Connie Celum

Connie Celum

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Connie Celum

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Doxycycline prophylaxis for bacterial sexually transmitted infections.

Clin Infect Dis 2019 Sep 1. Epub 2019 Sep 1.

Division of Infectious Disease and Department of Epidemiology, UCLA David Geffen School of Medicine and Fielding School of Public Health, Los Angeles, California, United States.

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https://academic.oup.com/cid/advance-article/doi/10.1093/cid
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http://dx.doi.org/10.1093/cid/ciz866DOI Listing
September 2019

Ethical considerations for new HIV prevention trials.

Lancet HIV 2019 Aug 17;6(8):e489-e491. Epub 2019 Jun 17.

Beth Israel Deaconess Medical Center, Harvard Medical School and Fenway Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/S2352-3018(19)30184-5DOI Listing
August 2019

Perceptions of pregnancy occurring among HIV-serodiscordant couples in Kenya.

Reprod Health 2019 Jun 18;16(1):85. Epub 2019 Jun 18.

Department of Global Health, University of Washington, 325 Ninth Avenue Box 359927, Seattle, WA, 98104, USA.

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http://dx.doi.org/10.1186/s12978-019-0751-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582525PMC
June 2019

Reaching the 90-90-90 target: lessons from HIV self-testing.

Lancet HIV 2019 02 21;6(2):e68-e69. Epub 2018 Dec 21.

Departments of Global Health, Medicine and Epidemiology, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/S2352-3018(18)30289-3DOI Listing
February 2019

Quadrivalent HPV vaccine in HIV-1-infected early adolescent girls and boys in Kenya: Month 7 and 12 post vaccine immunogenicity and correlation with immune status.

Vaccine 2018 11 5;36(46):7025-7032. Epub 2018 Oct 5.

Department of Laboratory Medicine, University of Washington, Seattle, WA, USA; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Departments of Medicine, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.vaccine.2018.09.059DOI Listing
November 2018

Modeling HIV disease progression and transmission at population-level: The potential impact of modifying disease progression in HIV treatment programs.

Epidemics 2018 06 5;23:34-41. Epub 2017 Dec 5.

Department of Medicine, University of Washington, Seattle, WA, USA; Department of Global Health, University of Washington, 325 9th Ave., Box 359927, Seattle, WA 98104-2420, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Division of Allergy and Infectious Disease, University of Washington, 1959 NE Pacific St., Box 356423, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.epidem.2017.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975109PMC
June 2018

Brief Report: Context Matters: PrEP Adherence is Associated With Sexual Behavior Among HIV Serodiscordant Couples in East Africa.

J Acquir Immune Defic Syndr 2017 12;76(5):488-492

*MGH Global Health, Boston, MA; †Kenya Medical Research Institute, Thika, Kenya; ‡Infectious Disease Institute, Kampala, Uganda; §Department of Global Health, University of Washington, Seattle, WA; ‖Mbarara University of Science and Technology, Mbarara, Uganda; and ¶Oregon Health and Sciences University-Portland State University School of Public Health, Portland, OR.

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http://dx.doi.org/10.1097/QAI.0000000000001548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680116PMC
December 2017

Closing the gaps in the HIV care continuum.

PLoS Med 2017 Nov 21;14(11):e1002443. Epub 2017 Nov 21.

Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697801PMC
November 2017

Highly conserved intragenic HSV-2 sequences: Results from next-generation sequencing of HSV-2 U and U regions from genital swabs collected from 3 continents.

Virology 2017 10 13;510:90-98. Epub 2017 Jul 13.

Department of Medicine, University of Washington, USA; Department of Laboratory Medicine, University of Washington, USA; Department of Global Health, University of Washington, USA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, USA; Benaroya Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.virol.2017.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565707PMC
October 2017

Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP Study.

Lancet HIV 2017 10 18;4(10):e449-e456. Epub 2017 Jul 18.

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/S2352-3018(17)30110-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649365PMC
October 2017

Preventing HIV among adolescents with oral PrEP: observations and challenges in the United States and South Africa.

J Int AIDS Soc 2016 18;19(7(Suppl 6)):21107. Epub 2016 Oct 18.

