Cris dos Remedios

Cris dos Remedios

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Cris dos Remedios

Cris dos Remedios

Publications by authors named "Cris dos Remedios"

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Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies.

Heart Fail Rev 2019 Sep;24(5):743-758

Sydney Medical School, University of Sydney, Camperdown, Australia.

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http://dx.doi.org/10.1007/s10741-019-09806-0DOI Listing
September 2019

The Translational Landscape of the Human Heart.

Cell 2019 Jun 30;178(1):242-260.e29. Epub 2019 May 30.

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 13347 Berlin, Germany; Berlin Institute of Health (BIH), 10178 Berlin, Germany; Charité-Universitätsmedizin, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.010DOI Listing
June 2019

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.

J Mol Cell Cardiol 2019 May 27;130:96-106. Epub 2019 Mar 27.

School of Biomedical Sciences and Pharmacy, University of Newcastle and Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.03.018DOI Listing
May 2019

Recollections of 50 years of research in biophysics: a matter of hard work and luck.

Biophys Rev 2019 Apr 27;11(2):135-137. Epub 2019 Feb 27.

Discipline of Anatomy & Histology, Faculty of Medicine and Heath, The University of Sydney, Sydney, 2006, Australia.

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http://dx.doi.org/10.1007/s12551-019-00502-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441438PMC
April 2019

Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy.

Circ Genom Precis Med 2018 12;11(12):e001974

University College London Institute of Cardiovascular Science, London, United Kingdom (C.J.C., P.S., T.A.T., J.C.M., L.R.L., C.G.A.M., W.J.M., P.M.E.).

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http://dx.doi.org/10.1161/CIRCGEN.117.001974DOI Listing
December 2018

3Rs and biophysics.

Biophys Rev 2017 Aug 24;9(4):277-278. Epub 2017 Aug 24.

School of Molecular and Cellular Biology, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1007/s12551-017-0291-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578934PMC
August 2017

An historical perspective of the discovery of titin filaments.

Biophys Rev 2017 Jun 27;9(3):179-188. Epub 2017 Jun 27.

CSIRO, University of Sydney, Sydney, 2006, Australia.

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http://dx.doi.org/10.1007/s12551-017-0269-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498331PMC
June 2017

New insights into real-time multiprotein fluorescence microscopy.

Biophys Rev 2017 Apr 21;9(2):65-66. Epub 2017 Mar 21.

Bosch Institute, The University of Sydney, Anderson Stuart Building F13, Sydney, 2006, Australia.

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http://dx.doi.org/10.1007/s12551-017-0260-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425822PMC
April 2017

A review and summary of the contents of biophysical reviews volume 8, 2016.

Biophys Rev 2017 Feb 7;9(1):1-4. Epub 2017 Feb 7.

Bosch Institute, University of Sydney, Sydney, 2006, Australia.

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http://dx.doi.org/10.1007/s12551-017-0249-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418496PMC
February 2017

On life after Proteomics.

Proteomics 2016 Nov;16(22):2839

Bosch Institute, Discipline of Anatomy & Histology, the University of Sydney, Sydney 2006, Australia.

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http://doi.wiley.com/10.1002/pmic.201600027
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http://dx.doi.org/10.1002/pmic.201600027DOI Listing
November 2016

Biophysical Reviews publications on DNA structure and function that complement this Special Issue on DNA supercoiling.

Biophys Rev 2016 Nov 15;8(Suppl 1):157-158. Epub 2016 Jul 15.

Discipline of Anatomy & Histology, Bosch Institute, Anderson Stuart Building, University of Sydney, Sydney, 2006, Australia.

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http://link.springer.com/10.1007/s12551-016-0213-y
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http://dx.doi.org/10.1007/s12551-016-0213-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425796PMC
November 2016

Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness.

J Physiol 2015 Sep 14;593(17):3899-916. Epub 2015 Jul 14.

Department of Physiology, Institute for Cardiovascular Research, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1113/JP270354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575576PMC
September 2015

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.

J Mol Cell Cardiol 2015 May 11;82:93-103. Epub 2015 Mar 11.

Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands; ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405491PMC
May 2015

Cardiac stem cells: translation to human studies.

Biophys Rev 2015 Mar 3;7(1):127-139. Epub 2014 Dec 3.

Department of Cardiology Westmead Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/s12551-014-0148-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418424PMC
March 2015

Spontaneous oscillatory contraction (SPOC) in cardiomyocytes.

Biophys Rev 2015 Mar 3;7(1):15-24. Epub 2015 Feb 3.

Department of Physics, Faculty of Science and Engineering, Waseda University, 3-4-1, Okubo, Shinjuku-ku, Tokyo, 169-8555, Japan.

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http://dx.doi.org/10.1007/s12551-015-0165-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425754PMC
March 2015

Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations.

Pflugers Arch 2014 Aug 2;466(8):1619-33. Epub 2013 Nov 2.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00424-013-1391-0DOI Listing
August 2014

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.

Cardiovasc Res 2014 Jul 16;103(2):248-57. Epub 2014 May 16.

Department of Physiology, Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The Netherlands ICIN Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvu127DOI Listing
July 2014

PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis.

PLoS One 2013 7;8(10):e74847. Epub 2013 Oct 7.

Laboratory for Physiology, Institute for Cardiovascular Research, VU Medical Center, Amsterdam, The Netherlands ; Johns Hopkins Bayview Proteomics Center, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074847PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792062PMC
June 2014

Protein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertension.

J Am Heart Assoc 2014 Jun 3;3(3):e000716. Epub 2014 Jun 3.

Department of Pulmonology, VU University Medical Center/Institute for Cardiovascular Research, Amsterdam, The Netherlands (S.R., D.S.G.B., N.W., H.J.B., A.V.N., F.S.M.) Department of Physiology, VU University Medical Center/Institute for Cardiovascular Research, Amsterdam, The Netherlands (S.R., L.H., N.W., G.S., C.O., M.G., J.V., F.S.M.).

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http://dx.doi.org/10.1161/JAHA.113.000716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309054PMC
June 2014

Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.

Circulation 2013 Oct 20;128(18):2016-25, 1-10. Epub 2013 Sep 20.

Departments of Pulmonology (S.R., P.T., C.T.-J.G., N.W., P.E.P., A.V.-N., F.S.d.M.), Physiology (S.R., M.L.H., N.W., G.J.S., W.J.P., C.A.C.O., J.v.d.V., F.S.d.M.), Cardiology (M.L.H.), and Medical Physics (J.T.M.), VU University Medical Center/Institute for Cardiovascular Research, Amsterdam, the Netherlands; Université Paris-Sud, Le Kremlin-Bicêtre, France (P.D., C.G., M.H.); INSERM UMR 999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France (P.D., C.G., M.H.); AP-HP, Hôpital de Bicêtre, Service de Pneumologie, DHU Thorax Innovation, Le Kremlin-Bicêtre, France (M.H.); Heart & Lung Transplant Unit, St. Vincent's Hospital and Victor Chang Cardiac Research Institute, Sydney, Australia (P.M.); Muscle Research Unit, Institute for Biomedical Research, University of Sydney, Sydney, Australia (C.d.R.); Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson (C.S., C.G.H., H.L.G.); and ICIN-The Netherlands Heart Institute, Utrecht, the Netherlands (J.v.d.V.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.001873DOI Listing
October 2013

Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis.

Crit Care Med 2011 Dec;39(12):2678-83

Centre for Vascular Research, School of Medical Sciences (Pathology) and Bosch Institute, Sydney, Australia.

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http://dx.doi.org/10.1097/CCM.0b013e31822827f2DOI Listing
December 2011

Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium.

J Muscle Res Cell Motil 2011 Nov 30;32(3):221-33. Epub 2011 Sep 30.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10974-011-9261-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205269PMC
November 2011

A 2-D gel reference map of the basic human heart proteome.

Proteomics 2011 Sep 4;11(17):3582-6. Epub 2011 Aug 4.

UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/pmic.201000182DOI Listing
September 2011

Myocardial and systemic iron depletion in heart failure implications for anemia accompanying heart failure.

