Claudio Hetz

Claudio Hetz

UNVERIFIED PROFILE

Are you Claudio Hetz?   Register this Author

Register author
Claudio Hetz

Claudio Hetz

Publications by authors named "Claudio Hetz"

Are you Claudio Hetz?   Register this Author

100Publications

3061Reads

34Profile Views

Publisher Correction: Pharmacological targeting of the unfolded protein response for disease intervention.

Nat Chem Biol 2019 Nov;15(11):1129

Orinove Inc., Newbury Park, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41589-019-0363-xDOI Listing
November 2019

The UFMylation System in Proteostasis and Beyond.

Trends Cell Biol 2019 Nov 5. Epub 2019 Nov 5.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago, Chile; FONDAP (Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias) Center for Geroscience (GERO), Brain Health and Metabolism, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Cellular and Molecular Biology Program, Institute of Biomedical Sciences, University of Chile, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2019.09.005DOI Listing
November 2019

β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation.

Neurobiol Dis 2019 10 7;130:104497. Epub 2019 Jun 7.

Neuromuscular Studies Laboratory (NeSt Lab), Center for Advanced Microscopy, Faculty of Biological Sciences, Department of Cell Biology, Universidad de Concepción, Concepción, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2019.104497DOI Listing
October 2019

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.

Cell Death Differ 2019 Oct 7. Epub 2019 Oct 7.

Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-019-0408-4DOI Listing
October 2019

Small Molecules to Improve ER Proteostasis in Disease.

Trends Pharmacol Sci 2019 Sep 31;40(9):684-695. Epub 2019 Jul 31.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago, Chile; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (FONDAP) Center for Geroscience, Brain Health, and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Science, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2019.07.003DOI Listing
September 2019

Pharmacological targeting of the unfolded protein response for disease intervention.

Nat Chem Biol 2019 08 18;15(8):764-775. Epub 2019 Jul 18.

Orinove Inc., Newbury Park, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41589-019-0326-2DOI Listing
August 2019

Targeting of the unfolded protein response (UPR) as therapy for Parkinson's disease.

Biol Cell 2019 Jun 25;111(6):161-168. Epub 2019 Mar 25.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/boc.201800068DOI Listing
June 2019

Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion.

Cancers (Basel) 2019 May 6;11(5). Epub 2019 May 6.

Proteostasis & Cancer Team, Institut National de la Santé Et la Recherche Médicale U1242 Chemistry, Oncogenesis, Stress and Signaling, Université de Rennes, 35042 Rennes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11050631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562633PMC
May 2019

Brain organoids: a next step for humanized Alzheimer's disease models?

Mol Psychiatry 2019 04 7;24(4):474-478. Epub 2019 Jan 7.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-018-0343-7DOI Listing
April 2019

Unraveling the role of motoneuron autophagy in ALS.

Autophagy 2018 13;14(4):733-737. Epub 2018 Mar 13.

a Biomedical Neuroscience Institute (BNI), Faculty of Medicine , University of Chile , Santiago , Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2018.1432327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959335PMC
March 2019

ER stress links aging to sporadic ALS.

Aging (Albany NY) 2019 01;11(1):5-6

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://www.aging-us.com/article/101705/text
Publisher Site
http://dx.doi.org/10.18632/aging.101705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339799PMC
January 2019

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.

J Hepatol 2018 Oct 27;69(4):927-947. Epub 2018 Jun 27.

Université Côte d'Azur, INSERM, U1065, C3M, 06200 Nice, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01688278183216
Publisher Site
http://dx.doi.org/10.1016/j.jhep.2018.06.008DOI Listing
October 2018

ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?

Curr Top Microbiol Immunol 2018 ;414:131-157

Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/82_2017_52DOI Listing
September 2018

ER Proteostasis Control of Neuronal Physiology and Synaptic Function.

Trends Neurosci 2018 09 23;41(9):610-624. Epub 2018 Jun 23.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tins.2018.05.009DOI Listing
September 2018

A new model to study cell-to-cell transfer of αSynuclein in vivo.

Biochem Biophys Res Commun 2018 09 17;503(3):1385-1393. Epub 2018 Jul 17.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Independencia 1027, Santiago, 8380453, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, 8380453, Chile; FONDAP Center for Geroscience, Brain Health and Metabolism (GERO), Independencia 1027, Santiago, 8380453, Chile; Buck Institute for Research on Aging, Novato, CA, 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, 02115, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2018.07.053DOI Listing
September 2018

Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis.

Proc Natl Acad Sci U S A 2018 08 23;115(32):8209-8214. Epub 2018 Jul 23.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile 8380453;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1801109115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094144PMC
August 2018

Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases.

Semin Cancer Biol 2018 06 31;50:42-52. Epub 2018 Jan 31.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; The Buck Institute for Research in Aging, Novato CA 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2018.01.011DOI Listing
June 2018

Gene Therapy Strategies to Restore ER Proteostasis in Disease.

Mol Ther 2018 06 7;26(6):1404-1413. Epub 2018 Apr 7.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard University, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymthe.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986993PMC
June 2018

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease.

Neurobiol Dis 2018 04 31;112:136-148. Epub 2018 Jan 31.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2018.01.004DOI Listing
April 2018

Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.

Neurobiol Aging 2018 04 29;64:123-138. Epub 2017 Dec 29.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism (GERO), Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA; Harvard School of Public Health, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.020DOI Listing
April 2018

ER stress sensing mechanism: Putting off the brake on UPR transducers.

Oncotarget 2018 Apr 13;9(28):19461-19462. Epub 2018 Apr 13.

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health, and Metabolism (GERO), Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.25114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929400PMC
April 2018

A decay of the adaptive capacity of the unfolded protein response exacerbates Alzheimer's disease.

Neurobiol Aging 2018 03 22;63:162-164. Epub 2017 Sep 22.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.012DOI Listing
March 2018

Calcium signaling at the endoplasmic reticulum: fine-tuning stress responses.

Cell Calcium 2018 03 20;70:24-31. Epub 2017 Aug 20.

Center for Geroscience, Brain Health and Metabolism, Faculty of Medicine, University of Chile, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceca.2017.08.004DOI Listing
March 2018

Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease.

FEBS J 2018 03 15;285(6):995-1011. Epub 2017 Dec 15.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.14332DOI Listing
March 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

(off)Targeting UPR signaling: the race toward intervening ER proteostasis.

Expert Opin Ther Targets 2018 02 23;22(2):97-100. Epub 2017 Dec 23.

a Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile , Santiago , Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14728222.2018.1420169DOI Listing
February 2018

The Unfolded Protein Response and Cell Fate Control.

Mol Cell 2018 01 5;69(2):169-181. Epub 2017 Nov 5.

Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Pathology, University of California, San Francisco, San Francisco, CA, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA, USA; UCSF Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.06.017DOI Listing
January 2018

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.

Mol Cell 2018 01;69(2):238-252.e7

Biomedical Neuroscience Institute (BNI), Faculty of Medicine, University of Chile, Santiago 8380453, Chile; Center for Geroscience, Brain Health, and Metabolism (GERO), Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago 8380453, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.12.028DOI Listing
January 2018

Proteostasis disturbance in amyotrophic lateral sclerosis.

Hum Mol Genet 2017 10;26(R2):R91-R104

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddx274DOI Listing
October 2017

Fine-tuning PERK signaling to control cell fate under stress.

Nat Struct Mol Biol 2017 10;24(10):789-790

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile, the Center for Geroscience, Brain Health and Metabolism, Santiago, Chile, and the Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.3478DOI Listing
October 2017

IRE1 signaling exacerbates Alzheimer's disease pathogenesis.

Acta Neuropathol 2017 Sep 24;134(3):489-506. Epub 2017 Mar 24.

Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-017-1694-xDOI Listing
September 2017

BCL-2 family: integrating stress responses at the ER to control cell demise.

Cell Death Differ 2017 09 16;24(9):1478-1487. Epub 2017 Jun 16.

Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cdd.2017.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563989PMC
September 2017

Endoplasmic reticulum proteostasis impairment in aging.

Aging Cell 2017 08 23;16(4):615-623. Epub 2017 Apr 23.

Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506418PMC
August 2017

ER stress and the unfolded protein response in neurodegeneration.

Nat Rev Neurol 2017 Aug 21;13(8):477-491. Epub 2017 Jul 21.

Department of Neurology, Inselspital University Hospital, University of Bern, Freiburgstrasse 16, CH-3010 Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrneurol.2017.99DOI Listing
August 2017

Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis.

Front Mol Neurosci 2017 5;10:216. Epub 2017 Jul 5.

Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of ChileSantiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnmol.2017.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496948PMC
July 2017

Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts.

Brain 2017 06;140(6):1544-1547

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awx107DOI Listing
June 2017

The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetics.

Front Oncol 2017 3;7:55. Epub 2017 Apr 3.

Center for Geroscience, Brain Health and Metabolism, Faculty of Medicine, University of Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2017.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377016PMC
April 2017

Endoplasmic reticulum proteostasis in glioblastoma-From molecular mechanisms to therapeutic perspectives.

Sci Signal 2017 Mar 14;10(470). Epub 2017 Mar 14.

INSERM U1242, Chemistry, Oncogenesis, Stress Signaling, Université de Rennes 1, Rennes 35000, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aal2323DOI Listing
March 2017

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.

Sci Rep 2017 03 23;7:44723. Epub 2017 Mar 23.

Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Houston Medical School, 6431 Fannin St, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep44723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363067PMC
March 2017

The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability.

Neurosci Lett 2017 01 2;636:9-15. Epub 2016 May 2.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago 8380453, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago 8380453, Chile; Center for Geroscience, Brain Health and Metabolism, University of Chile, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2016.04.066DOI Listing
January 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Authors:
Daniel J Klionsky Kotb Abdelmohsen Akihisa Abe Md Joynal Abedin Hagai Abeliovich Abraham Acevedo Arozena Hiroaki Adachi Christopher M Adams Peter D Adams Khosrow Adeli Peter J Adhihetty Sharon G Adler Galila Agam Rajesh Agarwal Manish K Aghi Maria Agnello Patrizia Agostinis Patricia V Aguilar Julio Aguirre-Ghiso Edoardo M Airoldi Slimane Ait-Si-Ali Takahiko Akematsu Emmanuel T Akporiaye Mohamed Al-Rubeai Guillermo M Albaiceta Chris Albanese Diego Albani Matthew L Albert Jesus Aldudo Hana Algül Mehrdad Alirezaei Iraide Alloza Alexandru Almasan Maylin Almonte-Beceril Emad S Alnemri Covadonga Alonso Nihal Altan-Bonnet Dario C Altieri Silvia Alvarez Lydia Alvarez-Erviti Sandro Alves Giuseppina Amadoro Atsuo Amano Consuelo Amantini Santiago Ambrosio Ivano Amelio Amal O Amer Mohamed Amessou Angelika Amon Zhenyi An Frank A Anania Stig U Andersen Usha P Andley Catherine K Andreadi Nathalie Andrieu-Abadie Alberto Anel David K Ann Shailendra Anoopkumar-Dukie Manuela Antonioli Hiroshi Aoki Nadezda Apostolova Saveria Aquila Katia Aquilano Koichi Araki Eli Arama Agustin Aranda Jun Araya Alexandre Arcaro Esperanza Arias Hirokazu Arimoto Aileen R Ariosa Jane L Armstrong Thierry Arnould Ivica Arsov Katsuhiko Asanuma Valerie Askanas Eric Asselin Ryuichiro Atarashi Sally S Atherton Julie D Atkin Laura D Attardi Patrick Auberger Georg Auburger Laure Aurelian Riccardo Autelli Laura Avagliano Maria Laura Avantaggiati Limor Avrahami Suresh Awale Neelam Azad Tiziana Bachetti Jonathan M Backer Dong-Hun Bae Jae-Sung Bae Ok-Nam Bae Soo Han Bae Eric H Baehrecke Seung-Hoon Baek Stephen Baghdiguian Agnieszka Bagniewska-Zadworna Hua Bai Jie Bai Xue-Yuan Bai Yannick Bailly Kithiganahalli Narayanaswamy Balaji Walter Balduini Andrea Ballabio Rena Balzan Rajkumar Banerjee Gábor Bánhegyi Haijun Bao Benoit Barbeau Maria D Barrachina Esther Barreiro Bonnie Bartel Alberto Bartolomé Diane C Bassham Maria Teresa Bassi Robert C Bast Alakananda Basu Maria Teresa Batista Henri Batoko Maurizio Battino Kyle Bauckman Bradley L Baumgarner K Ulrich Bayer Rupert Beale Jean-François Beaulieu George R Beck Christoph Becker J David Beckham Pierre-André Bédard Patrick J Bednarski Thomas J Begley Christian Behl Christian Behrends Georg Mn Behrens Kevin E Behrns Eloy Bejarano Amine Belaid Francesca Belleudi Giovanni Bénard Guy Berchem Daniele Bergamaschi Matteo Bergami Ben Berkhout Laura Berliocchi Amélie Bernard Monique Bernard Francesca Bernassola Anne Bertolotti Amanda S Bess Sébastien Besteiro Saverio Bettuzzi Savita Bhalla Shalmoli Bhattacharyya Sujit K Bhutia Caroline Biagosch Michele Wolfe Bianchi Martine Biard-Piechaczyk Viktor Billes Claudia Bincoletto Baris Bingol Sara W Bird Marc Bitoun Ivana Bjedov Craig Blackstone Lionel Blanc Guillermo A Blanco Heidi Kiil Blomhoff Emilio Boada-Romero Stefan Böckler Marianne Boes Kathleen Boesze-Battaglia Lawrence H Boise Alessandra Bolino Andrea Boman Paolo Bonaldo Matteo Bordi Jürgen Bosch Luis M Botana Joelle Botti German Bou Marina Bouché Marion Bouchecareilh Marie-Josée Boucher Michael E Boulton Sebastien G Bouret Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan Brady Vania Mm Braga Claudio Brancolini Gerhard H Braus José M Bravo-San Pedro Lisa A Brennan Emery H Bresnick Patrick Brest Dave Bridges Marie-Agnès Bringer Marisa Brini Glauber C Brito Bertha Brodin Paul S Brookes Eric J Brown Karen Brown Hal E Broxmeyer Alain Bruhat Patricia Chakur Brum John H Brumell Nicola Brunetti-Pierri Robert J Bryson-Richardson Shilpa Buch Alastair M Buchan Hikmet Budak Dmitry V Bulavin Scott J Bultman Geert Bultynck Vladimir Bumbasirevic Yan Burelle Robert E Burke Margit Burmeister Peter Bütikofer Laura Caberlotto Ken Cadwell Monika Cahova Dongsheng Cai Jingjing Cai Qian Cai Sara Calatayud Nadine Camougrand Michelangelo Campanella Grant R Campbell Matthew Campbell Silvia Campello Robin Candau Isabella Caniggia Lavinia Cantoni Lizhi Cao Allan B Caplan Michele Caraglia Claudio Cardinali Sandra Morais Cardoso Jennifer S Carew Laura A Carleton Cathleen R Carlin Silvia Carloni Sven R Carlsson Didac Carmona-Gutierrez Leticia Am Carneiro Oliana Carnevali Serena Carra Alice Carrier Bernadette Carroll Caty Casas Josefina Casas Giuliana Cassinelli Perrine Castets Susana Castro-Obregon Gabriella Cavallini Isabella Ceccherini Francesco Cecconi Arthur I Cederbaum Valentín Ceña Simone Cenci Claudia Cerella Davide Cervia Silvia Cetrullo Hassan Chaachouay Han-Jung Chae Andrei S Chagin Chee-Yin Chai Gopal Chakrabarti Georgios Chamilos Edmond Yw Chan Matthew Tv Chan Dhyan Chandra Pallavi Chandra Chih-Peng Chang Raymond Chuen-Chung Chang Ta Yuan Chang John C Chatham Saurabh Chatterjee Santosh Chauhan Yongsheng Che Michael E Cheetham Rajkumar Cheluvappa Chun-Jung Chen Gang Chen Guang-Chao Chen Guoqiang Chen Hongzhuan Chen Jeff W Chen Jian-Kang Chen Min Chen Mingzhou Chen Peiwen Chen Qi Chen Quan Chen Shang-Der Chen Si Chen Steve S-L Chen Wei Chen Wei-Jung Chen Wen Qiang Chen Wenli Chen Xiangmei Chen Yau-Hung Chen Ye-Guang Chen Yin Chen Yingyu Chen Yongshun Chen Yu-Jen Chen Yue-Qin Chen Yujie Chen Zhen Chen Zhong Chen Alan Cheng Christopher Hk Cheng Hua Cheng Heesun Cheong Sara Cherry Jason Chesney Chun Hei Antonio Cheung Eric Chevet Hsiang Cheng Chi Sung-Gil Chi Fulvio Chiacchiera Hui-Ling Chiang Roberto Chiarelli Mario Chiariello Marcello Chieppa Lih-Shen Chin Mario Chiong Gigi Nc Chiu Dong-Hyung Cho Ssang-Goo Cho William C Cho Yong-Yeon Cho Young-Seok Cho Augustine Mk Choi Eui-Ju Choi Eun-Kyoung Choi Jayoung Choi Mary E Choi Seung-Il Choi Tsui-Fen Chou Salem Chouaib Divaker Choubey Vinay Choubey Kuan-Chih Chow Kamal Chowdhury Charleen T Chu Tsung-Hsien Chuang Taehoon Chun Hyewon Chung Taijoon Chung Yuen-Li Chung Yong-Joon Chwae Valentina Cianfanelli Roberto Ciarcia Iwona A Ciechomska Maria Rosa Ciriolo Mara Cirone Sofie Claerhout Michael J Clague Joan Clària Peter Gh Clarke Robert Clarke Emilio Clementi Cédric Cleyrat Miriam Cnop Eliana M Coccia Tiziana Cocco Patrice Codogno Jörn Coers Ezra Ew Cohen David Colecchia Luisa Coletto Núria S Coll Emma Colucci-Guyon Sergio Comincini Maria Condello Katherine L Cook Graham H Coombs Cynthia D Cooper J Mark Cooper Isabelle Coppens Maria Tiziana Corasaniti Marco Corazzari Ramon Corbalan Elisabeth Corcelle-Termeau Mario D Cordero Cristina Corral-Ramos Olga Corti Andrea Cossarizza Paola Costelli Safia Costes Susan L Cotman Ana Coto-Montes Sandra Cottet Eduardo Couve Lori R Covey L Ashley Cowart Jeffery S Cox Fraser P Coxon Carolyn B Coyne Mark S Cragg Rolf J Craven Tiziana Crepaldi Jose L Crespo Alfredo Criollo Valeria Crippa Maria Teresa Cruz Ana Maria Cuervo Jose M Cuezva Taixing Cui Pedro R Cutillas Mark J Czaja Maria F Czyzyk-Krzeska Ruben K Dagda Uta Dahmen Chunsun Dai Wenjie Dai Yun Dai Kevin N Dalby Luisa Dalla Valle Guillaume Dalmasso Marcello D'Amelio Markus Damme Arlette Darfeuille-Michaud Catherine Dargemont Victor M Darley-Usmar Srinivasan Dasarathy Biplab Dasgupta Srikanta Dash Crispin R Dass Hazel Marie Davey Lester M Davids David Dávila Roger J Davis Ted M Dawson