Publications by authors named "Craig Stovold"

5 Publications

  • Page 1 of 1

Bioanalysis - but not as we knew it: an AstraZeneca perspective of the last 10 years evolution to meet a diversifying portfolio.

Bioanalysis 2019 Apr 18;11(7):595-599. Epub 2019 Apr 18.

Translational Biomarkers & Bioanalysis, Drug Safety & Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK.

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http://dx.doi.org/10.4155/bio-2019-0037DOI Listing
April 2019

Changing shape: evolving an outsourced bioanalytical strategy to support the changing needs of drug development.

Bioanalysis 2017 Aug 1;9(15):1135-1137. Epub 2017 Aug 1.

Translational Biomarkers & Bioanalysis, Drug Safety & Metabolism, IMED, AstraZeneca, Fleming Building (B623), Babraham Research Campus, C/O Darwin Building 310, Milton Science Park, Cambridge, CB4 OWG, UK.

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http://dx.doi.org/10.4155/bio-2017-0098DOI Listing
August 2017

Recommendations on incurred sample stability (ISS) by GCC.

Bioanalysis 2014 Sep;6(18):2385-90

Quintiles Bioanalytical & ADME Labs, Ithaca, NY, USA.

The topic of incurred sample stability (ISS) has generated considerable discussion within the bioanalytical community in recent years. The subject was an integral part of the seventh annual Workshop on Recent Issues in Bioanalysis (WRIB) held in Long Beach, CA, USA, in April 2013, and at the Global CRO Council for Bioanalysis (GCC) meeting preceding it. Discussion at both events focused on the use of incurred samples for ISS purposes in light of results from a recent GCC survey completed by member companies. This paper reports the consensus resulting from these discussions and serves as a useful reference for depicting ISS issues and concerns, summarizing the GCC survey results and providing helpful recommendations on ISS in the context of bioanalytical method development and application.
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http://dx.doi.org/10.4155/bio.14.155DOI Listing
September 2014

Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2.

BMC Cell Biol 2005 Mar 7;6(1):11. Epub 2005 Mar 7.

School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

Background: The Scar/WAVE family of proteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterised as major regulators of lamellipodia formation downstream of Rac activation and as members of large protein complexes.

Results: We have investigated the interactions of the three human Scar/WAVE isoforms with several previously described binding partners for Scar/WAVE 1 or 2. We find that all three Scar/WAVE isoforms behave similarly and are likely to participate in the same kinds of protein complexes that regulate actin assembly.

Conclusion: Differences between Scar/WAVE proteins are therefore likely to be at the level of tissue distribution or subtle differences in the affinity for specific binding partners.
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http://dx.doi.org/10.1186/1471-2121-6-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC555569PMC
March 2005