Cristina Romei

Cristina Romei

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Cristina Romei

Cristina Romei

Publications by authors named "Cristina Romei"

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68Publications

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Analysis of circulating tumor DNA does not improve the clinical management of patients with locally advanced and metastatic papillary thyroid carcinoma.

Head Neck 2018 Aug 22;40(8):1752-1758. Epub 2018 Mar 22.

Department of Surgical, Medical, Molecular Pathology and Critical Area, University Hospital of Pisa, Pisa, Italy.

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August 2018

RET mutation heterogeneity in primary advanced medullary thyroid cancers and their metastases.

Oncotarget 2018 Feb 4;9(11):9875-9884. Epub 2018 Jan 4.

Endocrine Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa, Italy.

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February 2018

Clinical impact of molecular techniques for the presurgical diagnosis of differentiated thyroid cancer diagnosis.

Expert Rev Endocrinol Metab 2017 May 24;12(3):207-214. Epub 2017 Apr 24.

a Endocrine Unit, Department of Clinical and Experimental Medicine , University of Pisa , Pisa , Italy.

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May 2017

Inherited variants in genes somatically mutated in thyroid cancer.

PLoS One 2017 14;12(4):e0174995. Epub 2017 Apr 14.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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April 2017

Corrigendum to "Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission" [Brain Res. Bull. 127 (2016) 100-110].

Brain Res Bull 2017 01;128:113

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy. Electronic address:

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January 2017

Papillary Thyroid Carcinoma With Rare Exon 15 BRAF Mutation Has Indolent Behavior: A Single-Institution Experience.

J Clin Endocrinol Metab 2016 11 29;101(11):4413-4420. Epub 2016 Aug 29.

Unit of Surgical Pathology (L.T., E.S., M.G., F.B.), Department of Surgical, Medical, and Molecular Pathology and Critical Care Medicine; Endocrine Section (D.V., P.P., C.R., R.E.), Department of Clinical and Experimental Medicine, World Health Organization Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders; and Endocrine Surgery Unit (G.M., P.M.), Department of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.

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November 2016

Advances in understanding the functions of native GlyT1 and GlyT2 neuronal glycine transporters.

Neurochem Int 2016 10 6;99:169-177. Epub 2016 Jul 6.

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy. Electronic address:

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October 2016

Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission.

Brain Res Bull 2016 10 24;127:100-110. Epub 2016 Aug 24.

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy. Electronic address:

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October 2016

A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma.

Nat Rev Endocrinol 2016 Apr 12;12(4):192-202. Epub 2016 Feb 12.

Endocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.

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April 2016

Runs of homozygosity and inbreeding in thyroid cancer.

BMC Cancer 2016 Mar 16;16:227. Epub 2016 Mar 16.

Molecular Genetic Epidemiology, C050, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.

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March 2016

Elevated level of serum carbohydrate antigen 19.9 as predictor of mortality in patients with advanced medullary thyroid cancer.

Eur J Endocrinol 2015 Sep 1;173(3):297-304. Epub 2015 Jun 1.

Endocrine UnitDepartment of Clinical and Experimental MedicineDepartment of SurgicalMedical, Molecular Pathology, University of Pisa, Pisa, Italy andClinical Chemistry LaboratoryAzienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

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September 2015

Medullary thyroid carcinoma in children.

Endocr Dev 2014 29;26:202-13. Epub 2014 Aug 29.

Endocrinology Unit, Department of Clinical and Experimental Medicine, WHO Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders, University of Pisa, Pisa, Italy.

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May 2015

Novel genetic variants in differentiated thyroid cancer and assessment of the cumulative risk.

Sci Rep 2015 Mar 10;5:8922. Epub 2015 Mar 10.

1] Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany [2] Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.

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March 2015

High-affinity GABA uptake by neuronal GAT1 transporters provokes release of [(3)H]GABA by homoexchange and through GAT1-independent Ca(2+)-mediated mechanisms.

Neuropharmacology 2015 Jan 20;88:164-70. Epub 2014 Aug 20.

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy; National Institute of Neuroscience, Genoa, Italy. Electronic address:

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January 2015

Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk.

J Clin Endocrinol Metab 2014 Oct 16;99(10):E2084-92. Epub 2014 Jul 16.

