Costantino Pitzalis

Costantino Pitzalis

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Costantino Pitzalis

Publications by authors named "Costantino Pitzalis"

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Spectrum: Fast density-aware spectral clustering for single and multi-omic data.

Bioinformatics 2019 Sep 10. Epub 2019 Sep 10.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1093/bioinformatics/btz704DOI Listing
September 2019

Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.

Rheumatology (Oxford) 2019 Sep 3. Epub 2019 Sep 3.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/kez358DOI Listing
September 2019

Efficacy, safety and sample quality of ultrasound-guided synovial needle biopsy in clinical practice and research: a prospective observational study.

Arthritis Care Res (Hoboken) 2019 Aug 17. Epub 2019 Aug 17.

Department of Rheumatology, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.

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http://dx.doi.org/10.1002/acr.24050DOI Listing
August 2019

Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis.

J Autoimmun 2019 Jul 2:102297. Epub 2019 Jul 2.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.06.008DOI Listing
July 2019

Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis.

JCI Insight 2019 Jul 11;4(13). Epub 2019 Jul 11.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London (QMUL), London, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.125191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629160PMC
July 2019

Generation of Recombinant Monoclonal Antibodies from Single B Cells Isolated from Synovial Tissue of Rheumatoid Arthritis Patients.

Methods Mol Biol 2018 ;1845:159-187

Centre for Experimental Medicine and Rheumatology, John Vane Science Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-8709-2_10DOI Listing
May 2019

Response to: Can ultrasound of the major salivary glands assess histopathological changes induced by treatment with rituximab in primary Sjögren's syndrome?

Ann Rheum Dis 2019 Apr 13;78(4):e28. Epub 2018 Apr 13.

National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1136/annrheumdis-2018-213340DOI Listing
April 2019

B cells in the formation of tertiary lymphoid organs in autoimmunity, transplantation and tumorigenesis.

Curr Opin Immunol 2019 Apr 22;57:46-52. Epub 2019 Feb 22.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.01.004DOI Listing
April 2019

Mast Cells in Early Rheumatoid Arthritis.

Int J Mol Sci 2019 Apr 25;20(8). Epub 2019 Apr 25.

Department of Translational Medical Sciences (DiSMeT) and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/ijms20082040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515166PMC
April 2019

Wrist ultrasound - the model method for grey-scale and power Doppler scoring.

Ann Rheum Dis 2019 Mar 8;78(3):441-442. Epub 2018 Oct 8.

Barts Health NHS Trust, Mile End Hospital, London, UK.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21397
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http://dx.doi.org/10.1136/annrheumdis-2018-213977DOI Listing
March 2019

IL-36, IL-37, and IL-38 Cytokines in Skin and Joint Inflammation: A Comprehensive Review of Their Therapeutic Potential.

Int J Mol Sci 2019 Mar 13;20(6). Epub 2019 Mar 13.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK.

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http://dx.doi.org/10.3390/ijms20061257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470667PMC
March 2019

The Autoimmune Susceptibility Gene Regulates Macrophage-Mediated Resolution of Inflammation.

J Immunol 2019 Feb 18;202(4):1069-1078. Epub 2019 Jan 18.

University College Dublin Centre for Arthritis Research, Conway Institute, University College Dublin, Dublin D04 W6F6, Ireland.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801155
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http://dx.doi.org/10.4049/jimmunol.1801155DOI Listing
February 2019

A clinical and histopathological analysis of the anti-centromere antibody positive subset of primary Sjögren's syndrome.

Clin Exp Rheumatol 2018 May-Jun;36 Suppl 112(3):145-149. Epub 2018 Aug 14.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, UK.

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November 2018

Characterization of a Synovial B Cell-Derived Recombinant Monoclonal Antibody Targeting Stromal Calreticulin in the Rheumatoid Joints.

J Immunol 2018 09 25;201(5):1373-1381. Epub 2018 Jul 25.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1800346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099528PMC
September 2018

Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis.

Pharmacogenomics J 2018 09 31;18(5):657-664. Epub 2018 Aug 31.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/s41397-018-0040-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150911PMC
September 2018

Role of chemokines in ectopic lymphoid structures formation in autoimmunity and cancer.

J Leukoc Biol 2018 08 27;104(2):333-341. Epub 2018 Jun 27.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1002/JLB.3MR0218-062RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099300PMC
August 2018

Isolation and Characterization of Mouse and Human Follicular Dendritic Cells.

