Publications by authors named "Cong-Yi Wang"

100Publications

Correction: IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages.

Cell Death Differ 2021 Jan 5. Epub 2021 Jan 5.

The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Key Cite of National Clinical Research Center for Respiratory Disease, Wuhan Clinical Medical Research Center for Chronic Airway Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, 1095 Jiefang Ave, Wuhan, 430030, China.

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January 2021

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program.

Sci Adv 2020 Dec 4. Epub 2020 Dec 4.

The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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December 2020

SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.

J Mol Med (Berl) 2020 Dec 7;98(12):1795-1807. Epub 2020 Nov 7.

The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.

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December 2020

IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages.

Cell Death Differ 2020 Nov 3. Epub 2020 Nov 3.

The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Pulmonary Diseases, Key Cite of National Clinical Research Center for Respiratory Disease, Wuhan Clinical Medical Research Center for Chronic Airway Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, 1095 Jiefang Ave, Wuhan, 430030, China.

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November 2020

Cigarette smoke extract stimulates bronchial epithelial cells to undergo a SUMOylation turnover.

BMC Pulm Med 2020 Oct 23;20(1):276. Epub 2020 Oct 23.

The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Caidian, 431000, China.

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October 2020

The role of hydrogen sulphide signalling in macrophage activation.

Immunology 2021 Jan 6;162(1):3-10. Epub 2020 Oct 6.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, China.

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January 2021

The AHR Signaling Attenuates Autoimmune Responses During the Development of Type 1 Diabetes.

Front Immunol 2020 7;11:1510. Epub 2020 Aug 7.

Center for Biomedical Research, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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August 2020

Analysis of 2019 novel coronavirus infection and clinical characteristics of outpatients: An epidemiological study from a fever clinic in Wuhan, China.

J Med Virol 2020 11 14;92(11):2758-2767. Epub 2020 Jul 14.

Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Wuhan, China.

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November 2020

Adult-onset type 1 diabetic patients with less severe clinical manifestation have less risk DR-DQ genotypes than childhood-onset patients.

Diabetes Metab Res Rev 2021 Jan 21;37(1):e3357. Epub 2020 Jun 21.

Department of Endocrinology and Metabolism, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

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January 2021

Obesity predisposes to the risk of higher mortality in young COVID-19 patients.

J Med Virol 2020 11 19;92(11):2536-2542. Epub 2020 Jun 19.

Department of Radiology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.

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November 2020

Correction to: CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling.

Cell Mol Life Sci 2020 Nov;77(21):4441-4447

Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

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November 2020

SUMOylation, a multifaceted regulatory mechanism in the pancreatic beta cells.

Semin Cell Dev Biol 2020 07 21;103:51-58. Epub 2020 Apr 21.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Wuhan, China. Electronic address:

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July 2020

Extracellular HMGB1 exacerbates autoimmune progression and recurrence of type 1 diabetes by impairing regulatory T cell stability.

Diabetologia 2020 05 19;63(5):987-1001. Epub 2020 Feb 19.

The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, Caidian, China.

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May 2020

Comparison of rigid versus foldable iris-fixed phakic intraocular lens implantation for high myopia: A systematic review and meta-analysis.

Medicine (Baltimore) 2020 Feb;99(6):e19030

Cataract Intraocular Lens Center of the Fourth Hospital in Xi'an, Shaanxi Province, China.

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February 2020

CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling.

Cell Mol Life Sci 2020 Nov 4;77(21):4379-4395. Epub 2020 Feb 4.

Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

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November 2020

The impact of tobacco smoking on physical activity and metabolism in mice.

Int J Mol Epidemiol Genet 2019 15;10(5):67-76. Epub 2019 Dec 15.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Avenue, Wuhan 430030, Hubei, China.

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December 2019

Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.

Cell Prolif 2020 Feb 14;53(2):e12742. Epub 2020 Jan 14.

Key Laboratory of Organ Transplantation, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Ministry of Education, The Center for Biomedical Research, Chinese Academy of Medical Sciences, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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February 2020

Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization.

