Craig Kinnear

Craig Kinnear

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Craig Kinnear

Craig Kinnear

Publications by authors named "Craig Kinnear"

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Genetic Resistance to Infection and Disease.

Front Immunol 2018 27;9:2219. Epub 2018 Sep 27.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fimmu.2018.02219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170664PMC
October 2019

Neutrophils: Innate Effectors of TB Resistance?

Front Immunol 2018 14;9:2637. Epub 2018 Nov 14.

Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.3389/fimmu.2018.02637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246713PMC
October 2019

Primary immunodeficiency diseases in a tuberculosis endemic region: challenges and opportunities.

Genes Immun 2019 07 6;20(6):447-454. Epub 2018 Sep 6.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://www.nature.com/articles/s41435-018-0041-0
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http://dx.doi.org/10.1038/s41435-018-0041-0DOI Listing
July 2019

Wild-type and mutant (G2019S) leucine-rich repeat kinase 2 (LRRK2) associate with subunits of the translocase of outer mitochondrial membrane (TOM) complex.

Exp Cell Res 2019 Feb 28;375(2):72-79. Epub 2018 Dec 28.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.12.022DOI Listing
February 2019

Evaluating the Accuracy of Imputation Methods in a Five-Way Admixed Population.

Front Genet 2019 5;10:34. Epub 2019 Feb 5.

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fgene.2019.00034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370942PMC
February 2019

The X chromosome and sex-specific effects in infectious disease susceptibility.

Hum Genomics 2019 01 8;13(1). Epub 2019 Jan 8.

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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https://humgenomics.biomedcentral.com/articles/10.1186/s4024
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http://dx.doi.org/10.1186/s40246-018-0185-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325731PMC
January 2019

A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array.

Front Genet 2018 18;9:678. Epub 2019 Jan 18.

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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https://www.frontiersin.org/article/10.3389/fgene.2018.00678
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http://dx.doi.org/10.3389/fgene.2018.00678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346682PMC
January 2019

The arms race between man and Mycobacterium tuberculosis: Time to regroup.

Infect Genet Evol 2018 12 23;66:361-375. Epub 2017 Aug 23.

SA MRC Centre for TB Research, Stellenbosch University, Tygerberg, South Africa; DST/NRF Centre of Excellence for Biomedical TB Research, Stellenbosch University, Tygerberg, South Africa; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.

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http://dx.doi.org/10.1016/j.meegid.2017.08.021DOI Listing
December 2018

Autosomal Dominant IFN-γR1 Deficiency Presenting with both Atypical Mycobacteriosis and Tuberculosis in a BCG-Vaccinated South African Patient.

J Clin Immunol 2018 05 18;38(4):460-463. Epub 2018 May 18.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, 8000, Francie van Zijl Drive, Tygerberg, Cape Town, 7505, South Africa.

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http://link.springer.com/10.1007/s10875-018-0509-8
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http://dx.doi.org/10.1007/s10875-018-0509-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478027PMC
May 2018

Exome Sequencing Identifies a Novel Mutation in Recessive Atypical Combined Immunodeficiency.

Front Immunol 2017 27;8:1624. Epub 2017 Nov 27.

SAMRC Centre for TB Research, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fimmu.2017.01624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712007PMC
November 2017

The role of human host genetics in tuberculosis resistance.

Expert Rev Respir Med 2017 09 20;11(9):721-737. Epub 2017 Jul 20.

a SAMRC Centre for TB Research, DST/NRF Centre of Excellence for Biomedical TB Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences , Stellenbosch University , Cape Town , South Africa.

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http://dx.doi.org/10.1080/17476348.2017.1354700DOI Listing
September 2017

Autophagic flux control in neurodegeneration: Progress and precision targeting-Where do we stand?

Prog Neurobiol 2017 06 3;153:64-85. Epub 2017 Apr 3.

Department of Physiological Sciences, Faculty of Natural Sciences, University of Stellenbosch, Stellenbosch 7600, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2017.03.006DOI Listing
June 2017

Curcumin Rescues a PINK1 Knock Down SH-SY5Y Cellular Model of Parkinson's Disease from Mitochondrial Dysfunction and Cell Death.

Mol Neurobiol 2017 05 22;54(4):2752-2762. Epub 2016 Mar 22.

Division of Molecular Biology & Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s12035-016-9843-0DOI Listing
May 2017

Exome sequencing identifies a novel TTC37 mutation in the first reported case of Trichohepatoenteric syndrome (THE-S) in South Africa.