Valina L Dawson Paula Daza Jackie de Belleroche Paul de Figueiredo Regina Celia Bressan Queiroz de Figueiredo José de la Fuente Luisa De Martino Antonella De Matteis Guido Ry De Meyer Angelo De Milito Mauro De Santi Wanderley de Souza Vincenzo De Tata Daniela De Zio Jayanta Debnath Reinhard Dechant Jean-Paul Decuypere Shane Deegan Benjamin Dehay Barbara Del Bello Dominic P Del Re Régis Delage-Mourroux Lea Md Delbridge Louise Deldicque Elizabeth Delorme-Axford Yizhen Deng Joern Dengjel Melanie Denizot Paul Dent Channing J Der Vojo Deretic Benoît Derrien Eric Deutsch Timothy P Devarenne Rodney J Devenish Sabrina Di Bartolomeo Nicola Di Daniele Fabio Di Domenico Alessia Di Nardo Simone Di Paola Antonio Di Pietro Livia Di Renzo Aaron DiAntonio Guillermo Díaz-Araya Ines Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Chad A Dickey Robert C Dickson Marc Diederich Paul Digard Ivan Dikic Savithrama P Dinesh-Kumar Chan Ding Wen-Xing Ding Zufeng Ding Luciana Dini Jörg Hw Distler Abhinav Diwan Mojgan Djavaheri-Mergny Kostyantyn Dmytruk Renwick Cj Dobson Volker Doetsch Karol Dokladny Svetlana Dokudovskaya Massimo Donadelli X Charlie Dong Xiaonan Dong Zheng Dong Terrence M Donohue Kelly S Doran Gabriella D'Orazi Gerald W Dorn Victor Dosenko Sami Dridi Liat Drucker Jie Du Li-Lin Du Lihuan Du André du Toit Priyamvada Dua Lei Duan Pu Duann Vikash Kumar Dubey Michael R Duchen Michel A Duchosal Helene Duez Isabelle Dugail Verónica I Dumit Mara C Duncan Elaine A Dunlop William A Dunn Nicolas Dupont Luc Dupuis Raúl V Durán Thomas M Durcan Stéphane Duvezin-Caubet Umamaheswar Duvvuri Vinay Eapen Darius Ebrahimi-Fakhari Arnaud Echard Leopold Eckhart Charles L Edelstein Aimee L Edinger Ludwig Eichinger Tobias Eisenberg Avital Eisenberg-Lerner N Tony Eissa Wafik S El-Deiry Victoria El-Khoury Zvulun Elazar Hagit Eldar-Finkelman Chris Jh Elliott Enzo Emanuele Urban Emmenegger Nikolai Engedal Anna-Mart Engelbrecht Simone Engelender Jorrit M Enserink Ralf Erdmann Jekaterina Erenpreisa Rajaraman Eri Jason L Eriksen Andreja Erman Ricardo Escalante Eeva-Liisa Eskelinen Lucile Espert Lorena Esteban-Martínez Thomas J Evans Mario Fabri Gemma Fabrias Cinzia Fabrizi Antonio Facchiano Nils J Færgeman Alberto Faggioni W Douglas Fairlie Chunhai Fan Daping Fan Jie Fan Shengyun Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Mathias Faure Francois B Favier Howard Fearnhead Massimo Federici Erkang Fei Tania C Felizardo Hua Feng Yibin Feng Yuchen Feng Thomas A Ferguson Álvaro F Fernández Maite G Fernandez-Barrena Jose C Fernandez-Checa Arsenio Fernández-López Martin E Fernandez-Zapico Olivier Feron Elisabetta Ferraro Carmen Veríssima Ferreira-Halder Laszlo Fesus Ralph Feuer Fabienne C Fiesel Eduardo C Filippi-Chiela Giuseppe Filomeni Gian Maria Fimia John H Fingert Steven Finkbeiner Toren Finkel Filomena Fiorito Paul B Fisher Marc Flajolet Flavio Flamigni Oliver Florey Salvatore Florio R Andres Floto Marco Folini Carlo Follo Edward A Fon Francesco Fornai Franco Fortunato Alessandro Fraldi Rodrigo Franco Arnaud Francois Aurélie François Lisa B Frankel Iain Dc Fraser Norbert Frey Damien G Freyssenet Christian Frezza Scott L Friedman Daniel E Frigo Dongxu Fu José M Fuentes Juan Fueyo Yoshio Fujitani Yuuki Fujiwara Mikihiro Fujiya Mitsunori Fukuda Simone Fulda Carmela Fusco Bozena Gabryel Matthias Gaestel Philippe Gailly Malgorzata Gajewska Sehamuddin Galadari Gad Galili Inmaculada Galindo Maria F Galindo Giovanna Galliciotti Lorenzo Galluzzi Luca Galluzzi Vincent Galy Noor Gammoh Sam Gandy Anand K Ganesan Swamynathan Ganesan Ian G Ganley Monique Gannagé Fen-Biao Gao Feng Gao Jian-Xin Gao Lorena García Nannig Eleonora García Véscovi Marina Garcia-Macía Carmen Garcia-Ruiz Abhishek D Garg Pramod Kumar Garg Ricardo Gargini Nils Christian Gassen Damián Gatica Evelina Gatti Julie Gavard Evripidis Gavathiotis Liang Ge Pengfei Ge Shengfang Ge Po-Wu Gean Vania Gelmetti Armando A Genazzani Jiefei Geng Pascal Genschik Lisa Gerner Jason E Gestwicki David A Gewirtz Saeid Ghavami Eric Ghigo Debabrata Ghosh Anna Maria Giammarioli Francesca Giampieri Claudia Giampietri Alexandra Giatromanolaki Derrick J Gibbings Lara Gibellini Spencer B Gibson Vanessa Ginet Antonio Giordano Flaviano Giorgini Elisa Giovannetti Stephen E Girardin Suzana Gispert Sandy Giuliano Candece L Gladson Alvaro Glavic Martin Gleave Nelly Godefroy Robert M Gogal Kuppan Gokulan Gustavo H Goldman Delia Goletti Michael S Goligorsky Aldrin V Gomes Ligia C Gomes Hernando Gomez Candelaria Gomez-Manzano Rubén Gómez-Sánchez Dawit Ap Gonçalves Ebru Goncu Qingqiu Gong Céline Gongora Carlos B Gonzalez Pedro Gonzalez-Alegre Pilar Gonzalez-Cabo Rosa Ana González-Polo Ing Swie Goping Carlos Gorbea Nikolai V Gorbunov Daphne R Goring Adrienne M Gorman Sharon M Gorski Sandro Goruppi Shino Goto-Yamada Cecilia Gotor Roberta A Gottlieb Illana Gozes Devrim Gozuacik Yacine Graba Martin Graef Giovanna E Granato Gary Dean Grant Steven Grant Giovanni Luca Gravina Douglas R Green Alexander Greenhough Michael T Greenwood Benedetto Grimaldi Frédéric Gros Charles Grose Jean-Francois Groulx Florian Gruber Paolo Grumati Tilman Grune Jun-Lin Guan Kun-Liang Guan Barbara Guerra Carlos Guillen Kailash Gulshan Jan Gunst Chuanyong Guo Lei Guo Ming Guo Wenjie Guo Xu-Guang Guo Andrea A Gust Åsa B Gustafsson Elaine Gutierrez Maximiliano G Gutierrez Ho-Shin Gwak Albert Haas James E Haber Shinji Hadano Monica Hagedorn David R Hahn Andrew J Halayko Anne Hamacher-Brady Kozo Hamada Ahmed Hamai Andrea Hamann Maho Hamasaki Isabelle Hamer Qutayba Hamid Ester M Hammond Feng Han Weidong Han James T Handa John A Hanover Malene Hansen Masaru Harada Ljubica Harhaji-Trajkovic J Wade Harper Abdel Halim Harrath Adrian L Harris James Harris Udo Hasler Peter Hasselblatt Kazuhisa Hasui Robert G Hawley Teresa S Hawley Congcong He Cynthia Y He Fengtian He Gu He Rong-Rong He Xian-Hui He You-Wen He Yu-Ying He Joan K Heath Marie-Josée Hébert Robert A Heinzen Gudmundur Vignir Helgason Michael Hensel Elizabeth P Henske Chengtao Her Paul K Herman Agustín Hernández Carlos Hernandez Sonia Hernández-Tiedra Claudio Hetz P Robin Hiesinger Katsumi Higaki Sabine Hilfiker Bradford G Hill Joseph A Hill William D Hill Keisuke Hino Daniel Hofius Paul Hofman Günter U Höglinger Jörg Höhfeld Marina K Holz Yonggeun Hong David A Hood Jeroen Jm Hoozemans Thorsten Hoppe Chin Hsu Chin-Yuan Hsu Li-Chung Hsu Dong Hu Guochang Hu Hong-Ming Hu Hongbo Hu Ming Chang Hu Yu-Chen Hu Zhuo-Wei Hu Fang Hua Ya Hua Canhua Huang Huey-Lan Huang Kuo-How Huang Kuo-Yang Huang Shile Huang Shiqian Huang Wei-Pang Huang Yi-Ran Huang Yong Huang Yunfei Huang Tobias B Huber Patricia Huebbe Won-Ki Huh Juha J Hulmi Gang Min Hur James H Hurley Zvenyslava Husak Sabah Na Hussain Salik Hussain Jung Jin Hwang Seungmin Hwang Thomas Is Hwang Atsuhiro Ichihara Yuzuru Imai Carol Imbriano Megumi Inomata Takeshi Into Valentina Iovane Juan L Iovanna Renato V Iozzo Nancy Y Ip Javier E Irazoqui Pablo Iribarren Yoshitaka Isaka Aleksandra J Isakovic Harry Ischiropoulos Jeffrey S Isenberg Mohammad Ishaq Hiroyuki Ishida Isao Ishii Jane E Ishmael Ciro Isidoro Ken-Ichi Isobe Erika Isono Shohreh Issazadeh-Navikas Koji Itahana Eisuke Itakura Andrei I Ivanov Anand Krishnan V Iyer José M Izquierdo Yotaro Izumi Valentina Izzo Marja Jäättelä Nadia Jaber Daniel John Jackson William T Jackson Tony George Jacob Thomas S Jacques Chinnaswamy Jagannath Ashish Jain Nihar Ranjan Jana Byoung Kuk Jang Alkesh Jani Bassam Janji Paulo Roberto Jannig Patric J Jansson Steve Jean Marina Jendrach Ju-Hong Jeon Niels Jessen Eui-Bae Jeung Kailiang Jia Lijun Jia Hong Jiang Hongchi Jiang Liwen Jiang Teng Jiang Xiaoyan Jiang Xuejun Jiang Xuejun Jiang Ying Jiang Yongjun Jiang Alberto Jiménez Cheng Jin Hongchuan Jin Lei