Methods Mol Biol 2017 ;1623:113-123

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-7095-7_10DOI Listing
March 2018

Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages.

EBioMedicine 2018 Mar 7;29:60-69. Epub 2018 Feb 7.

The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom; Centre for inflammation and therapeutic innovation, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925578PMC
March 2018

Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints.

Int J Mol Sci 2018 Feb 9;19(2). Epub 2018 Feb 9.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.

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http://dx.doi.org/10.3390/ijms19020530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855752PMC
February 2018

The Relationship Between Synovial Pathobiology and Magnetic Resonance Imaging Abnormalities in Rheumatoid Arthritis: A Systematic Review.

J Rheumatol 2017 Sep 15;44(9):1311-1324. Epub 2017 Jul 15.

From the Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary, University of London; Department of Radiology, Barts Health UK National Health Service (NHS) Trust; Department of Rheumatology, Barts Health NHS Trust, London; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Centre, Leeds, UK.

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http://dx.doi.org/10.3899/jrheum.161314DOI Listing
September 2017

Stratified medicine in rheumatoid arthritis-the MATURA programme.

Rheumatology (Oxford) 2017 08;56(8):1247-1250

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, London, UK.

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http://dx.doi.org/10.1093/rheumatology/kew369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850849PMC
August 2017

Mast cells in rheumatoid arthritis: friends or foes?

Autoimmun Rev 2017 Jun 12;16(6):557-563. Epub 2017 Apr 12.

William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/j.autrev.2017.04.001DOI Listing
June 2017

Can Synovial Pathobiology Integrate with Current Clinical and Imaging Prediction Models to Achieve Personalized Health Care in Rheumatoid Arthritis?

Front Med (Lausanne) 2017 3;4:41. Epub 2017 May 3.

Department of Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.3389/fmed.2017.00041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413506PMC
May 2017

Identification of Novel Chondroprotective Mediators in Resolving Inflammatory Exudates.

J Immunol 2017 04 27;198(7):2876-2885. Epub 2017 Feb 27.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1601111DOI Listing
April 2017

Targeted therapies: what they teach us about the pathogenesis of psoriasis and psoriatic arthritis.

Expert Rev Clin Immunol 2017 Mar 17;13(3):207-222. Epub 2016 Oct 17.

a Centre for Experimental Medicine and Rheumatology, John Vane Science Centre , William Harvey Research Institute, St. Bartholomew's and Royal London School of Medicine , London , United Kingdom.

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http://dx.doi.org/10.1080/1744666X.2017.1241710DOI Listing
March 2017

Ectopic lymphoid neogenesis in rheumatic autoimmune diseases.

Nat Rev Rheumatol 2017 Mar 9;13(3):141-154. Epub 2017 Feb 9.

Centre for Experimental Medicine and Rheumatology, John Vane Science Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/nrrheum.2016.217DOI Listing
March 2017

Synovial heterogeneity in rheumatoid arthritis: the key for rational patient stratification?

Acta Reumatol Port 2015 Jan-Mar;40(1):6-8

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January 2017

Ultrasound-guided synovial biopsy of the wrist does not alter subsequent clinical or ultrasound disease activity assessments: a prospective study for incorporation of imaging in clinical trials.

Clin Exp Rheumatol 2016 Sep-Oct;34(5):802-807. Epub 2016 Jul 25.

Experimental Medicine and Rheumatology, Queen Mary University of London, William Harvey Research Institute, London, UK.

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January 2017

Lactate at the crossroads of metabolism, inflammation, and autoimmunity.

Eur J Immunol 2017 01 21;47(1):14-21. Epub 2016 Dec 21.

William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1002/eji.201646477DOI Listing
January 2017

Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs.

Ann Rheum Dis 2016 10 9;75(10):1866-75. Epub 2015 Dec 9.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.

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http://ard.bmj.com/content/early/2015/12/09/annrheumdis-2015
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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2015-20835
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http://dx.doi.org/10.1136/annrheumdis-2015-208356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036240PMC
October 2016

Ectopic Lymphoid Structures: Powerhouse of Autoimmunity.

Front Immunol 2016 17;7:430. Epub 2016 Oct 17.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London , London , UK.

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http://journal.frontiersin.org/article/10.3389/fimmu.2016.00
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http://dx.doi.org/10.3389/fimmu.2016.00430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066320PMC
October 2016

Ultrasound of the salivary glands is a strong predictor of labial gland biopsy histopathology in patients with sicca symptoms.

J Oral Pathol Med 2016 Jul 14;45(6):450-4. Epub 2015 Dec 14.

Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/jop.12387DOI Listing
July 2016

Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo.

Ann Rheum Dis 2016 06 19;75(6):1228-35. Epub 2015 Aug 19.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-207316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760904PMC
June 2016

Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology.

Curr Pharm Des 2015 ;21(17):2216-24

Centre for Experimental Medicine and Rheumatology, 2nd Floor John Vane Science Centre, William Harvey Research Institute, Charterhouse Square, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.2174/1381612821666150310145758DOI Listing
May 2016

Reply.

Arthritis Rheumatol 2016 Mar;68(3):769-70

Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/art.39505DOI Listing
March 2016

Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.

J Rheumatol 2016 Jan 1;43(1):208-13. Epub 2015 Jun 1.

From the Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute at Barts, and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico San Matteo Foundation/University of Pavia, Pavia, Italy; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, and Rheumatology Department, Lisbon Academic Medical Centre, Lisbon, Portugal; Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain and Department of Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium; Rheumatology Department, Ambroise Paré Hospital, APHP, Université Versailles Saint Quentin en Yvelines, Inserm U987, Boulogne-Billancourt, France; Rheumatology Department, Hospital Universitario Severo Ochoa, Madrid, Spain; Laboratory for Skeletal Development and Joint Disorders, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; University of Cambridge, Cambridge, UK; GlaxoSmithKline Research and Development, Stevenage, UK; School of Medicine and Medical Science, St. Vincent's University Hospital, Dublin, Ireland; Rheumatology Research Unit, Repatriation General Hospital, Daw Park, South Australia; Dublin Academic Medical Centre, The Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland; Cardiff Institute of Infection and Immunity, Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre, Cardiff, UK; Division of Immunology/Rheumatology, Stanford University School of Medicine, Stanford, California, USA.F. Humby, MRCP; S. Kelly, MRCP, Centre for Experimental Medicine and Rheumatology, William Harvey Research Ins

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http://dx.doi.org/10.3899/jrheum.141199DOI Listing
January 2016

Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis.

Drug Discov Today 2016 Jan 30;21(1):172-179. Epub 2015 Oct 30.

William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/j.drudis.2015.10.014DOI Listing
January 2016

Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy.

Arthritis Res Ther 2016 Jan 20;18:19. Epub 2016 Jan 20.

Pôle de Pathologies Rhumatismales Inflammatoires et Systémiques, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Avenue Hippocrate 10, B2.5390, 1200, Brussels, Belgium.

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http://dx.doi.org/10.1186/s13075-016-0919-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719339PMC
January 2016

A homeostatic function of CXCR2 signalling in articular cartilage.

Ann Rheum Dis 2015 Dec 18;74(12):2207-15. Epub 2014 Aug 18.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-205546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680121PMC
December 2015

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.

Sci Transl Med 2015 Nov;7(315):315ra190

William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1126/scitranslmed.aac5608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034622PMC
November 2015

Rational design of antirheumatic prodrugs specific for sites of inflammation.

Arthritis Rheumatol 2015 Oct;67(10):2661-72

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1002/art.39232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832285PMC
October 2015

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs.

Proc Natl Acad Sci U S A 2015 Sep 18;112(35):11024-9. Epub 2015 Aug 18.

Rheumatology Research Group, Centre for Translational Inflammation Research, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, B15 2TT, United Kingdom; University of Birmingham Research Laboratories, Queen Elizabeth Hospital, Birmingham, B15 2WD, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1503315112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568258PMC
September 2015

Accumulation of self-reactive naïve and memory B cell reveals sequential defects in B cell tolerance checkpoints in Sjögren's syndrome.

PLoS One 2014 23;9(12):e114575. Epub 2014 Dec 23.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114575PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275206PMC
August 2015

Trojan horses and guided missiles: targeted therapies in the war on arthritis.

Nat Rev Rheumatol 2015 Jun 3;11(6):328-37. Epub 2015 Mar 3.

Centre for Experimental Medicine &Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine &Dentistry, Queen Mary University of London, John Vane Building, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/nrrheum.2015.17DOI Listing
June 2015

Do the EULAR Sjögren's syndrome outcome measures correlate with health status in primary Sjögren's syndrome?

Rheumatology (Oxford) 2015 Apr 19;54(4):655-9. Epub 2014 Sep 19.

