Publications by authors named "Clifton L Dalgard"

52Publications

Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred.

Neurology 2020 Oct 19. Epub 2020 Oct 19.

Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000011064DOI Listing
October 2020

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Authors:
Qian Zhang Paul Bastard Zhiyong Liu Jérémie Le Pen Marcela Moncada-Velez Jie Chen Masato Ogishi Ira K D Sabli Stephanie Hodeib Cecilia Korol Jérémie Rosain Kaya Bilguvar Junqiang Ye Alexandre Bolze Benedetta Bigio Rui Yang Andrés Augusto Arias Qinhua Zhou Yu Zhang Fanny Onodi Sarantis Korniotis Léa Karpf Quentin Philippot Marwa Chbihi Lucie Bonnet-Madin Karim Dorgham Nikaïa Smith William M Schneider Brandon S Razooky Hans-Heinrich Hoffmann Eleftherios Michailidis Leen Moens Ji Eun Han Lazaro Lorenzo Lucy Bizien Philip Meade Anna-Lena Neehus Aileen Camille Ugurbil Aurélien Corneau Gaspard Kerner Peng Zhang Franck Rapaport Yoann Seeleuthner Jeremy Manry Cecile Masson Yohann Schmitt Agatha Schlüter Tom Le Voyer Taushif Khan Juan Li Jacques Fellay Lucie Roussel Mohammad Shahrooei Mohammed F Alosaimi Davood Mansouri Haya Al-Saud Fahd Al-Mulla Feras Almourfi Saleh Zaid Al-Muhsen Fahad Alsohime Saeed Al Turki Rana Hasanato Diederik van de Beek Andrea Biondi Laura Rachele Bettini Mariella D'Angio Paolo Bonfanti Luisa Imberti Alessandra Sottini Simone Paghera Eugenia Quiros-Roldan Camillo Rossi Andrew J Oler Miranda F Tompkins Camille Alba Isabelle Vandernoot Jean-Christophe Goffard Guillaume Smits Isabelle Migeotte Filomeen Haerynck Pere Soler-Palacin Andrea Martin-Nalda Roger Colobran Pierre-Emmanuel Morange Sevgi Keles Fatma Çölkesen Tayfun Ozcelik Kadriye Kart Yasar Sevtap Senoglu Şemsi Nur Karabela Carlos Rodríguez Gallego Giuseppe Novelli Sami Hraiech Yacine Tandjaoui-Lambiotte Xavier Duval Cédric Laouénan Andrew L Snow Clifton L Dalgard Joshua Milner Donald C Vinh Trine H Mogensen Nico Marr András N Spaan Bertrand Boisson Stéphanie Boisson-Dupuis Jacinta Bustamante Anne Puel Michael Ciancanelli Isabelle Meyts Tom Maniatis Vassili Soumelis Ali Amara Michel Nussenzweig Adolfo García-Sastre Florian Krammer Aurora Pujol Darragh Duffy Richard Lifton Shen-Ying Zhang Guy Gorochov Vivien Béziat Emmanuelle Jouanguy Vanessa Sancho-Shimizu Charles M Rice Laurent Abel Luigi D Notarangelo Aurélie Cobat Helen C Su Jean-Laurent Casanova

Science 2020 Sep 24. Epub 2020 Sep 24.