Jin Meiyan Jin Shengkan Jin Umesh Kumar Jinwal Eun-Kyeong Jo Terje Johansen Daniel E Johnson Gail Vw Johnson James D Johnson Eric Jonasch Chris Jones Leo Ab Joosten Joaquin Jordan Anna-Maria Joseph Bertrand Joseph Annie M Joubert Dianwen Ju Jingfang Ju Hsueh-Fen Juan Katrin Juenemann Gábor Juhász Hye Seung Jung Jae U Jung Yong-Keun Jung Heinz Jungbluth Matthew J Justice Barry Jutten Nadeem O Kaakoush Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Bertrand Kaeffer Katarina Kågedal Alon Kahana Shingo Kajimura Or Kakhlon Manjula Kalia Dhan V Kalvakolanu Yoshiaki Kamada Konstantinos Kambas Vitaliy O Kaminskyy Harm H Kampinga Mustapha Kandouz Chanhee Kang Rui Kang Tae-Cheon Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Marc Kantorow Maria Kaparakis-Liaskos Orsolya Kapuy Vassiliki Karantza Md Razaul Karim Parimal Karmakar Arthur Kaser Susmita Kaushik Thomas Kawula A Murat Kaynar Po-Yuan Ke Zun-Ji Ke John H Kehrl Kate E Keller Jongsook Kim Kemper Anne K Kenworthy Oliver Kepp Andreas Kern Santosh Kesari David Kessel Robin Ketteler Isis do Carmo Kettelhut Bilon Khambu Muzamil Majid Khan Vinoth Km Khandelwal Sangeeta Khare Juliann G Kiang Amy A Kiger Akio Kihara Arianna L Kim Cheol Hyeon Kim Deok Ryong Kim Do-Hyung Kim Eung Kweon Kim Hye Young Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim Jin Hyoung Kim Kwang Woon Kim Michael D Kim Moon-Moo Kim Peter K Kim Seong Who Kim Soo-Youl Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Tomonori Kimura Jason S King Karla Kirkegaard Vladimir Kirkin Lorrie A Kirshenbaum Shuji Kishi Yasuo Kitajima Katsuhiko Kitamoto Yasushi Kitaoka Kaio Kitazato Rudolf A Kley Walter T Klimecki Michael Klinkenberg Jochen Klucken Helene Knævelsrud Erwin Knecht Laura Knuppertz Jiunn-Liang Ko Satoru Kobayashi Jan C Koch Christelle Koechlin-Ramonatxo Ulrich Koenig Young Ho Koh Katja Köhler Sepp D Kohlwein Masato Koike Masaaki Komatsu Eiki Kominami Dexin Kong Hee Jeong Kong Eumorphia G Konstantakou Benjamin T Kopp Tamas Korcsmaros Laura Korhonen Viktor I Korolchuk Nadya V Koshkina Yanjun Kou Michael I Koukourakis Constantinos Koumenis Attila L Kovács Tibor Kovács Werner J Kovacs Daisuke Koya Claudine Kraft Dimitri Krainc Helmut Kramer Tamara Kravic-Stevovic Wilhelm Krek Carole Kretz-Remy Roswitha Krick Malathi Krishnamurthy Janos Kriston-Vizi Guido Kroemer Michael C Kruer Rejko Kruger Nicholas T Ktistakis Kazuyuki Kuchitsu Christian Kuhn Addanki Pratap Kumar Anuj Kumar Ashok Kumar Deepak Kumar Dhiraj Kumar Rakesh Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Atsushi Kuno Sheng-Han Kuo Jeff Kuret Tino Kurz Terry Kwok Taeg Kyu Kwon Yong Tae Kwon Irene Kyrmizi Albert R La Spada Frank Lafont Tim Lahm Aparna Lakkaraju Truong Lam Trond Lamark Steve Lancel Terry H Landowski Darius J R Lane Jon D Lane Cinzia Lanzi Pierre Lapaquette Louis R Lapierre Jocelyn Laporte Johanna Laukkarinen Gordon W Laurie Sergio Lavandero Lena Lavie Matthew J LaVoie Betty Yuen Kwan Law Helen Ka-Wai Law Kelsey B Law Robert Layfield Pedro A Lazo Laurent Le Cam Karine G Le Roch Hervé Le Stunff Vijittra Leardkamolkarn Marc Lecuit Byung-Hoon Lee Che-Hsin Lee Erinna F Lee Gyun Min Lee He-Jin Lee Hsinyu Lee Jae Keun Lee Jongdae Lee Ju-Hyun Lee Jun Hee Lee Michael Lee Myung-Shik Lee Patty J Lee Sam W Lee Seung-Jae Lee Shiow-Ju Lee Stella Y Lee Sug Hyung Lee Sung Sik Lee Sung-Joon Lee Sunhee Lee Ying-Ray Lee Yong J Lee Young H Lee Christiaan Leeuwenburgh Sylvain Lefort Renaud Legouis Jinzhi Lei Qun-Ying Lei David A Leib Gil Leibowitz Istvan Lekli Stéphane D Lemaire John J Lemasters Marius K Lemberg Antoinette Lemoine Shuilong Leng Guido Lenz Paola Lenzi Lilach O Lerman Daniele Lettieri Barbato Julia I-Ju Leu Hing Y Leung Beth Levine Patrick A Lewis Frank Lezoualc'h Chi Li Faqiang Li Feng-Jun Li Jun Li Ke Li Lian Li Min Li Min Li Qiang Li Rui Li Sheng Li Wei Li Wei Li Xiaotao Li Yumin Li Jiqin Lian Chengyu Liang Qiangrong Liang Yulin Liao Joana Liberal Pawel P Liberski Pearl Lie Andrew P Lieberman Hyunjung Jade Lim Kah-Leong Lim Kyu Lim Raquel T Lima Chang-Shen Lin Chiou-Feng Lin Fang Lin Fangming Lin Fu-Cheng Lin Kui Lin Kwang-Huei Lin Pei-Hui Lin Tianwei Lin Wan-Wan Lin Yee-Shin Lin Yong Lin Rafael Linden Dan Lindholm Lisa M Lindqvist Paul Lingor Andreas Linkermann Lance A Liotta Marta M Lipinski Vitor A Lira Michael P Lisanti Paloma B Liton Bo Liu Chong Liu Chun-Feng Liu Fei Liu Hung-Jen Liu Jianxun Liu Jing-Jing Liu Jing-Lan Liu Ke Liu Leyuan Liu Liang Liu Quentin Liu Rong-Yu Liu Shiming Liu Shuwen Liu Wei Liu Xian-De Liu Xiangguo Liu Xiao-Hong Liu Xinfeng Liu Xu Liu Xueqin Liu Yang Liu Yule Liu Zexian Liu Zhe Liu Juan P Liuzzi Gérard Lizard Mila Ljujic Irfan J Lodhi Susan E Logue Bal L Lokeshwar Yun Chau Long Sagar Lonial Benjamin Loos Carlos López-Otín Cristina López-Vicario Mar Lorente Philip L Lorenzi Péter Lõrincz Marek Los Michael T Lotze Penny E Lovat Binfeng Lu Bo Lu Jiahong Lu Qing Lu She-Min Lu Shuyan Lu Yingying Lu Frédéric Luciano Shirley Luckhart John Milton Lucocq Paula Ludovico Aurelia Lugea Nicholas W Lukacs Julian J Lum Anders H Lund Honglin Luo Jia Luo Shouqing Luo Claudio Luparello Timothy Lyons Jianjie Ma Yi Ma Yong Ma Zhenyi Ma Juliano Machado Glaucia M Machado-Santelli Fernando Macian Gustavo C MacIntosh Jeffrey P MacKeigan Kay F Macleod John D MacMicking Lee Ann MacMillan-Crow Frank Madeo Muniswamy Madesh Julio Madrigal-Matute Akiko Maeda Tatsuya Maeda Gustavo Maegawa Emilia Maellaro Hannelore Maes Marta Magariños Kenneth Maiese Tapas K Maiti Luigi Maiuri Maria Chiara Maiuri Carl G Maki Roland Malli Walter Malorni Alina Maloyan Fathia Mami-Chouaib Na Man Joseph D Mancias Eva-Maria Mandelkow Michael A Mandell Angelo A Manfredi Serge N Manié Claudia Manzoni Kai Mao Zixu Mao Zong-Wan Mao Philippe Marambaud Anna Maria Marconi Zvonimir Marelja Gabriella Marfe Marta Margeta Eva Margittai Muriel Mari Francesca V Mariani Concepcio Marin Sara Marinelli Guillermo Mariño Ivanka Markovic Rebecca Marquez Alberto M Martelli Sascha Martens Katie R Martin Seamus J Martin Shaun Martin Miguel A Martin-Acebes Paloma Martín-Sanz Camille Martinand-Mari Wim Martinet Jennifer Martinez Nuria Martinez-Lopez Ubaldo Martinez-Outschoorn Moisés Martínez-Velázquez Marta Martinez-Vicente Waleska Kerllen Martins Hirosato Mashima James A Mastrianni Giuseppe Matarese Paola Matarrese Roberto Mateo Satoaki Matoba Naomichi Matsumoto Takehiko Matsushita Akira Matsuura Takeshi Matsuzawa Mark P Mattson Soledad Matus Norma Maugeri Caroline Mauvezin Andreas Mayer Dusica Maysinger Guillermo D Mazzolini Mary Kate McBrayer Kimberly McCall Craig McCormick Gerald M McInerney Skye C McIver Sharon McKenna John J McMahon Iain A McNeish Fatima Mechta-Grigoriou Jan Paul Medema Diego L Medina Klara Megyeri Maryam Mehrpour Jawahar L Mehta Yide Mei Ute-Christiane Meier Alfred J Meijer Alicia Meléndez Gerry Melino Sonia Melino Edesio Jose Tenorio de Melo Maria A Mena Marc D Meneghini Javier A Menendez Regina Menezes Liesu Meng Ling-Hua Meng Songshu Meng Rossella Menghini A Sue Menko Rubem Fs Menna-Barreto Manoj B Menon Marco A Meraz-Ríos Giuseppe Merla Luciano Merlini Angelica M Merlot Andreas Meryk Stefania Meschini Joel N Meyer Man-Tian Mi Chao-Yu Miao Lucia Micale Simon Michaeli Carine Michiels Anna Rita Migliaccio Anastasia Susie Mihailidou Dalibor Mijaljica Katsuhiko Mikoshiba Enrico Milan Leonor Miller-Fleming Gordon B Mills Ian G Mills Georgia Minakaki Berge A Minassian Xiu-Fen Ming Farida Minibayeva Elena A Minina Justine D Mintern Saverio Minucci Antonio Miranda-Vizuete Claire H Mitchell Shigeki Miyamoto Keisuke Miyazawa Noboru Mizushima Katarzyna Mnich Baharia Mograbi Simin Mohseni Luis Ferreira Moita Marco Molinari Maurizio Molinari Andreas Buch Møller Bertrand Mollereau Faustino Mollinedo Marco