Newcastle upon Tyne Hospitals NHS Foundation Trust, Musculoskeletal Research Group, Institute of Cellular Medicine & NIHR Biomedical Research Centre for Ageing and Chronic Diseases, Institute of Health and Society, Newcastle University, Newcastle upon Tyne, Musgrove Park Hospital, Taunton and Somerset NHS Foundation Trust, Taunton, University Hospital Birmingham, Birmingham, Great Western Hospitals NHS Foundation Trust, Swindon, Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, Nottingham University Hospital, Nottingham, Gartnavel General Hospital, Glasgow, Barts and the London NHS Trust & Barts and the London School of Medicine and Dentistry, NHS Fife, Whyteman's Brae Hospital, Kirkcaldy, Royal Hampshire County Hospital, Winchester, Royal Derby Hospital, Derby, University College London Hospitals NHS Foundation Trust, London, Queen Elizabeth Hospital, Gateshead, Sunderland Royal Hospital, Sunderland, Southend University Hospital, Royal National Hospital for Rheumatic Diseases, Bath, Portsmouth Hospitals NHS Trust, Aintree University Hospitals, Liverpool, Basildon Hospital, Basildon, Royal Hallamshire Hospital, Sheffield, UK. Newcastle upon Tyne Hospitals NHS Foundation Trust, Musculoskeletal Research Group, Institute of Cellular Medicine & NIHR Biomedical Research Centre for Ageing and Chronic Diseases, Institute of Health and Society, Newcastle University, Newcastle upon Tyne, Musgrove Park Hospital, Taunton and Somerset NHS Foundation Trust, Taunton, University Hospital Birmingham, Birmingham, Great Western Hospitals NHS Foundation Trust, Swindon, Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, Nottingham University Hospital, Nottingham, Gartnavel General Hospital, Glasgow, Barts and the

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http://dx.doi.org/10.1093/rheumatology/keu361DOI Listing
April 2015

Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study.

Arthritis Res Ther 2015 Mar 13;17:58. Epub 2015 Mar 13.

Queen Mary University of London, Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Charterhouse Square, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1186/s13075-015-0567-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476089PMC
March 2015

High expression levels of the B cell chemoattractant CXCL13 in rheumatoid synovium are a marker of severe disease.

Rheumatology (Oxford) 2014 Oct 24;53(10):1886-95. Epub 2014 Apr 24.

Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico San Matteo Foundation/University of Pavia, Italy and Centre for Experimental Medicine and Rheumatology, John Vane Science Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://rheumatology.oxfordjournals.org/content/53/10/1886.fu
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http://www.rheumatology.oxfordjournals.org/cgi/doi/10.1093/r
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http://dx.doi.org/10.1093/rheumatology/keu163DOI Listing
October 2014

Pathogenesis of rheumatoid arthritis: from systemic autoimmunity to localised joint disease.

Drug Discov Today 2014 Aug 21;19(8):1152-4. Epub 2014 May 21.

Centre for Experimental Medicine and Rheumatology, John Vane Science Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.05.009DOI Listing
August 2014

Peripheral and synovial mechanisms of humoral autoimmunity in rheumatoid arthritis.

Drug Discov Today 2014 Aug 29;19(8):1161-5. Epub 2014 May 29.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.05.017DOI Listing
August 2014

Resolution of inflammation: examples of peptidergic players and pathways.

Drug Discov Today 2014 Aug 29;19(8):1166-71. Epub 2014 May 29.

The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.05.020DOI Listing
August 2014

Ectopic lymphoid-like structures in infection, cancer and autoimmunity.

Nat Rev Immunol 2014 Jul 20;14(7):447-62. Epub 2014 Jun 20.

Cardiff Institute for Infection and Immunity, The School of Medicine, Cardiff University, The Tenovus Building, Heath Campus, Cardiff CF14 4XN, Wales, UK.

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http://dx.doi.org/10.1038/nri3700DOI Listing
July 2014

EBV and other viruses as triggers of tertiary lymphoid structures in primary Sjögren's syndrome.

Expert Rev Clin Immunol 2014 Apr 25;10(4):445-55. Epub 2014 Feb 25.

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1586/1744666X.2014.892417DOI Listing
April 2014

Multi-therapeutic potential of autoantibodies induced by immune complexes trapped on follicular dendritic cells.

Hum Vaccin Immunother 2013 Nov 8;9(11):2434-44. Epub 2013 Jul 8.

Centre for Experimental Medicine and Rheumatology; William Harvey Research Institute; Barts and the London School of Medicine and Dentistry; Queen Mary University of London; London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981854PMC
http://dx.doi.org/10.4161/hv.25596DOI Listing
November 2013