Clive R Pullinger

Clive R Pullinger

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Clive R Pullinger

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Partial deletions: rare copy-number variants contributing towards severe hypertriglyceridemia.

J Lipid Res 2019 Nov 13;60(11):1953-1958. Epub 2019 Sep 13.

Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5B7, Canada

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http://dx.doi.org/10.1194/jlr.P119000335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824486PMC
November 2019

Levels of prebeta-1 high-density lipoprotein are elevated in 3 phenotypes of dyslipidemia.

J Clin Lipidol 2018 Jan - Feb;12(1):99-109. Epub 2017 Nov 14.

Cardiovascular Research Institute, University of California, San Francisco, CA, USA; Department of Physiological Nursing, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.11.001DOI Listing
July 2019

Severe hypertriglyceridemia is primarily polygenic.

J Clin Lipidol 2019 Jan - Feb;13(1):80-88. Epub 2018 Oct 24.

Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2018.10.006DOI Listing
October 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Moderate statin treatment reduces prebeta-1 high-density lipoprotein levels in dyslipidemic patients.

J Clin Lipidol 2017 Jul - Aug;11(4):908-914. Epub 2017 May 4.

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Physiological Nursing, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.04.118DOI Listing
February 2018

Cytokine polymorphisms are associated with daytime napping in adults living with HIV.

Sleep Med 2017 Apr 20;32:162-170. Epub 2017 Jan 20.

Department of Family Health Care Nursing, University of California at San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.sleep.2016.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628054PMC
April 2017

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.

N Engl J Med 2017 04 5;376(17):1647-1658. Epub 2017 Apr 5.

From the Departments of Medicine (A.P.B., M.A.M., N.P.S., X.H., C.M.A., M.L., L.G.F., S.G.Y.), Rheumatology (M.A.M.), Human Genetics (K.R., S.G.Y.), and Pathology and Laboratory Medicine (P.T.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, and the Cardiovascular Research Institute and Department of Physiological Nursing, University of California, San Francisco, San Francisco (C.R.P.); the Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi (K.M., T.M., M.M., K.N.), and the Department of Insured Medical Care Management, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo (M.A.) - both in Japan; the Finsen Laboratory, Rigshospitalet, Copenhagen (M.P.); the Department of Medicine, University of Cape Town, Cape Town, South Africa (D.J.B.); the Departments of Medicine and Pharmacology, Vanderbilt University Medical Center, Nashville (M.F.L.); the Department of Medicine, Faculty of Medicine, Chulalongkorn University and Thai Red Cross Society, Bangkok, Thailand (W.K.); Clinique de Prévention Cardiovasculaire, Institut de Recherches Cliniques de Montréal, University of Montreal, Montreal (R.D.); the Department of Medicine, University of Texas Southwestern Medical Center, Dallas (A.G.); the Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, New York University School of Medicine, New York (I.J.G.); and Fédération d'Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, INSERM UMR-1060 Carmen, Université de Lyon, Lyon, France (P.M., S.C.).

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http://dx.doi.org/10.1056/NEJMoa1611930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555413PMC
April 2017

Familial hypercholesterolaemia: cholesterol efflux and coronary disease.

Eur J Clin Invest 2016 Jul 20;46(7):643-50. Epub 2016 Jun 20.

Department of Internal Medicine, Section of Pharmacology, Vascular and Metabolic Diseases, Cardiovascular Research School COEUR, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/eci.12643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113689PMC
July 2016

Identification and metabolic profiling of patients with lysosomal acid lipase deficiency.

J Clin Lipidol 2015 Sep-Oct;9(5):716-26.e1. Epub 2015 Jul 26.

Cardiovascular Research Institute, University of California, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, CA, USA; Department of Biochemistry and Biophysics.

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http://dx.doi.org/10.1016/j.jacl.2015.07.008DOI Listing
June 2016

Cytokine polymorphisms and plasma levels are associated with sleep onset insomnia in adults living with HIV/AIDS.

Brain Behav Immun 2015 Jul 20;47:58-65. Epub 2014 Dec 20.

