Cristina Rodríguez-Antona

Cristina Rodríguez-Antona

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Cristina Rodríguez-Antona

Cristina Rodríguez-Antona

Publications by authors named "Cristina Rodríguez-Antona"

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Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk.

Authors:
Yaohua Yang Lang Wu Xiang Shu Yingchang Lu Xiao-Ou Shu Qiuyin Cai Alicia Beeghly-Fadiel Bingshan Li Fei Ye Andrew Berchuck Hoda Anton-Culver Susana Banerjee Javier Benitez Line Bjørge James D Brenton Ralf Butzow Ian G Campbell Jenny Chang-Claude Kexin Chen Linda S Cook Daniel W Cramer Anna deFazio Joe Dennis Jennifer A Doherty Thilo Dörk Diana M Eccles Digna Velez Edwards Peter A Fasching Renée T Fortner Simon A Gayther Graham G Giles Rosalind M Glasspool Ellen L Goode Marc T Goodman Jacek Gronwald Holly R Harris Florian Heitz Michelle A Hildebrandt Estrid Høgdall Claus K Høgdall David G Huntsman Siddhartha P Kar Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Anita Koushik Diether Lambrechts Nhu D Le Douglas A Levine Leon F Massuger Keitaro Matsuo Taymaa May Iain A McNeish Usha Menon Francesmary Modugno Alvaro N Monteiro Patricia G Moorman Kirsten B Moysich Roberta B Ness Heli Nevanlinna Håkan Olsson N Charlotte Onland-Moret Sue K Park James Paul Celeste L Pearce Tanja Pejovic Catherine M Phelan Malcolm C Pike Susan J Ramus Elio Riboli Cristina Rodriguez-Antona Isabelle Romieu Dale P Sandler Joellen M Schildkraut Veronica W Setiawan Kang Shan Nadeem Siddiqui Weiva Sieh Meir J Stampfer Rebecca Sutphen Anthony J Swerdlow Lukasz M Szafron Soo Hwang Teo Shelley S Tworoger Jonathan P Tyrer Penelope M Webb Nicolas Wentzensen Emily White Walter C Willett Alicja Wolk Yin Ling Woo Anna H Wu Li Yan Drakoulis Yannoukakos Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2019 02 17;79(3):505-517. Epub 2018 Dec 17.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359948PMC
February 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

Authors:
Yingchang Lu Alicia Beeghly-Fadiel Lang Wu Xingyi Guo Bingshan Li Joellen M Schildkraut Hae Kyung Im Yian A Chen Jennifer B Permuth Brett M Reid Jamie K Teer Kirsten B Moysich Irene L Andrulis Hoda Anton-Culver Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Javier Benitez Line Bjorge James Brenton Ralf Butzow Trinidad Caldes Maria A Caligo Ian Campbell Jenny Chang-Claude Kathleen B M Claes Fergus J Couch Daniel W Cramer Mary B Daly Anna deFazio Joe Dennis Orland Diez Susan M Domchek Thilo Dörk Douglas F Easton Diana M Eccles Peter A Fasching Renée T Fortner George Fountzilas Eitan Friedman Patricia A Ganz Judy Garber Graham G Giles Andrew K Godwin David E Goldgar Marc T Goodman Mark H Greene Jacek Gronwald Ute Hamann Florian Heitz Michelle A T Hildebrandt Claus K Høgdall Antoinette Hollestelle Peter J Hulick David G Huntsman Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Paul James Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Ava Kwong Nhu D Le Goska Leslie Fabienne Lesueur Douglas A Levine Amalia Mattiello Taymaa May Lesley McGuffog Iain A McNeish Melissa A Merritt Francesmary Modugno Marco Montagna Susan L Neuhausen Heli Nevanlinna Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Sara H Olson Håkan Olsson Ana Osorio Sue K Park Michael T Parsons Petra H M Peeters Tanja Pejovic Paolo Peterlongo Catherine M Phelan Miquel Angel Pujana Susan J Ramus Gad Rennert Harvey Risch Gustavo C Rodriguez Cristina Rodríguez-Antona Isabelle Romieu Matti A Rookus Mary Anne Rossing Iwona K Rzepecka Dale P Sandler Rita K Schmutzler Veronica W Setiawan Priyanka Sharma Weiva Sieh Jacques Simard Christian F Singer Honglin Song Melissa C Southey Amanda B Spurdle Rebecca Sutphen Anthony J Swerdlow Manuel R Teixeira Soo H Teo Mads Thomassen Marc Tischkowitz Amanda E Toland Antonia Trichopoulou Nadine Tung Shelley S Tworoger Elizabeth J van Rensburg Adriaan Vanderstichele Ana Vega Digna Velez Edwards Penelope M Webb Jeffrey N Weitzel Nicolas Wentzensen Emily White Alicja Wolk Anna H Wu Drakoulis Yannoukakos Kristin K Zorn Simon A Gayther Antonis C Antoniou Andrew Berchuck Ellen L Goode Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2018 Sep 27;78(18):5419-5430. Epub 2018 Jul 27.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139053PMC
September 2018

