Craig S Atwood

Craig S Atwood

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Craig S Atwood

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Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Aug 15. Epub 2019 Aug 15.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
August 2019

Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data.

J Alzheimers Dis 2018 ;63(4):1269-1277

Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.3233/JAD-170847DOI Listing
June 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Human versus non-human sex steroid use in hormone replacement therapies part 1: Preclinical data.

Mol Cell Endocrinol 2019 01 9;480:12-35. Epub 2018 Oct 9.

Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, USA.

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http://dx.doi.org/10.1016/j.mce.2018.10.003DOI Listing
January 2019

Septal hypertrophy and cell cycle re-entry in AD.

Aging (Albany NY) 2019 Jan;11(2):297-298

Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI 53705, USA.

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http://dx.doi.org/10.18632/aging.101777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366959PMC
January 2019

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species.

Geroscience 2017 02 7;39(1):103-116. Epub 2017 Mar 7.

Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1007/s11357-016-9955-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352586PMC
February 2017

Myocardial infarction in the Wisconsin Longitudinal Study: the interaction among environmental, health, social, behavioural and genetic factors.

BMJ Open 2017 01 23;7(1):e011529. Epub 2017 Jan 23.

Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1136/bmjopen-2016-011529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278299PMC
January 2017

Cognitive Effects of Soy Isoflavones in Patients with Alzheimer's Disease.

J Alzheimers Dis 2015 ;47(4):1009-19

Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.3233/JAD-142958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657545PMC
July 2016

The spatiotemporal hormonal orchestration of human folliculogenesis, early embryogenesis and blastocyst implantation.

Mol Cell Endocrinol 2016 07 1;430:33-48. Epub 2016 Apr 1.

Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI 53705, USA; Department of Neurological Surgery, University of Wisconsin-Madison School of Medicine and Public Health, WI 53792, USA.

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http://dx.doi.org/10.1016/j.mce.2016.03.039DOI Listing
July 2016

A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis.

J Alzheimers Dis 2015 ;47(1):33-47

Patiently, LLC, Charleston, SC, USA.

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http://dx.doi.org/10.3233/JAD-143210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807856PMC
June 2016

A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks.

J Alzheimers Dis 2015 ;44(2):549-60

Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI, USA School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.

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http://dx.doi.org/10.3233/JAD-141626DOI Listing
September 2015

Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study.

PLoS Med 2015 Jun 2;12(6):e1001833; discussion e1001833. Epub 2015 Jun 2.

School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America; Geriatric Research, Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States of America; Wisconsin Alzheimer's Disease Research Center, Madison, Wisconsin, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1001833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452757PMC
June 2015

Assessment of genetic and nongenetic interactions for the prediction of depressive symptomatology: an analysis of the Wisconsin Longitudinal Study using machine learning algorithms.

Am J Public Health 2013 Oct 8;103 Suppl 1:S136-44. Epub 2013 Aug 8.

Nicholas S. Roetker, James A. Yonker, Vicky Chang, Carol L. Roan, Pamela Herd, Taissa S. Hauser, and Robert M. Hauser are with the Department of Sociology, University of Wisconsin-Madison. Pamela Herd is also with La Follete School of Public Affairs, University of Wisconsin-Madison. C. David Page is with the Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison. Craig S. Atwood is with the Geriatric Research, Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, WI, and the Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health.

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http://dx.doi.org/10.2105/AJPH.2012.301141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786749PMC
October 2013

Hypothalamic-pituitary-gonadal axis homeostasis predicts longevity.

Age (Dordr) 2013 Feb 4;35(1):129-38. Epub 2011 Dec 4.

Department of Sociology, University of Wisconsin-Madison, Madison, WI, USA.

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http://link.springer.com/10.1007/s11357-011-9342-1
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http://dx.doi.org/10.1007/s11357-011-9342-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543732PMC
February 2013

Is TNF a link between aging-related reproductive endocrine dyscrasia and Alzheimer's disease?

J Alzheimers Dis 2011 ;27(4):691-9

Research School of Biology, Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.3233/JAD-2011-110887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753178PMC
April 2012

Lactate dyscrasia: a novel explanation for amyotrophic lateral sclerosis.

Neurobiol Aging 2012 Mar 11;33(3):569-81. Epub 2010 Jun 11.

Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI 53705, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.04.012DOI Listing
March 2012

Metals and Alzheimer's disease.

Int J Alzheimers Dis 2011 3;2011:659424. Epub 2011 May 3.

