Curtis S Younkin

Curtis S Younkin

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Curtis S Younkin

Curtis S Younkin

Publications by authors named "Curtis S Younkin"

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Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy.

Authors:
Mariet Allen Xue Wang Daniel J Serie Samantha L Strickland Jeremy D Burgess Shunsuke Koga Curtis S Younkin Thuy T Nguyen Kimberly G Malphrus Sarah J Lincoln Melissa Alamprese Kuixi Zhu Rui Chang Minerva M Carrasquillo Naomi Kouri Melissa E Murray Joseph S Reddy Cory Funk Nathan D Price Todd E Golde Steven G Younkin Yan W Asmann Julia E Crook Dennis W Dickson Nilüfer Ertekin-Taner

Acta Neuropathol 2018 11 22;136(5):709-727. Epub 2018 Aug 22.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1007/s00401-018-1900-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208732PMC
November 2018

ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans.

Authors:
Olivia J Conway Minerva M Carrasquillo Xue Wang Jenny M Bredenberg Joseph S Reddy Samantha L Strickland Curtis S Younkin Jeremy D Burgess Mariet Allen Sarah J Lincoln Thuy Nguyen Kimberly G Malphrus Alexandra I Soto Ronald L Walton Bradley F Boeve Ronald C Petersen John A Lucas Tanis J Ferman William P Cheshire Jay A van Gerpen Ryan J Uitti Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford Nilüfer Ertekin-Taner

Mol Neurodegener 2018 10 11;13(1):53. Epub 2018 Oct 11.

Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1186/s13024-018-0289-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190665PMC
October 2018

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.

Authors:
Mariet Allen Xue Wang Jeremy D Burgess Jens Watzlawik Daniel J Serie Curtis S Younkin Thuy Nguyen Kimberly G Malphrus Sarah Lincoln Minerva M Carrasquillo Charlotte Ho Paramita Chakrabarty Samantha Strickland Melissa E Murray Vivek Swarup Daniel H Geschwind Nicholas T Seyfried Eric B Dammer James J Lah Allan I Levey Todd E Golde Cory Funk Hongdong Li Nathan D Price Ronald C Petersen Neill R Graff-Radford Steven G Younkin Dennis W Dickson Julia R Crook Yan W Asmann Nilüfer Ertekin-Taner

Alzheimers Dement 2018 03 31;14(3):352-366. Epub 2017 Oct 31.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866744PMC
March 2018

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.

Authors:
Minerva M Carrasquillo Mariet Allen Jeremy D Burgess Xue Wang Samantha L Strickland Shivani Aryal Joanna Siuda Michaela L Kachadoorian Christopher Medway Curtis S Younkin Asha Nair Chen Wang Pritha Chanana Daniel Serie Thuy Nguyen Sarah Lincoln Kimberly G Malphrus Kevin Morgan Todd E Golde Nathan D Price Charles C White Philip L De Jager David A Bennett Yan W Asmann Julia E Crook Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner

Alzheimers Dement 2017 Jun 8;13(6):663-673. Epub 2016 Dec 8.

Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, USA; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462884PMC
June 2017

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.

Authors:
Mariet Allen Minerva M Carrasquillo Cory Funk Benjamin D Heavner Fanggeng Zou Curtis S Younkin Jeremy D Burgess High-Seng Chai Julia Crook James A Eddy Hongdong Li Ben Logsdon Mette A Peters Kristen K Dang Xue Wang Daniel Serie Chen Wang Thuy Nguyen Sarah Lincoln Kimberly Malphrus Gina Bisceglio Ma Li Todd E Golde Lara M Mangravite Yan Asmann Nathan D Price Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner

Sci Data 2016 Oct 11;3:160089. Epub 2016 Oct 11.

Mayo Clinic, Department of Neuroscience, 4500 San Pablo Road, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1038/sdata.2016.89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058336PMC
October 2016

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.

Authors:
Mariet Allen Jeremy D Burgess Travis Ballard Daniel Serie Xue Wang Curtis S Younkin Zhifu Sun Naomi Kouri Saurabh Baheti Chen Wang Minerva M Carrasquillo Thuy Nguyen Sarah Lincoln Kimberly Malphrus Melissa Murray Todd E Golde Nathan D Price Steven G Younkin Gerard D Schellenberg Yan Asmann Tamas Ordog Julia Crook Dennis Dickson Nilüfer Ertekin-Taner

Acta Neuropathol 2016 08 26;132(2):197-211. Epub 2016 Apr 26.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1007/s00401-016-1576-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947429PMC
August 2016

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.