BMC Med Genet 2017 Mar 14;18(1):26. Epub 2017 Mar 14.

SA MRC Centre for Tuberculosis Research, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, P.O. Box 241, Cape Town, 8000, South Africa.

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http://dx.doi.org/10.1186/s12881-017-0388-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351214PMC
March 2017

Filamin C: a novel component of the KCNE2 interactome during hypoxia.

Cardiovasc J Afr 2016 Jan-Feb;27(1):4-11

DST/NRF Centre of Excellence in Biomedical Tuberculosis Research, SA MRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

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http://dx.doi.org/10.5830/CVJA-2015-049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816932PMC
December 2016

Polymorphisms in the Pattern Recognition Receptor Mincle Gene (CLEC4E) and Association with Tuberculosis.

Lung 2016 10 30;194(5):763-7. Epub 2016 Jun 30.

SA MRC Centre for TB Research, DST/NRF Centre of Excellence for Biomedical TB Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Francie van Zijl Drive, Teaching Building, 4th Floor, Room 4036, Tygerberg, Cape Town, 7505, South Africa.

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http://dx.doi.org/10.1007/s00408-016-9915-yDOI Listing
October 2016

A new tool for prioritization of sequence variants from whole exome sequencing data.

Source Code Biol Med 2016 1;11:10. Epub 2016 Jul 1.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s13029-016-0056-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929716PMC
July 2016

Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson's Disease Patients.

Parkinsons Dis 2016 8;2016:1819209. Epub 2016 Mar 8.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1155/2016/1819209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807059PMC
April 2016

Diagnostic disparity and identification of two TNNI3 gene mutations, one novel and one arising de novo, in South African patients with restrictive cardiomyopathy and focal ventricular hypertrophy.

Cardiovasc J Afr 2015 Mar-Apr;26(2):63-9

SA MRC Centre for Tuberculosis Research, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.5830/CVJA-2015-019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815569PMC
February 2016

Implications of direct-to-consumer whole-exome sequencing in South Africa.

S Afr Med J 2016 Jan 12;106(2):139-40. Epub 2016 Jan 12.

Southern African Society for Human Genetics, Johannesburg, South Africa; Division of Human Genetics, School of Pathology, Faculty of Health Sciences, National Health Laboratory Service, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.7196/SAMJ.2016.v106i2.10534DOI Listing
January 2016

Ascribing novel functions to the sarcomeric protein, myosin binding protein H (MyBPH) in cardiac sarcomere contraction.

Exp Cell Res 2015 Feb 18;331(2):338-51. Epub 2014 Nov 18.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, MRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 19063, Francie van Zijl Drive, Tygerberg 7505, South Africa. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144827140049
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http://dx.doi.org/10.1016/j.yexcr.2014.11.006DOI Listing
February 2015

Neurodegenerative disorders: dysregulation of a carefully maintained balance?

Exp Gerontol 2014 Oct 9;58:279-91. Epub 2014 Sep 9.

Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2014.09.003DOI Listing
October 2014

Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations.

Biochem Biophys Res Commun 2014 May 8;447(2):334-40. Epub 2014 Apr 8.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.bbrc.2014.03.151DOI Listing
May 2014

Cyclopia maculata and Cyclopia subternata (honeybush tea) inhibits adipogenesis in 3T3-L1 pre-adipocytes.

Phytomedicine 2013 Mar 18;20(5):401-8. Epub 2013 Feb 18.

Diabetes Discovery Platform, Medical Research Council, Tygerberg, South Africa.

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http://dx.doi.org/10.1016/j.phymed.2012.12.002DOI Listing
March 2013

Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort.

Prog Neuropsychopharmacol Biol Psychiatry 2012 Oct 13;39(1):163-9. Epub 2012 Jun 13.

Department of Genetics, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

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http://dx.doi.org/10.1016/j.pnpbp.2012.06.006DOI Listing
October 2012

Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population.

Compr Psychiatry 2011 Mar-Apr;52(2):181-7. Epub 2010 Jul 1.

Division of Molecular Biology and Human Genetics, Department Biomedical Sciences, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, South Africa.

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http://linkinghub.elsevier.com/retrieve/pii/S0010440X1000064
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http://dx.doi.org/10.1016/j.comppsych.2010.05.007DOI Listing
June 2011

Comorbid obsessive-compulsive personality disorder in obsessive-compulsive disorder (OCD): a marker of severity.