Cell Death Dis 2019 11 26;10(12):892. Epub 2019 Nov 26.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences,Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.

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November 2019

Aging and stress induced β cell senescence and its implication in diabetes development.

Aging (Albany NY) 2019 11 13;11(21):9947-9959. Epub 2019 Nov 13.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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November 2019

Early outcomes of vision and objective visual quality analysis after cataract surgery with trifocal intraocular lens implantation.

Int J Ophthalmol 2019 18;12(10):1575-1581. Epub 2019 Oct 18.

Ophthalmology Department, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.

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October 2019

Ubc9 deficiency selectively impairs the functionality of common lymphoid progenitors (CLPs) during bone marrow hematopoiesis.

Mol Immunol 2019 10 20;114:314-322. Epub 2019 Aug 20.

The Center for Biomedical Research, the Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430030, China. Electronic address:

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October 2019

Loss of Jak2 protects cardiac allografts from chronic rejection by attenuating Th1 response along with increased regulatory T cells.

Am J Transl Res 2019 15;11(2):624-640. Epub 2019 Feb 15.

The Center for Biomedical Research, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.

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February 2019

Autophagy in regulatory T cells: A double-edged sword in disease settings.

Mol Immunol 2019 05 7;109:43-50. Epub 2019 Mar 7.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China. Electronic address:

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May 2019

Macrophages: friend or foe in idiopathic pulmonary fibrosis?

Respir Res 2018 Sep 6;19(1):170. Epub 2018 Sep 6.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, China.

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September 2018

Assessing the impact of cigarette smoking on β-cell function and risk for type 2 diabetes in a non-diabetic Chinese cohort.

Am J Transl Res 2018 15;10(7):2164-2174. Epub 2018 Jul 15.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Avenue, Wuhan 430030, China.

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July 2018

MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL.

Cancer Res 2018 04 12;78(7):1632-1642. Epub 2018 Jan 12.

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

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April 2018

Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function.

Diabetologia 2018 04 3;61(4):881-895. Epub 2018 Jan 3.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.

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April 2018

Small interfering RNA directed against microRNA-155 delivered by a lentiviral vector attenuates asthmatic features in a mouse model of allergic asthma.

Exp Ther Med 2017 Nov 1;14(5):4391-4396. Epub 2017 Sep 1.

Department of Respiratory and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.

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November 2017

Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression.

Mediators Inflamm 2017 19;2017:5706152. Epub 2017 Sep 19.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China.

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June 2018

Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.

Mol Med Rep 2017 Nov 8;16(5):6787-6793. Epub 2017 Sep 8.

Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Key Laboratory of The Ministry of Health, Key Laboratory of The Ministry of Education, Wuhan, Hubei 430030, P.R. China.

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November 2017

CCR2 dependent neutrophil activation and mobilization rely on TLR4-p38 axis during liver ischemia-reperfusion injury.

Am J Transl Res 2017 15;9(6):2878-2890. Epub 2017 Jun 15.

Department of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan 430022, Hubei, China.

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June 2017

HMGB1, an innate alarmin, plays a critical role in chronic inflammation of adipose tissue in obesity.

Mol Cell Endocrinol 2017 10 12;454:103-111. Epub 2017 Jun 12.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, 1095 Jiefang Ave., Wuhan, 430030, China. Electronic address:

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October 2017

Diffusional kurtosis imaging in evaluating the secondary change of corticospinal tract after unilateral cerebral infarction.

Am J Transl Res 2017 15;9(3):1426-1434. Epub 2017 Mar 15.

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

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March 2017

Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis.

Am J Transl Res 2017 15;9(2):722-735. Epub 2017 Feb 15.

Clinical and Molecular Immunology Research Center, Department of Immunology, Medical College of Yangtze University Jingzhou, Hubei, China.

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February 2017

Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophages.

J Allergy Clin Immunol 2017 Dec 24;140(6):1550-1561.e8. Epub 2017 Feb 24.

Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, Key Laboratory of Organ Transplantation, Ministry of Health, Wuhan, China; Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Key Cite of National Clinical Research Center for Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences & Technology, Wuhan, China. Electronic address:

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December 2017

Sumoylation Modulates the Susceptibility to Type 1 Diabetes.

Adv Exp Med Biol 2017 ;963:299-322

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, Key Laboratory of Organ Transplantation, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, China.

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September 2017

Loss of Mbd2 Protects Mice Against High-Fat Diet-Induced Obesity and Insulin Resistance by Regulating the Homeostasis of Energy Storage and Expenditure.

Diabetes 2016 11 23;65(11):3384-3395. Epub 2016 Aug 23.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Medical College Union Hospital, Huazhong University of Science and Technology, Wuhan, China

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November 2016

Rat adipose-derived stem cells express low level of α-Gal and are dependent on CD59 for protection from human xenoantibody and complement-mediated lysis.

Am J Transl Res 2016 15;8(5):2059-69. Epub 2016 May 15.

Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and TechnologyWuhan, China; Key Laboratory of Organ Transplantation, Ministry of EducationChina; Key Laboratory of Organ Transplantation, Ministry of Public HealthChina.

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June 2016

HMGB1 exacerbates bronchiolitis obliterans syndrome via RAGE/NF-κB/HPSE signaling to enhance latent TGF-β release from ECM.

Am J Transl Res 2016 15;8(5):1971-84. Epub 2016 May 15.

The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education, Key Laboratory of Organ Transplantation, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and TechnologyWuhan 430030, China; Department of Sponsored Program Administration, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and TechnologyWuhan 430030, China.

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June 2016

HLA Genetic Discrepancy Between Latent Autoimmune Diabetes in Adults and Type 1 Diabetes: LADA China Study No. 6.

J Clin Endocrinol Metab 2016 04 11;101(4):1693-700. Epub 2016 Feb 11.

Department of Metabolism and Endocrinology (S.L., J.L., Z.X., Y.X., P.Z., G.H., X.L., Y.L., C.-Y.W., Z.Z.), Second Xiangya Hospital and Diabetes Center, Institute of Metabolism and Endocrinology, Central South University, and Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan 410011, China; Pacific Northwest Diabetes Research Institute and University of Washington (W.A.H.), Seattle, Washington 98122; and The Center for Biomedical Research (C.-Y.W.), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

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April 2016

Assessing the efficacy and safety of combined DPP-4 inhibitor and insulin treatment in patients with type 2 diabetes: a meta-analysis.

Int J Clin Exp Pathol 2015 1;8(11):14141-50. Epub 2015 Nov 1.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1059 Jiefang Ave., Wuhan 430030, China.

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October 2016

AAL exacerbates pro-inflammatory response in macrophages by regulating Mincle/Syk/Card9 signaling along with the Nlrp3 inflammasome assembly.

Am J Transl Res 2015 15;7(10):1812-25. Epub 2015 Oct 15.

The Center for Biomedical Research, Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave., Wuhan 430030, China.

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December 2015

Aloperine Protects Mice against Ischemia-Reperfusion (IR)-Induced Renal Injury by Regulating PI3K/AKT/mTOR Signaling and AP-1 Activity.

Mol Med 2016 Mar 3;21(1):912-923. Epub 2015 Nov 3.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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March 2016

TIGIT negatively regulates inflammation by altering macrophage phenotype.

Immunobiology 2016 Jan 17;221(1):48-55. Epub 2015 Aug 17.

Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, China. Electronic address:

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January 2016

ANP/NPRA signaling preferentially mediates Th2 responses in favor of pathological processes during the course of acute allergic asthma.

Int J Clin Exp Med 2015 15;8(4):5121-8. Epub 2015 Apr 15.

Institute of Emergency Medicine and Rare Diseases, Central South University Changsha 410011, China ; Department of Emergency Medicine, The Second Xiangya Hospital, Central South University Changsha 410011, China ; The Center for Biomedical Research, Tongji Hospital, Huazhong University of Science and Technology Wuhan 430030, China.