Authors:
Naomi Kouri Owen A Ross Beth Dombroski Curtis S Younkin Daniel J Serie Alexandra Soto-Ortolaza Matthew Baker Ni Cole A Finch Hyejin Yoon Jungsu Kim Shinsuke Fujioka Catriona A McLean Bernardino Ghetti Salvatore Spina Laura B Cantwell Martin R Farlow Jordan Grafman Edward D Huey Mi Ryung Han Sherry Beecher Evan T Geller Hans A Kretzschmar Sigrun Roeber Marla Gearing Jorge L Juncos Jean Paul G Vonsattel Vivianna M Van Deerlin Murray Grossman Howard I Hurtig Rachel G Gross Steven E Arnold John Q Trojanowski Virginia M Lee Gregor K Wenning Charles L White Günter U Höglinger Ulrich Müller Bernie Devlin Lawrence I Golbe Julia Crook Joseph E Parisi Bradley F Boeve Keith A Josephs Zbigniew K Wszolek Ryan J Uitti Neill R Graff-Radford Irene Litvan Steven G Younkin Li-San Wang Nilüfer Ertekin-Taner Rosa Rademakers Hakon Hakonarsen Gerard D Schellenberg Dennis W Dickson

Nat Commun 2015 Jun 16;6:7247. Epub 2015 Jun 16.

Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1038/ncomms8247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469997PMC
June 2015

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.

Authors:
Fanggeng Zou High Seng Chai Curtis S Younkin Mariet Allen Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Naomi Kouri Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner

PLoS Genet 2012 7;8(6):e1002707. Epub 2012 Jun 7.

Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.

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https://ncrad.iu.edu/docs/Publications/155_Zou_2012.pdf
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http://dx.plos.org/10.1371/journal.pgen.1002707
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369937PMC
http://dx.doi.org/10.1371/journal.pgen.1002707DOI Listing
September 2012

Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations.

Authors:
Krishna R Kalari David Rossell Brian M Necela Yan W Asmann Asha Nair Saurabh Baheti Jennifer M Kachergus Curtis S Younkin Tiffany Baker Jennifer M Carr Xiaojia Tang Michael P Walsh High-Seng Chai Zhifu Sun Steven N Hart Alexey A Leontovich Asif Hossain Jean-Pierre Kocher Edith A Perez David N Reisman Alan P Fields E Aubrey Thompson

Front Oncol 2012 10;2:12. Epub 2012 Feb 10.

Division of Biostatistics and Bioinformatics, Department of Health Sciences Research, Mayo Clinic Rochester, MN, USA.

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http://dx.doi.org/10.3389/fonc.2012.00012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356053PMC
August 2012

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Richard Miles Asha A Nair Julia E Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Thuy Nguyen Li Ma Kimberly G Malphrus Gina Bisceglio Alexandra I Ortolaza Ryan Palusak Sumit Middha Sooraj Maharjan Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Sigrid B Sando Jan O Aasly Maria Barcikowska Ryan J Uitti Zbigniew K Wszolek Owen A Ross Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner

Mol Neurodegener 2012 Apr 11;7:13. Epub 2012 Apr 11.

Mayo Clinic Florida, Department of Neuroscience, Jacksonville, FL, USA.

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http://dx.doi.org/10.1186/1750-1326-7-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393625PMC
April 2012

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.

Authors:
Minerva M Carrasquillo Olivia Belbin Fanggeng Zou Mariet Allen Nilufer Ertekin-Taner Morad Ansari Samantha L Wilcox Mariah R Kashino Li Ma Linda H Younkin Samuel G Younkin Curtis S Younkin Toros A Dincman Melissa E Howard Chanley C Howell Chloe M Stanton Christopher M Watson Michael Crump Veronique Vitart Caroline Hayward Nicholas D Hastie Igor Rudan Harry Campbell Ozren Polasek Kristelle Brown Peter Passmore David Craig Bernadette McGuinness Stephen Todd Patrick G Kehoe David M Mann A David Smith Helen Beaumont Donald Warden Clive Holmes Reinhard Heun Heike Kölsch Noor Kalsheker V Shane Pankratz Dennis W Dickson Neill R Graff-Radford Ronald C Petersen Alan F Wright Steven G Younkin Kevin Morgan

PLoS One 2010 Jan 19;5(1):e8764. Epub 2010 Jan 19.

Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008764PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808243PMC
January 2010

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.

Authors:
Minerva M Carrasquillo Fanggeng Zou V Shane Pankratz Samantha L Wilcox Li Ma Louise P Walker Samuel G Younkin Curtis S Younkin Linda H Younkin Gina D Bisceglio Nilufer Ertekin-Taner Julia E Crook Dennis W Dickson Ronald C Petersen Neill R Graff-Radford Steven G Younkin

Nat Genet 2009 Feb 11;41(2):192-8. Epub 2009 Jan 11.

Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1038/ng.305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873177PMC
February 2009