center, Edgewood, KY; Zoneddy Dayao, University of New Mexico, Albuquerque, NM; and John A. Olson Jr, University of Maryland School of Medicine and Greenebaum Cancer Center, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2016.69.4406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455353PMC
April 2017

Differences in the mutational landscape of triple-negative breast cancer in African Americans and Caucasians.

Breast Cancer Res Treat 2017 02 3;161(3):491-499. Epub 2016 Dec 3.

Division of Oncology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s10549-016-4062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243212PMC
February 2017

Prognostic and Predictive Biomarkers of Endocrine Responsiveness for Estrogen Receptor Positive Breast Cancer.

Adv Exp Med Biol 2016 ;882:125-54

Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, 320A Cullen, MS 600, 77030, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-3-319-22909-6_5DOI Listing
August 2016

Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer.

Oncotarget 2016 Aug;7(35):56864-56875

Section of Medical Oncology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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http://www.oncotarget.com/fulltext/10870
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http://dx.doi.org/10.18632/oncotarget.10870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302958PMC
August 2016

Chemotherapy principles of managing stage IV breast cancer in the United States.

Chin Clin Oncol 2016 Jun 14;5(3):42. Epub 2016 Apr 14.

Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, USA. Email:

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http://dx.doi.org/10.21037/cco.2016.04.01DOI Listing
June 2016

HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor.

J Natl Compr Canc Netw 2015 Sep;13(9):1061-4

From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas. From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas. From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas.

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http://www.jnccn.org/content/13/9/1061.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701428PMC
http://dx.doi.org/10.6004/jnccn.2015.0131DOI Listing
September 2015

Cognitive impairment after chemotherapy related to atypical network architecture for executive control.

Oncology 2015 7;88(6):360-8. Epub 2015 Feb 7.

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, Mo., USA.

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http://dx.doi.org/10.1159/000370117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449788PMC
August 2015

US breast cancer mortality trends in young women according to race.

Cancer 2015 May 5;121(9):1469-76. Epub 2014 Dec 5.

Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1002/cncr.29178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409464PMC
May 2015

Mechanisms of aromatase inhibitor resistance.

Nat Rev Cancer 2015 May;15(5):261-75

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston 77030, Texas, USA.

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http://dx.doi.org/10.1038/nrc3920DOI Listing
May 2015

Treatment-associated musculoskeletal and vasomotor symptoms and relapse-free survival in the NCIC CTG MA.27 adjuvant breast cancer aromatase inhibitor trial.

J Clin Oncol 2015 Jan 15;33(3):265-71. Epub 2014 Dec 15.

Vered Stearns, Kimmel Cancer Center, Johns Hopkins, Baltimore, MD; Judith-Anne W. Chapman, Aurélie Le Maitre, Jessica Kundapur, and Lois E. Shepherd, NCIC Clinical Trials Group, Queen's University, Kingston; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre and University of Toronto, Toronto, Ontario, Canada; Cynthia X. Ma, Siteman Cancer Center, Washington University, St Louis, MO; Matthew J. Ellis, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX; James N. Ingle, Mayo Clinic, Rochester, MN; G. Thomas Budd, Cleveland Clinic, Cleveland, OH; George W. Sledge, Stanford University, San Francisco, CA; Pedro E.R. Liedke and Paul E. Goss, Harvard University; Paul E. Goss, Avon International Breast Cancer Research Program, Massachusetts General Hospital, Boston, MA; Manuela Rabaglio, Inselspital University Hospital and International Breast Cancer Study Group Coordinating Center, Berne, Switzerland; and Pedro E.R. Liedke, Hospital de Clínicas de Porto Alegre and Instituto do Cancer Mãe de Deus, Oncologia, Porto Alegre, Rio Grande do Sul, Brazil.

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http://jco.ascopubs.org/content/33/3/265.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.57.6926
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http://dx.doi.org/10.1200/JCO.2014.57.6926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289722PMC
January 2015

Body mass index, diabetes, and triple-negative breast cancer prognosis.

Breast Cancer Res Treat 2014 Jul 29;146(1):189-97. Epub 2014 May 29.

Department of Biology, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1007/s10549-014-3002-yDOI Listing
July 2014

Incorporating genomics into breast cancer clinical trials and care.

Clin Cancer Res 2013 Dec;19(23):6371-9

Authors' Affiliation: Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0837DOI Listing
December 2013

The Cancer Genome Atlas: clinical applications for breast cancer.

Oncology (Williston Park) 2013 Dec;27(12):1263-9, 1274-9

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December 2013

Targeted therapy for breast cancer.

Am J Pathol 2013 Oct 27;183(4):1096-1112. Epub 2013 Aug 27.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.07.005DOI Listing
October 2013

Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models.

Mol Cancer Ther 2013 Aug 20;12(8):1665-75. Epub 2013 May 20.

Section of Breast Oncology, Division of Oncology, Department of Internal Medicine, Washington University in St Louis, School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742690PMC
August 2013

Neoadjuvant therapy in operable breast cancer: application to triple negative breast cancer.

J Oncol 2013 1;2013:219869. Epub 2013 Aug 1.

Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1155/2013/219869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747378PMC
August 2013

A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.