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics.

Genet Med 2018 06 26;20(6):622-629. Epub 2017 Oct 26.

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1038/gim.2017.156DOI Listing
June 2018

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

BMC Cancer 2018 May 15;18(1):561. Epub 2018 May 15.

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029, Madrid, Spain.

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http://dx.doi.org/10.1186/s12885-018-4467-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952422PMC
May 2018

mTOR Pathway Mutations and Response to Rapalogs in RCC-Letter.

Clin Cancer Res 2017 09;23(17):5320

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1280DOI Listing
September 2017

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma.

Pharmacogenet Genomics 2017 06;27(6):227-231

aHereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) bOncology Department, Hospital Universitario 12 de Octubre cSpanish Oncology Genitourinary Group (SOGUG) dISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain eDepartment of Clinical Pharmacy and Toxicology fDepartment of Medical Oncology gDepartment of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden hDepartment of Medical Oncology, VU University Medical Center, Amsterdam iDepartment of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands jDepartment of Solid Tumour Oncology, Cleveland Clinic Foundation (CCF) Taussig Cancer Institute, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000280DOI Listing
June 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Authors:
Catherine M Phelan Karoline B Kuchenbaecker Jonathan P Tyrer Siddhartha P Kar Kate Lawrenson Stacey J Winham Joe Dennis Ailith Pirie Marjorie J Riggan Ganna Chornokur Madalene A Earp Paulo C Lyra Janet M Lee Simon Coetzee Jonathan Beesley Lesley McGuffog Penny Soucy Ed Dicks Andrew Lee Daniel Barrowdale Julie Lecarpentier Goska Leslie Cora M Aalfs Katja K H Aben Marcia Adams Julian Adlard Irene L Andrulis Hoda Anton-Culver Natalia Antonenkova Gerasimos Aravantinos Norbert Arnold Banu K Arun Brita Arver Jacopo Azzollini Judith Balmaña Susana N Banerjee Laure Barjhoux Rosa B Barkardottir Yukie Bean Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Marcus Q Bernardini Michael J Birrer Line Bjorge Amanda Black Kenneth Blankstein Marinus J Blok Clara Bodelon Natalia Bogdanova Anders Bojesen Bernardo Bonanni Åke Borg Angela R Bradbury James D Brenton Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Fiona Bruinsma Joan Brunet Bruno Buecher Ralf Butzow Saundra S Buys Trinidad Caldes Maria A Caligo Ian Campbell Rikki Cannioto Michael E Carney Terence Cescon Salina B Chan Jenny Chang-Claude Stephen Chanock Xiao Qing Chen Yoke-Eng Chiew Jocelyne Chiquette Wendy K Chung Kathleen B M Claes Thomas Conner Linda S Cook Jackie Cook Daniel W Cramer Julie M Cunningham Aimee A D'Aloisio Mary B Daly Francesca Damiola Sakaeva Dina Damirovna Agnieszka Dansonka-Mieszkowska Fanny Dao Rosemarie Davidson Anna DeFazio Capucine Delnatte Kimberly F Doheny Orland Diez Yuan Chun Ding Jennifer Anne Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Laure Dossus Mercedes Duran Matthias Dürst Bernd Dworniczak Diana Eccles Todd Edwards Ros Eeles Ursula Eilber Bent Ejlertsen Arif B Ekici Steve Ellis Mingajeva Elvira Kevin H Eng Christoph Engel D Gareth Evans Peter A Fasching Sarah Ferguson Sandra Fert Ferrer James M Flanagan Zachary C Fogarty Renée T Fortner Florentia Fostira William D Foulkes George Fountzilas Brooke L Fridley Tara M Friebel Eitan Friedman Debra Frost Patricia A Ganz Judy Garber María J García Vanesa Garcia-Barberan Andrea Gehrig Aleksandra Gentry-Maharaj Anne-Marie Gerdes Graham G Giles Rosalind Glasspool Gord Glendon Andrew K Godwin David E Goldgar Teodora Goranova Martin Gore Mark H Greene Jacek Gronwald Stephen Gruber Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Thomas V O Hansen Patricia A Harrington Holly R Harris Jan Hauke Alexander Hein Alex Henderson Michelle A T Hildebrandt Peter Hillemanns Shirley Hodgson Claus K Høgdall Estrid Høgdall Frans B L Hogervorst Helene