Publications

The impact of oral Polypodium leucotomos extract on ultraviolet B response: A human clinical study.
J Am Acad Dermatol 2017 Jul 22;77(1):33-41.e1. Epub 2017 Mar 22.
Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Electronic address:

Activating transcription factor 4 underlies the pathogenesis of arsenic trioxide-mediated impairment of macrophage innate immune functions.
Toxicol Appl Pharmacol 2016 Oct 25;308:46-58. Epub 2016 Jul 25.
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address:

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis.
PLoS One 2016 14;11(4):e0153556. Epub 2016 Apr 14.
Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, 35294, United States of America.

In Vivo Suppression of Heat Shock Protein (HSP)27 and HSP70 Accelerates DMBA-Induced Skin Carcinogenesis by Inducing Antigenic Unresponsiveness to the Initiating Carcinogenic Chemical.
J Immunol 2015 May 3;194(10):4796-803. Epub 2015 Apr 3.
Department of Dermatology and Skin Diseases Research Center, University of Alabama, Birmingham, AL 35294; and Veteran Affairs Medical Center, Birmingham, AL 35294.

Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations.
J Immunol 2015 Mar 18;194(6):2683-95. Epub 2015 Feb 18.
Department of Dermatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294; Skin Diseases Research Center, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294; Birmingham, Alabama VA Medical Center, Birmingham, AL 35233



Cyclooxygenases: mediators of UV-induced skin cancer and potential targets for prevention.
J Invest Dermatol 2014 Oct 14;134(10):2497-2502. Epub 2014 Apr 14.
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA; UAB Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA; UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.


Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.
Biochem Biophys Res Commun 2014 Aug 2;451(3):394-401. Epub 2014 Aug 2.
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294-0019, USA; Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:


Photoimmunology.
Dermatol Clin 2014 Jul 5;32(3):277-90, vii. Epub 2014 May 5.
Department of Dermatology, UAB Skin Diseases Research Center, UAB Comprehensive Cancer Center, Birmingham VA Medical Center, University of Alabama at Birmingham, EFH 414, 1720 2nd Avenue South, Birmingham, AL 35294-0009, USA.

Toll-like receptor-4 deficiency enhances repair of UVR-induced cutaneous DNA damage by nucleotide excision repair mechanism.
J Invest Dermatol 2014 Jun 10;134(6):1710-1717. Epub 2013 Dec 10.
Department of Dermatology, Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA; Veteran Affairs Medical Center, Birmingham, Alabama, USA; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address:

A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology.
Cancer Prev Res (Phila) 2014 May 10;7(5):496-504. Epub 2014 Mar 10.
Department of Dermatology and The Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, 101 The City Drive, Orange, CA 92868.


Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway.
Cancer Prev Res (Phila) 2014 Feb 11;7(2):186-98. Epub 2013 Nov 11.
Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019.


Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways.
PLoS One 2014 23;9(1):e86338. Epub 2014 Jan 23.
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America ; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.

Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption.
Toxicol Appl Pharmacol 2013 Nov 14;272(3):879-87. Epub 2013 Aug 14.
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model.
Toxicol Appl Pharmacol 2013 Jan 9;266(2):233-44. Epub 2012 Nov 9.
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019, USA.



Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial.
J Natl Cancer Inst 2010 Dec 29;102(24):1835-44. Epub 2010 Nov 29.
Department of Dermatology, 1530 3rd Ave South, EFH 414, University of Alabama at Birmingham, Birmingham, AL 35294, USA.


IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation.
Carcinogenesis 2009 Nov 16;30(11):1970-7. Epub 2009 Sep 16.
Department of Dermatology, University of Alabama at Birmingham, 1670 University Boulevard, Volker Hall 557, Birmingham, AL 35294, USA.





Osteopontin expression in normal skin and non-melanoma skin tumors.
J Histochem Cytochem 2008 Jan 15;56(1):57-66. Epub 2007 Oct 15.
Department of Nutrition Sciences, 311 Susan Mott Webb Nutrition Sciences Building, 1675 University Boulevard, University of Alabama at Birmingham, Birmingham, Alabama 35295-3360, USA.


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