Cynthia C Bartholomae

Cynthia C Bartholomae

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Cynthia C Bartholomae

Cynthia C Bartholomae

Publications by authors named "Cynthia C Bartholomae"

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30Publications

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The LAM-PCR Method to Sequence LV Integration Sites.

Methods Mol Biol 2016 ;1448:107-20

Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3753-0_9DOI Listing
January 2018

Impact of raltegravir on HIV-1 RNA and DNA forms following initiation of antiretroviral therapy in treatment-naive patients.

J Antimicrob Chemother 2014 Oct 23;69(10):2809-18. Epub 2014 Jun 23.

Institute of Medical Virology, National Reference Center for Retroviruses, University Hospital Frankfurt, Frankfurt, Germany Department of Infectious Diseases, Virology, University of Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.1093/jac/dku213DOI Listing
October 2014

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.

Nature 2014 Jul 22;511(7510):428-34. Epub 2014 Jun 22.

1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany [2] Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg 69120, Germany.

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http://www.abta.org/resources/enhancers-hijacking-activates.
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http://www.nature.com/doifinder/10.1038/nature13379
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http://dx.doi.org/10.1038/nature13379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201514PMC
July 2014

Linear amplification mediated PCR--localization of genetic elements and characterization of unknown flanking DNA.

J Vis Exp 2014 Jun 25(88):e51543. Epub 2014 Jun 25.

Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ);

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http://dx.doi.org/10.3791/51543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205898PMC
June 2014

Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in Hemophilia B mice.

Mol Ther 2014 Mar 14;22(3):567-574. Epub 2013 Aug 14.

Gene Therapy Center, University of North Carolina, Chapel Hill, North Carolina, USA; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2013.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944325PMC
March 2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Cancer Cell 2014 Mar;25(3):393-405

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69121 Heidelberg, Germany; Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2014.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493053PMC
March 2014

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Nat Genet 2013 Aug 30;45(8):927-32. Epub 2013 Jun 30.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:1982973/compon
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http://www.nature.com/doifinder/10.1038/ng.2682
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http://dx.doi.org/10.1038/ng.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951336PMC
August 2013

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

Insertion site pattern: global approach by linear amplification-mediated PCR and mass sequencing.

Methods Mol Biol 2012 ;859:255-65

Department of Translational Oncology, National Center of Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-61779-603-6_15DOI Listing
June 2012

Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.

Hum Gene Ther Methods 2012 Apr 4;23(2):111-8. Epub 2012 May 4.

Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1089/hgtb.2011.219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015219PMC
April 2012

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing.

Nat Protoc 2010 Aug 8;5(8):1379-95. Epub 2010 Jul 8.

Department of Translational Oncology, National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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http://www.nature.com/articles/nprot.2010.87
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http://dx.doi.org/10.1038/nprot.2010.87DOI Listing
August 2010

Detection of retroviral integration sites by linear amplification-mediated PCR and tracking of individual integration clones in different samples.

Methods Mol Biol 2009 ;506:363-72

Department of Translational Oncology, National Center of Tumor Diseases, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-59745-409-4_24DOI Listing
February 2009