Publications by authors named "Colm Morrissey"

100Publications

FOXA2 promotes prostate cancer growth in the bone.

Am J Transl Res 2020 15;12(9):5619-5629. Epub 2020 Sep 15.

Department of Biochemistry and Molecular Biology, LSU Health Shreveport, LA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540102PMC
September 2020

EGFR as a stable marker of prostate cancer dissemination to bones.

Br J Cancer 2020 Sep 9. Epub 2020 Sep 9.

Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland.

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http://dx.doi.org/10.1038/s41416-020-01052-8DOI Listing
September 2020

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress.

Cell Rep 2020 May;31(8):107669

Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA; Department of Urology, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453577PMC
May 2020

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4.

Neoplasia 2020 06 11;22(6):253-262. Epub 2020 May 11.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA; Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218227PMC
June 2020

Neutrophils are mediators of metastatic prostate cancer progression in bone.

Cancer Immunol Immunother 2020 Jun 29;69(6):1113-1130. Epub 2020 Feb 29.

Department of Pathology and Microbiology, University of Nebraska Medical Center, 985900 Nebraska Med Center, Omaha, NE, 68192, USA.

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http://dx.doi.org/10.1007/s00262-020-02527-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230043PMC
June 2020

Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion.

Prostate 2019 09 2;79(13):1530-1542. Epub 2019 Aug 2.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1002/pros.23874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783279PMC
September 2019

Distinct expression patterns of SULT2B1b in human prostate epithelium.

Prostate 2019 08 18;79(11):1256-1266. Epub 2019 Jun 18.

Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana.

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http://dx.doi.org/10.1002/pros.23829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064034PMC
August 2019

ALDH1-positive intratumoral stromal cells indicate differentiated epithelial-like phenotype and good prognosis in prostate cancer.

Transl Res 2019 01 12;203:49-56. Epub 2018 Sep 12.

Department of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Laboratory of Cell Biology, Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19315244183014
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http://dx.doi.org/10.1016/j.trsl.2018.08.007DOI Listing
January 2019

Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer.

Mol Cancer Res 2018 08 14;16(8):1319-1331. Epub 2018 May 14.

The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369592PMC
August 2018

Plasma Fatty Acids as Surrogate for Prostate Levels.

Nutr Cancer 2018 01 21;70(1):45-50. Epub 2017 Dec 21.

a Fred Hutchinson Cancer Research Center, Cancer Prevention Program , Seattle , Washington , USA.

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http://dx.doi.org/10.1080/01635581.2018.1412479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188702PMC
January 2018

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.

Cancer Cell 2017 10;32(4):474-489.e6

Department of Medicine, University of Washington, Seattle, WA, USA; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Mailstop D4-100, 1100 Fairview Avenue N, Seattle, WA 98109-1024, USA; Department of Urology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA; Department of Pathology, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750052PMC
October 2017

TWIST1-WDR5- Regulates Chromatin to Facilitate Prostate Cancer Metastasis.

Cancer Res 2017 06 8;77(12):3181-3193. Epub 2017 May 8.

Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489316PMC
June 2017

Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells.

J Cell Biochem 2017 05 5;118(5):1038-1049. Epub 2017 Jan 5.

The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724.

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http://dx.doi.org/10.1002/jcb.25673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553695PMC
May 2017

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.

N Engl J Med 2016 Aug 6;375(5):443-53. Epub 2016 Jul 6.

From the University of Washington (C.C.P., M. Beightol, C.M., B.N., H.H.C., B.M., T.W., S. Casadei, P.S.N.) and Fred Hutchinson Cancer Research Center (N.D.S., R.G., P.S.N.) - both in Seattle; the Institute of Cancer Research and Royal Marsden Hospital, London (J.M., S. Carreira, R.E., J.B.); Memorial Sloan Kettering Cancer Center (M.F.W., W.A., M. Berger, L.Z., A.Z., J. Vijai, H.I.S., C.S., N.S., P.W.K., D.S., M.R., K.O.), Weill Cornell Medical College (H.B., O.E., M.A.R.), and the Prostate Cancer Clinical Trials Consortium (J. Vinson, J.F.) - all in New York; the University of Michigan, Ann Arbor (D.R., R.L., M.H., A.C.); Howard Hughes Medical Institute, Chevy Chase, MD (A.C., C.S.); and Dana-Farber Cancer Institute, Boston (A.G., L.G., M.-E.T., S.A., G.C.H., E.M.V.A.).