Department of Biology (G.F., M.C., E.P., S.L., F.G.), University of Pisa, 56123 Pisa, Italy; Molecular Genetic Epidemiology (A.K., B.C., K.H., A.F.), German Cancer Research Center, 69120 Heidelberg, Germany; Department of Endocrinology and Metabolism (R.E., C.R., A.C.), University of Pisa, 56124 Pisa, Italy; Blood Centre (F.B.), Azienda Ospedaliero Universitaria A. Meyer, 50139 Firenze, Italy; Department of Genomics (P.H., S.H.), Life and Brain Center and Institute of Human Genetics (P.H., S.H.), University of Bonn, D-53127 Bonn, Germany; Division of Medical Genetics (P.H., S.H.), University Hospital Basel and Department of Biomedicine, University of Basel, CH-4058 Basel, Switzerland; Department of Nuclear Medicine and Endocrine Oncology (M.K., D.K., B.J.), Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, 44-101 Gliwice, Poland; Grup de Mutagènesi (S.P., R.M., A.V.), Departament de Genètica i de Microbiologia, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallés, Barcelona, Spain; Centro de Investigación Biomédica en Red y Epidemiologia y Salud Pública (S.P., R.M., A.V.), Instituto de Salud Carlos III, 28029 Madrid, Spain; and Center for Primary Health Care Research (K.H., A.F.), Clinical Research Center, Lund University, 205 02 Malmö, Sweden.

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October 2014

GABA release provoked by disturbed Na(+), K(+) and Ca(2+) homeostasis in cerebellar nerve endings: roles of Ca(2+) channels, Na(+)/Ca(2+) exchangers and GAT1 transporter reversal.

Neurochem Int 2014 Jun 13;72:1-9. Epub 2014 Apr 13.

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy; National Institute of Neuroscience, Genoa, Italy. Electronic address:

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June 2014

A new function for glycine GlyT2 transporters: Stimulation of γ-aminobutyric acid release from cerebellar nerve terminals through GAT1 transporter reversal and Ca(2+)-dependent anion channels.

J Neurosci Res 2014 Mar 23;92(3):398-408. Epub 2013 Nov 23.

Department of Pharmacy, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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March 2014

Risk of differentiated thyroid carcinoma and polymorphisms within the susceptibility cancer region 8q24.

Cancer Epidemiol Biomarkers Prev 2013 Nov 5;22(11):2121-5. Epub 2013 Sep 5.

Authors' Affiliations: Department of Biology, University of Pisa, Pisa; Center for Integrated Biology, University of Trento, Trento; Department of Endocrinology and Metabolism, Orthopaedics and Traumatology, Occupational Medicine, University of Pisa, Pisa; and Operative Unit of Laboratory of Clinical Chemistry Analyses, University Hospital of Cisanello, Pisa, Italy.

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November 2013

Medullary thyroid cancer secreting carbohydrate antigen 19-9 (Ca 19-9): a fatal case report.

J Clin Endocrinol Metab 2013 Sep 16;98(9):3550-4. Epub 2013 Jul 16.

Section of Endocrinology, Department of Clinical and Experimental Medicine, and World Health Organization Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders, University Hospital of Pisa, 56126 Pisa, Italy.

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September 2013

Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG).

Neuropharmacology 2013 Mar 31;66:311-6. Epub 2012 May 31.

Department of Experimental Medicine, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.

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March 2013

Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor.

Neurochem Int 2013 Mar 11;62(4):360-6. Epub 2013 Feb 11.

Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.

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March 2013

Calcitonin estimation in patients with nodular goiter and its significance for early detection of MTC: european comments to the guidelines of the American Thyroid Association.

Thyroid Res 2013 Mar 14;6 Suppl 1:S2. Epub 2013 Mar 14.

Department of Endocrinology and Metabolism, University of Pisa, Lungarno Pacinotti 43 - 56126 Pisa, Italy.

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March 2013

Modifications in the papillary thyroid cancer gene profile over the last 15 years.

J Clin Endocrinol Metab 2012 Sep 28;97(9):E1758-65. Epub 2012 Jun 28.

Department of Endocrinology and Metabolism and World Health Organization Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders, University of Pisa, 56124 Pisa, Italy.

