Publications by authors named "Colin M House"

19Publications

Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus.

Biochim Biophys Acta Proteins Proteom 2020 09 27;1868(9):140457. Epub 2020 May 27.

Rosie Lew Cancer Immunology Program, Peter MacCallum Cancer Centre, 305 Grattan Street Melbourne 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2020.140457DOI Listing
September 2020

Pits and CtBP Control Tissue Growth in with the Hippo Pathway Transcription Repressor Tgi.

Genetics 2020 05 2;215(1):117-128. Epub 2020 Mar 2.

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia 3000

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http://dx.doi.org/10.1534/genetics.120.303147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198276PMC
May 2020

Regulation of perforin activation and pre-synaptic toxicity through C-terminal glycosylation.

EMBO Rep 2017 10 14;18(10):1775-1785. Epub 2017 Aug 14.

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Vic., Australia

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http://dx.doi.org/10.15252/embr.201744351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623865PMC
October 2017

Real-time visualization of perforin nanopore assembly.

Nat Nanotechnol 2017 05 6;12(5):467-473. Epub 2017 Feb 6.

London Centre for Nanotechnology, University College London, London WC1H 0AH, UK.

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http://dx.doi.org/10.1038/nnano.2016.303DOI Listing
May 2017

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood 2015 Nov 7;126(21):2392-403. Epub 2015 Oct 7.

Cancer Therapeutics Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia;

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http://dx.doi.org/10.1182/blood-2015-03-632984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653767PMC
November 2015

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.

Oncotarget 2015 Jan;6(2):862-73

Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston 4006, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359261PMC
http://dx.doi.org/10.18632/oncotarget.2696DOI Listing
January 2015

Foxp3 expression in macrophages associated with RENCA tumors in mice.

PLoS One 2014 29;9(9):e108670. Epub 2014 Sep 29.

Cancer Immunology Research Program, Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia; Department of Immunology, Monash University, Prahran, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108670PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180934PMC
November 2015

Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.

Cancer Res 2012 Apr 21;72(7):1694-704. Epub 2012 Feb 21.

Cancer Genomics and Genetics, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3310DOI Listing
April 2012

Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.

Enzyme Res 2011 22;2011:720985. Epub 2011 Aug 22.

Growth Control and Differentiation Program, Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Melbourne, VIC 8006, Australia.

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http://dx.doi.org/10.4061/2011/720985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160084PMC
November 2011

A phospho-proteomic screen identifies novel S6K1 and mTORC1 substrates revealing additional complexity in the signaling network regulating cell growth.

Cell Signal 2011 Aug 1;23(8):1338-47. Epub 2011 Apr 1.

Research Division, Peter MacCallum Cancer Centre, Melbourne, Locked Bag 1, A'Beckett Street, Victoria 8006, Australia.

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http://dx.doi.org/10.1016/j.cellsig.2011.03.016DOI Listing
August 2011

Siah proteins: novel drug targets in the Ras and hypoxia pathways.

Cancer Res 2009 Dec 17;69(23):8835-8. Epub 2009 Nov 17.

Cancer Genomics and Genetics Laboratory, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1676DOI Listing
December 2009

Elucidation of the substrate binding site of Siah ubiquitin ligase.

Structure 2006 Apr;14(4):695-701

Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, Locked Bag 1 A'Beckett Street, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1016/j.str.2005.12.013DOI Listing
April 2006

A binding motif for Siah ubiquitin ligase.

Proc Natl Acad Sci U S A 2003 Mar 7;100(6):3101-6. Epub 2003 Mar 7.

Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne 8006, Victoria, Australia.

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http://dx.doi.org/10.1073/pnas.0534783100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152253PMC
March 2003

Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.

Nat Struct Biol 2002 Jan;9(1):68-75

Biota Structural Biology Laboratory, St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia.

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http://www.nature.com/doifinder/10.1038/nsb743
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http://dx.doi.org/10.1038/nsb743DOI Listing
January 2002