J Am Coll Cardiol 2011 Jul;58(5):474-80

Heart Failure Research Group, Baker IDI Heart and Diabetes Institute, St. Kilda Road Central, Melbourne, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S073510971101700
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http://dx.doi.org/10.1016/j.jacc.2011.01.059DOI Listing
July 2011

Is there a connection between ablation of atrial fibrillation and reduced apoptosis?

Cardiology 2010 3;117(3):161-2. Epub 2010 Nov 3.

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http://dx.doi.org/10.1159/000321391DOI Listing
June 2011

Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance.

J Cell Biol 2010 Dec;191(6):1159-72

The Muscle Cell Biology Section, Randall Division of Cell and Molecular Biophysics, British Heart Foundation Research Excellence Centre, King's College London, London SE1 1UL, England, UK.

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http://dx.doi.org/10.1083/jcb.201005060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002041PMC
December 2010

Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization.

J Mol Cell Cardiol 2010 Sep 20;49(3):370-9. Epub 2010 Jun 20.

UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.yjmcc.2010.06.004DOI Listing
September 2010

Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background.

J Mol Cell Cardiol 2010 May 15;48(5):954-63. Epub 2010 Jan 15.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2010.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854313PMC
May 2010

Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.

Basic Res Cardiol 2010 Mar 5;105(2):289-300. Epub 2009 Aug 5.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://link.springer.com/10.1007/s00395-009-0053-z
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http://dx.doi.org/10.1007/s00395-009-0053-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807945PMC
March 2010

Myofilament dysfunction in cardiac disease from mice to men.

J Muscle Res Cell Motil 2008 13;29(6-8):189-201. Epub 2009 Jan 13.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10974-008-9160-yDOI Listing
December 2009

A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients.

J Muscle Res Cell Motil 2009 Dec 6;30(7-8):299-302. Epub 2010 Mar 6.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center Amsterdam, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10974-010-9205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839519PMC
December 2009

Using antibody arrays to detect microparticles from acute coronary syndrome patients based on cluster of differentiation (CD) antigen expression.

Mol Cell Proteomics 2009 Apr 17;8(4):799-804. Epub 2008 Dec 17.

School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney 2006, Australia.

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http://dx.doi.org/10.1074/mcp.M800335-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667358PMC
April 2009

Sarcomeric dysfunction in heart failure.

Cardiovasc Res 2008 Mar 30;77(4):649-58. Epub 2007 Nov 30.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, van der Boechorststraat 7, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvm079DOI Listing
March 2008

Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies.

Proteomics Clin Appl 2007 Oct 11;1(10):1285-90. Epub 2007 Sep 11.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/prca.200600891DOI Listing
October 2007

Mapping the phosphoinositide-binding site on chick cofilin explains how PIP2 regulates the cofilin-actin interaction.

Mol Cell 2006 Nov;24(4):511-22

Department of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, Farmington, Connecticut 06032, USA.

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http://dx.doi.org/10.1016/j.molcel.2006.10.007DOI Listing
November 2006

Thymosin beta4 induces a conformational change in actin monomers.

Biophys J 2006 Feb 4;90(3):985-92. Epub 2005 Nov 4.

Muscle Research Unit, Institute for Biomedical Research, University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1529/biophysj.105.063081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1367123PMC
February 2006

Two opposite effects of cofilin on the thermal unfolding of F-actin: a differential scanning calorimetric study.

Biophys Chem 2004 Jul;110(1-2):119-28

Muscle Research Unit, Department of Anatomy and Histology, The University of Sydney, NSW 2006 Sydney, Australia.

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http://dx.doi.org/10.1016/j.bpc.2004.01.009DOI Listing
July 2004

Cofilin and DNase I affect the conformation of the small domain of actin.

Biophys J 2002 Jun;82(6):3134-43

Muscle Research Unit, Institute for Biomedical Research, Department of Anatomy and Histology, University of Sydney, NSW 2006, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1302102PMC
http://dx.doi.org/10.1016/S0006-3495(02)75655-5DOI Listing
June 2002