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July 2015

Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages.

Dis Model Mech 2015 Jul 21;8(7):691-700. Epub 2015 Apr 21.

Department of Molecular Biology, Medical College of Yangtze University, 1 Nanhuan Road, Jingzhou, Hubei 434023, China The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College, No. 1 Xincheng Road, Dongguan 523808, China

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July 2015

BTLA associates with increased Foxp3 expression in CD4(+) T cells in dextran sulfate sodium-induced colitis.

Int J Clin Exp Pathol 2015 1;8(2):1259-69. Epub 2015 Feb 1.

Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College 1 Xincheng Road, Dongguan 523808, China ; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics 1 Xincheng Road, Dongguan 523808, China.

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March 2016

Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice.

J Immunol 2015 Jun 24;194(11):5261-71. Epub 2015 Apr 24.

Center for Biotechnology and Genomic Medicine, Georgia Regents University, Augusta, GA 30912;

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June 2015

Telmisartan protects 5/6 Nx rats against renal injury by enhancing nNOS-derived NO generation via regulation of PPARγ signaling.

Am J Transl Res 2014 11;6(5):517-27. Epub 2014 Oct 11.

Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.

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October 2014

BTLA exhibits immune memory for αβ T cells in patients with active pulmonary tuberculosis.

Am J Transl Res 2014 11;6(5):494-506. Epub 2014 Oct 11.

Department of Clinical Immunology, Institute of Clinical Laboratory Medicine, Guangdong Medical College No. 1 Xincheng Road, Dongguan 523808, China ; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics No. 1 Xincheng Road, Dongguan 523808, China.

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October 2014

Assessment of type 2 diabetes risk conferred by SNPs rs2241766 and rs1501299 in the ADIPOQ gene, a case/control study combined with meta-analyses.

Mol Cell Endocrinol 2014 Oct 15;396(1-2):1-9. Epub 2014 Aug 15.

The Center for Biomedical Research, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China; College of Medicine, Changjiang University, 55 Jianghan Road, Jingzhou, Hubei 434023, China. Electronic address:

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October 2014

Sumoylation modulates oxidative stress relevant to the viability and functionality of pancreatic beta cells.

Am J Transl Res 2014 18;6(4):353-60. Epub 2014 Jul 18.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave., Wuhan 430030, China ; Department of Immunology, Medical College of Yangtze University 55 Jianghan Road, Jingzhou, Hubei 434023, China ; Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College Dongguan 523808, China.

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July 2014

Three-year follow-up results for non-surgical root canal therapy of idiopathic external root resorption on a maxillary canine with MTA: a case report.

Int J Clin Exp Pathol 2014 15;7(6):3338-46. Epub 2014 May 15.

Department of Restorative Dentistry, Indiana University School of Dentistry Indianapolis, IN 46202, USA.

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May 2015

Comparative analysis of arterial spin labeling and dynamic susceptibility contrast perfusion imaging for quantitative perfusion measurements of brain tumors.

Int J Clin Exp Pathol 2014 15;7(6):2790-9. Epub 2014 May 15.

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave. Wuhan 430030, China.

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May 2015

Clinical and genetic characteristics for the Urofacial Syndrome (UFS).

Int J Clin Exp Pathol 2014 15;7(5):1842-8. Epub 2014 Apr 15.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave., Wuhan 430030, China.

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February 2015

MBD2 regulates TH17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis.

J Autoimmun 2014 Sep 14;53:95-104. Epub 2014 Jun 14.

The Center for Biomedical Research, Tongji Hospital, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan 430030, China. Electronic address:

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September 2014

Risk factors for central lymph node metastasis of patients with papillary thyroid microcarcinoma: a meta-analysis.

Int J Clin Exp Pathol 2014 15;7(3):932-7. Epub 2014 Feb 15.

