Clifford A Lowell

Clifford A Lowell

UNVERIFIED PROFILE

Are you Clifford A Lowell?   Register this Author

Register author
Clifford A Lowell

Clifford A Lowell

Publications by authors named "Clifford A Lowell"

Are you Clifford A Lowell?   Register this Author

100Publications

1905Reads

14Profile Views

Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.

Cancer Immunol Res 2020 Apr 28;8(4):428-435. Epub 2020 Jan 28.

Olivia Newton-John Cancer Research Institute and La Trobe University School of Cancer Medicine, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-19-0623DOI Listing
April 2020

Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils.

J Clin Invest 2020 Jan;130(1):389-403

Department of Laboratory Medicine, UCSF, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI130952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934192PMC
January 2020

CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases.

Sci Signal 2019 Oct 8;12(602). Epub 2019 Oct 8.

Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aao3829DOI Listing
October 2019

CRAC channel regulation of innate immune cells in health and disease.

Cell Calcium 2019 03 9;78:56-65. Epub 2019 Jan 9.

Department of Laboratory Medicine, University of California, San Francisco, CA, United States.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01434160183018
Publisher Site
http://dx.doi.org/10.1016/j.ceca.2019.01.003DOI Listing
March 2019

Neutrophils: Their Role in Innate and Adaptive Immunity 2017.

J Immunol Res 2017;2017:9748345. Epub 2017 Nov 7.

Facultad de Odontología, Universidad Nacional Autónoma de México, 04510 Ciudad de México, Mexico.

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/jir/2017/9748345/
Publisher Site
http://dx.doi.org/10.1155/2017/9748345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697120PMC
January 2019

Shp1 function in myeloid cells.

J Leukoc Biol 2017 09 12;102(3):657-675. Epub 2017 Jun 12.

Department of Laboratory Medicine and Immunology Program, University of California, San Francisco, California, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.2MR0317-105RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557645PMC
September 2017

STIM1 and STIM2 cooperatively regulate mouse neutrophil store-operated calcium entry and cytokine production.

Blood 2017 09 19;130(13):1565-1577. Epub 2017 Jul 19.

Department of Laboratory Medicine, University of California, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2016-11-751230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620414PMC
September 2017

B cell autoimmunity at the extremes.

Nat Immunol 2017 09;18(10):1065-1066

Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.3840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334840PMC
September 2017

Efficiency and Specificity of Gene Deletion in Lung Epithelial Doxycycline-Inducible Cre Mice.

Am J Respir Cell Mol Biol 2017 08;57(2):248-257

Department of Laboratory Medicine and Program in Immunology, University of California, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2016-0208OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576580PMC
August 2017

Neutrophils: Their Role in Innate and Adaptive Immunity.

J Immunol Res 2016 24;2016:1469780. Epub 2016 Feb 24.

Facultad de Odontología, Universidad Nacional Autónoma de México, 04510 Ciudad de México, DF, Mexico.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/1469780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783580PMC
November 2016

Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting.

Bio Protoc 2016 Nov;6(22)

Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21769/BioProtoc.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293249PMC
November 2016

MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase.

PLoS Pathog 2016 08 19;12(8):e1005787. Epub 2016 Aug 19.

Departments of Pediatrics, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1005787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991787PMC
August 2016

Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells.

Am J Respir Cell Mol Biol 2016 06;54(6):802-13

Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2015-0171OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942217PMC
June 2016

Neutrophils in animal models of autoimmune disease.

Semin Immunol 2016 04 7;28(2):174-86. Epub 2016 Apr 7.

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA 94143, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867286PMC
April 2016

The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation.

Immunity 2016 Jan 5;44(1):73-87. Epub 2016 Jan 5.

Department of Anesthesiology, Intensive Care and Pain Medicine, University of Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149 Münster, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2015.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030078PMC
January 2016

Store-operated calcium signaling in neutrophils.

J Leukoc Biol 2015 Oct 24;98(4):497-502. Epub 2015 Feb 24.

Departments of *Pediatrics and Laboratory Medicine and the Program in Immunology, University of California, San Francisco, California, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.2MR1114-573RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763866PMC
October 2015

Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses.

Immunity 2015 Oct 6;43(4):764-75. Epub 2015 Oct 6.

Department of Microbiology and Immunology, University of California, San Francisco and Howard Hughes Medical Institute, CA 94143, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2015.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618158PMC
October 2015

LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.

Elife 2015 Oct 30;4. Epub 2015 Oct 30.

