Publications by authors named "Colin R Goding"

88Publications

Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development".

Handb Exp Pharmacol 2020 Jun 17. Epub 2020 Jun 17.

Skin Biology and Melanoma Lab, Department of Clinical Chemistry and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1007/164_2020_369DOI Listing
June 2020

A Reply to ''Evidence that STK19 Is Not an NRAS-Dependent Melanoma Driver".

Cell 2020 Jun;181(6):1406-1409.e2

Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.029DOI Listing
June 2020

The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor.

PLoS Genet 2019 12 27;15(12):e1008501. Epub 2019 Dec 27.

Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1008501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934268PMC
December 2019

ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation.

Pigment Cell Melanoma Res 2020 01 28;33(1):112-118. Epub 2019 Oct 28.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/pcmr.12830DOI Listing
January 2020

Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities.

Genes Dev 2019 10;33(19-20):1295-1318

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1101/gad.329771.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771388PMC
October 2019

MITF controls the TCA cycle to modulate the melanoma hypoxia response.

Pigment Cell Melanoma Res 2019 11 8;32(6):792-808. Epub 2019 Jul 8.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/pcmr.12802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777998PMC
November 2019

MITF-the first 25 years.

Genes Dev 2019 08 23;33(15-16):983-1007. Epub 2019 May 23.

National Institute of Neurological Disorders and Stroke, National Institutes of Heath, Bethesda, Maryland 20824, USA.

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.324657.119
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http://dx.doi.org/10.1101/gad.324657.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672050PMC
August 2019

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.

Nat Commun 2019 02 20;10(1):877. Epub 2019 Feb 20.

Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, 02118, USA.

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http://dx.doi.org/10.1038/s41467-019-08691-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382811PMC
February 2019

Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis.

Cell 2019 02 31;176(5):1113-1127.e16. Epub 2019 Jan 31.

Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193003
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http://dx.doi.org/10.1016/j.cell.2019.01.002DOI Listing
February 2019

Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming.

Cell Metab 2019 02 20;29(2):254-267. Epub 2018 Dec 20.

Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365217PMC
February 2019

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Proc Natl Acad Sci U S A 2018 09 27;115(37):E8668-E8677. Epub 2018 Aug 27.

Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Headington, OX3 7DQ Oxford, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1810498115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140509PMC
September 2018

A TFEB nuclear export signal integrates amino acid supply and glucose availability.

Nat Commun 2018 07 11;9(1):2685. Epub 2018 Jul 11.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1038/s41467-018-04849-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041281PMC
July 2018

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy.

Oncogene 2018 09 22;37(36):4941-4954. Epub 2018 May 22.

Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, 210028, Nanjing, Jiangsu, China.

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http://www.nature.com/articles/s41388-018-0314-0
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http://dx.doi.org/10.1038/s41388-018-0314-0DOI Listing
September 2018

Cell and molecular biology: a new section joins the fight against cancer.

Authors:
Colin R Goding

Br J Cancer 2018 01 12;118(1):1-2. Epub 2017 Dec 12.

Ludwig Institute for Cancer Research, University of Oxford, Nuffield Department of Clinical Medicine, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1038/bjc.2017.443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765237PMC
January 2018

Macrophage Cytoplasmic Transfer in Melanoma Invasion.

Dev Cell 2017 12;43(5):543-544

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.11.012DOI Listing
December 2017

Palmitoylation-dependent activation of MC1R prevents melanomagenesis.

Nature 2017 09 6;549(7672):399-403. Epub 2017 Sep 6.

Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1038/nature23887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902815PMC
September 2017

KIT Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma.

Mol Cancer Res 2017 09 5;15(9):1265-1274. Epub 2017 Jun 5.

Division of Translational Cancer Research, Lund Stem Cell Center, Lund University, Medicon Village and Department of Oncology, Skåne University Hospital, Lund, Sweden.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-17-0149DOI Listing
September 2017

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

EBioMedicine 2017 Feb 16;16:63-75. Epub 2017 Jan 16.

School of Biomedical Sciences, Institute of Health and Biomedical Innovation at the Translational Research Institute, Queensland University of Technology, Woolloongabba, QLD 4102, Australia; Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, QLD 4102, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474438PMC
February 2017

Targeting the lncRNA SAMMSON Reveals Metabolic Vulnerability in Melanoma.

Authors:
Colin R Goding

Cancer Cell 2016 05;29(5):619-621

Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Headington, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.04.010DOI Listing
May 2016

The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.

Sci Signal 2015 Sep 1;8(392):ra87. Epub 2015 Sep 1.

Department of Pharmacology and Experimental Therapeutics, Boston University Cancer Center, Boston University School of Medicine, Boston, MA 02118, USA. Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 20032, P. R. China.

