Publications by authors named "Cristian Coarfa"

100Publications

Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data.

Genome Biol 2020 Jul 1;21(1):156. Epub 2020 Jul 1.

Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/s13059-020-02065-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329512PMC
July 2020

BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice.

J Clin Invest 2020 Aug 10. Epub 2020 Aug 10.

Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, and Department of Medicine, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI135922DOI Listing
August 2020

Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects.

J Steroid Biochem Mol Biol 2020 Jun 11;200:105690. Epub 2020 May 11.

Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2020.105690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397709PMC
June 2020

Spatiotemporal Regulation of ΔNp63 by TGFβ-Regulated miRNAs Is Essential for Cancer Metastasis.

Cancer Res 2020 Jul 20;80(13):2833-2847. Epub 2020 Apr 20.

Department of Molecular Oncology, H. Lee Moffitt Cancer Center, Tampa, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385751PMC
July 2020

Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors.

Sci Rep 2020 02 18;10(1):2851. Epub 2020 Feb 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41598-020-59469-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029036PMC
February 2020

Metabolic dysregulation in the Wilson's disease mouse model.

Proc Natl Acad Sci U S A 2020 01 10;117(4):2076-2083. Epub 2020 Jan 10.

Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1914267117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994990PMC
January 2020

Long noncoding RNA BHLHE40-AS1 promotes early breast cancer progression through modulating IL-6/STAT3 signaling.

J Cell Biochem 2020 Jul 7;121(7):3465-3478. Epub 2020 Jan 7.

Department of Biomedical Sciences, Cancer Research Center, University at Albany-SUNY, Rensselaer, New York.

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http://dx.doi.org/10.1002/jcb.29621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263938PMC
July 2020

DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice.

Nat Commun 2019 12 2;10(1):5364. Epub 2019 Dec 2.

Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-019-13339-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889160PMC
December 2019

Erratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915].

Eur Urol Focus 2019 Sep 30;5(5):920. Epub 2019 Aug 30.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Advanced Technology Core, Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2019.08.010DOI Listing
September 2019

The genomic landscape of estrogen receptor α binding sites in mouse mammary gland.

PLoS One 2019 13;14(8):e0220311. Epub 2019 Aug 13.

Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692022PMC
February 2020

Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy.

Cardiovasc Res 2020 May;116(6):1199-1213

Center for Cardiovascular Genetics, Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/cvr/cvz199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177479PMC
May 2020

Short-term RANKL exposure initiates a neoplastic transcriptional program in the basal epithelium of the murine salivary gland.

Cytokine 2019 11 18;123:154745. Epub 2019 Jun 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.154745DOI Listing
November 2019

Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome P450 (Cyp)3a11 gene.

Sci Rep 2019 04 30;9(1):6663. Epub 2019 Apr 30.

Department of Pharmacological and Pharmaceutical Sciences, University of Houston, 4849 Calhoun Rd., Houston, TX, 77204, USA.

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http://dx.doi.org/10.1038/s41598-019-43248-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491424PMC
April 2019

Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy.

Circ Res 2019 04;124(8):1198-1213

From the Center for Cardiovascular Genetics, Department of Medicine, Institute of Molecular Medicine, Texas Heart Institute, University of Texas Health Sciences Center at Houston (S.M.C., P.G., A.J.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459729PMC
April 2019

Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis.

Front Pediatr 2018 10;6:423. Epub 2019 Jan 10.

Department of Pediatric Gastroenterology, University of Texas McGovern Medical School, Houston, TX, United States.

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http://dx.doi.org/10.3389/fped.2018.00423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335364PMC
January 2019

Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage.

Cell 2019 01;176(1-2):127-143.e24

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Graduate Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX 77030, USA; Systems, Synthetic and Physical Biology Program, Rice University, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183162
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http://dx.doi.org/10.1016/j.cell.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344048PMC
January 2019

Correction to: The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast.

J Mammary Gland Biol Neoplasia 2019 Mar;24(1):109-110

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10911-018-9421-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828223PMC
March 2019

MicroRNA-30a as a candidate underlying sex-specific differences in neonatal hyperoxic lung injury: implications for BPD.

Am J Physiol Lung Cell Mol Physiol 2019 01 1;316(1):L144-L156. Epub 2018 Nov 1.

Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine , Houston, Texas.

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http://dx.doi.org/10.1152/ajplung.00372.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383497PMC
January 2019

The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast.

J Mammary Gland Biol Neoplasia 2018 12 18;23(4):237-248. Epub 2018 Oct 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10911-018-9416-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244884PMC
December 2018

Transcriptomic and microRNA analyses of gene networks regulated by eicosapentaenoic acid in brown adipose tissue of diet-induced obese mice.

Biochim Biophys Acta Mol Cell Biol Lipids 2018 12 25;1863(12):1523-1531. Epub 2018 Sep 25.

Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, United States; Obesity Research Cluster, Texas Tech University, Lubbock, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2018.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298436PMC
December 2018

Inositol polyphosphate 4-phosphatase type II regulation of androgen receptor activity.

Oncogene 2019 02 18;38(7):1121-1135. Epub 2018 Sep 18.

Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41388-018-0498-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377303PMC
February 2019

Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1.

Hum Mol Genet 2018 08;27(16):2789-2804

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1093/hmg/ddy192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077786PMC
August 2018

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma.

Oncotarget 2018 04 17;9(29):20323-20338. Epub 2018 Apr 17.

Division of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.24859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945521PMC
April 2018

ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells.

Invest Ophthalmol Vis Sci 2018 01;59(1):132-143

Department of Ophthalmology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1167/iovs.17-22454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769500PMC
January 2018

Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies.

Circ Res 2018 03 9;122(5):678-692. Epub 2018 Jan 9.

From the Center for Cardiovascular Genetics, Institute of Molecular Medicine and Department of Medicine, University of Texas Health Sciences Center at Houston (G.A., P.G., R.L., T.T.W., A.J.M.), Texas Heart Institute (J.T.W., A.J.M.); and Baylor College of Medicine, Houston, TX (C.C.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834384PMC
March 2018

Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs.

Cell Rep 2017 Nov;21(6):1562-1573

Black Family Stem Cell Institute and Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695914PMC
November 2017

Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Cell Discov 2017 26;3:17034. Epub 2017 Sep 26.

Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1038/celldisc.2017.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613224PMC
September 2017

Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway.

Am J Physiol Lung Cell Mol Physiol 2017 Dec 17;313(6):L991-L1005. Epub 2017 Aug 17.

Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas;

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http://dx.doi.org/10.1152/ajplung.00230.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814706PMC
December 2017

Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder.

Eur Urol Focus 2018 12 20;4(6):907-915. Epub 2017 Apr 20.

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Advanced Technology Core, Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650548PMC
December 2018

miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma.

Int J Cancer 2017 11 8;141(10):2062-2075. Epub 2017 Aug 8.

Texas Children's Cancer and Hematology Centers and The Faris D. Virani Ewing Sarcoma Center, Baylor College of Medicine, Houston, TX.

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http://doi.wiley.com/10.1002/ijc.30909
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http://dx.doi.org/10.1002/ijc.30909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603410PMC
November 2017

Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer.

Mol Cancer Res 2017 08 15;15(8):1017-1028. Epub 2017 May 15.

Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, Texas.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685160PMC
August 2017

Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer.

Oncotarget 2017 Jul;8(30):48832-48845

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.18632/oncotarget.16384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564728PMC
July 2017

Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome.

Sci Rep 2017 04 4;7(1):642. Epub 2017 Apr 4.

Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/s41598-017-00516-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428698PMC
April 2017