Constantin Georgescu

Constantin Georgescu

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Constantin Georgescu

Constantin Georgescu

Publications by authors named "Constantin Georgescu"

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28Publications

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Dimethyl fumarate mitigates optic neuritis.

Mol Vis 2019 22;25:446-461. Epub 2019 Aug 22.

Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707756PMC
August 2019

Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors.

J Exp Med 2019 Apr 21;216(4):884-899. Epub 2019 Mar 21.

Oklahoma Medical Research Foundation, Program in Arthritis and Clinical Immunology, Oklahoma City, OK

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http://dx.doi.org/10.1084/jem.20182100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446881PMC
April 2019

ARID3a gene profiles are strongly associated with human interferon alpha production.

J Autoimmun 2019 Jan 5;96:158-167. Epub 2018 Oct 5.

Department of Medicine, Oklahoma City, OK, USA; Department of Microbiology and Immunology, Oklahoma City, OK, USA; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183043
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http://dx.doi.org/10.1016/j.jaut.2018.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497177PMC
January 2019

Algorithmic identification of discrepancies between published ratios and their reported confidence intervals and P-values.

Bioinformatics 2018 05;34(10):1758-1766

Arthritis and Clinical Immunology Research Program, Division of Genomics and Data Sciences, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104-5005.

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https://academic.oup.com/bioinformatics/article/34/10/1758/4
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http://dx.doi.org/10.1093/bioinformatics/btx811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946902PMC
May 2018

Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis.

Mol Vis 2016 30;22:1503-1513. Epub 2016 Dec 30.

Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204460PMC
January 2018

Predictive bioinformatics identifies novel regulators of proliferation in a cancer stem cell model.

Stem Cell Res 2018 01 21;26:1-7. Epub 2017 Nov 21.

Cell Cycle and Cancer Biology Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899939PMC
January 2018

DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation.

Genome Res 2017 08 16;27(8):1406-1416. Epub 2017 May 16.

Cell Cycle and Cancer Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA.

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http://dx.doi.org/10.1101/gr.218602.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538556PMC
August 2017

Use it or lose it: citations predict the continued online availability of published bioinformatics resources.

Nucleic Acids Res 2017 04;45(7):3627-3633

Computer Science Department, Boston University, 111 Cummington Mall, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/nar/gkx182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397159PMC
April 2017

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.

Geroscience 2017 04 13;39(2):129-145. Epub 2017 Apr 13.

Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, 975 NE 10th Street, SLY-BRC 1303, Oklahoma City, OK, 73104, USA.

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http://dx.doi.org/10.1007/s11357-017-9971-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411370PMC
April 2017

Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice.

Mol Vis 2016 11;22:332-41. Epub 2016 Apr 11.

Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830397PMC
November 2016

Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons.

BMC Neurosci 2015 Nov 13;16:76. Epub 2015 Nov 13.

Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 Northeast 13th Street, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1186/s12868-015-0194-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644300PMC
November 2015

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.

Sci Signal 2014 Oct 14;7(347):ra97. Epub 2014 Oct 14.

Cardiovascular Biology Program, Oklahoma Medical Research Foundation, Oklahoma, OK 73104, USA. Department of Biochemistry and Molecular Biology, University of Oklahoma Health Science Center, Oklahoma, OK 73104, USA.

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http://dx.doi.org/10.1126/scisignal.2005413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226761PMC
October 2014

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

A gene regulatory network armature for T lymphocyte specification.

Proc Natl Acad Sci U S A 2008 Dec 22;105(51):20100-5. Epub 2008 Dec 22.

Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0806501105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629331PMC
December 2008

A systems biology approach for pathway level analysis.

Genome Res 2007 Oct 4;17(10):1537-45. Epub 2007 Sep 4.

Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1101/gr.6202607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1987343PMC
October 2007

Onto-Tools: new additions and improvements in 2006.

Nucleic Acids Res 2007 Jul 21;35(Web Server issue):W206-11. Epub 2007 Jun 21.

Department of Computer Science, Wayne State University, 431 State Hall, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1093/nar/gkm327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933142PMC
July 2007