Publications by authors named "Cristina Mazzoni"

44Publications

Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.

Eur J Med Chem 2020 Jan 2;185:111828. Epub 2019 Nov 2.

Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111828DOI Listing
January 2020

Acid Stress Triggers Resistance to Acetic Acid-Induced Regulated Cell Death through Activation Which Requires in Yeast.

Oxid Med Cell Longev 2019 25;2019:4651062. Epub 2019 Feb 25.

Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, CNR, Via Amendola 165/a, Bari, Italy.

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http://dx.doi.org/10.1155/2019/4651062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410445PMC
April 2019

The hypoxic transcription factor KlMga2 mediates the response to oxidative stress and influences longevity in the yeast Kluyveromyces lactis.

FEMS Yeast Res 2019 05;19(3)

Department Biology and Biotechnology C. Darwin, University of Roma Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy.

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http://dx.doi.org/10.1093/femsyr/foz020DOI Listing
May 2019

Editorial: Yeast cell aging and death.

FEMS Yeast Res 2018 12;18(8)

Department of Biology and Biotechnologies "C. Darwin", University of Rome "Sapienza", Piazzale A. Moro 5, I-00185 Rome, Italy.

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http://dx.doi.org/10.1093/femsyr/foy083DOI Listing
December 2018

Editorial: Cell Stress, Metabolic Reprogramming, and Cancer.

Front Oncol 2018 25;8:236. Epub 2018 Jun 25.

Department of Biology and Biotechnologies "C. Darwin", Pasteur Institute-Cenci Bolognetti Foundation, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3389/fonc.2018.00236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026677PMC
June 2018

RNA stability and metabolism in regulated cell death, aging and diseases.

FEMS Yeast Res 2018 09;18(6)

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185-Rome, Italy.

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http://dx.doi.org/10.1093/femsyr/foy050DOI Listing
September 2018

Guidelines and recommendations on yeast cell death nomenclature.

Microb Cell 2018 Jan 1;5(1):4-31. Epub 2018 Jan 1.

Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.

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http://dx.doi.org/10.15698/mic2018.01.607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772036PMC
January 2018

A role for microbial selection in frescoes' deterioration in Tomba degli Scudi in Tarquinia, Italy.

Sci Rep 2017 07 20;7(1):6027. Epub 2017 Jul 20.

La Sapienza University of Rome, Departement of Biology and Biotechnology "Charles Darwin", Piazzale Aldo Moro, 5, 00185, Rome, Italy.

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http://dx.doi.org/10.1038/s41598-017-06169-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519700PMC
July 2017

Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells.

BMC Complement Altern Med 2017 Apr 5;17(1):200. Epub 2017 Apr 5.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.

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http://dx.doi.org/10.1186/s12906-017-1666-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381082PMC
April 2017

Increased levels of RNA oxidation enhance the reversion frequency in aging pro-apoptotic yeast mutants.

Apoptosis 2017 Feb;22(2):200-206

Department of Biology and Biotechnology "Charles Darwin", Istituto Pasteur Italia-Fondazione Cenci Bolognetti, University "Sapienza" of Rome, Piazzale Aldo Moro 5, Rome, Italy.

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http://dx.doi.org/10.1007/s10495-016-1319-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306349PMC
February 2017

External and internal triggers of cell death in yeast.

Cell Mol Life Sci 2016 Jun 5;73(11-12):2237-50. Epub 2016 Apr 5.

Pasteur Institute-Cenci Bolognetti Foundation; Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.

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http://link.springer.com/10.1007/s00018-016-2197-y
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http://dx.doi.org/10.1007/s00018-016-2197-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887522PMC
June 2016

NEM1 acts as a suppressor of apoptotic phenotypes in LSM4 yeast mutants.

FEMS Yeast Res 2015 Nov 26;15(7). Epub 2015 Aug 26.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185-Rome, Italy

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https://academic.oup.com/femsyr/article/641353/NEM1-acts-as-
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http://dx.doi.org/10.1093/femsyr/fov074DOI Listing
November 2015

Yeast stress, aging, and death.

Oxid Med Cell Longev 2013 2;2013:684395. Epub 2013 Dec 2.

Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, 4710-057 Braga, Portugal ; ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal.

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http://dx.doi.org/10.1155/2013/684395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865740PMC
July 2014

The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2.

FEMS Yeast Res 2014 Feb 30;14(1):2-16. Epub 2013 Oct 30.

Institute of Biomembranes and Bioenergetics, CNR, Bari, Italy.

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http://dx.doi.org/10.1111/1567-1364.12094DOI Listing
February 2014

p53 death signal is mainly mediated by Nuc1(EndoG) in the yeast Saccharomyces cerevisiae.