Holland Maartje J Hooning Karen Hosking Ruea-Yea Huang Peter J Hulick Jillian Hung David J Hunter David G Huntsman Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Edwin S Iversen Louise Izatt Angel Izquierdo Anna Jakubowska Paul James Ramunas Janavicius Mats Jernetz Allan Jensen Uffe Birk Jensen Esther M John Sharon Johnatty Michael E Jones Päivi Kannisto Beth Y Karlan Anthony Karnezis Karin Kast Catherine J Kennedy Elza Khusnutdinova Lambertus A Kiemeney Johanna I Kiiski Sung-Won Kim Susanne K Kjaer Martin Köbel Reidun K Kopperud Torben A Kruse Jolanta Kupryjanczyk Ava Kwong Yael Laitman Diether Lambrechts Nerea Larrañaga Melissa C Larson Conxi Lazaro Nhu D Le Loic Le Marchand Jong Won Lee Shashikant B Lele Arto Leminen Dominique Leroux Jenny Lester Fabienne Lesueur Douglas A Levine Dong Liang Clemens Liebrich Jenna Lilyquist Loren Lipworth Jolanta Lissowska Karen H Lu Jan Lubinński Craig Luccarini Lene Lundvall Phuong L Mai Gustavo Mendoza-Fandiño Siranoush Manoukian Leon F A G Massuger Taymaa May Sylvie Mazoyer Jessica N McAlpine Valerie McGuire John R McLaughlin Iain McNeish Hanne Meijers-Heijboer Alfons Meindl Usha Menon Arjen R Mensenkamp Melissa A Merritt Roger L Milne Gillian Mitchell Francesmary Modugno Joanna Moes-Sosnowska Melissa Moffitt Marco Montagna Kirsten B Moysich Anna Marie Mulligan Jacob Musinsky Katherine L Nathanson Lotte Nedergaard Roberta B Ness Susan L Neuhausen Heli Nevanlinna Dieter Niederacher Robert L Nussbaum Kunle Odunsi Edith Olah Olufunmilayo I Olopade Håkan Olsson Curtis Olswold David M O'Malley Kai-Ren Ong N Charlotte Onland-Moret Nicholas Orr Sandra Orsulic Ana Osorio Domenico Palli Laura Papi Tjoung-Won Park-Simon James Paul Celeste L Pearce Inge Søkilde Pedersen Petra H M Peeters Bernard Peissel Ana Peixoto Tanja Pejovic Liisa M Pelttari Jennifer B Permuth Paolo Peterlongo Lidia Pezzani Georg Pfeiler Kelly-Anne Phillips Marion Piedmonte Malcolm C Pike Anna M Piskorz Samantha R Poblete Timea Pocza Elizabeth M Poole Bruce Poppe Mary E Porteous Fabienne Prieur Darya Prokofyeva Elizabeth Pugh Miquel Angel Pujana Pascal Pujol Paolo Radice Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Kerstin Rhiem Patricia Rice Andrea Richardson Mark Robson Gustavo C Rodriguez Cristina Rodríguez-Antona Jane Romm Matti A Rookus Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Helga B Salvesen Dale P Sandler Minouk J Schoemaker Leigha Senter V Wendy Setiawan Gianluca Severi Priyanka Sharma Tameka Shelford Nadeem Siddiqui Lucy E Side Weiva Sieh Christian F Singer Hagay Sobol Honglin Song Melissa C Southey Amanda B Spurdle Zsofia Stadler Doris Steinemann Dominique Stoppa-Lyonnet Lara E Sucheston-Campbell Grzegorz Sukiennicki Rebecca Sutphen Christian Sutter Anthony J Swerdlow Csilla I Szabo Lukasz Szafron Yen Y Tan Jack A Taylor Muy-Kheng Tea Manuel R Teixeira Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Liv Cecilie Vestrheim Thomsen Darcy L Thull Laima Tihomirova Anna V Tinker Marc Tischkowitz Silvia Tognazzo Amanda Ewart Toland Alicia Tone Britton Trabert Ruth C Travis Antonia Trichopoulou Nadine Tung Shelley S Tworoger Anne M van Altena David Van Den Berg Annemarie H van der Hout Rob B van der Luijt Mattias Van Heetvelde Els Van Nieuwenhuysen Elizabeth J van Rensburg Adriaan Vanderstichele Raymonda Varon-Mateeva Ana Vega Digna Velez Edwards Ignace Vergote Robert A Vierkant Joseph Vijai Athanassios Vratimos Lisa Walker Christine Walsh Dorothea Wand Shan Wang-Gohrke Barbara Wappenschmidt Penelope M Webb Clarice R Weinberg Jeffrey N Weitzel Nicolas Wentzensen Alice S Whittemore Juul T Wijnen Lynne R Wilkens Alicja Wolk Michelle Woo Xifeng Wu Anna H Wu Hannah Yang Drakoulis Yannoukakos Argyrios Ziogas Kristin K Zorn Steven A Narod Douglas F Easton Christopher I Amos Joellen M Schildkraut Susan J Ramus Laura Ottini Marc T Goodman Sue K Park Linda E Kelemen Harvey A Risch Mads Thomassen Kenneth Offit Jacques Simard Rita Katharina Schmutzler Dennis Hazelett Alvaro N Monteiro Fergus J Couch Andrew Berchuck Georgia Chenevix-Trench Ellen L Goode Thomas A Sellers Simon A Gayther Antonis C Antoniou Paul D P Pharoah