Department of Pathology, The University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.4061/2011/659424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100652PMC
July 2011

The reproductive-cell cycle theory of aging: an update.

Exp Gerontol 2011 Feb-Mar;46(2-3):100-7. Epub 2010 Sep 17.

Geriatric Research, Education and Clinical Center, Veterans Administration Hospital and Department of Medicine, University of Wisconsin, Madison, WI 53705, USA.

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http://dx.doi.org/10.1016/j.exger.2010.09.007DOI Listing
April 2011

The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes.

Stem Cell Res Ther 2010 Sep 13;1(4):28. Epub 2010 Sep 13.

Geriatric Research, Education and Clinical Center, Veterans Administration Hospital and Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, 2500 Highland Avenue, Madison, WI 53705, USA.

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http://dx.doi.org/10.1186/scrt28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983441PMC
September 2010

Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells.

J Biol Chem 2009 Aug 19;284(35):23806-17. Epub 2009 Jun 19.

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin and Geriatric Research, Education and Clinical Center, Veterans Affairs Hospital, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1074/jbc.M109.026328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749153PMC
August 2009

Opioid and progesterone signaling is obligatory for early human embryogenesis.

Stem Cells Dev 2009 Jun;18(5):737-40

Department of Medicine, University of Wisconsin, Madison, WI 53705, USA.

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http://dx.doi.org/10.1089/scd.2008.0190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891507PMC
June 2009

Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.

Neoplasia 2009 Apr;11(4):365-76

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin, Veterans Administration Hospital, Madison, WI 53705, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657882PMC
http://dx.doi.org/10.1593/neo.81544DOI Listing
April 2009

Redox active iron accumulation in aceruloplasminemia.

Neuropathology 2008 Oct 15;28(5):466-71. Epub 2008 Feb 15.

Department of Pathology, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1111/j.1440-1789.2008.00901.xDOI Listing
October 2008

Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies.

J Biol Chem 2008 Aug 27;283(33):22550-6. Epub 2008 May 27.

Department of Neurology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1074/jbc.M802088200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504870PMC
August 2008

Reproductive hormones regulate the selective permeability of the blood-brain barrier.

Biochim Biophys Acta 2008 Jun 14;1782(6):401-7. Epub 2008 Mar 14.

Department of Medicine, University of Wisconsin-Madison and Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, 2500 Overlook Terrace, Madison, WI 53705 USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092544390800060
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http://dx.doi.org/10.1016/j.bbadis.2008.02.011DOI Listing
June 2008

Menopause, estrogen, and gonadotropins in Alzheimer's disease.

Adv Clin Chem 2008 ;45:139-53

Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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June 2008

A multi-hit endocrine model of intrinsic adult-onset asthma.

Ageing Res Rev 2008 Apr 31;7(2):114-25. Epub 2007 Dec 31.

Department of Medicine, University of Wisconsin and Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA.

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http://dx.doi.org/10.1016/j.arr.2007.12.002DOI Listing
April 2008

Gonadotropins and cognition in older women.

J Alzheimers Dis 2008 Apr;13(3):267-74

Centre of Excellence for Alzheimer's Disease Research and Care, Hollywood Private Hospital, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Australia.

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April 2008

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele.

BMC Med Genet 2008 Apr 25;9:37. Epub 2008 Apr 25.

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.

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http://dx.doi.org/10.1186/1471-2350-9-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396156PMC
April 2008

Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease.

J Alzheimers Dis 2008 Mar;13(2):187-97

Department of Medicine, Section of Geriatrics and Gerontology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.

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March 2008

Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia.

Redox Rep 2007 ;12(6):257-66

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1179/135100007X239270DOI Listing
January 2008

Amyloid-beta precursor protein expression and modulation in human embryonic stem cells: a novel role for human chorionic gonadotropin.

Biochem Biophys Res Commun 2007 Dec 15;364(3):522-7. Epub 2007 Oct 15.

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin and Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI 53705, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.10.021DOI Listing
December 2007

Leuprolide acetate: a drug of diverse clinical applications.

Expert Opin Investig Drugs 2007 Nov;16(11):1851-63

University of Wisconsin-Madison, Department of Medicine, and Geriatric Research, Education and Clinical Center, William S Middleton Memorial Veterans Administration Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA.

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http://dx.doi.org/10.1517/13543784.16.11.1851 DOI Listing
November 2007

Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes.

Med Hypotheses 2007 13;68(4):735-49. Epub 2006 Nov 13.

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison and Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI 53705, USA.