Department of General Surgery, Affiliated Union Hospital, Tongji Medical College Wuhan, China.

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December 2014

MRI and ultrasonography detection of cervical lymph node metastases in differentiated thyroid carcinoma before reoperation.

Am J Transl Res 2014 15;6(2):147-54. Epub 2014 Jan 15.

Department of General Surgery, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

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February 2014

Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.

PLoS One 2014 8;9(1):e84485. Epub 2014 Jan 8.

Department of Orthopedic Surgery and BioMedical Engineering, Campbell-Clinic, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.

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September 2014

Assessing the optimal dose for Cetrorelix in Chinese women undergoing ovarian stimulation during the course of IVF-ET treatment.

Am J Transl Res 2013 1;6(1):78-84. Epub 2013 Dec 1.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, 430030, China ; Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College Dongguan 523808, China.

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December 2013

Blockade of dopamine D1-like receptor signalling protects mice against OVA-induced acute asthma by inhibiting B-cell activating transcription factor signalling and Th17 function.

FEBS J 2013 Dec 25;280(23):6262-73. Epub 2013 Oct 25.

Department of Respiratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, China; Department of Geriatrics, The Second Xiangya Hospital, Central South University, Changsha, China.

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December 2013

Comparison of the GnRH agonist and antagonist protocol on the same patients in assisted reproduction during controlled ovarian stimulation cycles.

Int J Clin Exp Pathol 2013 15;6(9):1903-10. Epub 2013 Aug 15.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China ; Department of Obstetric and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.

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April 2014

Assessing the role of IL-35 in colorectal cancer progression and prognosis.

Int J Clin Exp Pathol 2013 15;6(9):1806-16. Epub 2013 Aug 15.

Department of Clinical Immunology, Institute of Laboratory Medicine, Guangdong Medical College Dongguan, China, 523808 ; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics Dongguan 523808, China.

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April 2014

A simplified two-stitch sleeve technique for arterial anastomosis of cervical heterotopic cardiac transplantation in mice.

Am J Transl Res 2013 15;5(5):521-9. Epub 2013 Aug 15.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China ; Key Laboratory of Organ Transplantation, Ministry of Education, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China ; Department of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.

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August 2013

Comparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase.

BMC Immunol 2013 Jun 17;14:25. Epub 2013 Jun 17.

Intensive Care Unit, Diabetes Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.

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June 2013

Loss of Jak2 impairs endothelial function by attenuating Raf-1/MEK1/Sp-1 signaling along with altered eNOS activities.

Am J Pathol 2013 Aug 6;183(2):617-25. Epub 2013 Jun 6.

Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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August 2013

SUMO1 regulates endothelial function by modulating the overall signals in favor of angiogenesis and homeostatic responses.

Am J Transl Res 2013 24;5(4):427-40. Epub 2013 May 24.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave, Wuhan 430030, China.

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June 2013

TJ0711, a novel vasodilatory β-blocker, protects SHR rats against hypertension induced renal injury.

Am J Transl Res 2013 19;5(3):279-90. Epub 2013 Apr 19.

Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.

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May 2013

DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes.

J Autoimmun 2013 Mar 11;41:50-9. Epub 2013 Mar 11.

Diabetes Center, 2nd Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, 139 Renmin Middle Rd, Changsha, Hunan 410011, China.

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March 2013

Comparative analysis of dendritic cell numbers and subsets between smoking and control subjects in the peripheral blood.

Int J Clin Exp Pathol 2013 15;6(2):290-6. Epub 2013 Jan 15.

Division of Respiratory Medicine, Renmin Hospital, Wuhan University Wuhan, China.

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July 2013

The significance of antral follicle size prior to stimulation in predicting ovarian response in a multiple dose GnRH antagonist protocol.

Int J Clin Exp Pathol 2013 15;6(2):258-66. Epub 2013 Jan 15.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Ave, Wuhan 430030, China.

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July 2013

Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein.

BMC Biotechnol 2012 Nov 28;12:91. Epub 2012 Nov 28.