Nat Genet 2017 May 27;49(5):680-691. Epub 2017 Mar 27.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612337PMC
May 2017

Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.

Pharmacogenomics 2015 26;16(9):929-37. Epub 2015 Jun 26.

Section of Pharmacogenetics, Department of Physiology & Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.2217/pgs.15.46DOI Listing
April 2016

CYP3A5 and ABCB1 polymorphisms as predictors for sunitinib outcome in metastatic renal cell carcinoma.

Eur Urol 2015 Oct 27;68(4):621-9. Epub 2015 Apr 27.

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, The Netherlands; Dutch working group focusing on sunitinib-induced toxicity (SUTOX consortium), The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2015.04.018DOI Listing
October 2015

Renal carcinoma pharmacogenomics and predictors of response: Steps toward treatment individualization.

Urol Oncol 2015 Apr 1;33(4):179-86. Epub 2014 Feb 1.

Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain.

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http://dx.doi.org/10.1016/j.urolonc.2013.09.015DOI Listing
April 2015

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

J Natl Cancer Inst 2015 Mar 11;107(5). Epub 2015 Mar 11.

: Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre, Madrid, Spain (AC, ICM, MCF, AAdC, VM, LIP, RL, AGG, MAR, CRA, MR); Centro de Investigación Biomédica en Red de Enfermedades Raras, Madrid, Spain (AC, LC, LIP, CRA, JS, MU, MR); Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa UAM-CSIC, Universidad Autónoma de Madrid and Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain (LC, JS); Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany (SR, MP, GE); Departments of Pathology (APB) and Endocrinology and Nutrition Service (MC), Hospital 12 de Octubre, Madrid, Spain; Endocrinology Service, Hospital Infanta Sofía, San Sebastián de los Reyes, Spain (SA); Department of Endocrinology and Nutrition Service, Hospital de Fuenlabrada, Madrid, Spain (RVV); Endocrinology Service, Hospital Puerta de Hierro, Majadahonda, Madrid, Spain (JA); Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, L'Hospitalet, Barcelona, Spain (FS, SM, ME); Department of Pathology, MD Anderson Cancer Center Madrid, Madrid, Spain (JFG); Molecular Cytogenetics Group (ARM), Monoclonal Antibodies Unit, Biotechnology Programme (GR), and Familial Cancer Clinical Unit (MU), Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.1093/jnci/djv053DOI Listing
March 2015

Oxaliplatin induced-neuropathy in digestive tumors.

