Publications by authors named "Cor Lieftink"

30Publications

The RECQL helicase prevents replication fork collapse during replication stress.

Life Sci Alliance 2020 Oct 20;3(10). Epub 2020 Aug 20.

Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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http://dx.doi.org/10.26508/lsa.202000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441523PMC
October 2020

High-throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells.

Eur J Immunol 2020 01 14;50(1):73-85. Epub 2019 Nov 14.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Department of Pediatric Immunology, Rheumatology and Infectious diseases, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.201948241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972998PMC
January 2020

CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.

Gut 2020 Apr 13;69(4):727-736. Epub 2019 Sep 13.

Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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http://dx.doi.org/10.1136/gutjnl-2019-318506DOI Listing
April 2020

Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer.

J Hepatol 2018 Nov 18;69(5):1057-1065. Epub 2018 Jul 18.

Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183218
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http://dx.doi.org/10.1016/j.jhep.2018.07.004DOI Listing
November 2018

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

Nat Med 2018 07 28;24(7):961-967. Epub 2018 May 28.

Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41591-018-0023-9DOI Listing
July 2018

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.

Oncogene 2018 08 15;37(33):4611-4625. Epub 2018 May 15.

Division of Molecular Carcinogenesis and Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.

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http://dx.doi.org/10.1038/s41388-018-0300-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095834PMC
August 2018

A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma.

Cell Res 2018 06 5;28(6):690-692. Epub 2018 Mar 5.

Division of Molecular Carcinogenesis, Oncode Institute, Cancer Genomics Centre Netherlands, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41422-018-0020-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993748PMC
June 2018

PIM Kinases Are a Potential Prognostic Biomarker and Therapeutic Target in Neuroblastoma.

Mol Cancer Ther 2018 04 13;17(4):849-857. Epub 2018 Feb 13.

Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0868DOI Listing
April 2018

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

Oncotarget 2017 Sep 19;8(43):73925-73937. Epub 2017 May 19.

Department of Head and Neck Oncology and Surgery, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.18034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650312PMC
September 2017

High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.

Cell Rep 2017 Oct;21(3):773-783

Division of Molecular Carcinogenesis, Cancer Genomics Centre, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.09.085DOI Listing
October 2017

A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma.

Eur Urol 2017 06 17;71(6):858-862. Epub 2017 Jan 17.

Division of Molecular Carcinogenesis, Cancer Genomics Netherlands, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Division of Medical Oncology, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.01.021DOI Listing
June 2017

TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming.

Stem Cells 2017 01 6;35(1):147-157. Epub 2016 Jul 6.

Division of Molecular Genetics, NKI Robotics and Screening Center, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/stem.2453DOI Listing
January 2017

Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation.

Chromosoma 2017 08 29;126(4):473-486. Epub 2016 Jun 29.

Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00412-016-0607-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509784PMC
August 2017

Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1R.

Mol Cancer Ther 2016 07 11;15(7):1545-56. Epub 2016 May 11.

Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands. Cancer Systems Biology Center (CSBC), The Netherlands Cancer Institute, Amsterdam, the Netherlands. The NKI Robotics and Screening Center (NRSC), The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0865DOI Listing
July 2016

FGFR1 Is a Potential Prognostic Biomarker and Therapeutic Target in Head and Neck Squamous Cell Carcinoma.

Clin Cancer Res 2016 08 2;22(15):3884-93. Epub 2016 Mar 2.

Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands. Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1874DOI Listing
August 2016

Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma.

Mol Cancer Res 2016 05 19;14(5):411-22. Epub 2016 Jan 19.

Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands. Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://mcr.aacrjournals.org/content/14/5/411.full-text.pdf
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http://dx.doi.org/10.1158/1541-7786.MCR-15-0291-TDOI Listing
May 2016

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.

Cell Rep 2015 Sep 10;12(12):1978-85. Epub 2015 Sep 10.

Cancer Genomics Centre Netherlands, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.037DOI Listing
September 2015

RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.

Cell Rep 2014 Sep 4;8(5):1475-83. Epub 2014 Sep 4.

Department of Oncology, University of Torino, Str prov 142 Km 3.95, Candiolo, 10060 Torino, Italy; Candiolo Cancer Institute-FPO, IRCCS, Str prov 142 Km 3.95, Candiolo, 10060 Torino, Italy. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00617-2.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400617
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http://dx.doi.org/10.1016/j.celrep.2014.07.033DOI Listing
September 2014