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France. University of Paris, Imagine Institute, Paris, France. Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA. Department of Paediatric Infectious Diseases & Virology, Imperial College London, Norfolk Place, London, UK. Yale Center for Genome Analysis and Department of Genetics, Yale School of Medicine, New Haven, CT, USA. Zukerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA. Helix, San Mateo, CA, USA. Primary Immunodeficiencies Group, University of Antioquia UdeA, Medellin, Colombia. School of Microbiology, University of Antioquia UdeA, Medellin, Colombia. Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA. NIAID Clinical Genomics Program, National Institutes of Health, Bethesda, MD, USA. Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France. Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR 7212, Université de Paris, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Paris, France. Sorbonne Université, Inserm, Centre d'immunologie et des maladies infectieuses-Paris (CIMI PARIS), AP-HP Hôpital Pitié-Salpêtrière, Paris, France. Translational Immunology Lab, Institut Pasteur, Paris, France. Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, Department of Pediatrics, University Hospitals Leuven, KU Leuven, Belgium. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Sorbonne Université, UMS037, PASS, Plateforme de cytométrie de la Pitié-Salpêtrière CyPS, F-75013 Paris, France. Bioinformatics Platform, Structure Fédérative de Recherche Necker, INSERM UMR1163, Université de Paris, Imagine Institute, Paris, France. Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran i Reynals, CIBERER U759, and Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain. Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar. School of Life sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. Swiss Institue of Bioinformatics, Lausanne, Switzerland. Infectious Disease Susceptibility Program, Research Institute-McGill University Health Centre, Montréal, Québec, Canada. Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran. Department of Microbiology and Immunology, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium. Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia. Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of, Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti, University of Medical Sciences, Tehran, Iran. Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti, Iran. National Center of Genomics Technology, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia. Dasman Diabetes Institute, Department of Genetics and Bioinformatics, Kuwait. Immunology Research Laboratory, Department of Pediatrics, College of Medicine and King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia. Translational Pathology, Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Misery of National Guard- Health Affairs, Riyadh, Saudi Arabia. Cancer & Blood Research, King Abdullah International Medical Research Center, Riyadh, KSA. Amsterdam UMC, Department of Neurology, Amsterdam Neuroscience, Amsterdam, Netherlands. Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo, Monza, Italy. Department of Infectious Diseases, San Gerardo Hospital - University of Milano-Bicocca, Monza, Italy. CREA Laboratory, Diagnostic Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy. Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali di Brescia, Brescia, Italy. Chief Medical Officer, ASST Spedali Civili di Brescia, Brescia, Italy. Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, MD, USA. PRIMER, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Center of Human Genetics, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. Department of Internal Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. Fonds de la Recherche Scientifique (FNRS) and Center of Human Genetics, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. Department of Paediatric Immunology and Pulmonology, Centre for Primary Immunodeficiency Ghent (CPIG), PID research lab, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Ghent, Belgium. Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus. Universitat Autònoma de Barcelona (UAB). Barcelona, Catalonia, Spain. Immunology Division, Genetics Department. Hospital Universitari Vall d'Hebron. Vall d'Hebron Research Institute. Vall d'Hebron Barcelona Hospital Campus. Universitat Autònoma de Barcelona (UAB). Barcelona, Catalonia, Spain. Aix Marseille Univ, INSERM, INRAE, C2VN, CHU Timone, Marseille, France. Necmettin Erbakan University, Meram Medical Faculty, Division of Pediatric Allergy and Immunology, Konya, Turkey. Department of Infectious Diseases and Clinical Microbiology, Konya Training and Research Hospital, Konya, Turkey. Bilkent University, Department of Molecular Biology and Genetics, Bilkent - Ankara 06800, Turkey. Departments of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. Department of Immunology, Hospital Universitario de G.C. Dr. Negrín, Canarian Health System, Las Palmas de Gran Canaria, Spain. University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain. Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy. Intensive Care Unit, AP-HM, Marseille, France. Avicenne Hospital Intensive Care Unit, APHP, Bobigny, INSERM U1272 Hypoxia & Lung, Paris, France. PH Réanimation CHU Avicenne, Bobigny, INSERM U1272 Hypoxie & Poumon, Paris, France. Université de Paris, IAME UMR-S 1137, INSERM, Paris, France, EU. Inserm CIC 1425, Paris, France. AP-HP, Département Epidémiologie Biostatistiques et Recherche Clinique, Hôpital Bichat, Paris, France, EU. Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Division of Pediatric Allergy, Immunology and Rheumatology, Columbia University, New York, USA. Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark. Department of Biomedicine, Aarhus University, Denmark. College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands. Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, 75015 Paris, France. Turnstone Biologics, New York, NY, USA. Department of Pediatrics, University Hospitals Leuven, KU Leuven, Belgium. New York Genome Center, New York, NY, USA. Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, Laboratoire d'Immunologie, Paris, France. Laboratory of Molecular Immunology, Rockefeller University, New York, NY, USA. Howard Hughes Medical Institute, New York, NY, USA. Department of Medicine, Division of Infectiosu Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Laboratory of Genetics and Genomics, The Rockefeller University, New York, NY, USA. Department of Genetics, Yale University School of Medicine, New Haven, CT, USA. Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT, USA. Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.abd4570DOI Listing
September 2020

MutEnricher: a flexible toolset for somatic mutation enrichment analysis of tumor whole genomes.

BMC Bioinformatics 2020 Jul 31;21(1):338. Epub 2020 Jul 31.

