Claudio Franceschi

Claudio Franceschi

UNVERIFIED PROFILE

Are you Claudio Franceschi?   Register this Author

Register author
Claudio Franceschi

Claudio Franceschi

Publications by authors named "Claudio Franceschi"

Are you Claudio Franceschi?   Register this Author

100Publications

1211Reads

44Profile Views

The carotid plaque as paradigmatic case of site-specific acceleration of aging process: The microRNAs and the inflammaging contribution.

Ageing Res Rev 2020 Aug 28;61:101090. Epub 2020 May 28.

DIMES-Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; Interdepartmental Center - Alma Mater Research Institute on Global Challenges and Climate Change - University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2020.101090DOI Listing
August 2020

Ecological Sensing Through Taste and Chemosensation Mediates Inflammation: A Biological Anthropological Approach.

Adv Nutr 2020 Jul 10. Epub 2020 Jul 10.

School of Anthropology and Museum Ethnography, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/advances/nmaa078DOI Listing
July 2020

Thyroid hormones and frailty in persons experiencing extreme longevity.

Exp Gerontol 2020 Jun 7;138:111000. Epub 2020 Jun 7.

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Cusano Milanino, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2020.111000DOI Listing
June 2020

Both objective and paradoxical insomnia elicit a stress response involving mitokine production.

Aging (Albany NY) 2020 May 17;12(11):10497-10505. Epub 2020 May 17.

IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.103274DOI Listing
May 2020

Lamin A involvement in ageing processes.

Ageing Res Rev 2020 May 21;62:101073. Epub 2020 May 21.

CNR Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", Unit of Bologna, Bologna, Italy; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2020.101073DOI Listing
May 2020

The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging).

Ageing Res Rev 2020 May 24;62:101091. Epub 2020 May 24.

Rostock University Medical Center, Institute for Clinical Chemistry and Laboratory Medicine, Rostock, Germany; Institute of Laboratory Medicine, Clinical Chemistry, and Pathobiochemistry, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2020.101091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245683PMC
May 2020

The Human Body as a Super Network: Digital Methods to Analyze the Propagation of Aging.

Front Aging Neurosci 2020 25;12:136. Epub 2020 May 25.

Department of Paediatrics and Paediatric Infectious Diseases, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnagi.2020.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261843PMC
May 2020

The Contextualized Genetics of Human Longevity: JACC Focus Seminar.

J Am Coll Cardiol 2020 Mar;75(8):968-979

Laboratory of Molecular Anthropology and Centre for Genome Biology, Department of Biological, Geological and Environmental Sciences, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2019.12.032DOI Listing
March 2020

Aging and Imaging Assessment of Body Composition: From Fat to Facts.

Front Endocrinol (Lausanne) 2019 14;10:861. Epub 2020 Jan 14.

Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fendo.2019.00861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970947PMC
January 2020

The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective.

Endocr Rev 2019 10;40(5):1250-1270

Istituto Auxologico Italiano, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/er.2018-00170DOI Listing
October 2019

Professor Dr. Mark Mattson's special contributions to ageing research and neuroscience.

Ageing Res Rev 2019 09 29;54:100905. Epub 2019 Apr 29.

University of Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2019.04.007DOI Listing
September 2019

Detrimental links between physical inactivity, metabolic risk and N-glycomic biomarkers of aging.

Exp Gerontol 2019 09 31;124:110626. Epub 2019 May 31.

School of Health Sciences, Örebro University, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2019.05.015DOI Listing
September 2019

Call for articles on neglected topics.

Ageing Res Rev 2019 Sep 15;54:100934. Epub 2019 Jul 15.

Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; C.I.G. Interdepartmental Centre "L. Galvani", Alma Mater Studiorum, University of Bologna, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2019.100934DOI Listing
September 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 08 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Age-Related DNA Methylation Changes: Potential Impact on Skeletal Muscle Aging in Humans.

Front Physiol 2019 2;10:996. Epub 2019 Aug 2.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2019.00996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688482PMC
August 2019

Accelerated bio-cognitive aging in Down syndrome: State of the art and possible deceleration strategies.

Aging Cell 2019 06 15;18(3):e12903. Epub 2019 Feb 15.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516152PMC
June 2019

Down Syndrome, Ageing and Epigenetics.

Subcell Biochem 2019;91:161-193

IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-981-13-3681-2_7DOI Listing
June 2019

The peculiar aging of human liver: A geroscience perspective within transplant context.