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http://dx.doi.org/10.1016/j.mehy.2006.08.037DOI Listing
July 2007

Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression.

J Neurochem 2007 Mar 11;100(5):1329-39. Epub 2007 Jan 11.

Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04307.xDOI Listing
March 2007

Gonadotropins: a cohesive gender-based etiology of Alzheimer disease.

Mol Cell Endocrinol 2007 Jan 18;260-262:271-5. Epub 2006 Oct 18.

Department of Pathology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.mce.2006.01.018DOI Listing
January 2007

Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression.

J Endocrinol 2006 Dec;191(3):651-63

Department of Pathology and Laboratory Medicine, Veterans Administration Hospital, University of Wisconsin, 2500 Overlook Terrace, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1677/joe.1.07047DOI Listing
December 2006

Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditis elegans.

BMC Evol Biol 2006 Nov 29;6:103. Epub 2006 Nov 29.

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin and Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI 53705, USA.

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http://dx.doi.org/10.1186/1471-2148-6-103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762030PMC
November 2006

Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice.

Biochim Biophys Acta 2006 Apr 13;1762(4):447-52. Epub 2006 Feb 13.

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.bbadis.2006.01.008DOI Listing
April 2006

Antigonadotropins: a novel strategy to halt Alzheimer's disease progression.

Curr Pharm Des 2006 ;12(6):685-90

Voyager Pharmaceutical Corporation, Raleigh, NC 27615, USA.

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http://dx.doi.org/10.2174/138161206775474288DOI Listing
March 2006

The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target.

Curr Pharm Des 2006 ;12(6):691-7

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106. USA.

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http://dx.doi.org/10.2174/138161206775474305DOI Listing
March 2006

Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis.

Alzheimer Dis Assoc Disord 2005 Apr-Jun;19(2):95-9

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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January 2006

What is aging? What is its role in Alzheimer's disease? What can we do about it?

J Alzheimers Dis 2005 Jun;7(3):247-53; discussion 255-62

Stanford/VA Alzheimer Center, Palo Alto, CA 94304-1207, USA.

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June 2005

Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis.

Ann N Y Acad Sci 2005 Jun;1052:201-9

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Rd., Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1196/annals.1347.020DOI Listing
June 2005

Living and dying for sex. A theory of aging based on the modulation of cell cycle signaling by reproductive hormones.

Gerontology 2004 Sep-Oct;50(5):265-90

Voyager Pharmaceutical Corporation, Raleigh, N.C., USA.

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http://dx.doi.org/10.1159/000079125DOI Listing
April 2005

The gonadotropin connection in Alzheimer's disease.

Endocrine 2005 Apr;26(3):317-26

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Veterans Administration Hospital, Madison, 53705, USA.

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http://dx.doi.org/10.1385/ENDO:26:3:317DOI Listing
April 2005

Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases.

Eur J Pharm Biopharm 2005 Feb;59(2):263-72

Department of Pharmaceutical Sciences, Center for Pharmaceutical Science and Technology, College of Pharmacy, University of Kentucky, Lexington, KY 40536-0082, USA.

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http://dx.doi.org/10.1016/j.ejpb.2004.07.009DOI Listing
February 2005

Dementia and testosterone levels in men.

JAMA 2005 Feb;293(5):551; author reply 552

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http://dx.doi.org/10.1001/jama.293.5.551-bDOI Listing
February 2005

Feedback on a feedback loop: the hypothalamic-pituitary-gonadal axis.

J Alzheimers Dis 2005 Feb;7(1):1-2

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February 2005

Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence.

J Neuropathol Exp Neurol 2005 Feb;64(2):93-103

Section of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, 53705, USA.

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http://dx.doi.org/10.1093/jnen/64.2.93DOI Listing
February 2005

Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides.

J Biol Inorg Chem 2004 Dec 3;9(8):954-60. Epub 2004 Nov 3.

Department of Psychiatry, and Laboratory for Oxidation Biology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

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http://dx.doi.org/10.1007/s00775-004-0602-8DOI Listing
December 2004

The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?

Pharmacol Res 2004 Oct;50(4):397-409

Sir James McCusker Alzheimer's Disease Research Unit, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Hollywood Private Hospital, Monash Avenue, Nedlands, WA 6009, Australia.

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http://dx.doi.org/10.1016/j.phrs.2003.12.028DOI Listing
October 2004

Amyloid-beta: phylogenesis of a chameleon.