The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-020-03695-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393734PMC
July 2020

The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight.

Authors:
Sara Bandres-Ciga Sarah Ahmed Marya S Sabir Cornelis Blauwendraat Astrid D Adarmes-Gómez Inmaculada Bernal-Bernal Marta Bonilla-Toribio Dolores Buiza-Rueda Fátima Carrillo Mario Carrión-Claro Pilar Gómez-Garre Silvia Jesús Miguel A Labrador-Espinosa Daniel Macias Carlota Méndez-Del-Barrio Teresa Periñán-Tocino Cristina Tejera-Parrado Laura Vargas-González Monica Diez-Fairen Ignacio Alvarez Juan Pablo Tartari Mariateresa Buongiorno Miquel Aguilar Ana Gorostidi Jesús Alberto Bergareche Elisabet Mondragon Ana Vinagre-Aragon Ioana Croitoru Javier Ruiz-Martínez Oriol Dols-Icardo Jaime Kulisevsky Juan Marín-Lahoz Javier Pagonabarraga Berta Pascual-Sedano Mario Ezquerra Ana Cámara Yaroslau Compta Manel Fernández Rubén Fernández-Santiago Esteban Muñoz Eduard Tolosa Francesc Valldeoriola Isabel Gonzalez-Aramburu Antonio Sanchez Rodriguez María Sierra Manuel Menéndez-González Marta Blazquez Ciara Garcia Esther Suarez-San Martin Pedro García-Ruiz Juan Carlos Martínez-Castrillo Lydia Vela-Desojo Clara Ruz Francisco Javier Barrero Francisco Escamilla-Sevilla Adolfo Mínguez-Castellanos Debora Cerdan Cesar Tabernero Maria Jose Gomez Heredia Francisco Perez Errazquin Manolo Romero-Acebal Cici Feliz Jose Luis Lopez-Sendon Marina Mata Irene Martínez Torres Jonggeol Jeffrey Kim Clifton L Dalgard Janet Brooks Sara Saez-Atienzar J Raphael Gibbs Rafael Jorda Juan A Botia Luis Bonet-Ponce Karen E Morrison Carl Clarke Manuela Tan Huw Morris Connor Edsall Dena Hernandez Javier Simon-Sanchez Mike A Nalls Sonja W Scholz Adriano Jimenez-Escrig Jacinto Duarte Francisco Vives Raquel Duran Janet Hoenicka Victoria Alvarez Jon Infante Maria José Marti Jordi Clarimón Adolfo López de Munain Pau Pastor Pablo Mir Andrew Singleton

Mov Disord 2019 12 29;34(12):1851-1863. Epub 2019 Oct 29.

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mds.27864DOI Listing
December 2019

FOXP3 protects conventional human T cells from premature restimulation-induced cell death.

Cell Mol Immunol 2019 Oct 28. Epub 2019 Oct 28.

Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20817, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41423-019-0316-zDOI Listing
October 2019

Sleep Deprivation Alters the Pituitary Stress Transcriptome in Male and Female Mice.

Front Endocrinol (Lausanne) 2019 9;10:676. Epub 2019 Oct 9.

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fendo.2019.00676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794367PMC
October 2019

Digitoxin Inhibits Epithelial-to-Mesenchymal-Transition in Hereditary Castration Resistant Prostate Cancer.

Front Oncol 2019 2;9:630. Epub 2019 Aug 2.

Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine-America's Medical School, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2019.00630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687970PMC
August 2019

Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells.

J Neuroinflammation 2019 Aug 9;16(1):164. Epub 2019 Aug 9.

Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12974-019-1553-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688278PMC
August 2019

Correction to: Region- and time-dependent gene regulation in the amygdala and anterior cingulate cortex of a PTSD-like mouse model.

Mol Brain 2019 May 9;12(1):47. Epub 2019 May 9.

Department of Anatomy, Physiology and Genetics, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13041-019-0470-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509754PMC
May 2019

Region- and time-dependent gene regulation in the amygdala and anterior cingulate cortex of a PTSD-like mouse model.

Mol Brain 2019 03 28;12(1):25. Epub 2019 Mar 28.

Department of Anatomy, Physiology and Genetics, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13041-019-0449-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438009PMC
March 2019

Linked read technology for assembling large complex and polyploid genomes.