FEMS Yeast Res 2013 Nov 12;13(7):682-8. Epub 2013 Aug 12.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology "Charles Darwin", University "Sapienza" of Rome, Rome, Italy.

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http://dx.doi.org/10.1111/1567-1364.12067DOI Listing
November 2013

Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes?

Front Oncol 2012 31;2:203. Epub 2012 Dec 31.

Department of Biology and Biotechnology "Charles Darwin", University of Rome "La Sapienza" Rome, Italy ; Pasteur Institute-Cenci Bolognetti Foundation, University of Rome "La Sapienza" Rome, Italy.

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http://journal.frontiersin.org/article/10.3389/fonc.2012.002
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http://dx.doi.org/10.3389/fonc.2012.00203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533236PMC
January 2013

Apple can act as anti-aging on yeast cells.

Oxid Med Cell Longev 2012 30;2012:491759. Epub 2012 Aug 30.

Dipartimento di Biologia e Biotecnologie Charles Darwin, Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Roma, Italy.

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http://www.hindawi.com/journals/omcl/2012/491759/
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http://dx.doi.org/10.1155/2012/491759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437301PMC
January 2013

The importance of mitochondrial fusion in aging.

Cell Cycle 2011 Nov 1;10(21):3631. Epub 2011 Nov 1.

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https://www.tandfonline.com/doi/full/10.4161/cc.10.21.18181
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http://dx.doi.org/10.4161/cc.10.21.18181DOI Listing
November 2011

The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.

J Biol Chem 2011 Nov 27;286(46):39693-702. Epub 2011 Sep 27.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biology and Biotechnology, Sapienza University, 00185-Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M111.279539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220532PMC
November 2011

mRNA stability and control of cell proliferation.

Biochem Soc Trans 2011 Oct;39(5):1461-5

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology Charles Darwin, University of Rome La Sapienza, 00185 Rome, Italy.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0391461
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http://dx.doi.org/10.1042/BST0391461DOI Listing
October 2011

Yeast lsm pro-apoptotic mutants show defects in S-phase entry and progression.

Cell Cycle 2010 Oct 29;9(19):3991-6. Epub 2010 Oct 29.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology Charles Darwin, University of Rome Sapienza, Piazzale Aldo Moro 5, Rome, Italy.

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http://dx.doi.org/10.4161/cc.9.19.13210DOI Listing
October 2010

Fat: Love it to death!

Authors:
Cristina Mazzoni

Cell Cycle 2010 Aug 15;9(16):3149. Epub 2010 Aug 15.

University of Rome La Sapienza Piazzale Aldo Moro, Rome, Italy.

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http://www.tandfonline.com/doi/abs/10.4161/cc.9.16.12834
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http://dx.doi.org/10.4161/cc.9.16.12834DOI Listing
August 2010

Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission.

Aging Cell 2010 Aug 9;9(4):570-9. Epub 2010 Jun 9.

Department of Cell and Developmental Biology, University of Rome, Rome, Italy.

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http://dx.doi.org/10.1111/j.1474-9726.2010.00587.xDOI Listing
August 2010

Swapping of the N-terminus of VDAC1 with VDAC3 restores full activity of the channel and confers anti-aging features to the cell.

FEBS Lett 2010 Jul 29;584(13):2837-44. Epub 2010 Apr 29.

Department of Chemical Sciences, University of Catania, Catania, Italy.

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http://dx.doi.org/10.1016/j.febslet.2010.04.066DOI Listing
July 2010

Characterization of human VDAC isoforms: a peculiar function for VDAC3?

Biochim Biophys Acta 2010 Jun-Jul;1797(6-7):1268-75. Epub 2010 Feb 6.

Department of Chemical Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00052728100004
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http://dx.doi.org/10.1016/j.bbabio.2010.01.031DOI Listing
January 2011

PGK1, the gene encoding the glycolitic enzyme phosphoglycerate kinase, acts as a multicopy suppressor of apoptotic phenotypes in S. cerevisiae.

Yeast 2009 Jan;26(1):31-7

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.

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http://dx.doi.org/10.1002/yea.1647DOI Listing
January 2009

Caspase-dependent apoptosis in yeast.

Biochim Biophys Acta 2008 Jul 29;1783(7):1320-7. Epub 2008 Feb 29.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza Piazzale Aldo Moro 5, Rome, Italy.

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http://dx.doi.org/10.1016/j.bbamcr.2008.02.015DOI Listing
July 2008

The C-terminus of the yeast Lsm4p is required for the association to P-bodies.