Department of Family Health Care Nursing, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2014.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468032PMC
July 2015

Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291).

Arterioscler Thromb Vasc Biol 2014 Oct 14;34(10):2254-60. Epub 2014 Aug 14.

From the Children's Hospital Oakland Research Institute, CA (V.S., A.W., J.B.S., L.N., J.A.B., G.W., T.M.F., R.O.R.); Department of Obstetrics, Gynecology and Reproductive Sciences, UCSF Sandler-Moore Mass Spectrometry Core Facility, San Francisco, CA (H.E.W., A.D.); and Cardiovascular Research Institute, University of California, San Francisco (C.R.P., J.P.K., M.J.M.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178935PMC
October 2014

Cytokine polymorphisms are associated with fatigue in adults living with HIV/AIDS.

Brain Behav Immun 2014 Aug 12;40:95-103. Epub 2014 Mar 12.

Department of Physiological Nursing, University of California, San Francisco, CA, USA; Institute for Human Genetics, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.bbi.2014.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102618PMC
August 2014

Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties.

Thromb Res 2014 May 26;133(5):863-7. Epub 2014 Jan 26.

Institute of Cardiology, Jagiellonian University School of Medicine, Cracow, Poland.

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http://dx.doi.org/10.1016/j.thromres.2014.01.024DOI Listing
May 2014

Polymorphisms of interleukin-1 Beta and interleukin-17Alpha genes are associated with restless legs syndrome.

Biol Res Nurs 2014 Apr 3;16(2):143-51. Epub 2013 Mar 3.

1Department of Women, Children, and Family Health Sciences, University of Illinois, Chicago, IL, USA.

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http://journals.sagepub.com/doi/ 10.1177/1099800413478827
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http://dx.doi.org/10.1177/1099800413478827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697711PMC
April 2014

Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease.

Heart Rhythm 2014 Apr 17;11(4):646-52. Epub 2014 Jan 17.

Section of Cardiac Electrophysiology, Department of Medicine. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2014.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989347PMC
April 2014

Impact of a 4q25 genetic variant in atrial flutter and on the risk of atrial fibrillation after cavotricuspid isthmus ablation.

J Cardiovasc Electrophysiol 2014 Mar 13;25(3):271-277. Epub 2013 Dec 13.

Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.

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http://doi.wiley.com/10.1111/jce.12317
Publisher Site
http://dx.doi.org/10.1111/jce.12317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947706PMC
March 2014

Cytokine polymorphisms are associated with poor sleep maintenance in adults living with human immunodeficiency virus/acquired immunodeficiency syndrome.

Sleep 2014 Mar 1;37(3):453-63. Epub 2014 Mar 1.

Department of Physiological Nursing, University of California at San Francisco, San Francisco, CA ; Institute for Human Genetics, University of California at San Francisco, San Francisco, CA.

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http://dx.doi.org/10.5665/sleep.3474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920310PMC
March 2014

Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population.

Metab Syndr Relat Disord 2014 Feb 22;12(1):25-30. Epub 2013 Oct 22.

1 Cardiovascular Research Institute and Department of Physiological Nursing, University of California , San Francisco, California.

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http://dx.doi.org/10.1089/met.2013.0086DOI Listing
February 2014

Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus.

Sleep 2014 Jan 1;37(1):157-66. Epub 2014 Jan 1.

Department of Physiological Nursing, University of California at San Francisco, San Francisco, CA ; Institute for Human Genetics, University of California at San Francisco, San Francisco, CA.

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http://dx.doi.org/10.5665/sleep.3328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902878PMC
January 2014

Epigenetic regulation and measurement of epigenetic changes.

Biol Res Nurs 2013 Oct 3;15(4):373-81. Epub 2012 Jun 3.

1Department of Physiological Nursing, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1099800412444785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839622PMC
October 2013

Types of sleep problems in adults living with HIV/AIDS.

J Clin Sleep Med 2012 Feb 15;8(1):67-75. Epub 2012 Feb 15.

Department of Family Health Care Nursing, University of California, San Francisco, CA 94143-0606, USA.