Russell/Engleman Rheumatology Research Center, Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, United States.

View Article

Download full-text PDF

Source
http://elifesciences.org/content/elife/4/e09183.full.pdf
Web Search
http://elifesciences.org/lookup/doi/10.7554/eLife.09183
Publisher Site
http://dx.doi.org/10.7554/eLife.09183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626889PMC
October 2015

The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.

J Immunol 2015 Sep 31;195(5):2383-95. Epub 2015 Jul 31.

Section of General Pathology, Department of Pathology and Diagnostics, University of Verona, Verona, 37134, Italy; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1402011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546890PMC
September 2015

Intracellular signalling during neutrophil recruitment.

Cardiovasc Res 2015 Aug 21;107(3):373-85. Epub 2015 May 21.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://cardiovascres.oxfordjournals.org/content/cardiovascre
Web Search
http://cardiovascres.oxfordjournals.org/lookup/doi/10.1093/c
Publisher Site
http://dx.doi.org/10.1093/cvr/cvv159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502828PMC
August 2015

Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.

J Immunol 2015 Aug 22;195(3):1152-61. Epub 2015 Jun 22.

Department of Anesthesiology, Intensive Care, and Pain Medicine, University of Münster, 48149 Münster, Germany; Max-Planck Institute for Molecular Biomedicine, 48149 Münster, Germany; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1500606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506862PMC
August 2015

The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

J Exp Med 2014 Sep 15;211(10):1993-2011. Epub 2014 Sep 15.

Department of Physiology, Semmelweis University School of Medicine, 1094 Budapest, Hungary MTA-SE "Lendület" Inflammation Physiology Research Group of the Hungarian Academy of Sciences and the Semmelweis University, and MTA-SE "Lendület" Lymphatic Physiology Research Group of the Hungarian Academy of Sciences and the Semmelweis University, 1094 Budapest, Hungary

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20132496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172222PMC
September 2014

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*.

Crit Care Med 2014 Jul;42(7):1676-87

1Department of Medicine, University of California San Francisco, San Francisco, CA. 2Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA. 3Blood Systems Research Institute, San Francisco, CA. 4Department of Medicine, Mayo Clinic, Rochester, MN. 5Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA. 6Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA. 7Department of Anesthesia, Mayo Clinic, Rochester, MN. 8Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN. 9American Red Cross Neutrophil Reference Laboratory, St. Paul, MN. 10Blood Centers of the Pacific, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000000323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284060PMC
July 2014

Expression of the TEL-Syk fusion protein in hematopoietic stem cells leads to rapidly fatal myelofibrosis in mice.

PLoS One 2013 8;8(10):e77542. Epub 2013 Oct 8.

Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077542PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792906PMC
June 2014

ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use.

Cell Metab 2014 Jun 22;19(6):1020-33. Epub 2014 May 22.

Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2014.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274740PMC
June 2014

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice.

J Immunol Methods 2014 Jun 22;408:89-100. Epub 2014 May 22.

Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, CA 94143, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jim.2014.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105345PMC
June 2014

Actin cytoskeleton reorganization by Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering.

Dev Cell 2014 Jun;29(5):534-546

Program in Cell Biology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, Toronto, ON M5C 1N8, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2014.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083245PMC
June 2014

The multifaceted functions of neutrophils.

Annu Rev Pathol 2014 16;9:181-218. Epub 2013 Sep 16.

Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 20115; email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-pathol-020712-164023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277181PMC
March 2014

Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma.

Clin Cancer Res 2014 Feb 4;20(4):1029-41. Epub 2013 Nov 4.

Authors' Affiliations: Division of Hematology/Oncology, Genentech, South San Francisco; Helen Diller Comprehensive Cancer Center; and Department of Radiology, Laboratory Medicine, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-0474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944388PMC
February 2014

B cell-specific loss of Lyn kinase leads to autoimmunity.

J Immunol 2014 Feb 27;192(3):919-28. Epub 2013 Dec 27.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1301979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900234PMC
February 2014

Molecular editing of cellular responses by the high-affinity receptor for IgE.

Science 2014 Feb 6;343(6174):1021-5. Epub 2014 Feb 6.

Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.1246976
Publisher Site
http://dx.doi.org/10.1126/science.1246976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188507PMC
February 2014

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice.

Immunity 2013 Mar;38(3):489-501

Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613338PMC
March 2013

Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization.

Dev Cell 2013 Feb 7;24(4):372-83. Epub 2013 Feb 7.

Program in Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2013.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586299PMC
February 2013

Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.