Prog Neuropsychopharmacol Biol Psychiatry 2011 Jun 14;35(4):1087-92. Epub 2011 Mar 14.

MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry, University of Stellenbosch, South Africa.

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http://dx.doi.org/10.1016/j.pnpbp.2011.03.006DOI Listing
June 2011

Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C.

BMC Cell Biol 2011 May 10;12:18. Epub 2011 May 10.

US/MRC Centre for Molecular and Cellular Biology, Department of Biomedical Sciences, University of Stellenbosch, South Africa.

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http://dx.doi.org/10.1186/1471-2121-12-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103437PMC
May 2011

Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene.

BMC Med Genet 2009 Oct 13;10:105. Epub 2009 Oct 13.

Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Cape Town, 8001, South Africa.

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http://dx.doi.org/10.1186/1471-2350-10-105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767350PMC
October 2009

Cluster analysis of obsessive-compulsive symptomatology: identifying obsessive-compulsive disorder subtypes.

Isr J Psychiatry Relat Sci 2008 ;45(3):164-76

MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry, University of Stellenbosch, South Africa.

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June 2009

Investigating the role of the brain-derived neurotrophic factor (BDNF) val66met variant in obsessive-compulsive disorder (OCD).

World J Biol Psychiatry 2008 ;9(2):126-34

MRC/US Centre for Molecular and Cellular Biology, University of Stellenbosch, Tygerberg, South Africa.

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http://dx.doi.org/10.1080/15622970701245003DOI Listing
September 2008

Genetic correlates in trichotillomania--A case-control association study in the South African Caucasian population.

Isr J Psychiatry Relat Sci 2006 ;43(2):93-101

MRC/US Centre for Molecular and Cellular Biology, University of Stellenbosch, Tygerberg, South Africa.

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September 2006

Hoarding in obsessive-compulsive disorder: clinical and genetic correlates.

J Clin Psychiatry 2005 Sep;66(9):1155-60

MRC Unit on Anxiety Disorders, Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa.

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http://dx.doi.org/10.4088/jcp.v66n0911DOI Listing
September 2005

Cluster analysis of obsessive-compulsive spectrum disorders in patients with obsessive-compulsive disorder: clinical and genetic correlates.

Compr Psychiatry 2005 Jan-Feb;46(1):14-9

MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry, University of Stellenbosch, PO Box 19063, Tygerberg, 7505, Cape Town, South Africa.

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http://linkinghub.elsevier.com/retrieve/pii/S0010440X0400108
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http://dx.doi.org/10.1016/j.comppsych.2004.07.020DOI Listing
April 2005

Dissociative experiences in obsessive-compulsive disorder and trichotillomania: clinical and genetic findings.

Compr Psychiatry 2004 Sep-Oct;45(5):384-91

Medical Research Council Unit on Anxiety Disorders, Department of Psychiatry, University of Stellenboch, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.comppsych.2004.03.010DOI Listing
December 2004

Corrigendum to "gender in obsessive-compulsive disorder: clinical and genetic findings" [Eur. Neuropsychopharmacol. 14 (2004) 105-113].

Eur Neuropsychopharmacol 2004 Oct;14(5):437-45

MRC Unit on Anxiety Disorders, Department of Psychiatry, University of Stellenbosch, Tygerberg, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.euroneuro.2004.05.002DOI Listing
October 2004

Early- versus late-onset obsessive-compulsive disorder: investigating genetic and clinical correlates.

Psychiatry Res 2004 Sep;128(2):175-82

MRC Unit on Anxiety and Stress Disorders, University of Stellenbosch, Medical School, PO Box 19063, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1016/j.psychres.2004.05.007DOI Listing
September 2004

Gender in obsessive-compulsive disorder: clinical and genetic findings.

Eur Neuropsychopharmacol 2004 Mar;14(2):105-13

MRC Unit on Anxiety Disorders, Department of Psychiatry, University of Stellenbosch, P.O. Box 19063, Tygerberg 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S0924-977X(03)00063-4DOI Listing
March 2004

Investigating the role of dopaminergic and serotonergic candidate genes in obsessive-compulsive disorder.

Eur Neuropsychopharmacol 2003 Mar;13(2):93-8

MRC/US Centre for Molecular and Cellular Biology, University of Stellenbosch, P.O. Box 19063, 7505, Tygerberg, South Africa.

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http://dx.doi.org/10.1016/s0924-977x(02)00129-3DOI Listing
March 2003