Crit Rev Oncol Hematol 2014 Jan 28;89(1):166-78. Epub 2013 Aug 28.

Medical Oncologist, Chief of Medical Oncology Department, Infanta Sofía University Hospital, San Sebastian de los Reyes, Madrid 28702, Spain.

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http://dx.doi.org/10.1016/j.critrevonc.2013.08.009DOI Listing
January 2014

Influence of RET mutations on the expression of tyrosine kinases in medullary thyroid carcinoma.

Endocr Relat Cancer 2013 Aug 12;20(4):611-9. Epub 2013 Jul 12.

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Center (CNIO), Melchor Fernández Almagro 3, Madrid, Spain.

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http://dx.doi.org/10.1530/ERC-12-0316DOI Listing
August 2013

Molecular markers to predict response to therapy.

Semin Oncol 2013 Aug;40(4):444-58

Genitourinary Tumors Programme Centro Integral Oncologico Clara Campal CIOCC, Madrid, Spain.

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http://dx.doi.org/10.1053/j.seminoncol.2013.05.005DOI Listing
August 2013

Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients.

Pharmacogenomics 2012 Nov;13(14):1583-94

Pharmacogenetics Laboratory, Institute of Biochemistry, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.2217/pgs.12.150DOI Listing
November 2012

Constitutional genetic variants as predictors of antiangiogenic therapy outcome in renal cell carcinoma.

Pharmacogenomics 2012 Nov;13(14):1621-33

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, CNIO, Melchor Fernández Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.2217/pgs.12.142DOI Listing
November 2012

Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues.

Gene 2012 Sep 1;506(1):62-8. Epub 2012 Jul 1.

Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, SE-171 65 Solna, Sweden.

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http://dx.doi.org/10.1016/j.gene.2012.06.053DOI Listing
September 2012

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family.

Genes Chromosomes Cancer 2011 Nov 11;50(11):922-9. Epub 2011 Aug 11.

Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/gcc.20911DOI Listing
November 2011

Microtubule-targeting drugs and personalization of cancer treatment.

Pharmacogenomics 2011 Apr;12(4):449-51

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http://dx.doi.org/10.2217/pgs.11.12DOI Listing
April 2011

Pharmacogenomics of paclitaxel.

Pharmacogenomics 2010 May;11(5):621-3

Human Cancer Genetics Programme, Spanish National Cancer Center (CNIO), Madrid, Spain.

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https://www.futuremedicine.com/doi/10.2217/pgs.10.32
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http://dx.doi.org/10.2217/pgs.10.32DOI Listing
May 2010

Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.

Cytoskeleton (Hoboken) 2010 Apr;67(4):214-23

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Center (CNIO), Melchor Fernández Almagro n 3, Madrid, Spain.

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http://doi.wiley.com/10.1002/cm.20436
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http://dx.doi.org/10.1002/cm.20436DOI Listing
April 2010

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment.

Hum Genet 2010 Jan 8;127(1):1-17. Epub 2009 Oct 8.

Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Center (CNIO), Madrid, Spain.

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http://link.springer.com/content/pdf/10.1007/s00439-009-0748
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http://link.springer.com/10.1007/s00439-009-0748-0
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http://dx.doi.org/10.1007/s00439-009-0748-0DOI Listing
January 2010

Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain.

Eur J Hum Genet 2009 Aug 18;17(8):991-8. Epub 2009 Feb 18.

Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University, Israel.

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http://dx.doi.org/10.1038/ejhg.2009.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986553PMC
August 2009

Determination of CYP2D6 gene copy number by multiplex polymerase chain reaction analysis.

Anal Biochem 2009 Jun 20;389(1):74-6. Epub 2009 Mar 20.