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September 2012

RET/PTC Translocations and Clinico-Pathological Features in Human Papillary Thyroid Carcinoma.

Front Endocrinol (Lausanne) 2012 11;3:54. Epub 2012 Apr 11.

Department of Endocrinology and Metabolism, WHO Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders University of Pisa, Pisa, Italy.

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August 2012

GABA transporters mediate glycine release from cerebellum nerve endings: roles of Ca(2+)channels, mitochondrial Na(+)/Ca(2+) exchangers, vesicular GABA/glycine transporters and anion channels.

Neurochem Int 2012 Jul 9;61(2):133-40. Epub 2012 May 9.

Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Italy.

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July 2012

The timing of total thyroidectomy in RET gene mutation carriers could be personalized and safely planned on the basis of serum calcitonin: 18 years experience at one single center.

J Clin Endocrinol Metab 2012 Feb 7;97(2):426-35. Epub 2011 Dec 7.

Department of Endocrinology and Metabolism, World Health Organization Collaborating Center for the Diagnosis and Treatment of Thyroid Cancer and Other Thyroid Diseases, University of Pisa, Pisa, Italy.

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February 2012

Chromosome 10 and RET gene copy number alterations in hereditary and sporadic Medullary Thyroid Carcinoma.

Mol Cell Endocrinol 2012 Jan 16;348(1):176-82. Epub 2011 Aug 16.

Department of Endocrinology and Metabolism, University-Hospital of Pisa, 56100 Pisa, Italy.

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January 2012

Glycine release provoked by disturbed Na⁺, Na⁺ and Ca²⁺ homeostasis in cerebellar nerve endings: roles of Ca²⁺ channels, Na⁺/Ca²⁺ exchangers and GlyT2 transporter reversal.

J Neurochem 2011 Oct 22;119(1):50-63. Epub 2011 Aug 22.

Department of Experimental Medicine, Section of Pharmacology and Toxicology, Genova, Italy.

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October 2011

CDKN1B V109G polymorphism a new prognostic factor in sporadic medullary thyroid carcinoma.

Eur J Endocrinol 2011 Mar 21;164(3):397-404. Epub 2010 Dec 21.

Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale F. Magrassi e A. Lanzara, Seconda Università di Napoli, 80131 Napoli, Italy.

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March 2011

Ionic dysregulations typical of ischemia provoke release of glycine and GABA by multiple mechanisms.

J Neurochem 2010 Aug 26;114(4):1074-84. Epub 2010 May 26.

Department of Experimental Medicine, University of Genova, Genova, Italy.

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August 2010

The GABA B receptor antagonists CGP35348 and CGP52432 inhibit glycine exocytosis: study with GABA B1- and GABA B2-deficient mice.

Pharmacol Res 2010 Jun 4;61(6):547-52. Epub 2010 Feb 4.

Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy.

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June 2010

GABA(B) presynaptic receptors modulate glycine exocytosis from mouse spinal cord and hippocampus glycinergic nerve endings.

Pharmacol Res 2009 Mar 24;59(3):154-9. Epub 2008 Dec 24.

Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy.

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March 2009

BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study.

J Clin Endocrinol Metab 2008 Oct 5;93(10):3943-9. Epub 2008 Aug 5.

Department of Endocrinology, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.

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October 2008

Expression analysis of facilitative glucose transporters (GLUTs) in human thyroid carcinoma cell lines and primary tumors.

Mol Cell Endocrinol 2008 Sep 14;291(1-2):57-62. Epub 2008 May 14.

Department of Endocrinology and Metabolism, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.

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September 2008

Glycinergic nerve endings in hippocampus and spinal cord release glycine by different mechanisms in response to identical depolarizing stimuli.

J Neurochem 2008 Jun;105(6):2179-89

Department of Experimental Medicine, University of Genoa, Genoa, Italy.

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June 2008

Analysis of cancer/testis antigens in sporadic medullary thyroid carcinoma: expression and humoral response to NY-ESO-1.

J Clin Endocrinol Metab 2003 Feb;88(2):748-54

Cancer Bioimmunotherapy Unit, Department of Medical Oncology, Centro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, 33081 Aviano, Italy.

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February 2003