Mongillo Martha M Monick Serena Montagnaro Craig Montell Darren J Moore Michael N Moore Rodrigo Mora-Rodriguez Paula I Moreira Etienne Morel Maria Beatrice Morelli Sandra Moreno Michael J Morgan Arnaud Moris Yuji Moriyasu Janna L Morrison Lynda A Morrison Eugenia Morselli Jorge Moscat Pope L Moseley Serge Mostowy Elisa Motori Denis Mottet Jeremy C Mottram Charbel E-H Moussa Vassiliki E Mpakou Hasan Mukhtar Jean M Mulcahy Levy Sylviane Muller Raquel Muñoz-Moreno Cristina Muñoz-Pinedo Christian Münz Maureen E Murphy James T Murray Aditya Murthy Indira U Mysorekar Ivan R Nabi Massimo Nabissi Gustavo A Nader Yukitoshi Nagahara Yoshitaka Nagai Kazuhiro Nagata Anika Nagelkerke Péter Nagy Samisubbu R Naidu Sreejayan Nair Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Gennaro Napolitano Naweed I Naqvi Roberta Nardacci Derek P Narendra Masashi Narita Anna Chiara Nascimbeni Ramesh Natarajan Luiz C Navegantes Steffan T Nawrocki Taras Y Nazarko Volodymyr Y Nazarko Thomas Neill Luca M Neri Mihai G Netea Romana T Netea-Maier Bruno M Neves Paul A Ney Ioannis P Nezis Hang Tt Nguyen Huu Phuc Nguyen Anne-Sophie Nicot Hilde Nilsen Per Nilsson Mikio Nishimura Ichizo Nishino Mireia Niso-Santano Hua Niu Ralph A Nixon Vincent Co Njar Takeshi Noda Angelika A Noegel Elsie Magdalena Nolte Erik Norberg Koenraad K Norga Sakineh Kazemi Noureini Shoji Notomi Lucia Notterpek Karin Nowikovsky Nobuyuki Nukina Thorsten Nürnberger Valerie B O'Donnell Tracey O'Donovan Peter J O'Dwyer Ina Oehme Clara L Oeste Michinaga Ogawa Besim Ogretmen Yuji Ogura Young J Oh Masaki Ohmuraya Takayuki Ohshima Rani Ojha Koji Okamoto Toshiro Okazaki F Javier Oliver Karin Ollinger Stefan Olsson Daniel P Orban Paulina Ordonez Idil Orhon Laszlo Orosz Eyleen J O'Rourke Helena Orozco Angel L Ortega Elena Ortona Laura D Osellame Junko Oshima Shigeru Oshima Heinz D Osiewacz Takanobu Otomo Kinya Otsu Jing-Hsiung James Ou Tiago F Outeiro Dong-Yun Ouyang Hongjiao Ouyang Michael Overholtzer Michelle A Ozbun P Hande Ozdinler Bulent Ozpolat Consiglia Pacelli Paolo Paganetti Guylène Page Gilles Pages Ugo Pagnini Beata Pajak Stephen C Pak Karolina Pakos-Zebrucka Nazzy Pakpour Zdena Palková Francesca Palladino Kathrin Pallauf Nicolas Pallet Marta Palmieri Søren R Paludan Camilla Palumbo Silvia Palumbo Olatz Pampliega Hongming Pan Wei Pan Theocharis Panaretakis Aseem Pandey Areti Pantazopoulou Zuzana Papackova Daniela L Papademetrio Issidora Papassideri Alessio Papini Nirmala Parajuli Julian Pardo Vrajesh V Parekh Giancarlo Parenti Jong-In Park Junsoo Park Ohkmae K Park Roy Parker Rosanna Parlato Jan B Parys Katherine R Parzych Jean-Max Pasquet Benoit Pasquier Kishore Bs Pasumarthi Daniel Patschan Cam Patterson Sophie Pattingre Scott Pattison Arnim Pause Hermann Pavenstädt Flaminia Pavone Zully Pedrozo Fernando J Peña Miguel A Peñalva Mario Pende Jianxin Peng Fabio Penna Josef M Penninger Anna Pensalfini Salvatore Pepe Gustavo Js Pereira Paulo C Pereira Verónica Pérez-de la Cruz María Esther Pérez-Pérez Diego Pérez-Rodríguez Dolores Pérez-Sala Celine Perier Andras Perl David H Perlmutter Ida Perrotta Shazib Pervaiz Maija Pesonen Jeffrey E Pessin Godefridus J Peters Morten Petersen Irina Petrache Basil J Petrof Goran Petrovski James M Phang Mauro Piacentini Marina Pierdominici Philippe Pierre Valérie Pierrefite-Carle Federico Pietrocola Felipe X Pimentel-Muiños Mario Pinar Benjamin Pineda Ronit Pinkas-Kramarski Marcello Pinti Paolo Pinton Bilal Piperdi James M Piret Leonidas C Platanias Harald W Platta Edward D Plowey Stefanie Pöggeler Marc Poirot Peter Polčic Angelo Poletti Audrey H Poon Hana Popelka Blagovesta Popova Izabela Poprawa Shibu M Poulose Joanna Poulton Scott K Powers Ted Powers Mercedes Pozuelo-Rubio Krisna Prak Reinhild Prange Mark Prescott Muriel Priault Sharon Prince Richard L Proia Tassula Proikas-Cezanne Holger Prokisch Vasilis J Promponas Karin Przyklenk Rosa Puertollano Subbiah Pugazhenthi Luigi Puglielli Aurora Pujol Julien Puyal Dohun Pyeon Xin Qi Wen-Bin Qian Zheng-Hong Qin Yu Qiu Ziwei Qu Joe Quadrilatero Frederick Quinn Nina Raben Hannah Rabinowich Flavia Radogna Michael J Ragusa Mohamed Rahmani Komal Raina Sasanka Ramanadham Rajagopal Ramesh Abdelhaq Rami Sarron Randall-Demllo Felix Randow Hai Rao V Ashutosh Rao Blake B Rasmussen Tobias M Rasse Edward A Ratovitski Pierre-Emmanuel Rautou Swapan K Ray Babak Razani Bruce H Reed Fulvio Reggiori Markus Rehm Andreas S Reichert Theo Rein David J Reiner Eric Reits Jun Ren Xingcong Ren Maurizio Renna Jane Eb Reusch Jose L Revuelta Leticia Reyes Alireza R Rezaie Robert I Richards Des R Richardson Clémence Richetta Michael A Riehle Bertrand H Rihn Yasuko Rikihisa Brigit E Riley Gerald Rimbach Maria Rita Rippo Konstantinos Ritis Federica Rizzi Elizete Rizzo Peter J Roach Jeffrey Robbins Michel Roberge Gabriela Roca Maria Carmela Roccheri Sonia Rocha Cecilia Mp Rodrigues Clara I Rodríguez Santiago Rodriguez de Cordoba Natalia Rodriguez-Muela Jeroen Roelofs Vladimir V Rogov Troy T Rohn Bärbel Rohrer Davide Romanelli Luigina Romani Patricia Silvia Romano M Isabel G Roncero Jose Luis Rosa Alicia Rosello Kirill V Rosen Philip Rosenstiel Magdalena Rost-Roszkowska Kevin A Roth Gael Roué Mustapha Rouis Kasper M Rouschop Daniel T Ruan Diego Ruano David C Rubinsztein Edmund B Rucker Assaf Rudich Emil Rudolf Ruediger Rudolf Markus A Ruegg Carmen Ruiz-Roldan Avnika Ashok Ruparelia Paola Rusmini David W Russ Gian Luigi Russo Giuseppe Russo Rossella Russo Tor Erik Rusten Victoria Ryabovol Kevin M Ryan Stefan W Ryter David M Sabatini Michael Sacher Carsten Sachse Michael N Sack Junichi Sadoshima Paul Saftig Ronit Sagi-Eisenberg Sumit Sahni Pothana Saikumar Tsunenori Saito Tatsuya Saitoh Koichi Sakakura Machiko Sakoh-Nakatogawa Yasuhito Sakuraba María Salazar-Roa Paolo Salomoni Ashok K Saluja Paul M Salvaterra Rosa Salvioli Afshin Samali Anthony Mj Sanchez José A Sánchez-Alcázar Ricardo Sanchez-Prieto Marco Sandri Miguel A Sanjuan Stefano Santaguida Laura Santambrogio Giorgio Santoni Claudia Nunes Dos Santos Shweta Saran Marco Sardiello Graeme Sargent Pallabi Sarkar Sovan Sarkar Maria Rosa Sarrias Minnie M Sarwal Chihiro Sasakawa Motoko Sasaki Miklos Sass Ken Sato Miyuki Sato Joseph Satriano Niramol Savaraj Svetlana Saveljeva Liliana Schaefer Ulrich E Schaible Michael Scharl Hermann M Schatzl Randy Schekman Wiep Scheper Alfonso Schiavi Hyman M Schipper Hana Schmeisser Jens Schmidt Ingo Schmitz Bianca E Schneider E Marion Schneider Jaime L Schneider Eric A Schon Miriam J Schönenberger Axel H Schönthal Daniel F Schorderet Bernd Schröder Sebastian Schuck Ryan J Schulze Melanie Schwarten Thomas L Schwarz Sebastiano Sciarretta Kathleen Scotto A Ivana Scovassi Robert A Screaton Mark Screen Hugo Seca Simon Sedej Laura Segatori Nava Segev Per O Seglen Jose M Seguí-Simarro Juan Segura-Aguilar Ekihiro Seki Christian Sell Iban Seiliez Clay F Semenkovich Gregg L Semenza Utpal Sen Andreas L Serra Ana Serrano-Puebla Hiromi Sesaki Takao Setoguchi Carmine Settembre John J Shacka Ayesha N Shajahan-Haq Irving M Shapiro Shweta Sharma Hua She C-K James Shen Chiung-Chyi Shen Han-Ming Shen Sanbing Shen Weili Shen Rui Sheng Xianyong Sheng Zu-Hang Sheng Trevor G Shepherd Junyan Shi Qiang Shi Qinghua Shi Yuguang Shi Shusaku Shibutani Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Dong Wook Shin Mari L Shinohara Michiko Shintani Takahiro Shintani Tetsuo Shioi Ken Shirabe Ronit Shiri-Sverdlov Orian Shirihai Gordon C Shore Chih-Wen Shu Deepak Shukla Andriy A Sibirny Valentina Sica Christina J Sigurdson Einar M Sigurdsson Puran Singh Sijwali Beata Sikorska Wilian A Silveira Sandrine Silvente-Poirot Gary A Silverman Jan Simak Thomas Simmet Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Matias Simons Anne Simonsen