Colin A Hodgkinson

Colin A Hodgkinson

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Colin A Hodgkinson

Colin A Hodgkinson

Publications by authors named "Colin A Hodgkinson"

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TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.

Addict Biol 2019 Nov 12:e12838. Epub 2019 Nov 12.

National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/adb.12838DOI Listing
November 2019

Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.

Neuropsychopharmacology 2019 Aug 29. Epub 2019 Aug 29.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41386-019-0500-yDOI Listing
August 2019

Early-Life Adversity and Blunted Stress Reactivity as Predictors of Alcohol and Drug use in Persons With COMT (rs4680) Val158Met Genotypes.

Alcohol Clin Exp Res 2019 Jul 31;43(7):1519-1527. Epub 2019 May 31.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1111/acer.14079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602827PMC
July 2019

Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype.

Proc Natl Acad Sci U S A 2019 Jun 10;116(26):13107-13115. Epub 2019 Jun 10.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20852;

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http://dx.doi.org/10.1073/pnas.1820410116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600920PMC
June 2019

Joint Impact of Early Life Adversity and COMT Val158Met (rs4680) Genotypes on the Adult Cortisol Response to Psychological Stress.

Psychosom Med 2017 Jul/Aug;79(6):631-637

From the VA Medical Center (Lovallo, Sorocco); Department of Psychiatry and Behavioral Sciences (Lovallo, Cohoon), University of Oklahoma Health Sciences Center, Oklahoma City; Laboratory of Neurogenetics (Enoch, Hodgkinson, Goldman), National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland; Donald W. Reynolds Department of Geriatric Medicine (Sorocco), University of Oklahoma Health Sciences Center, Oklahoma City; Cognitive Science Research Center (Vincent), University of Oklahoma, Norman; Department of Psychiatry (Acheson), University of Texas Health Sciences Center at San Antonio; and Research Imaging Institute (Acheson), San Antonio, Texas.

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http://dx.doi.org/10.1097/PSY.0000000000000481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489380PMC
April 2018

Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors.

Transl Psychiatry 2018 03 27;8(1):72. Epub 2018 Mar 27.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, 20852, USA.

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http://dx.doi.org/10.1038/s41398-018-0120-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913313PMC
March 2018

Severity of alcohol dependence is associated with the fatty acid amide hydrolase Pro129Thr missense variant.

Addict Biol 2018 01 1;23(1):474-484. Epub 2017 Feb 1.

Section on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/adb.12491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538894PMC
January 2018

The Leu72Met Polymorphism of the Prepro-ghrelin Gene is Associated With Alcohol Consumption and Subjective Responses to Alcohol: Preliminary Findings.

Alcohol Alcohol 2017 Jul;52(4):425-430

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism (NIAAA) and National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), 10 Center Drive (10CRC/15330), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/alcalc/agx021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860519PMC
July 2017

Hepatic, lipid and genetic factors associated with obesity: crosstalk with alcohol dependence?

World J Biol Psychiatry 2017 03 1;18(2):120-128. Epub 2016 Dec 1.

a Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology , National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse , Bethesda , MD , USA.

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http://dx.doi.org/10.1080/15622975.2016.1249952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382351PMC
March 2017

Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel.

Int J Neuropsychopharmacol 2016 Sep 21;19(9). Epub 2016 Sep 21.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland (Drs Gitik, Srivastava, and Hodgkinson, Ms Shen, and Dr Goldman); Department of Radiology and Biomedical Imaging, University of California, San Francisco, California (Dr Meyerhoff); Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, California (Dr Meyerhoff).Current address (V.S.): Molecular Genetic Technology Program, School of Health Professions, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043642PMC
http://dx.doi.org/10.1093/ijnp/pyw033DOI Listing
September 2016

The abundance of cis-acting loci leading to differential allele expression in F1 mice and their relationship to loci harboring genes affecting complex traits.

BMC Genomics 2016 08 11;17(1):620. Epub 2016 Aug 11.

Laboratory of Neurogenetics, National institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20852, USA.

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http://dx.doi.org/10.1186/s12864-016-2922-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982227PMC
August 2016

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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https://genepi.qimr.edu.au/contents/p/staff/Schwantes_An_Beh
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http://link.springer.com/10.1007/s10519-015-9737-3
Publisher Site
http://dx.doi.org/10.1007/s10519-015-9737-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence.

Hum Brain Mapp 2015 Dec 14;36(12):4808-18. Epub 2015 Sep 14.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/hbm.22951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715530PMC
December 2015

Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation.

Alcohol Clin Exp Res 2015 Sep 24;39(9):1665-70. Epub 2015 Jul 24.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology , National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland.

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http://doi.wiley.com/10.1111/acer.12814
Publisher Site
http://dx.doi.org/10.1111/acer.12814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921193PMC
September 2015

FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice.

Neuropsychopharmacology 2014 Jul 7;39(8):2029-38. Epub 2014 Mar 7.

Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/npp.2014.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059914PMC
July 2014

Differential impact of serotonin transporter activity on temperament and behavior in persons with a family history of alcoholism in the Oklahoma Family Health Patterns Project.

Alcohol Clin Exp Res 2014 Jun 5;38(6):1575-81. Epub 2014 May 5.

Department of Psychiatry and Behavioral Sciences , University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Behavioral Sciences Laboratories , Veterans Affairs Medical Center, Oklahoma City, Oklahoma.