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http://dx.doi.org/10.1126/scisignal.aab1995DOI Listing
September 2015

MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma.

Pigment Cell Melanoma Res 2015 Nov;28(6):736-40

Skin Cancer Unit of the Dermatology Department, Medical Faculty, West German Cancer Center, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/pcmr.12414DOI Listing
November 2015

Afamelanotide for Erythropoietic Protoporphyria.

N Engl J Med 2015 Jul;373(1):48-59

The Department of Internal Medicine, Center of Lysosomal and Metabolic Diseases, Erasmus Medical Center, Rotterdam (J.G.L., F.P.J.K., E.J.G.S., F.W.M.R., J.H.P.W.), and the Department of Dermatology, Maastricht University Medical Center, Maastricht (J.F.) - both in the Netherlands; the Departments of Genetics and Genomic Sciences (M.B., H.N., R.J.D.) and Dermatology (M.L.), Icahn School of Medicine at Mount Sinai, New York; the Departments of Preventive Medicine and Community Health, and Internal Medicine and the Institute for Translational Sciences, University of Texas Medical Branch, Galveston (K.E.A.); the Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC (H.L.B.); Royal Gwent Hospital, Newport (A.V.A., C.E.), the Centre for Dermatology, University of Manchester, Salford Royal Hospital, Manchester (L.E.R.), and the Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford (C.R.G.) - all in the United Kingdom; the Department of Medicine, University of California, San Francisco, San Francisco (D.M.B.); the Department of Medicine, University of Alabama, Birmingham (J.B.); the Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany (N.J.N., J.F.); the Department of Internal Medicine, University of Utah, Salt Lake City (C.P., J.D.P.); the Department of Dermatology, Henry Ford Hospital, Detroit (H.W.L., I.H.); Hôpital Louis-Mourier, Hôpitaux Universitaire Paris Nord Val de Seine, Assistance Publique-Hôpitaux de Paris, INSERM Unité 1149, Université Paris Diderot, Colombes, France (J.-C.D.); the Departments of Medicine and Dermatology, University Hospital of Helsinki, Helsinki (R.K.); and the Department of Dermatology, Beaumont Hospital, Dublin (G.M.M.).

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http://dx.doi.org/10.1056/NEJMoa1411481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780255PMC
July 2015

The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3.

J Biol Chem 2014 Dec 4;289(51):35633-43. Epub 2014 Nov 4.

From the Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, Cape Town, South Africa,

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http://dx.doi.org/10.1074/jbc.M114.596411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271245PMC
December 2014

Sensitivity to anti-BRAF therapy: lost in translation.

Pigment Cell Melanoma Res 2015 Jan 30;28(1):4-5. Epub 2014 Sep 30.

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http://dx.doi.org/10.1111/pcmr.12314DOI Listing
January 2015

T-box transcription factors in cancer biology.

Biochim Biophys Acta 2014 Dec 19;1846(2):380-91. Epub 2014 Aug 19.

Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, 7925 Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2014.08.004DOI Listing
December 2014

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma.

Oncotarget 2014 Jul;5(14):5782-97

Ludwig Institute for Cancer Research, Melbourne-Austin Branch, Cancer Immunobiology Laboratory, Heidelberg, VIC 3084, Australia. Department of Medicine, University of Melbourne, Victoria, 3010, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170613PMC
http://dx.doi.org/10.18632/oncotarget.2164DOI Listing
July 2014

Cancer: pathological nuclear reprogramming?

Nat Rev Cancer 2014 Aug 17;14(8):568-73. Epub 2014 Jul 17.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, Old Road Campus Research Building, Old Road Campus, University of Oxford, Headington, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1038/nrc3781DOI Listing
August 2014

Chromatin barcodes as biomarkers for melanoma.

Pigment Cell Melanoma Res 2014 Sep 27;27(5):788-800. Epub 2014 May 27.

Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/pcmr.12258DOI Listing
September 2014

Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression.

Pigment Cell Melanoma Res 2014 Jul 11;27(4):565-79. Epub 2014 Apr 11.

Department of Experimental Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/pcmr.12239DOI Listing
July 2014

Three BRNs are better than two.

Authors:
Colin R Goding

Pigment Cell Melanoma Res 2013 Nov 14;26(6):789-90. Epub 2013 Aug 14.

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http://dx.doi.org/10.1111/pcmr.12150DOI Listing
November 2013

Fishful thinking: the rise and fall of MITF in melanoma.

Authors:
Colin R Goding

Pigment Cell Melanoma Res 2014 Jan 23;27(1):7-8. Epub 2013 Oct 23.

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http://dx.doi.org/10.1111/pcmr.12177DOI Listing
January 2014

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.

Proc Natl Acad Sci U S A 2013 Jul 1;110(29):11893-8. Epub 2013 Jul 1.

