Publications by authors named "Colin J D Ross"

57Publications

Challenges and Opportunities in Implementing Pharmacogenetic Testing in Clinical Settings.

Annu Rev Pharmacol Toxicol 2021 01 2;61:65-84. Epub 2020 Oct 2.

Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V6H 3V4, Canada; email:

View Article and Find Full Text PDF
January 2021

Prevention of adverse drug effects: a pharmacogenomic approach.

Curr Opin Pediatr 2020 Oct;32(5):646-653

Department of Medical Genetics, Faculty of Medicine, University of British Columbia.

View Article and Find Full Text PDF
October 2020

CRISPR/Cas9 Editing: Sparking Discussion on Safety in Light of the Need for New Therapeutics.

Hum Gene Ther 2020 Aug 24;31(15-16):794-807. Epub 2020 Jul 24.

Faculty of Pharmaceutical Sciences; University of British Columbia, Vancouver, Canada.

View Article and Find Full Text PDF
August 2020

Genome-Wide Association Studies of Drug-Induced Liver Injury Make Progress Beyond the HLA Region.

Gastroenterology 2019 10 23;157(4):1167-1168. Epub 2019 Jul 23.

Division of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
October 2019

Pharmacogenomics of Cisplatin-Induced Ototoxicity: Successes, Shortcomings, and Future Avenues of Research.

Clin Pharmacol Ther 2019 08 12;106(2):350-359. Epub 2019 Jun 12.

BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
August 2019

Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months.

EBioMedicine 2019 Feb 30;40:655-662. Epub 2019 Jan 30.

BC Children's Hospital Research Institute, Vancouver, Canada; Pediatrics, University of British Columbia, Vancouver, Canada. Electronic address:

View Article and Find Full Text PDF
February 2019

Analyses of Adverse Drug Reactions-Nationwide Active Surveillance Network: Canadian Pharmacogenomics Network for Drug Safety Database.

J Clin Pharmacol 2019 03 19;59(3):356-363. Epub 2018 Nov 19.

Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
March 2019

HUME: large-scale detection of causal genetic factors of adverse drug reactions.

Bioinformatics 2018 12;34(24):4274-4283

Department of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada.

View Article and Find Full Text PDF
December 2018

Exploring genetic influences underlying acute aerobic exercise effects on motor learning.

Sci Rep 2017 09 21;7(1):12123. Epub 2017 Sep 21.

Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, Canada.

View Article and Find Full Text PDF
September 2017

Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy.

PM R 2018 03 1;10(3):235-243. Epub 2017 Sep 1.

Division of Rehabilitation Medicine, Children's Mercy-Kansas City, 2401 Gillham Road, Kansas City, MO 64108; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO.

View Article and Find Full Text PDF
March 2018

Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell lines.

PLoS One 2017 13;12(4):e0175711. Epub 2017 Apr 13.

Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
April 2017

Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.

Br J Clin Pharmacol 2017 05 19;83(5):1143-1145. Epub 2017 Mar 19.

BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
May 2017

Identification of a large intronic transposal insertion in SLC17A5 causing sialic acid storage disease.

Orphanet J Rare Dis 2017 02 10;12(1):28. Epub 2017 Feb 10.

Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

View Article and Find Full Text PDF
February 2017

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

Pharmacogenet Genomics 2016 Jan;26(1):28-39

aTranslational Laboratory in Genetic Medicine, Agency for Science, Technology, and Research bSaw Swee Hock School of Public Health cNUS Graduate School for Integrative Sciences and Engineering dLife Sciences Institute Departments of eStatistics and Applied Probability fMedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore Departments of gParasitology hAnatomy, University of Colombo, Colombo, Sri Lanka iDepartment of Pediatrics, Division of Translational Therapeutics jCentre for Molecular Medicine and Therapeutics, Child and Family Research Institute kDepartment of Medicine, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
January 2016

Use of pharmacogenomics in pediatric renal transplant recipients.

Front Genet 2015 18;6:41. Epub 2015 Feb 18.

Pharmaceutical Outcomes Programme, Pediatrics, BC Children's Hospital, University of British Columbia Vancouver, BC, Canada ; Division of Translational Therapeutics, Department of Paediatrics, Faculty of Medicine, University of British Columbia Vancouver, BC, Canada ; Child and Family Research Institute, University of British Columbia Vancouver, BC, Canada.