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http://dx.doi.org/10.1056/NEJMoa1603144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986616PMC
August 2016

Expression of STAT3 in Prostate Cancer Metastases.

Eur Urol 2017 03 22;71(3):313-316. Epub 2016 Jun 22.

Department of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden; Department of Urology, Skåne University Hospital, Lund University, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624794PMC
March 2017

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.

Mol Cancer Res 2016 Apr 11;14(4):374-84. Epub 2016 Jan 11.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Pathology, University of Washington, Seattle, Washington. Department of Urology, University of Washington, Seattle, Washington. Department of Medicine, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582956PMC
April 2016

Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.

Proc Natl Acad Sci U S A 2016 Jan 30;113(2):E172-81. Epub 2015 Nov 30.

Molecular Biology Institute, University of California, Los Angeles, CA 90095; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095; Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095; David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1521674112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720329PMC
January 2016

High-Resolution Genomic Profiling of Disseminated Tumor Cells in Prostate Cancer.

J Mol Diagn 2016 Jan 20;18(1):131-43. Epub 2015 Nov 20.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Urology, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2015.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715223PMC
January 2016

The biology and clinical implications of prostate cancer dormancy and metastasis.

J Mol Med (Berl) 2016 Mar 21;94(3):259-65. Epub 2015 Oct 21.

Department of Urology, University of Washington, 1959 Pacific Street NE, Box 356510, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1007/s00109-015-1353-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803572PMC
March 2016

Relationship between serum response factor and androgen receptor in prostate cancer.

Prostate 2015 Nov 7;75(15):1704-17. Epub 2015 Aug 7.

UCDSchool of Medicine and Medical Science, Conway Institute of Biomolecular Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.23051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579008PMC
November 2015

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

Cancer Cell 2015 Jun;27(6):797-808

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Pathology, University of Washington, Seattle, WA 98195, USA; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461839PMC
June 2015

A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells.

Cancer Immunol Res 2015 Oct 5;3(10):1175-84. Epub 2015 Jun 5.

Department of Pathology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596748PMC
October 2015

Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment.

Bone 2015 Sep 5;78:81-6. Epub 2015 May 5.

Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA; The Atlanta VA Medical Center, Decatur, GA 30033, USA; Emory University Winship Cancer Institute, Atlanta, GA 30322, USA; Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.04.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466124PMC
September 2015

Chemotherapeutic effects on circulating tumor cells in bladder cancer.

Int J Urol 2015 Jun 31;22(6):612-3. Epub 2015 Mar 31.

Department of Urology, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1111/iju.12758DOI Listing
June 2015

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes.

Nat Commun 2015 Jan 30;6:6170. Epub 2015 Jan 30.

1] Division of Hematology and Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA [2] Department of Otolaryngology, Mount Sinai School of Medicine, New York, New York 10029, USA [3] Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York 10029, USA [4] Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/ncomms7170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313575PMC
January 2015

Quantitative and stoichiometric analysis of the microRNA content of exosomes.

Proc Natl Acad Sci U S A 2014 Oct 29;111(41):14888-93. Epub 2014 Sep 29.

Divisions of Human Biology, Departments of Internal Medicine and Clinical Research, Biomedical Engineering, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; Biointerfaces Institute, and Center for Computational Medicine, University of Michigan, Ann Arbor, MI 48109; and

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http://dx.doi.org/10.1073/pnas.1408301111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205618PMC
October 2014

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.