Ludwig Institute for Cancer Research Ltd, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1300805110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718163PMC
July 2013

Directed phenotype switching as an effective antimelanoma strategy.

Cancer Cell 2013 Jul 20;24(1):105-19. Epub 2013 Jun 20.

Department of Biochemistry and Molecular Biology A, School of Biology, Regional Campus of International Excellence Campus Mare Nostrum, University of Murcia, 30100 Murcia, Spain.

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http://dx.doi.org/10.1016/j.ccr.2013.05.009DOI Listing
July 2013

The path of least resistance: enhancing the effectiveness of BRAF inhibitors.

Authors:
Colin R Goding

Pigment Cell Melanoma Res 2013 Mar 7. Epub 2013 Mar 7.

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http://dx.doi.org/10.1111/pcmr.12087DOI Listing
March 2013

A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma.

Mol Cell Biol 2012 Nov 17;32(22):4674-83. Epub 2012 Sep 17.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1128/MCB.01067-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486186PMC
November 2012

Biological and mathematical modeling of melanocyte development.

Development 2011 Sep;138(18):3943-54

Institut Curie, Centre de Recherche, Developmental Genetics of Melanocytes, 91405 Orsay, France.

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http://dx.doi.org/10.1242/dev.067447DOI Listing
September 2011

PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration.

Biochem J 2011 Jan;433(1):145-53

Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, Cape Town, South Africa.

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http://dx.doi.org/10.1042/BJ20100886DOI Listing
January 2011

Cancer stem cells versus phenotype-switching in melanoma.

Pigment Cell Melanoma Res 2010 Dec 20;23(6):746-59. Epub 2010 Aug 20.

Department of Dermatology, University Hospital of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1111/j.1755-148X.2010.00757.xDOI Listing
December 2010

Dicing with death: Mitf regulates DICER.

Authors:
Colin R Goding

Pigment Cell Melanoma Res 2010 Aug 16;23(4):483-4. Epub 2010 Jun 16.

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http://dx.doi.org/10.1111/j.1755-148X.2010.00733.xDOI Listing
August 2010

The retinoblastoma protein modulates Tbx2 functional specificity.

Mol Biol Cell 2010 Aug 9;21(15):2770-9. Epub 2010 Jun 9.

Department of Systems Biology, Biomedical Research Institute, University of Warwick, Coventry, CV4 7AL, United Kingdom.

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http://dx.doi.org/10.1091/mbc.E09-12-1029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912361PMC
August 2010

The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining.

Mol Cell 2010 Jan;37(2):282-93

Department of Experimental Oncology, European Institute of Oncology, Milan 20141, Italy.

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http://dx.doi.org/10.1016/j.molcel.2009.12.035DOI Listing
January 2010

Tbx3 represses E-cadherin expression and enhances melanoma invasiveness.

Cancer Res 2008 Oct;68(19):7872-81

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0301DOI Listing
October 2008

Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis.

Gene Expr Patterns 2008 Jul 29;8(6):411-7. Epub 2008 Apr 29.

Wolfson Institute for Biomedical Research and Department of Biology, University College London, Gower Street, London WC1E 6BT, UK.

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http://www.ucl.ac.uk/~ucbzwdr/publications/Pontecorvi%20et%2
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http://linkinghub.elsevier.com/retrieve/pii/S1567133X0800061
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http://dx.doi.org/10.1016/j.gep.2008.04.006DOI Listing
July 2008

TBX3 and its splice variant TBX3 + exon 2a are functionally similar.

Pigment Cell Melanoma Res 2008 Jun 26;21(3):379-87. Epub 2008 Apr 26.

Center for Heart Failure Research, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1755-148X.2008.00461.xDOI Listing
June 2008

UV-mediated regulation of the anti-senescence factor Tbx2.

J Biol Chem 2008 Jan 19;283(4):2223-30. Epub 2007 Nov 19.

Divisions of Medical Biochemistry and Cell Biology, Faculty of Health Sciences, University of Cape Town, Observatory 7925, Cape Town, South Africa.

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http://dx.doi.org/10.1074/jbc.M705651200DOI Listing
January 2008

Melanoma senescence: HDAC1 in focus.

Authors:
Colin R Goding

Pigment Cell Res 2007 Oct;20(5):336-8

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http://dx.doi.org/10.1111/j.1600-0749.2007.00403.xDOI Listing
October 2007

T-box factors: targeting to chromatin and interaction with the histone H3 N-terminal tail.

Pigment Cell Res 2007 Aug;20(4):279-87

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, UK.

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http://dx.doi.org/10.1111/j.1600-0749.2007.00389.xDOI Listing
August 2007

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness.

Genes Dev 2006 Dec;20(24):3426-39

Signalling and Development Laboratory, Marie Curie Research Institute, Oxted, Surrey, RH8 0TL, United Kingdom.