View Article and Find Full Text PDF
March 2015

A single bout of high-intensity aerobic exercise facilitates response to paired associative stimulation and promotes sequence-specific implicit motor learning.

J Appl Physiol (1985) 2014 Dec 25;117(11):1325-36. Epub 2014 Sep 25.

Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, Canada; Graduate Program in Neuroscience, Faculty of Medicine, University of British Columbia, Vancouver, Canada

View Article and Find Full Text PDF
December 2014

Codeine-related deaths: The role of pharmacogenetics and drug interactions.

Forensic Sci Int 2014 Jun 26;239:50-6. Epub 2014 Mar 26.

Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Canada; Toxicology Section, Centre of Forensic Sciences, Toronto, Canada. Electronic address:

View Article and Find Full Text PDF
June 2014

Promoting neuroplasticity for motor rehabilitation after stroke: considering the effects of aerobic exercise and genetic variation on brain-derived neurotrophic factor.

Phys Ther 2013 Dec 1;93(12):1707-16. Epub 2013 Aug 1.

C.S. Mang, BPE, MSc, Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
December 2013

From mutation identification to therapy: discovery and origins of the first approved gene therapy in the Western world.

Hum Gene Ther 2013 May;24(5):472-8

Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands.

View Article and Find Full Text PDF
May 2013

Cancer pharmacogenomics in children: research initiatives and progress to date.

Paediatr Drugs 2013 Apr;15(2):71-81

Department of Pediatrics, Division of Pediatric Hematology/Oncology/BMT, University of British Columbia, Vancouver, BC, Canada.

View Article and Find Full Text PDF
April 2013

Postpartum maternal codeine therapy and the risk of adverse neonatal outcomes: the devil is in the details.

Ther Drug Monit 2012 Aug;34(4):378-80

Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
August 2012

Suspected opioid overdose case resolved by CYP2D6 genotyping.

Ther Drug Monit 2012 Apr;34(2):121-3

Division of Translational Therapeutics, Department of Paediatrics, Faculty of Medicine, University of British Columbia, Canada.

View Article and Find Full Text PDF
April 2012

Amelioration of hypertriglyceridemia with hypo-alpha-cholesterolemia in LPL deficient mice by hematopoietic cell-derived LPL.

PLoS One 2011 29;6(9):e25620. Epub 2011 Sep 29.

Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University, Beijing, China.

View Article and Find Full Text PDF
January 2012

Pharmacogenomics of serious adverse drug reactions in pediatric oncology.

J Popul Ther Clin Pharmacol 2011 21;18:e134-51. Epub 2011 Mar 21.

Department of Medical Genetics, University of British Columbia (UBC), Centre for Molecular Medicine and Therapeutics,

View Article and Find Full Text PDF
August 2011

Fatal hydrocodone overdose in a child: pharmacogenetics and drug interactions.

Pediatrics 2010 Oct 13;126(4):e986-9. Epub 2010 Sep 13.

Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, 555 University Ave, Toronto, ON, Canada M5G 1X8.

View Article and Find Full Text PDF
October 2010

The Canadian Pharmacogenomics Network for Drug Safety: a model for safety pharmacology.

Thyroid 2010 Jul;20(7):681-7

Department of Medical Genetics, Faculty of Medicine, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada.

View Article and Find Full Text PDF
July 2010

Genotypic approaches to therapy in children: a national active surveillance network (GATC) to study the pharmacogenomics of severe adverse drug reactions in children.

Ann N Y Acad Sci 2007 Sep;1110:177-92

Department of Medical Genetics, University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.

View Article and Find Full Text PDF
September 2007

Pharmacogenomics and its implications for autoimmune disease.

J Autoimmun 2007 Mar-May;28(2-3):122-8. Epub 2007 Apr 5.

Department of Medical Genetics, University of British Columbia (UBC), Centre for Molecular Medicine and Therapeutics, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.

View Article and Find Full Text PDF
July 2007

Hemorheological abnormalities in lipoprotein lipase deficient mice with severe hypertriglyceridemia.

Biochem Biophys Res Commun 2006 Mar 25;341(4):1066-71. Epub 2006 Jan 25.

Institute of Cardiovascular Sciences, Health Science Center, Peking University, Beijing 100083, China.

View Article and Find Full Text PDF
March 2006

Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation.

Arterioscler Thromb Vasc Biol 2005 Oct 7;25(10):2143-50. Epub 2005 Jul 7.

Department of Medical Genetics, University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada.

View Article and Find Full Text PDF
October 2005