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http://doi.wiley.com/10.1111/acer.12412
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http://dx.doi.org/10.1111/acer.12412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047646PMC
June 2014

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption.

Proc Natl Acad Sci U S A 2013 Oct 30;110(42):16963-8. Epub 2013 Sep 30.

Laboratories of Neurogenetics and Clinical and Translational Studies and Section on Synaptic Pharmacology, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.

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http://dx.doi.org/10.1073/pnas.1309839110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800985PMC
October 2013

The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement.

PLoS One 2013 24;8(1):e54108. Epub 2013 Jan 24.

Laureate Institute for Brain Research, and Department of Psychiatry, University of Oklahoma College of Medicine, Tulsa, Oklahoma, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054108PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554713PMC
July 2013

A large-scale candidate gene analysis of mood disorders: evidence of neurotrophic tyrosine kinase receptor and opioid receptor signaling dysfunction.

Psychiatr Genet 2013 Apr;23(2):47-55

Department of Psychiatry, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1097/YPG.0b013e32835d7028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869619PMC
April 2013

BDNF polymorphism-dependent OFC and DLPFC plasticity differentially moderates implicit and explicit bias.

Cereb Cortex 2012 Nov 28;22(11):2602-9. Epub 2011 Nov 28.

Imaging Sciences Training Program, Radiology and Imaging Sciences, Clinical Center and National Institute of Biomedical Imaging and Bioengineering, National, Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/cercor/bhr337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464413PMC
November 2012

Oxytocin gene polymorphisms influence human dopaminergic function in a sex-dependent manner.

Biol Psychiatry 2012 Aug 13;72(3):198-206. Epub 2012 Mar 13.

Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan 48109-0720, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392442PMC
August 2012

Striatal dopamine release and genetic variation of the serotonin 2C receptor in humans.

J Neurosci 2012 Jul;32(27):9344-50

Department of Psychiatry and Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan 48109-5720, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1260-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431013PMC
July 2012

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.

Alcohol Clin Exp Res 2011 Feb 17;35(2):304-16. Epub 2010 Nov 17.

From the Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1111/j.1530-0277.2010.01346.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026908PMC
February 2011

A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction.

Proc Natl Acad Sci U S A 2010 Jul 19;107(30):13509-14. Epub 2010 Jul 19.

Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, USA.

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http://dx.doi.org/10.1073/pnas.1004745107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922167PMC
July 2010

More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.

Neuropsychopharmacology 2010 Feb 4;35(3):613-22. Epub 2009 Nov 4.

Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/npp2009166
Publisher Site
http://dx.doi.org/10.1038/npp.2009.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945903PMC
February 2010

The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.

Biol Psychiatry 2010 Jan;67(1):20-7

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland 20892-9412, USA.

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http://dx.doi.org/10.1016/j.biopsych.2009.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964936PMC
January 2010

Association of substance use disorders with childhood trauma but not African genetic heritage in an African American cohort.

Am J Psychiatry 2009 Sep 15;166(9):1031-40. Epub 2009 Jul 15.

Division of Psychological Medicine, PO63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK.

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http://dx.doi.org/10.1176/appi.ajp.2009.08071068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768270PMC
September 2009

GABRG1 and GABRA2 as independent predictors for alcoholism in two populations.

Neuropsychopharmacology 2009 Apr 24;34(5):1245-54. Epub 2008 Sep 24.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/npp.2008.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656604PMC
April 2009

Common genetic origins for EEG, alcoholism and anxiety: the role of CRH-BP.

PLoS One 2008 31;3(10):e3620. Epub 2008 Oct 31.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003620PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575401PMC
February 2009

Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo.

J Neurosci 2008 Oct;28(44):11354-9

Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan 48109-0720, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2391-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613649PMC
October 2008

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding.

Hum Mol Genet 2008 Aug 10;17(16):2462-73. Epub 2008 May 10.

Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, USA.

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http://dx.doi.org/10.1093/hmg/ddn146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486442PMC
August 2008

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.

Alcohol Clin Exp Res 2008 May 4;32(5):785-95. Epub 2008 Mar 4.

Institute of Clinical Medicine, College of Medicine, National Cheng Kung University Hospital 138, National Cheng Kung University, Sheng-Li Road, Tainan 704, Taiwan.

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http://dx.doi.org/10.1111/j.1530-0277.2008.00642.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665790PMC
May 2008

Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

Mol Pain 2007 Jul 26;3:20. Epub 2007 Jul 26.

Clinical Pain Research Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, DHHS, Bethesda, MD, USA.

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http://dx.doi.org/10.1186/1744-8069-3-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072938PMC
July 2007

Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia.

Biol Psychiatry 2007 May 19;61(10):1208-10. Epub 2006 Oct 19.

Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, New York 11004, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.07.023DOI Listing
May 2007

The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populations.

Neuropsychopharmacology 2007 Jan 16;32(1):190-6. Epub 2006 Aug 16.

Section of Human Neurogenetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/sj.npp.1301177DOI Listing
January 2007

DISC1 and neurocognitive function in schizophrenia.

Neuroreport 2005 Aug;16(12):1399-402

Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, New York, USA.

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http://dx.doi.org/10.1097/01.wnr.0000175248.25535.f6DOI Listing
August 2005

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

Am J Hum Genet 2004 Nov 22;75(5):862-72. Epub 2004 Sep 22.

Section of Human Neurogenetics and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.

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http://dx.doi.org/10.1086/425586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182115PMC
November 2004