The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071778PMC
http://dx.doi.org/10.7448/IAS.19.7.21107DOI Listing
September 2017

The effect of oral preexposure prophylaxis on the progression of HIV-1 seroconversion.

AIDS 2017 09;31(14):2007-2016

aVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center bDepartment of Laboratory Medicine cDepartment of Global Health dDepartment of Epidemiology eDepartment of Medicine fDepartment of Pediatrics, University of Washington, Seattle, Washington gDivision of Global Health Protection, Center for Global Health, CDC, Atlanta, Georgia, USA hDepartments of Medical Microbiology and Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada iDepartment of Microbiology and immunology, Indiana University, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578893PMC
September 2017

Brief Report: Medication Sharing Is Rare Among African HIV-1 Serodiscordant Couples Enrolled in an Efficacy Trial of Oral Pre-exposure Prophylaxis (PrEP) for HIV-1 Prevention.

J Acquir Immune Defic Syndr 2017 06;75(2):184-189

*Department of Epidemiology, University of Washington, Seattle, WA; †Center for Global Health and Department of Medicine, Massachusetts General Hospital, Boston, MA; ‡Departments of Pathology and Medicine, Johns Hopkins University, Baltimore, MD; §Department of Epidemiology and Biostatistics, Makerere University, Kampala, Uganda; ‖Division of Clinical Pharmacology and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ¶Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, WA; #Department of Global Health, University of Washington, Seattle, WA; **Department of Medicine, University of Manitoba, Winnipeg, Canada; ††Oregon Health and Sciences University and Portland State University School of Public Health, Portland, OR; and ‡‡Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/QAI.0000000000001356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432041PMC
June 2017

Community-based strategies to strengthen men's engagement in the HIV care cascade in sub-Saharan Africa.

PLoS Med 2017 04 11;14(4):e1002262. Epub 2017 Apr 11.

Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388461PMC
April 2017

Effect of Pregnancy on Response to Antiretroviral Therapy in HIV-Infected African Women.

J Acquir Immune Defic Syndr 2017 Jan;74(1):38-43

*Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA; Departments of †Epidemiology; ‡Global Health, University of Washington, Seattle, WA; §Sexual, Reproductive, Adolescent and Child Health Research Program, Kenya Medical Research Institute, Nairobi, Kenya; ‖Contraceptive Technology Innovation Department, FHI 360, Durham, NC; ¶Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center, Seattle, WA; Departments of #Medicine; and **Pediatrics, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/QAI.0000000000001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147030PMC
January 2017

Antiretroviral Therapy Initiation Is Not Associated With Risky Sexual Behavior Among Heterosexual Human Immunodeficiency Virus-Infected Persons in Serodiscordant Partnerships.

Sex Transm Dis 2017 01;44(1):57-61

From the Departments of *Global Health; †Epidemiology; ‡Medicine, University of Washington, Seattle, WA; §School of Public Health, Jomo Kenyatta University of Agriculture and Technology, Kenya; and ¶Department of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.

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https://insights.ovid.com/crossref?an=00007435-201701000-000
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http://dx.doi.org/10.1097/OLQ.0000000000000534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145755PMC
January 2017

Counseling Framework for HIV-Serodiscordant Couples on the Integrated Use of Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention.

J Acquir Immune Defic Syndr 2017 01;74 Suppl 1:S15-S22

Departments of *Global Health; †Epidemiology; ‡Medicine, University of Washington, Seattle, WA; §Centres for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; ‖Infectious Disease Institute, Makerere University, Kampala, Uganda; ¶Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya; #Kabwohe Clinical Research Center, Kabwohe, Uganda; **Department of Public and Community Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya; and ††Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000001210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147040PMC
January 2017

Herpes Simplex Virus Suppressive Therapy in Herpes Simplex Virus-2/Human Immunodeficiency Virus-1 Coinfected Women Is Associated With Reduced Systemic CXCL10 But Not Genital Cytokines.

Sex Transm Dis 2016 12;43(12):761-764

From the *Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; Departments of †Global Health, ‡Medicine, §Epidemiology and ∥Laboratory Medicine, University of Washington, Seattle, WA; and ¶Investigaciones Medicas en Salud (INMENSA), Lima, Peru.