Rajat Singh Shivendra V Singh Shrawan K Singh Debasish Sinha Sangita Sinha Frank A Sinicrope Agnieszka Sirko Kapil Sirohi Balindiwe Jn Sishi Annie Sittler Parco M Siu Efthimios Sivridis Anna Skwarska Ruth Slack Iva Slaninová Nikolai Slavov Soraya S Smaili Keiran Sm Smalley Duncan R Smith Stefaan J Soenen Scott A Soleimanpour Anita Solhaug Kumaravel Somasundaram Jin H Son Avinash Sonawane Chunjuan Song Fuyong Song Hyun Kyu Song Ju-Xian Song Wei Song Kai Y Soo Anil K Sood Tuck Wah Soong Virawudh Soontornniyomkij Maurizio Sorice Federica Sotgia David R Soto-Pantoja Areechun Sotthibundhu Maria João Sousa Herman P Spaink Paul N Span Anne Spang Janet D Sparks Peter G Speck Stephen A Spector Claudia D Spies Wolfdieter Springer Daret St Clair Alessandra Stacchiotti Bart Staels Michael T Stang Daniel T Starczynowski Petro Starokadomskyy Clemens Steegborn John W Steele Leonidas Stefanis Joan Steffan Christine M Stellrecht Harald Stenmark Tomasz M Stepkowski Stęphan T Stern Craig Stevens Brent R Stockwell Veronika Stoka Zuzana Storchova Björn Stork Vassilis Stratoulias Dimitrios J Stravopodis Pavel Strnad Anne Marie Strohecker Anna-Lena Ström Per Stromhaug Jiri Stulik Yu-Xiong Su Zhaoliang Su Carlos S Subauste Srinivasa Subramaniam Carolyn M Sue Sang Won Suh Xinbing Sui Supawadee Sukseree David Sulzer Fang-Lin Sun Jiaren Sun Jun Sun Shi-Yong Sun Yang Sun Yi Sun Yingjie Sun Vinod Sundaramoorthy Joseph Sung Hidekazu Suzuki Kuninori Suzuki Naoki Suzuki Tadashi Suzuki Yuichiro J Suzuki Michele S Swanson Charles Swanton Karl Swärd Ghanshyam Swarup Sean T Sweeney Paul W Sylvester Zsuzsanna Szatmari Eva Szegezdi Peter W Szlosarek Heinrich Taegtmeyer Marco Tafani Emmanuel Taillebourg Stephen Wg Tait Krisztina Takacs-Vellai Yoshinori Takahashi Szabolcs Takáts Genzou Takemura Nagio Takigawa Nicholas J Talbot Elena Tamagno Jerome Tamburini Cai-Ping Tan Lan Tan Mei Lan Tan Ming Tan Yee-Joo Tan Keiji Tanaka Masaki Tanaka Daolin Tang Dingzhong Tang Guomei Tang Isei Tanida Kunikazu Tanji Bakhos A Tannous Jose A Tapia Inmaculada Tasset-Cuevas Marc Tatar Iman Tavassoly Nektarios Tavernarakis Allen Taylor Graham S Taylor Gregory A Taylor J Paul Taylor Mark J Taylor Elena V Tchetina Andrew R Tee Fatima Teixeira-Clerc Sucheta Telang Tewin Tencomnao Ba-Bie Teng Ru-Jeng Teng Faraj Terro Gianluca Tettamanti Arianne L Theiss Anne E Theron Kelly Jean Thomas Marcos P Thomé Paul G Thomes Andrew Thorburn Jeremy Thorner Thomas Thum Michael Thumm Teresa Lm Thurston Ling Tian Andreas Till Jenny Pan-Yun Ting Vladimir I Titorenko Lilach Toker Stefano Toldo Sharon A Tooze Ivan Topisirovic Maria Lyngaas Torgersen Liliana Torosantucci Alicia Torriglia Maria Rosaria Torrisi Cathy Tournier Roberto Towns Vladimir Trajkovic Leonardo H Travassos Gemma Triola Durga Nand Tripathi Daniela Trisciuoglio Rodrigo Troncoso Ioannis P Trougakos Anita C Truttmann Kuen-Jer Tsai Mario P Tschan Yi-Hsin Tseng Takayuki Tsukuba Allan Tsung Andrey S Tsvetkov Shuiping Tu Hsing-Yu Tuan Marco Tucci David A Tumbarello Boris Turk Vito Turk Robin Fb Turner Anders A Tveita Suresh C Tyagi Makoto Ubukata Yasuo Uchiyama Andrej Udelnow Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Benjamin R Underwood Christian Ungermann Rodrigo P Ureshino Ryo Ushioda Vladimir N Uversky Néstor L Uzcátegui Thomas Vaccari Maria I Vaccaro Libuše Váchová Helin Vakifahmetoglu-Norberg Rut Valdor Enza Maria Valente Francois Vallette Angela M Valverde Greet Van den Berghe Ludo Van Den Bosch Gijs R van den Brink F Gisou van der Goot Ida J van der Klei Luc Jw van der Laan Wouter G van Doorn Marjolein van Egmond Kenneth L van Golen Luc Van Kaer Menno van Lookeren Campagne Peter Vandenabeele Wim Vandenberghe Ilse Vanhorebeek Isabel Varela-Nieto M Helena Vasconcelos Radovan Vasko Demetrios G Vavvas Ignacio Vega-Naredo Guillermo Velasco Athanassios D Velentzas Panagiotis D Velentzas Tibor Vellai Edo Vellenga Mikkel Holm Vendelbo Kartik Venkatachalam Natascia Ventura Salvador Ventura Patrícia St Veras Mireille Verdier Beata G Vertessy Andrea Viale Michel Vidal Helena L A Vieira Richard D Vierstra Nadarajah Vigneswaran Neeraj Vij Miquel Vila Margarita Villar Victor H Villar Joan Villarroya Cécile Vindis Giampietro Viola Maria Teresa Viscomi Giovanni Vitale Dan T Vogl Olga V Voitsekhovskaja Clarissa von Haefen Karin von Schwarzenberg Daniel E Voth Valérie Vouret-Craviari Kristina Vuori Jatin M Vyas Christian Waeber Cheryl Lyn Walker Mark J Walker Jochen Walter Lei Wan Xiangbo Wan Bo Wang Caihong Wang Chao-Yung Wang Chengshu Wang Chenran Wang Chuangui Wang Dong Wang Fen Wang Fuxin Wang Guanghui Wang Hai-Jie Wang Haichao Wang Hong-Gang Wang Hongmin Wang Horng-Dar Wang Jing Wang Junjun Wang Mei Wang Mei-Qing Wang Pei-Yu Wang Peng Wang Richard C Wang Shuo Wang Ting-Fang Wang Xian Wang Xiao-Jia Wang Xiao-Wei Wang Xin Wang Xuejun Wang Yan Wang Yanming Wang Ying Wang Ying-Jan Wang Yipeng Wang Yu Wang Yu Tian Wang Yuqing Wang Zhi-Nong Wang Pablo Wappner Carl Ward Diane McVey Ward Gary Warnes Hirotaka Watada Yoshihisa Watanabe Kei Watase Timothy E Weaver Colin D Weekes Jiwu Wei Thomas Weide Conrad C Weihl Günther Weindl Simone Nardin Weis Longping Wen Xin Wen Yunfei Wen Benedikt Westermann Cornelia M Weyand Anthony R White Eileen White J Lindsay Whitton Alexander J Whitworth Joëlle Wiels Franziska Wild Manon E Wildenberg Tom Wileman Deepti Srinivas Wilkinson Simon Wilkinson Dieter Willbold Chris Williams Katherine Williams Peter R Williamson Konstanze F Winklhofer Steven S Witkin Stephanie E Wohlgemuth Thomas Wollert Ernst J Wolvetang Esther Wong G William Wong Richard W Wong Vincent Kam Wai Wong Elizabeth A Woodcock Karen L Wright Chunlai Wu Defeng Wu Gen Sheng Wu Jian Wu Junfang Wu Mian Wu Min Wu Shengzhou Wu William Kk Wu Yaohua Wu Zhenlong Wu Cristina Pr Xavier Ramnik J Xavier Gui-Xian Xia Tian Xia Weiliang Xia Yong Xia Hengyi Xiao Jian Xiao Shi Xiao Wuhan Xiao Chuan-Ming Xie Zhiping Xie Zhonglin Xie Maria Xilouri Yuyan Xiong Chuanshan Xu Congfeng Xu Feng Xu Haoxing Xu Hongwei Xu Jian Xu Jianzhen Xu Jinxian Xu Liang Xu Xiaolei Xu Yangqing Xu Ye Xu Zhi-Xiang Xu Ziheng Xu Yu Xue Takahiro Yamada Ai Yamamoto Koji Yamanaka Shunhei Yamashina Shigeko Yamashiro Bing Yan Bo Yan Xianghua Yan Zhen Yan Yasuo Yanagi Dun-Sheng Yang Jin-Ming Yang Liu Yang Minghua Yang Pei-Ming Yang Peixin Yang Qian Yang Wannian Yang Wei Yuan Yang Xuesong Yang Yi Yang Ying Yang Zhifen Yang Zhihong Yang Meng-Chao Yao Pamela J Yao Xiaofeng Yao Zhenyu Yao Zhiyuan Yao Linda S Yasui Mingxiang Ye Barry Yedvobnick Behzad Yeganeh Elizabeth S Yeh Patricia L Yeyati Fan Yi Long Yi Xiao-Ming Yin Calvin K Yip Yeong-Min Yoo Young Hyun Yoo Seung-Yong Yoon Ken-Ichi Yoshida Tamotsu Yoshimori Ken H Young Huixin Yu Jane J Yu Jin-Tai Yu Jun Yu Li Yu W Haung Yu Xiao-Fang Yu Zhengping Yu Junying Yuan Zhi-Min Yuan Beatrice Yjt Yue Jianbo Yue Zhenyu Yue David N Zacks Eldad Zacksenhaus Nadia Zaffaroni Tania Zaglia Zahra Zakeri Vincent Zecchini Jinsheng Zeng Min Zeng Qi Zeng Antonis S Zervos Donna D Zhang Fan Zhang Guo Zhang Guo-Chang Zhang Hao Zhang Hong Zhang Hong Zhang Hongbing Zhang Jian Zhang Jian Zhang Jiangwei Zhang Jianhua Zhang Jing-Pu Zhang Li Zhang Lin Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xiangnan Zhang Xu Dong Zhang Yan Zhang Yang Zhang Yanjin Zhang Yingmei Zhang Yunjiao Zhang Mei Zhao Wei-Li Zhao Xiaonan Zhao Yan G Zhao Ying Zhao Yongchao Zhao Yu-Xia Zhao Zhendong Zhao Zhizhuang J Zhao Dexian Zheng Xi-Long Zheng Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Guang-Zhou Zhou Guofei Zhou Huiping Zhou Shu-Feng Zhou Xu-Jie Zhou Hongxin Zhu Hua Zhu Wei-Guo Zhu Wenhua Zhu Xiao-Feng Zhu Yuhua Zhu Shi-Mei Zhuang Xiaohong Zhuang Elio Ziparo Christos E Zois Teresa Zoladek Wei-Xing Zong Antonio Zorzano Susu M Zughaier