BMC Genomics 2018 Sep 4;19(1):651. Epub 2018 Sep 4.

Department of Agronomy, Iowa State University, Ames, IA, 50011, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-018-5040-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122573PMC
September 2018

Identification of a Small Molecule That Selectively Inhibits ERG-Positive Cancer Cell Growth.

Cancer Res 2018 07 30;78(13):3659-3671. Epub 2018 Apr 30.

Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-2949DOI Listing
July 2018

Neonatal mouse cortical but not isogenic human astrocyte feeder layers enhance the functional maturation of induced pluripotent stem cell-derived neurons in culture.

Glia 2018 04 12;66(4):725-748. Epub 2017 Dec 12.

Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/glia.23278DOI Listing
April 2018

The role of the immunoproteasome in interferon-γ-mediated microglial activation.

Sci Rep 2017 08 24;7(1):9365. Epub 2017 Aug 24.

Neuroscience Program, Uniformed Services University of the Health Sciences, F. Edward Hébert School of Medicine, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-09715-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571106PMC
August 2017

Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells.

Front Immunol 2017 2;8:913. Epub 2017 Aug 2.

Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2017.00913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539167PMC
August 2017

Salsalate treatment following traumatic brain injury reduces inflammation and promotes a neuroprotective and neurogenic transcriptional response with concomitant functional recovery.

Brain Behav Immun 2017 Mar 7;61:96-109. Epub 2016 Dec 7.

Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA; Center for Neuroscience and Regenerative Medicine, Uniformed Services University, Bethesda, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbi.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316369PMC
March 2017

Bone morphogenetic protein-2-mediated pain and inflammation in a rat model of posterolateral arthrodesis.

BMC Neurosci 2016 12 1;17(1):80. Epub 2016 Dec 1.

Department of Pharmacology and Molecular Therapeutics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12868-016-0314-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134101PMC
December 2016

"Soldier's Heart": A Genetic Basis for Elevated Cardiovascular Disease Risk Associated with Post-traumatic Stress Disorder.

Front Mol Neurosci 2016 23;9:87. Epub 2016 Sep 23.

Department of Psychiatry Uniformed Services University School of Medicine, Uniformed Services University of the Health SciencesBethesda, MD, USA; Center for the Study of Traumatic stress, Uniformed Services University of the Health SciencesBethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnmol.2016.00087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033971PMC
September 2016

MicroRNA Expression Profiling of the Armed Forces Health Surveillance Branch Cohort for Identification of "Enviro-miRs" Associated With Deployment-Based Environmental Exposure.

J Occup Environ Med 2016 08;58(8 Suppl 1):S97-S103

Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland (Dr Dalgard, Mr Polston, Mr Sukumar, Drs Wilkerson, Pollard); Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland (Drs Dalgard, Wilkerson, Pollard); The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland (Drs Dalgard, Wilkerson, Pollard); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon). The opinions expressed are those of the authors and do not necessarily reflect the official positions of the Uniformed Services University, the U.S. Departments of Defense, the Army and the Air Force, the 779th Aerospace Medical Squadron, the U.S. Army Public Health Center (Provisional), Emory University, Clarkson University, or the University of Rochester.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JOM.0000000000000764DOI Listing
August 2016

Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.

J Occup Environ Med 2016 08;58(8 Suppl 1):S3-S11

Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); 779th Aerospace Medical Squadron, 79th Medical WingJoint Base Andrews, Maryland (Dr Rohrbeck); Bioenvironmental Engineering Flight Commander, 30th Medical Group, 338 South Dakota Ave, Vandenberg AFB, CA 93437 (Maj Haines); Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Atlanta, Georgia (Dr Jones, Mr Walker); Departments of Medicine and Environmental Medicine, University of Rochester Medical Center (Drs Utell, Phipps, Thatcher, Woeller); Center for Air Resources Engineering and Science, Institute for a Sustainable Environment, Clarkson University, Potsdam, New York (Dr Hopke); U.S Army Center for Public Health (Provisional), Aberdeen Proving Ground (Drs Baird, Gaydos); and Anatomy and Cell Biology, Uniformed Services University, Bethesda, Maryland (Drs Pollard, Dalgard).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JOM.0000000000000775DOI Listing
August 2016

Inhibition of the histone demethylase Kdm5b promotes neurogenesis and derepresses Reln (reelin) in neural stem cells from the adult subventricular zone of mice.