J Cell Sci 2012 Nov 12;125(Pt 22):5535-45. Epub 2012 Sep 12.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://jcs.biologists.org/lookup/doi/10.1242/jcs.111260
Publisher Site
http://dx.doi.org/10.1242/jcs.111260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561861PMC
November 2012

Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens.

J Biol Chem 2012 Oct 17;287(41):34149-56. Epub 2012 Aug 17.

Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M112.382812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464523PMC
October 2012

Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans.

Anesth Analg 2012 Mar 19;114(3):511-9. Epub 2012 Jan 19.

Department of Anesthesia & Perioperative Care, University of California, San Francisco, Box 0648, San Francisco, CA 94143-0648, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0b013e318241fcd5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927839PMC
March 2012

Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa.

J Leukoc Biol 2012 Feb 10;91(2):275-84. Epub 2011 Nov 10.

Department of Medicine, University of California at San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1189/jlb.0711356
Publisher Site
http://dx.doi.org/10.1189/jlb.0711356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290427PMC
February 2012

Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury.

J Exp Med 2012 Feb 30;209(2):407-21. Epub 2012 Jan 30.

Department of Anesthesiology and Critical Care Medicine, University of Münster, 48149 Münster, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20111493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280874PMC
February 2012

Overview: studying integrins in vivo.

Methods Mol Biol 2012 ;757:369-97

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-61779-166-6_22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248401PMC
January 2012

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.

Proc Natl Acad Sci U S A 2012 Jan 20;109(1):267-72. Epub 2011 Dec 20.

Immunology Program, Benaroya Research Institute, Seattle, WA 98101, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1111957108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252908PMC
January 2012

Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus.

Immunity 2011 Nov 10;35(5):757-69. Epub 2011 Nov 10.

Department of Medicine, Howard Hughes Medical Institute, Rosalind Russell Medical Research Center for Arthritis, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2011.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245876PMC
November 2011

The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells.

J Immunol 2011 Oct 31;187(7):3806-14. Epub 2011 Aug 31.

Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Unité Mixte de Recherche 5089, 31077 Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1101245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276309PMC
October 2011

B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice.

Proc Natl Acad Sci U S A 2011 Oct 12;108(41):E823-32. Epub 2011 Sep 12.

Department of Laboratory Medicine and Microbiology/Immunology, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1107913108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193193PMC
October 2011

Deletion of Syk in neutrophils prevents immune complex arthritis.

J Immunol 2011 Oct 14;187(8):4319-30. Epub 2011 Sep 14.

Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1100341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186826PMC
October 2011

Interferon-γ production by neutrophils during bacterial pneumonia in mice.

Am J Respir Crit Care Med 2011 May 17;183(10):1391-401. Epub 2010 Dec 17.

Center for Airways Disease, Department of Medicine, University of North Carolina, Chapel Hill, NC 27599-7248, USA.

View Article

Download full-text PDF

Source
http://www.atsjournals.org/doi/abs/10.1164/rccm.201004-0592O
Publisher Site
http://dx.doi.org/10.1164/rccm.201004-0592OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114063PMC
May 2011

Neutrophils give us a shock.

J Clin Invest 2011 Apr 23;121(4):1260-3. Epub 2011 Mar 23.

Department of Laboratory Medicine, UCSF, San Francisco, California 94143-0451, USA.

View Article

Download full-text PDF

Source
http://www.jci.org/articles/view/57296
Publisher Site
http://dx.doi.org/10.1172/JCI57296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069799PMC
April 2011

Differential transformation capacity of Src family kinases during the initiation of prostate cancer.

Proc Natl Acad Sci U S A 2011 Apr 4;108(16):6579-84. Epub 2011 Apr 4.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1103904108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080985PMC
April 2011

Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.

Cold Spring Harb Perspect Biol 2011 Mar 1;3(3). Epub 2011 Mar 1.

Department of Laboratory Medicine, University of California, San Francisco, 94143, USA.

View Article

Download full-text PDF

Source
http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
Publisher Site
http://dx.doi.org/10.1101/cshperspect.a002352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039931PMC
March 2011

Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection.

J Immunol 2011 Feb 27;186(3):1656-65. Epub 2010 Dec 27.

Program in Immunology, Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1002093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248398PMC
February 2011

IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.

J Immunol 2011 Feb 10;186(4):2372-81. Epub 2011 Jan 10.

Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1002558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274743PMC
February 2011

Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.

J Exp Med 2010 Aug 12;207(8):1757-73. Epub 2010 Jul 12.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20100086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916124PMC
August 2010

An important role of the SRC family kinase Lyn in stimulating platelet granule secretion.