Breast Cancer Res Treat 2013 May 19;139(1):145-53. Epub 2013 Apr 19.

Section of Breast Oncology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Avenue, P.O. Box 8056, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s10549-013-2528-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517667PMC
May 2013

Adjuvant chemotherapy decisions in clinical practice for early-stage node-negative, estrogen receptor-positive, HER2-negative breast cancer: challenges and considerations.

J Natl Compr Canc Netw 2013 Mar;11(3):246-50; quiz 251

Division of Medical Oncology and Hematology, Loma Linda University, Loma Linda, California 92354, USA.

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http://dx.doi.org/10.6004/jnccn.2013.0036DOI Listing
March 2013

Activating HER2 mutations in HER2 gene amplification negative breast cancer.

Cancer Discov 2013 Feb 7;3(2):224-37. Epub 2012 Dec 7.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570596PMC
February 2013

Racial differences in outcomes of triple-negative breast cancer.

Breast Cancer Res Treat 2013 Feb 12;138(1):281-9. Epub 2013 Feb 12.

Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1007/s10549-012-2397-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537526PMC
February 2013

Phase II trial of temsirolimus in patients with metastatic breast cancer.

Breast Cancer Res Treat 2012 Nov 13;136(2):355-63. Epub 2012 Jan 13.

The University of Chicago Medical Center, 5841 South Maryland Ave., MC 2115, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s10549-011-1910-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658119PMC
November 2012

The natural history of hormone receptor-positive breast cancer: attempting to decipher an intriguing concept.

Oncology (Williston Park) 2012 Aug;26(8):696-7, 700

Department of Medicine, Division of Hematology , Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

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August 2012

Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models.

J Clin Invest 2012 Apr 26;122(4):1541-52. Epub 2012 Mar 26.

Section of Breast Oncology, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110-1093, USA.

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http://dx.doi.org/10.1172/JCI58765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314455PMC
April 2012

Endocrine resistance in breast cancer: molecular pathways and rational development of targeted therapies.

Future Oncol 2012 Mar;8(3):273-92

Washington University School of Medicine in Saint Louis, Department of Medicine, Divisions of Hematology & Oncology, St Louis, MO, USA.

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http://dx.doi.org/10.2217/fon.12.8DOI Listing
March 2012

Molecular profiling of triple negative breast cancer.

Breast Dis 2010 ;32(1-2):73-84

Section of Breast Oncology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.3233/BD-2010-0309DOI Listing
February 2012

PARP inhibitors and their evolving role in breast cancer.

Oncology (Williston Park) 2011 Oct;25(11):1033-4

Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.

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October 2011

Importance of PI3-kinase pathway in response/resistance to aromatase inhibitors.

Steroids 2011 Jul 21;76(8):750-2. Epub 2011 Mar 21.

Siteman Comprehensive Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.steroids.2011.02.023DOI Listing
July 2011

Estrogen and progesterone receptors in breast cancer.

Authors:
Cynthia X Ma

Clin Adv Hematol Oncol 2011 May;9(5):385-6

Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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May 2011

Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer.

Breast Cancer Res 2011 Mar 1;13(2):R21. Epub 2011 Mar 1.

Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Catolica de Chile, Lira 85, 4th floor, Santiago 8330023, Chile.

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http://dx.doi.org/10.1186/bcr2833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219179PMC
March 2011

Death by releasing the breaks: CHK1 inhibitors as cancer therapeutics.

Trends Mol Med 2011 Feb 17;17(2):88-96. Epub 2010 Nov 17.

Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.molmed.2010.10.009DOI Listing
February 2011

Neoadjuvant endocrine therapy for breast cancer.

Surg Oncol Clin N Am 2010 Jul;19(3):627-38

Division of Oncology, Department of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.soc.2010.04.004DOI Listing
July 2010

Predicting endocrine therapy responsiveness in breast cancer.

Oncology (Williston Park) 2009 Feb;23(2):133-42

Section of Medical Oncology, Division of Oncology, Department of Internal Medicine, Siteman Comprehensive Cancer Center, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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February 2009

A comprehensive examination of CYP19 variation and breast density.

Cancer Epidemiol Biomarkers Prev 2007 Mar;16(3):623-5

Division of Epidemiology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55901, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0781DOI Listing
March 2007

Neoadjuvant endocrine therapy for locally advanced breast cancer.

Semin Oncol 2006 Dec;33(6):650-6

Department of Oncology, Siteman Comprehensive Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009377540600324
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http://dx.doi.org/10.1053/j.seminoncol.2006.08.013DOI Listing
December 2006

Human aromatase: gene resequencing and functional genomics.

Cancer Res 2005 Dec;65(23):11071-82

Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1218DOI Listing
December 2005

Acquired Fanconi syndrome is an indolent disorder in the absence of overt multiple myeloma.

Blood 2004 Jul 9;104(1):40-2. Epub 2004 Mar 9.

Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1182/blood-2003-10-3400DOI Listing
July 2004

Imatinib mesylate-induced interstitial pneumonitis.

Mayo Clin Proc 2003 Dec;78(12):1578-9

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http://dx.doi.org/10.4065/78.12.1578DOI Listing
December 2003