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http://www.genesdev.org/cgi/doi/10.1101/gad.406406
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http://dx.doi.org/10.1101/gad.406406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698449PMC
December 2006

Melanocytes: the new Black.

Authors:
Colin R Goding

Int J Biochem Cell Biol 2007 7;39(2):275-9. Epub 2006 Oct 7.

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 0TL, United Kingdom.

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http://dx.doi.org/10.1016/j.biocel.2006.10.003DOI Listing
June 2007

The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression.

Mol Cell Biol 2006 Dec 25;26(23):8914-27. Epub 2006 Sep 25.

Biochemistry and Molecular Biology, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1128/MCB.02299-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636837PMC
December 2006

Cell cycle regulation of the T-box transcription factor tbx2.

Exp Cell Res 2006 Jul 6;312(12):2358-66. Epub 2006 May 6.

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, RH8 0TL, UK.

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http://dx.doi.org/10.1016/j.yexcr.2006.03.033DOI Listing
July 2006

Regulation of melanoblast and retinal pigment epithelium development by Xenopus laevis Mitf.

Dev Dyn 2005 Nov;234(3):523-34

Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan.

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http://dx.doi.org/10.1002/dvdy.20505DOI Listing
November 2005

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas.

Cancer Res 2005 Mar;65(6):2260-8

Signaling and Development Laboratory, Marie Curie Research Institute, Surrey, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3045DOI Listing
March 2005

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.

Nature 2005 Feb;433(7027):764-9

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 OTL, UK.

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http://dx.doi.org/10.1038/nature03269DOI Listing
February 2005

UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1).

J Biol Chem 2004 Dec 9;279(49):51226-33. Epub 2004 Sep 9.

CNRS UMR 6061 Laboratoire de Génétique et Développement, Faculté de Médecine, Université de Rennes-1, 2 Avenue du Pr. Léon Bernard, 35043 Rennes, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M409768200
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http://dx.doi.org/10.1074/jbc.M409768200DOI Listing
December 2004

The transcription network regulating melanocyte development and melanoma.

Pigment Cell Res 2004 Aug;17(4):318-25

Signalling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey, UK.

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http://dx.doi.org/10.1111/j.1600-0749.2004.00164.xDOI Listing
August 2004

Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromodomain factor Bdf1.

Mol Cell 2004 Jul;15(1):69-81

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1016/j.molcel.2004.05.022DOI Listing
July 2004

The Brn-2 transcription factor links activated BRAF to melanoma proliferation.

Mol Cell Biol 2004 Apr;24(7):2923-31

Signaling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 0TL, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC371133PMC
http://dx.doi.org/10.1128/mcb.24.7.2923-2931.2004DOI Listing
April 2004

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin.

Mol Cell Biol 2004 Apr;24(7):2915-22

Signaling and Development Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 0TL, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC371132PMC
http://dx.doi.org/10.1128/mcb.24.7.2915-2922.2004DOI Listing
April 2004

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor.

Cancer Res 2004 Mar;64(5):1669-74

Signalling and Development Laboratory, Marie Curie Research Institute, Oxted, Surrey, United Kingdom.

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http://cancerres.aacrjournals.org/content/canres/64/5/1669.f
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http://dx.doi.org/10.1158/0008-5472.can-03-3286DOI Listing
March 2004

Cloning and functional analysis of ascidian Mitf in vivo: insights into the origin of vertebrate pigment cells.

Mech Dev 2003 Dec;120(12):1489-504

Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Aramaki-Aza-Aoba, Aoba-ku, Sendai, Miyagi 980-8578, Japan.

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http://dx.doi.org/10.1016/j.mod.2003.08.009DOI Listing
December 2003

Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex.

Mol Cell 2003 Jun;11(6):1609-20

Eukaryotic Transcription Laboratory, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 OTL, United Kingdom.

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http://dx.doi.org/10.1016/s1097-2765(03)00184-9DOI Listing
June 2003

Beta-catenin in the melanocyte lineage.

Pigment Cell Res 2003 Jun;16(3):312-7

Developmental Genetics of Melanocytes, CNRS-Institut Curie, Orsay Cedex, France.

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http://dx.doi.org/10.1034/j.1600-0749.2003.00050.xDOI Listing
June 2003

Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination.

Mol Microbiol 2002 Nov;46(4):947-57

Bikent University, Molecular Biology and Genetics Department, Ankara, Turkey.

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http://dx.doi.org/10.1046/j.1365-2958.2002.03224.xDOI Listing
November 2002

DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).

J Cell Sci 2002 Jan;115(Pt 1):207-16

Bilkent University, Molecular Biology and Genetics Department, 06533, Bilkent, Ankara, Turkey.

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January 2002