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http://dx.doi.org/10.1097/OLQ.0000000000000523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117823PMC
December 2016

Intimate Partner Violence and Adherence to HIV Pre-exposure Prophylaxis (PrEP) in African Women in HIV Serodiscordant Relationships: A Prospective Cohort Study.

J Acquir Immune Defic Syndr 2016 11;73(3):313-322

*Department of Epidemiology, University of Washington, Seattle, WA; †Department of Medicine and Center for Global Health, Massachusetts General Hospital, Boston, MA; ‡Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA; Departments of §Global Health; ‖Medicine, University of Washington, Seattle, WA; ¶Kenya Medical Research Institute, Nairobi, Kenya; #Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA; **Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA; ††Centers for Disease Control and Prevention, Atlanta, GA; ‡‡Department of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya; §§Department of Medicine, University of Manitoba, Winnipeg, Canada; ‖‖Kabwohe Clinical Research Center, Kabwohe, Uganda; ¶¶Department of Reproductive Health, Moi University, Eldoret, Kenya; and ##Kenyatta National Hospital, Nairobi, Kenya.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065369PMC
http://dx.doi.org/10.1097/QAI.0000000000001093DOI Listing
November 2016

Development and Evaluation of a Modified Fourth-Generation Human Immunodeficiency Virus Enzyme Immunoassay for Cross-Sectional Incidence Estimation in Clade B Populations.

AIDS Res Hum Retroviruses 2016 08 5;32(8):756-62. Epub 2016 May 5.

1 Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Baltimore, Maryland.

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http://dx.doi.org/10.1089/AID.2015.0198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971410PMC
August 2016

HIV Transmission Risk Persists During the First 6 Months of Antiretroviral Therapy.

J Acquir Immune Defic Syndr 2016 08;72(5):579-84

Departments of *Global Health; †Epidemiology; ‡Medicine; §Laboratory Medicine, University of Washington, Seattle, WA; ‖Division of Infectious Diseases and Tropical Pediatrics, University of Maryland, Baltimore, MD; ¶Department of Medicine, University of Manitoba, Winnipeg, Canada; #Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada; **Department of Reproductive Health, Moi University, Eldoret, Kenya; ††Center for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya; ‡‡Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; and §§Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

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http://dx.doi.org/10.1097/QAI.0000000000001019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106226PMC
August 2016

Perceived Risk Among Human Immunodeficiency Virus Serodiscordant Couples in East Africa Taking Oral Pre-Exposure Prophylaxis.

Sex Transm Dis 2016 08;43(8):471-5

From the *Department of Epidemiology, †Department of Anthropology, ‡Department of Global Health, University of Washington, Seattle, WA; §Kenya Medical Research Institute; ‖Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya; ¶International Clinical Research Center, University of Washington, Seattle, WA; **Kabwohe Clinical Research Center, Kabwohe, Uganda; ††Department of Medicine, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/OLQ.0000000000000472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948939PMC
August 2016

Taking HIV Testing to Families: Designing a Family-Based Intervention to Facilitate HIV Testing, Disclosure, and Intergenerational Communication.

Front Public Health 2016 5;4:154. Epub 2016 Aug 5.

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.3389/fpubh.2016.00154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974258PMC
August 2016

Rapid Antiretroviral Therapy Initiation for Women in an HIV-1 Prevention Clinical Trial Experiencing Primary HIV-1 Infection during Pregnancy or Breastfeeding.

PLoS One 2015 15;10(10):e0140773. Epub 2015 Oct 15.

Department of Global Health, University of Washington, Seattle, WA, United States of America; Department of Medicine, University of Washington, Seattle, WA United States of America; Department of Epidemiology, University of Washington, Seattle, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140773PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607156PMC
July 2016

Seminal HIV-1 RNA Detection in Heterosexual African Men Initiating Antiretroviral Therapy.

J Infect Dis 2016 07 6;214(2):212-5. Epub 2016 Apr 6.

Department of Global Health Department of Epidemiology Department of Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1093/infdis/jiw131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918825PMC
July 2016

Regulatory T-Cell Activity But Not Conventional HIV-Specific T-Cell Responses Are Associated With Protection From HIV-1 Infection.