Autophagy 2016 ;12(1):1-222

kb Emory University, School of Medicine , Department of Microbiology and Immunology , Atlanta , GA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2015.1100356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835977PMC
October 2016

The intersection between growth factors, autophagy and ER stress: A new target to treat neurodegenerative diseases?

Brain Res 2016 Oct 18;1649(Pt B):173-180. Epub 2016 Mar 18.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; FONDAP Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Neurounion Biomedical Foundation, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2016.02.052DOI Listing
October 2016

Injury to the nervous system: A look into the ER.

Brain Res 2016 10 23;1648(Pt B):617-625. Epub 2016 Apr 23.

Geroscience Center for Brain Health and Metabolism, Santiago, Chile; Center for Integrative Biology, Universidad Mayor, Santiago, Chile; Millennium Nucleus for Regenerative Biology, Faculty of Biology, Pontificia Universidad Católica de Chile, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2016.04.053DOI Listing
October 2016

Gene therapy to target ER stress in brain diseases.

Brain Res 2016 10 27;1648(Pt B):561-570. Epub 2016 Apr 27.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA; Department of Immunology and Infectious diseases, Harvard School of Public Health, 02115 Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2016.04.064DOI Listing
October 2016

PREFACE: Divergent roles of ER stress in neurodegeneration and brain disorders.

Brain Res 2016 10 30;1648(Pt B):527-529. Epub 2016 Sep 30.

Institute of Cell Biology, University of Bern, Baltzerstrasse 4, CH-3012 Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2016.09.014DOI Listing
October 2016

Glucose Metabolism: A Sweet Relief of Alzheimer's Disease.

Curr Biol 2016 09;26(17):R806-9

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA 94945, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2016.07.060DOI Listing
September 2016

Commentary: XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity.

Front Aging Neurosci 2016 3;8:182. Epub 2016 Aug 3.

Center for Geroscience, Brain Health and MetabolismSantiago, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of ChileSantiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of ChileSantiago, Chile; Buck Institute for Research on AgingNovato, CA, USA; Department of Immunology and Infectious diseases, Harvard School of Public HealthBoston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnagi.2016.00182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971125PMC
August 2016

NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation.

Mol Biol Cell 2016 06 13;27(11):1712-27. Epub 2016 Apr 13.

Université de Lyon, 69622 Lyon, France CNRS, UMR 5310, INSERM U1217, Institut NeuroMyoGène, Université Lyon 1, 69100 Villeurbanne, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E15-12-0835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884063PMC
June 2016

Bursting the unfolded protein response accelerates axonal regeneration.

