Colette T Dooley

Colette T Dooley

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Colette T Dooley

Colette T Dooley

Publications by authors named "Colette T Dooley"

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Antinociceptive activity of thiazole-containing cyclized DAMGO and Leu-(Met) enkephalin analogs.

Org Biomol Chem 2019 06 16;17(21):5305-5315. Epub 2019 May 16.

Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA.

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http://dx.doi.org/10.1039/c9ob00882aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637423PMC
June 2019

A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluation.

Org Biomol Chem 2017 Sep;15(37):7796-7801

Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, P. R. China.

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http://dx.doi.org/10.1039/c7ob01924fDOI Listing
September 2017

Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors.

J Med Chem 2015 Jun 4;58(12):4905-17. Epub 2015 Jun 4.

Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, Florida 34987, United States.

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http://dx.doi.org/10.1021/jm501637cDOI Listing
June 2015

Synthesis and analgesic activity of alkylated, reduced and constrained oligoheterocyclic peptidomimetic analogs of Leu-enkephalin.

Bioorg Med Chem Lett 2014 Sep 8;24(18):4482-4485. Epub 2014 Aug 8.

Torrey Pines Institute for Molecular Studies, Port Saint Lucie, FL 34987, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.07.090DOI Listing
September 2014

Ligand/kappa-opioid receptor interactions: insights from the X-ray crystal structure.

Eur J Med Chem 2013 Aug 30;66:114-21. Epub 2013 May 30.

Instituto de Química, UNAM, Av. Universidad 3000, México DF, Mexico.

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http://dx.doi.org/10.1016/j.ejmech.2013.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775475PMC
August 2013

Fluorescent mu selective opioid ligands from a mixture based cyclic peptide library.

ACS Comb Sci 2012 Dec 8;14(12):673-9. Epub 2012 Nov 8.

Torrey Pines Institute for Molecular Studies, Port Saint Lucie, Florida 34987, United States.

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http://pubs.acs.org/doi/10.1021/co300110t
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http://dx.doi.org/10.1021/co300110tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607207PMC
December 2012

A novel method for the determination of isokinetic ratios and its application in the synthesis of two new positional scanning libraries.

ACS Comb Sci 2012 Sep 28;14(9):503-12. Epub 2012 Aug 28.

Torrey Pines Institute for Molecular Studies , 11350 SW Village Parkway, Port St. Lucie, Florida 34987, United States.

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http://dx.doi.org/10.1021/co300060sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825827PMC
September 2012

Toxicity of 6-hydroxydopamine: live cell imaging of cytoplasmic redox flux.

Cell Biol Toxicol 2012 Apr 8;28(2):89-101. Epub 2012 Jan 8.

Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA.

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http://dx.doi.org/10.1007/s10565-011-9209-3DOI Listing
April 2012

Integrating computational and mixture-based screening of combinatorial libraries.

J Mol Model 2011 Jun 21;17(6):1473-82. Epub 2010 Sep 21.

Torrey Pines Institute for Molecular Studies, Port St Lucie, FL 34987, USA.

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http://dx.doi.org/10.1007/s00894-010-0850-1DOI Listing
June 2011

Use and implications of the harmonic mean model on mixtures for basic research and drug discovery.

ACS Comb Sci 2011 May 11;13(3):337-44. Epub 2011 Mar 11.

Torrey Pines Institute for Molecular Studies , Port St. Lucie, Florida 34987, United States.

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http://dx.doi.org/10.1021/co100065aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096014PMC
May 2011

Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.

Bioorg Med Chem 2009 Aug 21;17(15):5583-97. Epub 2009 Jun 21.

Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Room 132, Port St. Lucie, FL 34987, USA.

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http://dx.doi.org/10.1016/j.bmc.2009.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746904PMC
August 2009

Conformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis.

Bioorg Med Chem 2008 Jun 27;16(11):5932-8. Epub 2008 Apr 27.

Torrey Pines Institute for Molecular Studies, 5775 Old Dixie Highway, Fort Pierce, FL 34946, USA.

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http://dx.doi.org/10.1016/j.bmc.2008.04.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533277PMC
June 2008

Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries.

Bioorg Med Chem Lett 2006 Aug 5;16(16):4331-8. Epub 2006 Jun 5.

Torrey Pines Institute for Molecular Studies, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2006.05.053DOI Listing
August 2006

In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands.

AAPS J 2006 May 26;8(2):E371-82. Epub 2006 May 26.

Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1007/BF02854908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231577PMC
May 2006

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.

J Biol Chem 2004 May 25;279(21):22284-93. Epub 2004 Feb 25.

Department of Chemistry and Biochemistry, University of California-San Diego, La Jolla, California 92093-0647, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M312847200
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http://dx.doi.org/10.1074/jbc.M312847200DOI Listing
May 2004

De novo identification of highly active fluorescent kappa opioid ligands from a rhodamine labeled tetrapeptide positional scanning library.

Bioorg Med Chem Lett 2004 Apr;14(8):1947-51

Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2004.01.090DOI Listing
April 2004