J Acquir Immune Defic Syndr 2016 Jun;72(2):119-28

*Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; Departments of †Global Health; ‡Epidemiology; §Medicine, University of Washington, Seattle, WA; ‖Statistical Center for HIV-1/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; ¶Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya; #Department of Obstetrics and Gynecology, University of Washington, Seattle, WA; **Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada; ††Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; and ‡‡Department of Pediatrics, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/QAI.0000000000000919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866890PMC
June 2016

Home testing and counselling to reduce HIV incidence in a generalised epidemic setting: a mathematical modelling analysis.

Lancet HIV 2016 06 11;3(6):e275-82. Epub 2016 May 11.

Department of Global Health, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-3018(16)30009-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927306PMC
June 2016

Comparison of subjective and objective adherence measures for preexposure prophylaxis against HIV infection among serodiscordant couples in East Africa.

AIDS 2016 Apr;30(7):1121-9

aDepartment of Medicine, Mbarara University of Science and Technology bEpiCentre/Médecins Sans Frontières cDepartment of Medical Laboratory Sciences, Mbarara University of Science and Technology, Mbarara, Uganda dDepartment of Infectious Diseases, University of Manitoba, Winnipeg, Canada eDepartment of Medicine, Division of Clinical Pharmacology, Johns Hopkins University, Baltimore, Maryland fDepartment of Global Health gDepartment of Medicine hDepartment of Epidemiology, University of Washington, Seattle, Washington iDepartment of Medicine, Harvard Medical School jDepartment of Global Health and Populations, Harvard T.H. Chan School of Public Health Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, USA. *Members of the "The Partners PrEP Ancillary Adherence Study Team" have been mentioned under Acknowledgements section.

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http://pdfs.journals.lww.com/aidsonline/9000/00000/Compariso
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAD.0000000000001024DOI Listing
April 2016

Reversibility of Glomerular Renal Function Decline in HIV-Uninfected Men and Women Discontinuing Emtricitabine-Tenofovir Disoproxil Fumarate Pre-Exposure Prophylaxis.

J Acquir Immune Defic Syndr 2016 Apr;71(4):374-80

*Department of Epidemiology, University of Washington, Seattle, WA;†Division of Disease Control, School of Public Health, Makerere University, Kampala, Uganda;‡Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY;Departments of §Global Health;‖Medicine, University of Washington, Seattle, WA;¶Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA;#Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya; and**Department of Medicine, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1097/QAI.0000000000000868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770857PMC
April 2016

Effect of Condom Use on Per-act HSV-2 Transmission Risk in HIV-1, HSV-2-discordant Couples.

Clin Infect Dis 2016 Feb 17;62(4):456-61. Epub 2015 Nov 17.

Department of Laboratory Medicine Department of Epidemiology, University of Washington, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center Department of Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1093/cid/civ908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725379PMC
February 2016

Preexposure prophylaxis-selected drug resistance decays rapidly after drug cessation.

AIDS 2016 01;30(1):31-5

aDivision of Human Biology, Fred Hutchinson Cancer Research CenterbDepartment of Global HealthcDepartment of MedicinedDepartment of Epidemiology, University of WashingtoneDivision of Public Health SciencesfVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WashingtongDepartment of MedicinehDepartment of Pharmacology and Molecular SciencesiDepartment of EpidemiologyjDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland, USAkKenyatta National Hospital, University of Nairobi, Kenya.

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http://dx.doi.org/10.1097/QAD.0000000000000915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704103PMC
January 2016

Effectiveness of hormonal contraception in HIV-infected women using antiretroviral therapy.

AIDS 2015 Nov;29(17):2353-9

aDepartment of Epidemiology bDepartment of Global Health cDepartment of Medicine, University of Washington, Seattle, Washington, USA dDepartment of Obstetrics & Gynaecology, University of Nairobi eSexual, Reproductive, Adolescent and Child Health Research Program, Kenya Medical Research Institute, Nairobi, Kenya fFHI 360, Contraceptive Technology Innovation Department, Durham, North Carolina gDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA hDepartment of Reproductive Health, Moi University, Eldoret, Kenya iWits Reproductive Health and HIV Institute (WRHI), University of the Witwatersrand, Johannesburg, South Africa jCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAD.0000000000000827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748843PMC
November 2015