Hereditary Endocrine Cancer Group, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1016/j.ab.2009.03.021DOI Listing
June 2009

Cytochrome P450 2D6 genotyping: potential role in improving treatment outcomes in psychiatric disorders.

CNS Drugs 2009 ;23(3):181-91

Institute of Pharmacology of Natural Products and Clinical Pharmacology, University of Ulm, Ulm, Germany.

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http://link.springer.com/10.2165/00023210-200923030-00001
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http://dx.doi.org/10.2165/00023210-200923030-00001DOI Listing
June 2009

SDHC mutation in an elderly patient without familial antecedents.

Clin Endocrinol (Oxf) 2008 Dec 4;69(6):906-10. Epub 2008 Aug 4.

Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1111/j.1365-2265.2008.03368.xDOI Listing
December 2008

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids.

Pharmacogenomics 2008 Mar;9(3):277-88

Institute of Pharmacology of Natural Products and Clinical Pharmacology, University Ulm, Helmholtzstr. 20, 89081 Ulm, Germany.

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http://dx.doi.org/10.2217/14622416.9.3.277DOI Listing
March 2008

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.

Pharmacol Ther 2007 Dec 9;116(3):496-526. Epub 2007 Oct 9.

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, SE-17177, Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S016372580700201
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http://dx.doi.org/10.1016/j.pharmthera.2007.09.004DOI Listing
December 2007

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas.

Blood 2007 Nov 18;110(9):3345-51. Epub 2007 Jul 18.

Hereditary Endocrine Cancer Group, Spanish National Cancer Centre, C/Melchor Fernández Almagro no. 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1182/blood-2007-02-075036DOI Listing
November 2007

Novel aspects of drug metabolism and transport.

Drug News Perspect 2006 Dec;19(10):637-51

Department of Discovery Drug Metabolism and Pharmacokinetics and Bioanalytical Chemistry, Astra-Zeneca R&D, Molndal, Sweden.

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December 2006

Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

Biochem Biophys Res Commun 2006 Mar 11;341(2):451-8. Epub 2006 Jan 11.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2005.12.200DOI Listing
March 2006

Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles.

Biochem Biophys Res Commun 2005 Dec 13;338(1):299-305. Epub 2005 Sep 13.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.020DOI Listing
December 2005

A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.

J Biol Chem 2005 Aug 2;280(31):28324-31. Epub 2005 Jun 2.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institute, 17177 Stockholm.

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http://dx.doi.org/10.1074/jbc.M502309200DOI Listing
August 2005

Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy.

Philos Trans R Soc Lond B Biol Sci 2005 Aug;360(1460):1563-70

Division of Molecular Toxicology, IMM, Karolinska Institutet, Nobels väg 13, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1098/rstb.2005.1685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569528PMC
August 2005

Transcriptional regulation of the human CYP2A6 gene.

J Pharmacol Exp Ther 2005 May 25;313(2):814-22. Epub 2005 Jan 25.

Institute of Environmental Medicine, Division of Molecular Toxicology, Karolinska Institutet, Stockholm, Sweden.

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http://jpet.aspetjournals.org/content/early/2005/01/25/jpet.
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.104.08157
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http://dx.doi.org/10.1124/jpet.104.081570DOI Listing
May 2005

Identification and phenotype characterization of two CYP3A haplotypes causing different enzymatic capacity in fetal livers.

Clin Pharmacol Ther 2005 Apr;77(4):259-70

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Nobels väg 13, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.clpt.2004.11.003DOI Listing
April 2005

New approaches and applications in chemical biology.

Drug News Perspect 2004 Nov;17(9):594-605

Division of Molecular Toxicology, IMM, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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November 2004

Polymorphic NF-Y dependent regulation of human nicotine C-oxidase (CYP2A6).

Pharmacogenetics 2004 Jun;14(6):369-79

Institute of Environmental Medicine, Division of Molecular Toxicology, Karolinska Institutet, 17177 Stockholm, Sweden.

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June 2004

A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity.

Hum Mutat 2004 Mar;23(3):258-66

Institute of Environmental Medicine, Division of Molecular Toxicology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/humu.20002DOI Listing
March 2004