Colum P Walsh

Colum P Walsh

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Colum P Walsh

Colum P Walsh

Publications by authors named "Colum P Walsh"

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Maternal folate nutrition and offspring health: evidence and current controversies.

Proc Nutr Soc 2018 Dec 26:1-13. Epub 2018 Dec 26.

Nutrition Innovation Centre for Food and Health,School of Biomedical Sciences,Ulster University,Coleraine,Northern Ireland BT52 1SA.

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http://dx.doi.org/10.1017/S0029665118002689DOI Listing
December 2018

Imprint stability and plasticity during development.

Reproduction 2018 08 9;156(2):R43-R55. Epub 2018 May 9.

Genomic Medicine Research GroupSchool of Biomedical Sciences, Ulster University, Northern Ireland, UK

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http://dx.doi.org/10.1530/REP-18-0051DOI Listing
August 2018

Comparison of DNMT1 inhibitors by methylome profiling identifies unique signature of 5-aza-2'deoxycytidine.

Epigenomics 2018 08 2;10(8):1085-1101. Epub 2018 Aug 2.

Genomic Medicine Research Group, Centre for Molecular Biosciences, Biomedical Sciences Research Institute, Ulster University, Coleraine, BT52 1SA, UK.

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http://dx.doi.org/10.2217/epi-2017-0171DOI Listing
August 2018

Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy: epigenetic analysis from a randomized controlled trial.

Am J Clin Nutr 2018 04;107(4):566-575

Nutrition Innovation Centre for Food and Health and Genomic Medicine Group, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/nqx069DOI Listing
April 2018

Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression.

Epigenetics Chromatin 2018 03 29;11(1):12. Epub 2018 Mar 29.

Genomic Medicine Research Group, Centre for Molecular Biosciences, School of Biomedical Sciences, Ulster University, Cromore Road, Coleraine, BT52 1SA, UK.

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https://epigeneticsandchromatin.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/s13072-018-0182-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875016PMC
March 2018

Regulation of miR-200c and miR-141 by Methylation in Prostate Cancer.

Prostate 2016 09 16;76(13):1146-59. Epub 2016 May 16.

Biomedical Sciences Research Institute, University of Ulster, Coleraine, UK.

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http://dx.doi.org/10.1002/pros.23201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082568PMC
September 2016

The interplay between DNA methylation, folate and neurocognitive development.

Epigenomics 2016 06 20;8(6):863-79. Epub 2016 Jun 20.

EpiFASSTT study, Biomedical Sciences, Ulster University, Coleraine, UK.

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https://www.futuremedicine.com/doi/10.2217/epi-2016-0003
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http://dx.doi.org/10.2217/epi-2016-0003DOI Listing
June 2016

miR-24 regulates CDKN1B/p27 expression in prostate cancer.

Prostate 2016 May 5;76(7):637-48. Epub 2016 Feb 5.

Biomedical Sciences Research Institute, University of Ulster, Coleraine, Derry, United Kingdom.

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http://dx.doi.org/10.1002/pros.23156DOI Listing
May 2016

Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements.

PLoS One 2014 20;9(2):e88385. Epub 2014 Feb 20.

Transcriptional Regulation and Epigenetics Research Group, School of Biomedical Sciences, University of Ulster, Coleraine, North Ireland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930535PMC
January 2015

5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels.

Genomics 2014 Nov 29;104(5):383-92. Epub 2014 Aug 29.

Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2014.08.013DOI Listing
November 2014

Enzymatic DNA oxidation: mechanisms and biological significance.

BMB Rep 2014 Nov;47(11):609-18

Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281339PMC
http://dx.doi.org/10.5483/bmbrep.2014.47.11.223DOI Listing
November 2014

Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote.

Cell Stem Cell 2014 Oct 15;15(4):447-459. Epub 2014 Sep 15.

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.08.003DOI Listing
October 2014

siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy.

Invest Ophthalmol Vis Sci 2014 May 6;55(5):3352-60. Epub 2014 May 6.

School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, United Kingdom Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry & Nursing, University of Dundee, Dundee, Scotland, United Kingdom Centre for Regenerative Medicine, Stefano Ferrari, University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1167/iovs.13-12957DOI Listing
May 2014

Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes.

Development 2014 Mar 12;141(6):1313-23. Epub 2014 Feb 12.

Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK.

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http://dx.doi.org/10.1242/dev.104646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943183PMC
March 2014

DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Hum Mol Genet 2011 Aug 2;20(16):3241-55. Epub 2011 Jun 2.

Transcriptional Regulation and Epigenetics Group, Centre for Molecular Biosciences, University of Ulster, Coleraine BT52 1SA, UK.

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http://dx.doi.org/10.1093/hmg/ddr236DOI Listing
August 2011

DNA methylation plays an important role in promoter choice and protein production at the mouse Dnmt3L locus.

Dev Biol 2011 Aug 30;356(2):411-20. Epub 2011 May 30.

Transcriptional Regulation and Epigenetics Research Group, Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK.

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http://dx.doi.org/10.1016/j.ydbio.2011.05.665DOI Listing
August 2011

DNA methyltransferase loading, but not de novo methylation, is an oocyte-autonomous process stimulated by SCF signalling.

Dev Biol 2008 Sep 25;321(1):238-50. Epub 2008 Jun 25.

Stem Cells and Epigenetics Research Group, Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, Northern Ireland, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S001216060801015
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http://dx.doi.org/10.1016/j.ydbio.2008.06.024DOI Listing
September 2008

DNA methylation reprogramming in the germ line.

Epigenetics 2008 Jan-Feb;3(1):5-13. Epub 2008 Jan 9.

Stem Cells and Epigenetics Research Group, School of Biomedical Sciences, Centre for Molecular Bioscience, University of Ulster, Coleraine, North Ireland, UK.

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http://dx.doi.org/10.4161/epi.3.1.5553DOI Listing
June 2008

DNA methylation reprogramming in the germ line.

Adv Exp Med Biol 2008 ;626:1-15

Stem Cells and Epigenetics Research Group, School of Biomedical Sciences, Centre for Molecular Bioscience, University of Ulster, Coleraine, Northern Ireland, UK.

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http://dx.doi.org/10.1007/978-0-387-77576-0_1DOI Listing
April 2008

Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.

Nucleic Acids Res 2007 14;35(2):390-400. Epub 2006 Dec 14.

The State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1093/nar/gkl1052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802599PMC
March 2007

DNA methyltransferase expression in the mouse germ line during periods of de novo methylation.

Dev Dyn 2005 Apr;232(4):992-1002

Cancer and Ageing Research Group, School of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom.

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http://dx.doi.org/10.1002/dvdy.20288DOI Listing
April 2005

Timing of establishment of paternal methylation imprints in the mouse.

Genomics 2004 Dec;84(6):952-60

Laboratory for Molecular Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1016/j.ygeno.2004.08.012DOI Listing
December 2004

Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation.

Mol Cancer 2002 Jul 11;1. Epub 2002 Jul 11.

Cancer and Ageing Research Group, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC119368PMC
July 2002