Ageing Res Rev 2019 05 14;51:24-34. Epub 2019 Feb 14.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; CIG-Interdepartmental Center "Galvani", University of Bologna, Bologna, Italy; CSR-Centro di Studio per la Ricerca dell'Invecchiamento, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2019.02.002DOI Listing
May 2019

Human Aging and Longevity Are Characterized by High Levels of Mitokines.

J Gerontol A Biol Sci Med Sci 2019 04;74(5):600-607

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Cusano Milanino.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/gly153DOI Listing
April 2019

The Impact of Caloric Restriction on the Epigenetic Signatures of Aging.

Int J Mol Sci 2019 Apr 24;20(8). Epub 2019 Apr 24.

IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20082022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515465PMC
April 2019

The Genetic Variability of in Different Human Populations and Its Implications for Longevity.

Genes (Basel) 2019 03 15;10(3). Epub 2019 Mar 15.

Laboratory of Molecular Anthropology & Centre for Genome Biology, Department of Biological, Geological and Environmental Sciences, University of Bologna, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/genes10030222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471373PMC
March 2019

Muscle-specific Perilipin2 down-regulation affects lipid metabolism and induces myofiber hypertrophy.

J Cachexia Sarcopenia Muscle 2019 02 4;10(1):95-110. Epub 2018 Oct 4.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jcsm.12355
Publisher Site
http://dx.doi.org/10.1002/jcsm.12355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438344PMC
February 2019

Cell-free DNA as a biomarker of aging.

Aging Cell 2019 02 20;18(1):e12890. Epub 2018 Dec 20.

Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/acel.12890
Publisher Site
http://dx.doi.org/10.1111/acel.12890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351822PMC
February 2019

The Dual Role of the Pervasive "Fattish" Tissue Remodeling With Age.

Front Endocrinol (Lausanne) 2019 26;10:114. Epub 2019 Feb 26.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fendo.2019.00114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400104PMC
February 2019

Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics.

Front Physiol 2018 24;9:1903. Epub 2019 Jan 24.

Université Clermont Auvergne, Institut National de la Recherche Agronomique, Unité de Nutrition Humaine, Centre Auvergne Rhône Alpes, Clermont-Ferrand, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2018.01903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353829PMC
January 2019

Inflammaging 2018: An update and a model.

Semin Immunol 2018 12 2;40:1-5. Epub 2018 Nov 2.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2018.10.008DOI Listing
December 2018

Vaccination in the elderly: The challenge of immune changes with aging.

Semin Immunol 2018 12;40:83-94

Laboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 16, 53100, Siena, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2018.10.010DOI Listing
December 2018

Inflammaging: a new immune-metabolic viewpoint for age-related diseases.

Nat Rev Endocrinol 2018 10;14(10):576-590

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41574-018-0059-4DOI Listing
October 2018

Hormetic approaches to the treatment of Parkinson's disease: Perspectives and possibilities.

J Neurosci Res 2018 10 11;96(10):1641-1662. Epub 2018 Aug 11.

Environmental Health Sciences Division, School of Public Health, University of Massachusetts, Amherst, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jnr.24244DOI Listing
October 2018

Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture Framework.

Circ Res 2018 09;123(7):745-772

IRCCS, Institute of Neurological Sciences of Bologna, Italy (C.F.).

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31256
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.118.312562DOI Listing
September 2018

Nutrition and Inflammation: Are Centenarians Similar to Individuals on Calorie-Restricted Diets?

Annu Rev Nutr 2018 08 31;38:329-356. Epub 2018 May 31.

Department of Experimental, Diagnostic, and Specialty Medicine (DIMES) and Interdepartmental Centre "L. Galvani" (CIG), Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy; email: ,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-nutr-082117-051637DOI Listing
August 2018

Sex Differences in Genetic Associations With Longevity.

JAMA Netw Open 2018 08 24;1(4):e181670. Epub 2018 Aug 24.

Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, North Carolina (Zeng, H. Chen); Center for Healthy Aging and Development Studies, National School of Development, Raissun Institute for Advanced Studies, Peking University, Beijing, China (Zeng, Bai); BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China (Nie);BGI-Shenzhen, Shenzhen, China (Nie, Xiaomin Liu, Ye, Z. Chen, Bolund, Hou, Xiao Liu, Xu, H. Yang); The First Affiliated Hospital, Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China (Min, E. Xie); Business School of Xiangtan University, Xiangtan, China (H. Chen); Division of Non-Communicable Disease Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China (Yin); National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China (Lv, Shi); Department of Sociology, Peking University, Beijing, China (Lu, Li); School of Life Sciences, Fudan University, Shanghai, China (Ni); Department of Biomedicine, Aarhus University, Aarhus, Denmark (Bolund); Duke Population Research Institute, Duke University, Durham, North Carolina (Land, Yashin, O'Rand); The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China (Sun, Z. Yang); School of Life Sciences, Peking University, Beijing, China (Tao, Gu); Boston University, Boston, Massachusetts (Gurinovich, Sebastiani, Perls); University of Bologna, Bologna, Italy (Franceschi); Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina (J. Xie); French National Institute on Health and Medical Research and Ecole Pratique des Hautes Etudes, University of Montpellier, Montpellier, France (Robine); Max Planck Institute for Biology of Ageing, Cologne, Germany (Deelen); Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (Slagboom); Molecular Physiology Institute, Medical Center, Duke University, Durham, North Carolina (Hauser); Department of Neurology, Medical Center, Duke University, Durham, North Carolina (Gottschalk, Lutz); University of Southern Denmark, Odense, Denmark (Tan, Christensen); Human Aging Research Institute and School of Life Science, Nanchang University, Jiangxi, China (Tian); James D. Watson Institute of Genome Sciences, Hangzhou, China (H. Yang); Max Planck Institute for Demographic Research, Rostock, Germany (Vaupel).

View Article

Download full-text PDF

Source
http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
Publisher Site
http://dx.doi.org/10.1001/jamanetworkopen.2018.1670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173523PMC
August 2018

Lifelong calorie restriction affects indicators of colonic health in aging C57Bl/6J mice.

J Nutr Biochem 2018 06 20;56:152-164. Epub 2018 Mar 20.

Division of Human Nutrition, Wageningen University & Research, 6708 WE, Wageningen, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jnutbio.2018.01.001DOI Listing
June 2018

Epigenetic DNA methylation changes in episodic and chronic migraine.

Neurol Sci 2018 Jun;39(Suppl 1):67-68

Department of Biomedical and Neuromotor Sciences, University of Bologna, 40123, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10072-018-3348-8DOI Listing
June 2018

Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing.

Ageing Res Rev 2018 Mar 5;42:1-13. Epub 2017 Dec 5.

CNR Institute of Molecular Genetics, Unit of Bologna, Via di Barbiano 1/10, I-40136, Bologna, Italy; Rizzoli Orthopedic Institute, Via di Barbiano 1/10, I-40136, Bologna, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2017.12.001DOI Listing
March 2018

The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates.

Front Med (Lausanne) 2018 12;5:61. Epub 2018 Mar 12.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmed.2018.00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890129PMC
March 2018

Biological age of transplanted livers.

Aging (Albany NY) 2018 Feb;10(2):156-157

Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://www.aging-us.com/article/101378/text
Publisher Site
http://dx.doi.org/10.18632/aging.101378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842843PMC
February 2018

Gut microbiota changes in the extreme decades of human life: a focus on centenarians.

Cell Mol Life Sci 2018 01 14;75(1):129-148. Epub 2017 Oct 14.

Institute of Neurological Sciences (IRCCS), Via Altura 3, 40139, Bologna, Italy.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00018-017-2674-y
Publisher Site
http://dx.doi.org/10.1007/s00018-017-2674-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752746PMC
January 2018

Age-Related Epigenetic Derangement upon Reprogramming and Differentiation of Cells from the Elderly.

Genes (Basel) 2018 Jan 16;9(1). Epub 2018 Jan 16.

Department of Specialty, Diagnostic and Experimental Medicine (DIMES), Via San Giacomo 12, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/genes9010039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793190PMC
January 2018

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

Front Immunol 2017 10;8:1960. Epub 2018 Jan 10.

Italian National Research Center on Aging, Department of Experimental Pathology, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2017.01960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767595PMC
January 2018

Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.

Oncotarget 2018 Jan 18;9(2):2279-2294. Epub 2017 Dec 18.

DIMES-Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.23406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639PMC
January 2018

Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition.

Ageing Res Rev 2017 Nov 9;40:95-119. Epub 2017 Sep 9.

Department of Molecular Medicine, University of Padova, 35121 Padova, Italy; IMDEA-Food, 28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2017.09.001DOI Listing
November 2017

Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity.

Front Immunol 2017 15;8:982. Epub 2017 Aug 15.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2017.00982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559470PMC
August 2017