Cancer Discov 2014 Nov 13;4(11):1310-25. Epub 2014 Aug 13.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Pathology, University of Washington, Seattle, Washington. Department of Urology, University of Washington, Seattle, Washington. Department of Medicine, University of Washington, Seattle, Washington.

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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-1010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409786PMC
November 2014

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases.

Prostate 2014 Feb;74(3):306-13

OncoMark Ltd, Nova UCD, University College Dublin, Belfield, Dublin 4, Ireland; Department of Pathology, RCSI Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland.

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http://doi.wiley.com/10.1002/pros.22752
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http://dx.doi.org/10.1002/pros.22752DOI Listing
February 2014

Prostate cancer derived prostatic acid phosphatase promotes an osteoblastic response in the bone microenvironment.

Clin Exp Metastasis 2014 Feb 17;31(2):247-56. Epub 2013 Nov 17.

Genitourinary Cancer Research Laboratory, Department of Urology, University of Washington, Box 356510, Seattle, WA, 98195, USA.

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http://link.springer.com/10.1007/s10585-013-9625-2
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http://dx.doi.org/10.1007/s10585-013-9625-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946934PMC
February 2014

Dormancy in solid tumors: implications for prostate cancer.

Cancer Metastasis Rev 2013 Dec;32(3-4):501-9

Department of Urology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s10555-013-9422-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796576PMC
December 2013

Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression.

Mol Cell Proteomics 2013 Jun 26;12(6):1589-601. Epub 2013 Feb 26.

Department of Pathology and Laboratory Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5T 3L9.

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http://dx.doi.org/10.1074/mcp.M112.023887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675816PMC
June 2013

Circulating tumor cells as a marker of response: implications for determining treatment efficacy and evaluating new agents.

Curr Opin Urol 2012 May;22(3):190-6

Department of Urology, University of Washington Medical Center, Seattle, Washington, USA.

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https://insights.ovid.com/crossref?an=00042307-201205000-000
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http://dx.doi.org/10.1097/MOU.0b013e3283519b58DOI Listing
May 2012

Human prostate cancer harbors the stem cell properties of bone marrow mesenchymal stem cells.

Clin Cancer Res 2011 Apr 25;17(8):2159-69. Epub 2011 Feb 25.

Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085118PMC
April 2011

The effect of green tea on oxidative damage and tumour formation in Lobund-Wistar rats.

Eur J Cancer Prev 2008 Nov;17(6):489-501

Centre for Colorectal Disease, Education and Research Centre, St Vincents University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/CEJ.0b013e3282f0c04eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214214PMC
November 2008

Histopathological assessment of prostate cancer bone osteoblastic metastases.

J Urol 2008 Sep 18;180(3):1154-60. Epub 2008 Jul 18.

Department of Pathology, University of Washington and Research Service, Seattle, Washington, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002253470801220
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http://dx.doi.org/10.1016/j.juro.2008.04.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992811PMC
September 2008

Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms.

Prostate 2007 Nov;67(15):1641-53

UCD School of Medicine and Medical Sciences, Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.20653DOI Listing
November 2007

Alterations in the expression of inhibitors of apoptosis during differentiation of prostate epithelial cells.

BJU Int 2007 Aug;100(2):445-9

UCD School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin and Dublin Molecular Medicine Centre, Dublin, Ireland.

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http://dx.doi.org/10.1111/j.1464-410X.2007.06932.xDOI Listing
August 2007

Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.

Int J Urol 2007 Jun;14(6):545-51

Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, Dublin Molecular Medicine Centre, University College Dublin, Dublin, Ireland.

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http://doi.wiley.com/10.1111/j.1442-2042.2007.01774.x
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http://dx.doi.org/10.1111/j.1442-2042.2007.01774.xDOI Listing
June 2007

The role of tumor microenvironment in prostate cancer bone metastasis.

J Cell Biochem 2007 Jul;101(4):873-86

Department of Urology, University of Washington, Seattle, WA 98195, USA.

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http://doi.wiley.com/10.1002/jcb.21214
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http://dx.doi.org/10.1002/jcb.21214DOI Listing
July 2007