Brain Res Brain Res Rev 2004 Aug;46(1):118-20

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http://dx.doi.org/10.1016/j.brainresrev.2004.05.001DOI Listing
August 2004

Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease.

Curr Drug Targets CNS Neurol Disord 2004 Aug;3(4):281-5

Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

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August 2004

Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection.

Acta Neurobiol Exp (Wars) 2004 ;64(1):113-8

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, Ohio 44106, USA.

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July 2004

Neuroprotective properties of Bcl-w in Alzheimer disease.

J Neurochem 2004 Jun;89(5):1233-40

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02416.xDOI Listing
June 2004

Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.

J Neurochem 2004 Feb;88(3):554-63

Department of Medicine, University of Wisconsin-Madison, Geriatrics, Research, Education and Clinical Center, Wm. S. Middleton Memorial Veterans Hospital, 53705, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2003.02196.xDOI Listing
February 2004

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.

Biochemistry 2004 Jan;43(2):560-8

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi0358824DOI Listing
January 2004

Pennington scientific symposium on mechanisms and retardation of aging.

Exp Gerontol 2003 Oct;38(10):1217-26

Section of Geriatrics and Gerontology, University of Wisconsin Medical School, Madison, WI, USA.

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October 2003

Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta.

Brain Res Brain Res Rev 2003 Sep;43(1):1-16

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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September 2003

Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply.

Brain Res Brain Res Rev 2003 Sep;43(1):164-78

School of Medicine, University of Wisconsin and William S. Middleton Memorial Veterans Administration, GRECC 11G, 2500 Overlook Terrace, Madison, WI 53705, USA.

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September 2003

Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants.

Free Radic Biol Med 2003 Apr;34(8):1070-7

Department of Surgery, University of Western Australia, Perth, Western Australia, Australia.

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April 2003

Amyloid-beta: a (life) preserver for the brain.

Neurobiol Aging 2002 Nov-Dec;23(6):1097-9

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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March 2003

Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease.

Biometals 2003 Mar;16(1):77-81

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, Ohio 44106, USA.

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March 2003

Estrogen replacement and risk of Alzheimer disease.

JAMA 2003 Mar;289(9):1100; author reply 1101-2

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http://dx.doi.org/10.1001/jama.289.9.1100-aDOI Listing
March 2003

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.

Biochemistry 2003 Mar;42(10):2768-73

Department of Biochemistry, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1021/bi0272151DOI Listing
March 2003

Cerebral hemorrhage and amyloid-beta.

Science 2003 Feb;299(5609):1014; author reply 1014

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http://dx.doi.org/10.1126/science.299.5609.1014aDOI Listing
February 2003

Iron: a pathological mediator of Alzheimer disease?

Dev Neurosci 2002 ;24(2-3):184-7

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1159/000065696DOI Listing
January 2003

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

Free Radic Biol Med 2002 Dec;33(11):1475-9

Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

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December 2002

Amyloid-beta: a vascular sealant that protects against hemorrhage?

J Neurosci Res 2002 Nov;70(3):356

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106 USA.

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http://dx.doi.org/10.1002/jnr.10388DOI Listing
November 2002

Ill-fated amyloid-beta vaccine.

J Neurosci Res 2002 Aug;69(3):285

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http://dx.doi.org/10.1002/jnr.10316DOI Listing
August 2002

The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications.

CNS Drugs 2002 ;16(5):339-52

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.2165/00023210-200216050-00006DOI Listing
July 2002

Dangers of the amyloid-beta vaccination.

Acta Neuropathol 2002 Jul 16;104(1):110. Epub 2002 May 16.

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http://dx.doi.org/10.1007/s00401-002-0572-2DOI Listing
July 2002

The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease.

Peptides 2002 Jul;23(7):1333-41

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/s0196-9781(02)00069-4DOI Listing
July 2002

Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins.

Peptides 2002 Jul;23(7):1343-50

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/s0196-9781(02)00070-0DOI Listing
July 2002

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

Neurochem Int 2002 May;40(6):527-31

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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May 2002

Involvement of Maillard reactions in Alzheimer disease.

Neurotox Res 2002 May;4(3):191-209

Department of Chemistry, University of Missouri-Rolla, Rolla, MO 65409; Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1080/1029840290007321DOI Listing
May 2002

Could Abeta and AbetaPP be Antioxidants?

J Alzheimers Dis 2000 Jun;2(2):83-84

Laboratory of Oxidation Biology, Genetics and Aging Unit, Massachusetts General Hospital East, Charlestown, MA 02129, USA.

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June 2000