FEBS Lett 2007 Oct 14;581(25):4836-40. Epub 2007 Sep 14.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza Piazzale Aldo Moro 5, 00185 Rome, Italy.

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http://dx.doi.org/10.1016/j.febslet.2007.09.009DOI Listing
October 2007

A new regulatory element mediates ethanol repression of KlADH3, a Kluyveromyces lactis gene coding for a mitochondrial alcohol dehydrogenase.

FEMS Yeast Res 2007 Aug 16;7(5):693-701. Epub 2007 May 16.

Department of Cell and Developmental Biology, University of Rome 'La Sapienza', Piazzale Aldo Moro, Rome, Italy.

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http://dx.doi.org/10.1111/j.1567-1364.2007.00250.xDOI Listing
August 2007

Characterization of a Kluyveromyces lactis mutant with altered regulation of mitochondrial alcohol dehydrogenases.

FEMS Yeast Res 2006 May;6(3):421-7

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza, Rome, Italy.

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https://academic.oup.com/femsyr/article-lookup/doi/10.1111/j
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http://dx.doi.org/10.1111/j.1567-1364.2005.00013.xDOI Listing
May 2006

Randomized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome.

J Pediatr Endocrinol Metab 2005 Aug;18(8):761-8

Baystate Medical Center Children's Hospital, Tufts University School of Medicine, Springfield, MA 01199, USA.

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http://dx.doi.org/10.1515/jpem.2005.18.8.761DOI Listing
August 2005

Yeast caspase 1 links messenger RNA stability to apoptosis in yeast.

EMBO Rep 2005 Nov 9;6(11):1076-81. Epub 2005 Sep 9.

Department of Cell and Developmental Biology, Pasteur Institute-Cenci Bolognetti Foundation, University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.

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http://dx.doi.org/10.1038/sj.embor.7400514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1371024PMC
November 2005

HIR1, the co-repressor of histone gene transcription of Saccharomyces cerevisiae, acts as a multicopy suppressor of the apoptotic phenotypes of the LSM4 mRNA degradation mutant.

FEMS Yeast Res 2005 Dec 6;5(12):1229-35. Epub 2005 Sep 6.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza, Piazzale Aldo Moro 5, Italy.

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http://dx.doi.org/10.1016/j.femsyr.2005.07.007DOI Listing
December 2005

Recombinant expression of Pleurotus ostreatus laccases in Kluyveromyces lactis and Saccharomyces cerevisiae.

Appl Microbiol Biotechnol 2005 Dec 14;69(4):428-39. Epub 2005 Jul 14.

Dipartimento di Chimica Organica e Biochimica, Università di Napoli Federico II, Complesso Universitario Monte S. Angelo, via Cinthia, 80126 Naples, Italy.

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http://dx.doi.org/10.1007/s00253-005-0004-zDOI Listing
December 2005

The inactivation of KlNOT4, a Kluyveromyces lactis gene encoding a component of the CCR4-NOT complex, reveals new regulatory functions.

Genetics 2005 Jul 6;170(3):1023-32. Epub 2005 May 6.

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome La Sapienza, 00185 Rome, Italy.

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http://dx.doi.org/10.1534/genetics.105.041863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1451162PMC
July 2005

The bromodomain-containing protein Bdf1p acts as a phenotypic and transcriptional multicopy suppressor of YAF9 deletion in yeast.

Mol Microbiol 2004 Aug;53(3):953-68

Department of Cell and Developmental Biology--Cenci Bolognetti Foundation, University of Rome 'La Sapienza', ple Aldo Moro, I-00185 Rome, Italy.

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http://dx.doi.org/10.1111/j.1365-2958.2004.04184.xDOI Listing
August 2004

A Kluyveromyces lactis mutant in the essential gene KlLSM4 shows phenotypic markers of apoptosis.

FEMS Yeast Res 2003 Oct;4(1):29-35

Department of Cell and Developmental Biology, University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.

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https://academic.oup.com/femsyr/article-lookup/doi/10.1016/S
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http://dx.doi.org/10.1016/S1567-1356(03)00151-XDOI Listing
October 2003

A truncated form of KlLsm4p and the absence of factors involved in mRNA decapping trigger apoptosis in yeast.

Mol Biol Cell 2003 Feb;14(2):721-9

Pasteur Institute-Cenci Bolognetti Foundation, Department of Cell and Developmental Biology, University of Rome, Italy.

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http://www.molbiolcell.org/doi/10.1091/mbc.e02-05-0258
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http://dx.doi.org/10.1091/mbc.e02-05-0258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150003PMC
February 2003