Mol Biol Cell 2016 Feb 6;27(4):627-39. Epub 2016 Jan 6.

Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E15-07-0513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750923PMC
February 2016

Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis.

Front Pharmacol 2015 13;6:168. Epub 2015 Aug 13.

Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2015.00168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534802PMC
August 2015

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells.

Oncotarget 2015 Jul;6(21):18504-17

Department of Surgery, VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621906PMC
http://dx.doi.org/10.18632/oncotarget.4181DOI Listing
July 2015

A novel analytical brain block tool to enable functional annotation of discriminatory transcript biomarkers among discrete regions of the fronto-limbic circuit in primate brain.

Brain Res 2015 Mar 18;1600:42-58. Epub 2014 Dec 18.

Department of Anatomy, Physiology and Genetics, and Center for Medical Proteomics, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences (USUHS), 4301 Jones Bridge Road, Bethesda, MD 20914, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2014.12.031DOI Listing
March 2015

p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.

J Biol Chem 2014 Dec 20;289(50):34921-37. Epub 2014 Oct 20.

From the Department of Surgery, Veterans Affairs Greater Los Angeles Healthcare System/David Geffen School of Medicine at UCLA, Los Angeles, California 90073, Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California 90095

View Article

Download full-text PDF

Source
http://www.jbc.org/content/289/50/34921.full.pdf
Web Search
http://www.jbc.org/lookup/doi/10.1074/jbc.M114.568543
Publisher Site
http://dx.doi.org/10.1074/jbc.M114.568543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263890PMC
December 2014

Genotoxic changes to rodent cells exposed in vitro to tungsten, nickel, cobalt and iron.

Int J Environ Res Public Health 2014 Mar 10;11(3):2922-40. Epub 2014 Mar 10.

Daniel K. Inouye Graduate School of Nursing, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph110302922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987013PMC
March 2014

Oncogenic herpesvirus HHV-8 promotes androgen-independent prostate cancer growth.

Cancer Res 2013 Sep 4;73(18):5695-708. Epub 2013 Sep 4.

Authors' Affiliation: Emerging Infectious Diseases Program, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/content/73/18/5695.full.pd
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-12-4196DOI Listing
September 2013

Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression.

J Carcinog 2013 20;12. Epub 2013 May 20.

Department of Anatomy, Physiology, and Genetics, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1477-3163.112268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709410PMC
July 2013

808 nm wavelength light induces a dose-dependent alteration in microglial polarization and resultant microglial induced neurite growth.

Lasers Surg Med 2013 Apr;45(4):253-63

Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Jones Bridge Road, Bethesda, Maryland 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lsm.22133DOI Listing
April 2013

Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics.

Front Neurol 2012 31;3:155. Epub 2012 Oct 31.

Department of Microbiology and Immunology, Uniformed Services University Bethesda, MD, USA ; Center for Neuroscience and Regenerative Medicine, Uniformed Services University Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2012.00155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484408PMC
November 2012

The cytokine temporal profile in rat cortex after controlled cortical impact.

Front Mol Neurosci 2012 25;5. Epub 2012 Jan 25.

Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnmol.2012.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265961PMC
October 2012

Histone deacetylase inhibitors SAHA and sodium butyrate block G1-to-S cell cycle progression in neurosphere formation by adult subventricular cells.

BMC Neurosci 2011 May 26;12:50. Epub 2011 May 26.

Department of Anatomy, Physiology and Genetics, Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

View Article

Download full-text PDF

Source
http://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2
Publisher Site
http://dx.doi.org/10.1186/1471-2202-12-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123242PMC
May 2011

Differential microRNA-34a expression and tumor suppressor function in retinoblastoma cells.

Invest Ophthalmol Vis Sci 2009 Oct 14;50(10):4542-51. Epub 2009 May 14.

Ocular Oncology Unit, Department of Ophthalmology, University of California at San Francisco, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/data/Journals/IOVS/933243/z7g01
Web Search
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
Publisher Site
http://dx.doi.org/10.1167/iovs.09-3520DOI Listing
October 2009

Survival and invasiveness of astrocytomas promoted by erythropoietin.

J Neurosurg 2007 Feb;106(2):338-50

Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/jns.2007.106.2.338DOI Listing
February 2007

Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

J Biol Chem 2005 Dec 13;280(51):41928-39. Epub 2005 Oct 13.

Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M508718200DOI Listing
December 2005