Department of Pathology, Nanjing Drum Tower Hospital affiliated Nanjing University Medical School, Nanjing, People's Republic of China.

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November 2012

The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis.

Int J Clin Exp Pathol 2012 1;5(8):726-38. Epub 2012 Oct 1.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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April 2013

Plasmacytoid urothelial carcinoma of the urinary bladder: a clinical pathological study and literature review.

Int J Clin Exp Pathol 2012 29;5(6):601-8. Epub 2012 Jul 29.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, PR China.

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January 2013

Loss of dicer exacerbates cyclophosphamide-induced bladder overactivity by enhancing purinergic signaling.

Am J Pathol 2012 Sep 13;181(3):937-46. Epub 2012 Jul 13.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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September 2012

The role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes.

Exp Diabetes Res 2012 14;2012:238980. Epub 2012 Feb 14.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China.

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July 2012

FUT2 nonfunctional variant: a "missing link" between genes and environment in type 1 diabetes?

Diabetes 2011 Nov;60(11):2685-7

Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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November 2011

Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population.

Acta Pharmacol Sin 2011 Nov 3;32(11):1357-63. Epub 2011 Oct 3.

Institute of Hypertension, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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November 2011

Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury.

Circulation 2011 Jun 13;123(25):2964-74. Epub 2011 Jun 13.

Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, China.

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June 2011

SUMO1 negatively regulates reactive oxygen species production from NADPH oxidases.

Arterioscler Thromb Vasc Biol 2011 Jul 28;31(7):1634-42. Epub 2011 Apr 28.

Vascular Biology Center, Medical College of Georgia, Augusta, GA 30912, USA.

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July 2011

Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.

Am J Physiol Cell Physiol 2011 Mar 15;300(3):C447-55. Epub 2010 Dec 15.

Dept. of Cellular Biology and Anatomy, Medical College of Georgia, 1459 Laney Walker Blvd., Augusta, GA 30912, USA.

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March 2011

Intratumoral convergence of the TCR repertoires of effector and Foxp3+ CD4+ T cells.

PLoS One 2010 Oct 26;5(10):e13623. Epub 2010 Oct 26.

Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, Georgia, United States of America.

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October 2010

High-mobility group box 1 promotes early acute allograft rejection by enhancing IL-6-dependent Th17 alloreactive response.

Lab Invest 2011 Jan 16;91(1):43-53. Epub 2010 Aug 16.

Laboratory of Transplantation, Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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January 2011

Neutralization of the extracellular HMGB1 released by ischaemic damaged renal cells protects against renal ischaemia-reperfusion injury.

Nephrol Dial Transplant 2011 Feb 2;26(2):469-78. Epub 2010 Aug 2.

Institute of Organ Transplantation, Tongji Hospital, Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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February 2011

PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.

J Am Soc Nephrol 2010 Jul 15;21(7):1115-24. Epub 2010 Apr 15.

Department of Cellular Biology and Anatomy, Medical College of Georgia and Charlie Norwood Veterans' Affairs Medical Center, Augusta, Georgia 30912, USA.

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July 2010

Ectopic B7-H4-Ig expression attenuates concanavalin A-induced hepatic injury.

Clin Immunol 2010 Jul 25;136(1):30-41. Epub 2010 Mar 25.

Department of Clinical Immunology, Guangdong Medical College, Dongguan, Guangdong, 523808, People's Republic of China.

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July 2010

Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock.

PLoS One 2010 Mar 9;5(3):e9593. Epub 2010 Mar 9.

Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

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March 2010

9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population.

Circ Cardiovasc Genet 2009 Aug 28;2(4):338-46. Epub 2009 May 28.

Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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August 2009

HMGB1, an innate alarmin, in the pathogenesis of type 1 diabetes.

Int J Clin Exp Pathol 2009 Sep 8;3(1):24-38. Epub 2009 Sep 8.

The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Hua-Zhong University of Science and Technology, Wuhan, China.

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September 2009