Publications by authors named "Costantino Pitzalis"

196 Publications

Novel insights into macrophage diversity in rheumatoid arthritis synovium.

Autoimmun Rev 2021 Jan 18:102758. Epub 2021 Jan 18.

INSERM UMR1238, Bone Sarcoma and Remodelling of Calcified Tissues, Nantes University, Nantes, France. Electronic address:

View Article and Find Full Text PDF
January 2021

Elderly-onset rheumatoid arthritis is a unique disease subset associated with poor overall outcomes: Response to the letter by Haroon and Ayamer.

Semin Arthritis Rheum 2020 Dec 18. Epub 2020 Dec 18.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom. Electronic address:

View Article and Find Full Text PDF
December 2020

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors.

Ann Rheum Dis 2020 Nov 26. Epub 2020 Nov 26.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK

View Article and Find Full Text PDF
November 2020

Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis.

Nat Commun 2020 10 27;11(1):5420. Epub 2020 Oct 27.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.

View Article and Find Full Text PDF
October 2020

ROR2 blockade as a therapy for osteoarthritis.

Sci Transl Med 2020 09;12(561)

William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.

View Article and Find Full Text PDF
September 2020

Transforming clinical trials in rheumatology: towards patient-centric precision medicine.

Nat Rev Rheumatol 2020 10 4;16(10):590-599. Epub 2020 Sep 4.

Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.

View Article and Find Full Text PDF
October 2020

Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs.

Front Pharmacol 2020 14;11:1051. Epub 2020 Jul 14.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article and Find Full Text PDF
July 2020

Treatment-resistant synovitis and radiographic progression are increased in elderly-onset rheumatoid arthritis patients: findings from a prospective observational longitudinal early arthritis cohort study.

Semin Arthritis Rheum 2020 08 15;50(4):735-743. Epub 2020 May 15.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

View Article and Find Full Text PDF
August 2020

Tertiary Lymphoid Organs in Rheumatoid Arthritis.

Curr Top Microbiol Immunol 2020 ;426:119-141

Barts and the London School of Medicine & Dentistry, Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, John Vane Science Centre, London, UK.

View Article and Find Full Text PDF
September 2020

H and L Chain Affinity Maturation and/or Fab -Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones.

J Immunol 2020 05 27;204(9):2374-2379. Epub 2020 Mar 27.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom; and

View Article and Find Full Text PDF
May 2020

New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis.

Dis Markers 2020 19;2020:1614627. Epub 2020 Jan 19.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

View Article and Find Full Text PDF
October 2020

M3C: Monte Carlo reference-based consensus clustering.

Sci Rep 2020 02 4;10(1):1816. Epub 2020 Feb 4.

Experimental Medicine and Rheumatology, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, United Kingdom.

View Article and Find Full Text PDF
February 2020

Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4 T Cell Metabolic Rewiring.

Cell Metab 2019 12 7;30(6):1055-1074.e8. Epub 2019 Nov 7.

Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Electronic address:

View Article and Find Full Text PDF
December 2019

Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.

Rheumatology (Oxford) 2020 04;59(4):828-838

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

View Article and Find Full Text PDF
April 2020

Spectrum: fast density-aware spectral clustering for single and multi-omic data.

Bioinformatics 2020 02;36(4):1159-1166

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.

View Article and Find Full Text PDF
February 2020

Efficacy, Safety, and Sample Quality of Ultrasound-Guided Synovial Needle Biopsy in Clinical Practice and Research: A Prospective Observational Study.

Arthritis Care Res (Hoboken) 2020 10;72(10):1497-1505

Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, and Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon Academic Medical Centre, Lisbon, Portugal.

View Article and Find Full Text PDF
October 2020