J Biol Chem 2010 Apr 26;285(17):12559-70. Epub 2010 Feb 26.

Department of Pharmacology, College of Medicine, University of Illinois, Chicago, Illinois 60612, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.098756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857081PMC
April 2010

Leukocyte adhesion deficiency syndrome: a controversy solved.

Immunol Cell Biol 2009 Aug-Sep;87(6):440-2. Epub 2009 May 5.

Department of Laboratory Medicine, University of California-San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/icb.2009.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464832PMC
March 2010

Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection.

Blood 2009 Nov 1;114(23):4871-82. Epub 2009 Oct 1.

Immunology Program and the Department of Laboratory Medicine, University of California-San Francisco, 513 Parnassus Ave., San Francisco, CA 94143-0451, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2009-05-220806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786293PMC
November 2009

Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury.

J Clin Invest 2009 Nov 5;119(11):3450-61. Epub 2009 Oct 5.

Department of Medicine, UCSF, San Francisco, California 94143-0130, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI38432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769181PMC
November 2009

The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.

Immunol Rev 2009 Nov;232(1):42-58

Immunology Program, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-065X.2009.00841.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248395PMC
November 2009

The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina.

Infect Immun 2009 May 2;77(5):1790-7. Epub 2009 Mar 2.

Department of Medicine, University of Alabama-Birmingham, 1900 University Blvd., THT 437A, Birmingham, AL 35294, USA.

View Article

Download full-text PDF

Source
http://iai.asm.org/cgi/doi/10.1128/IAI.01441-08
Publisher Site
http://dx.doi.org/10.1128/IAI.01441-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681740PMC
May 2009

The ins and outs of leukocyte integrin signaling.

Annu Rev Immunol 2009 ;27:339-62

Program in Immunology, Department of Laboratory Medicine, University of California, San Francisco, California 94143-0451, USA.

View Article

Download full-text PDF

Source
http://www.annualreviews.org/doi/10.1146/annurev.immunol.021
Publisher Site
http://dx.doi.org/10.1146/annurev.immunol.021908.132554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248397PMC
May 2009

Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.

Clin Cancer Res 2009 Mar 10;15(6):1989-97. Epub 2009 Mar 10.

Division of Hematology/Oncology, Department of Neurological Surgery, University of California at San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-08-2054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372389PMC
March 2009

Multiple roles of Lyn kinase in myeloid cell signaling and function.

Immunol Rev 2009 Mar;228(1):23-40

Department of Laboratory Medicine, University of California, San Francisco, CA 94143-0451, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-065X.2008.00758.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248569PMC
March 2009

Generation of a novel system for studying spleen tyrosine kinase function in macrophages and B cells.

J Immunol 2009 Jan;182(2):988-98

Department of Laboratory Medicine, Howard Hughes Medical Institute, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248399PMC
http://dx.doi.org/10.4049/jimmunol.182.2.988DOI Listing
January 2009

Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.

J Leukoc Biol 2008 Oct 14;84(4):1141-50. Epub 2008 Jul 14.

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistr. 15, D-81377 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0208118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538596PMC
October 2008

PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.

J Exp Med 2008 Sep 15;205(10):2339-47. Epub 2008 Sep 15.

Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20072660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556779PMC
September 2008

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.

Blood 2008 Aug 11;112(4):1139-46. Epub 2008 Jun 11.

Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2008-02-140970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515128PMC
August 2008

The diverse functions of Src family kinases in macrophages.

Front Biosci 2008 May 1;13:4426-50. Epub 2008 May 1.

Department of Laboratory Medicine, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457449PMC
http://dx.doi.org/10.2741/3015DOI Listing
May 2008

Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5.

J Clin Invest 2008 Mar;118(3):924-34

Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI34013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214849PMC
March 2008

Immunoreceptor-like signaling by beta 2 and beta 3 integrins.

Trends Cell Biol 2007 Oct;17(10):493-501

Department of Physiology, Semmelweis University School of Medicine, 1088 Budapest, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2007.09.001DOI Listing
October 2007

Convergence of immunoreceptor and integrin signaling.

Immunol Rev 2007 Aug;218:29-44

Department of Laboratory Medicine, University of California, San Francisco, CA 94143-0451, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-065X.2007.00531.xDOI Listing
August 2007

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

Immunity 2007 Jun 31;26(6):773-83. Epub 2007 May 31.

Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S107476130700283
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2007.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600878PMC
June 2007