Neural Regen Res 2016 Jun;11(6):892-3

Geroscience Center for Brain Health and Metabolism, Santiago, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, 94945, USA; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1673-5374.184453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962573PMC
June 2016

[Creutzfeldt-Jakob disease: Report of one case].

Rev Med Chil 2016 Jun;144(6):796-806

Biomedical Neuroscience Institute, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4067/S0034-98872016000600016DOI Listing
June 2016

Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.

PLoS One 2015 11;10(9):e0136620. Epub 2015 Sep 11.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Department of Immunology and Infectious diseases, Harvard School of Public Health, Boston MA, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136620PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567344PMC
May 2016

Endoplasmic Reticulum Stress and the Hallmarks of Cancer.

Trends Cancer 2016 05 23;2(5):252-262. Epub 2016 Apr 23.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA; Buck Institute for Research on Aging, Novato, CA 94945, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trecan.2016.03.007DOI Listing
May 2016

Targeting the unfolded protein response for disease intervention.

Expert Opin Ther Targets 2015 13;19(9):1203-18. Epub 2015 Jul 13.

University of Chile, Biomedical Neuroscience Institute, Faculty of Medicine , Santiago , Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2015.1053869DOI Listing
April 2016

ALS-linked protein disulfide isomerase variants cause motor dysfunction.

EMBO J 2016 Apr 11;35(8):845-65. Epub 2016 Feb 11.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile Center for Geroscience, Brain Health and Metabolism, Santiago, Chile Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201592224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972141PMC
April 2016

Targeting endoplasmic reticulum acetylation to restore proteostasis in Alzheimer's disease.

Brain 2016 Mar;139(Pt 3):650-2

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile FONDAP Centre for Geroscience, Brain Health and Metabolism, Santiago, Chile Program of Cellular and Molecular Biology, Centre for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awv401DOI Listing
March 2016

Regulation of Memory Formation by the Transcription Factor XBP1.

Cell Rep 2016 Feb 4;14(6):1382-1394. Epub 2016 Feb 4.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.01.028DOI Listing
February 2016

Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport.

Sci Signal 2016 Feb 23;9(416):fs2. Epub 2016 Feb 23.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile. Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile. Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aaf1937DOI Listing
February 2016

ERp57 in neurodegeneration and regeneration.

Neural Regen Res 2016 Feb;11(2):232-3

Neurounion Biomedical Foundation, CENPAR, Santiago, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1673-5374.177722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810980PMC
February 2016

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response.

Sci Rep 2015 Dec 17;5:18304. Epub 2015 Dec 17.

Discipline of Pathology, School of medicine, Clinical Science Institute, National University of Ireland Galway, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep18304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682135PMC
December 2015

Peroxisomes Get Loud: A Redox Antidote to Hearing Loss.

Cell 2015 Nov;163(4):790-1

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile; FONDAP Center for Geroscience, Brain Health and Metabolism, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.10.060DOI Listing
November 2015

ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disorders.

Virus Res 2015 Sep 31;207:69-75. Epub 2014 Dec 31.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Neurounion Biomedical Foundation, Santiago, Chile; Harvard School of Public Health, Boston, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virusres.2014.12.018DOI Listing
September 2015

The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein.

J Biol Chem 2015 Sep 13;290(39):23631-45. Epub 2015 Jul 13.

From the Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago 8380453, Chile, the Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago 8380453, Chile, the Harvard School of Public Health, Boston, Massachusetts 02115

View Article

Download full-text PDF

Source
http://www.jbc.org/content/290/39/23631.full.pdf
Web Search
http://www.jbc.org/lookup/doi/10.1074/jbc.M114.635565
Publisher Site
http://dx.doi.org/10.1074/jbc.M114.635565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583042PMC
September 2015

ER proteostasis addiction in cancer biology: Novel concepts.

Semin Cancer Biol 2015 Aug 27;33:40-7. Epub 2015 Apr 27.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, Faculty of Medicine, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2015.04.003DOI Listing
August 2015

Theme Series--UPR in cancer.

Semin Cancer Biol 2015 Aug 6;33:1-2. Epub 2015 May 6.

ER440 "Oncogenesis, Stress & Signaling", University of Rennes 1, F-35000, France; Centre de Lutte Contre le Cancer Eugène Marquis, F-35000 Rennes, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2015.04.008DOI Listing
August 2015

Proteostasis control by the unfolded protein response.

Nat Cell Biol 2015 Jul;17(7):829-38

Department of Pathology, Diabetes Center, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb3184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546321PMC
July 2015

Gene therapy in Parkinson's disease: targeting the endplasmic reticulum proteostasis network.

Neural Regen Res 2015 Jul;10(7):1053-4

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile ; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile ; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1673-5374.160077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541229PMC
July 2015

Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis.

Cancer Discov 2015 Jun 14;5(6):586-97. Epub 2015 May 14.

Apoptosis Research Centre, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-14-1490DOI Listing
June 2015

RNA metabolism: putting the brake on the UPR.

EMBO Rep 2015 May 25;16(5):545-6. Epub 2015 Mar 25.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile Department of Immunology and Infectious diseases, Harvard School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201540227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428039PMC
May 2015

ER proteostasis disturbances in Parkinson's disease: novel insights.

Front Aging Neurosci 2015 27;7:39. Epub 2015 Mar 27.

Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile Santiago, Chile ; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile Santiago, Chile ; Department of Immunology and Infectious Diseases, Harvard School of Public Health Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnagi.2015.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376001PMC
April 2015

Control of systemic proteostasis by the nervous system.

Trends Cell Biol 2015 Jan 28;25(1):1-10. Epub 2014 Aug 28.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Neurounion Biomedical Foundation, CENPAR, Santiago, Chile; Department of Immunology and Infectious diseases, Harvard School of Public Health, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2014.08.001DOI Listing
January 2015

Autophagy meets fused in sarcoma-positive stress granules.

Neurobiol Aging 2014 Dec 28;35(12):2832-2835. Epub 2014 Sep 28.

Neurounion Biomedical Foundation, CENPAR, Santiago, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324442PMC
December 2014

RESETing ER proteostasis: selective stress pathway hidden in the secretory route.

EMBO J 2014 Nov 4;33(21):2444-6. Epub 2014 Sep 4.

Biomedical Neuroscience Institute, Faculty of Medicine, Universidad de Chile, Santiago, Chile Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201489845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283403PMC
November 2014

Targeting autophagy in neurodegenerative diseases.

Trends Pharmacol Sci 2014 Nov 27;35(11):583-91. Epub 2014 Sep 27.

Neurounion Biomedical Foundation, CENPAR, Santiago, Chile; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2014.09.002DOI Listing
November 2014

Protein homeostasis: Modeling UPR adaptive responses.

Nat Chem Biol 2014 Nov;10(11):879-80

1] Biomedical Neuroscience Institute, ICBM Faculty of Medicine, University of Chile, Santiago, Chile. [2] Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nchembio.1653
Publisher Site
http://dx.doi.org/10.1038/nchembio.1653DOI Listing
November 2014

Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview.

Am J Physiol Cell Physiol 2014 Oct 20;307(7):C582-94. Epub 2014 Aug 20.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts; and Neurounion Biomedical Foundation, CENPAR, Santiago, Chile

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpcell.00258.2014DOI Listing
October 2014

Cell-nonautonomous control of the UPR: mastering energy homeostasis.

Cell Metab 2014 Sep;20(3):385-7

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Center for Molecular Studies of the Cell, University of Chile, Santiago, Chile; Neurounion Biomedical Foundation, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2014.07.009DOI Listing
September 2014

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.

Autophagy 2014 Jul 12;10(7):1256-71. Epub 2014 May 12.

Biomedical Neuroscience Institute; Faculty of Medicine; University of Chile; Santiago, Chile; Center for Molecular Studies of the Cell (CEMC); Program of Cellular and Molecular Biology; Institute of Biomedical Sciences; University of Chile; Neurounion Biomedical Foundation; Santiago, Chile; Department of Immunology and Infectious Diseases; Harvard School of Public Health; Boston, MA USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/auto.28784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203551PMC
July 2014

Common ground: stem cell approaches find shared pathways underlying ALS.

Cell Stem Cell 2014 Jun;14(6):697-9

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Independencia 1027, Chile; Neurounion Biomedical Foundation, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Independencia 1027, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19345909140018
Publisher Site
http://dx.doi.org/10.1016/j.stem.2014.05.001DOI Listing
June 2014

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.

Proc Natl Acad Sci U S A 2014 May 21;111(18):6804-9. Epub 2014 Apr 21.

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1321845111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020088PMC
May 2014

A novel ER stress-independent function of the UPR in angiogenesis.

Mol Cell 2014 May;54(4):542-4

Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile; Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA; Neurounion Biomedical Foundation, Santiago, Chile. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2014.05.013DOI Listing
May 2014

A new method to measure autophagy flux in the nervous system.

Autophagy 2014 Apr 17;10(4):710-4. Epub 2014 Mar 17.

Biomedical Neuroscience Institute; Faculty of Medicine; University of Chile; Santiago, Chile; Program of Cellular and Molecular Biology; Institute of Biomedical Sciences; University of Chile; Santiago, Chile; Center for Molecular Studies of the Cell; Faculty of Medicine; University of Chile; Santiago, Chile; Department of Immunology and Infectious Diseases; Harvard School of Public Health; Boston, MA USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/auto.28434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091163PMC
April 2014