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http://dx.doi.org/10.5664/jcsm.1666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266344PMC
February 2012

Risk factors and symptoms associated with pain in HIV-infected adults.

J Assoc Nurses AIDS Care 2010 Mar-Apr;21(2):125-33. Epub 2010 Jan 29.

Department of Physiological Nursing and Institute for Human Genetics, University of California, San Francisco, USA.

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http://dx.doi.org/10.1016/j.jana.2009.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832225PMC
June 2010

The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles.

Atherosclerosis 2010 Apr 12;209(2):498-503. Epub 2009 Oct 12.

Department of Medicine, University of California San Diego, La Jolla, CA 92093-0682, United States.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.09.077DOI Listing
April 2010

Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.

Metab Syndr Relat Disord 2009 Dec;7(6):543-8

Diabetes Center and Department of Medicine, University of California, San Francisco, California 94115, USA.

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http://dx.doi.org/10.1089/met.2009.0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139525PMC
December 2009

Symptom experience in HIV-infected adults: a function of demographic and clinical characteristics.

J Pain Symptom Manage 2009 Dec;38(6):882-93

Department of Family Health Care Nursing, University of California, San Francisco, California 94143-0606, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2009.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794949PMC
December 2009

Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.

J Lipid Res 2009 Jul 23;50(7):1330-9. Epub 2009 Feb 23.

Pfizer Global Research and Development, Department of Cardiovascular and Metabolic Diseases, Groton, CT 06340, USA.

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http://dx.doi.org/10.1194/jlr.M900034-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694332PMC
July 2009

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia.

Nat Genet 2007 Dec 11;39(12):1483-7. Epub 2007 Nov 11.

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ng.2007.24DOI Listing
December 2007

Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery.

Anesthesiology 2007 Sep;107(3):406-11

Anesthesia and Perioperative Care, University of California, San Francisco, California 94143-0648, USA.

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http://dx.doi.org/10.1097/01.anes.0000278905.07899.dfDOI Listing
September 2007

Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia.

J Lipid Res 2006 Apr 30;47(4):787-93. Epub 2005 Dec 30.

Department of Physiological Nursing, School of Nursing, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1194/jlr.M500476-JLR200DOI Listing
April 2006

Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors.

Hum Mutat 2005 Jan;25(1):18-21

Cardiovascular Research Institute, University of California, San Francisco 94143-0130, USA.

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http://doi.wiley.com/10.1002/humu.20121
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http://dx.doi.org/10.1002/humu.20121DOI Listing
January 2005

Regulation of ATP-binding cassette transporter A1 transcription by thyroid hormone receptor.

Biochemistry 2004 Feb;43(6):1626-32

Cardiovascular Research Institute, San Francisco, California 94143-0130, USA.

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http://dx.doi.org/10.1021/bi0301643DOI Listing
February 2004

Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids.

J Lipid Res 2003 Jun 1;44(6):1167-73. Epub 2003 Apr 1.

Department of Physiological Nursing, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1194/jlr.M200480-JLR200DOI Listing
June 2003

Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts.

Biochem Biophys Res Commun 2003 Jun;306(2):463-8

Cardiovascular Research Institute, University of California, San Francisco, CA 94143-0130, USA.

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http://dx.doi.org/10.1016/s0006-291x(03)00992-6DOI Listing
June 2003

Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders.

Expert Rev Cardiovasc Ther 2003 May;1(1):107-19

Cardiovascular Research Institute, University of California, San Francisco, USA.

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http://dx.doi.org/10.1586/14779072.1.1.107DOI Listing
May 2003

Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding.

Clin Chim Acta 2002 Jul;321(1-2):113-21

Department of Pathological Biochemistry, Glasgow Royal Infirmary, North Glasgow Hospital University NHS Trust, Fourth floor, Queen Elizabeth Building, Alexandra Parade, Glasgow G31 2ER, Scotland, UK.

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http://dx.doi.org/10.1016/s0009-8981(02)00106-7DOI Listing
July 2002