Claudine Darnault

Claudine Darnault

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Claudine Darnault

Claudine Darnault

Publications by authors named "Claudine Darnault"

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Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu, and His Residues.

J Am Chem Soc 2019 Feb 1;141(6):2367-2375. Epub 2019 Feb 1.

Université Grenoble Alpes, CEA, CNRS , IBS , Metalloproteins Unit, F-38044 Grenoble , France.

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http://dx.doi.org/10.1021/jacs.8b10823DOI Listing
February 2019

Crystallographic Trapping of Reaction Intermediates in Quinolinic Acid Synthesis by NadA.

ACS Chem Biol 2018 05 19;13(5):1209-1217. Epub 2018 Apr 19.

Univ. Grenoble Alpes, CEA , CNRS, IBS, Metalloproteins Unit , F-38000 Grenoble , France.

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http://dx.doi.org/10.1021/acschembio.7b01104DOI Listing
May 2018

Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding.

Nat Commun 2017 04 20;8:15052. Epub 2017 Apr 20.

Metalloproteins Unit, Institut de Biologie Structurale, CEA, CNRS, Université Grenoble-Alpes, 71, avenue des Martyrs, CS 10090, 38044 Grenoble cedex 9, France.

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http://dx.doi.org/10.1038/ncomms15052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411485PMC
April 2017

Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product.

J Am Chem Soc 2016 09 30;138(36):11802-9. Epub 2016 Aug 30.

Metalloproteins Unit, Institut de Biologie Structurale, CEA, CNRS, Université Grenoble-Alpes , 71, Avenue des Martyrs, 38044 Grenoble Cedex 9, France.

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http://dx.doi.org/10.1021/jacs.6b05884DOI Listing
September 2016

The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium.

Sci Adv 2015 Dec 4;1(11):e1501086. Epub 2015 Dec 4.

Metalloproteins Unit, Institut de Biologie Structurale, CEA, CNRS, Université Grenoble Alpes, 71, Avenue des Martyrs CS10090, 38044 Grenoble, France.

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http://dx.doi.org/10.1126/sciadv.1501086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672761PMC
December 2015

The crystal structure of Fe₄S₄ quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad.

J Am Chem Soc 2014 Apr 26;136(14):5253-6. Epub 2014 Mar 26.

Metalloproteins Unit, Institut de Biologie Structurale, Commissariat à l'Energie Atomique-Centre National de la Recherche Scientifique, Université Grenoble-Alpes , 6 rue Jules Horowitz, 38000 Grenoble, France.

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http://dx.doi.org/10.1021/ja501431bDOI Listing
April 2014

Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b.

Structure 2013 Jan 20;21(1):184-190. Epub 2012 Dec 20.

Metalloproteins Unit, Institut de Biologie Structurale J.-P. Ebel CEA-CNRS-Université Joseph Fourier, UMR 5075, 41 rue Jules Horowitz, 38027 Grenoble, France. Electronic address:

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http://dx.doi.org/10.1016/j.str.2012.11.010DOI Listing
January 2013

X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli.

Proc Natl Acad Sci U S A 2012 Apr 19;109(14):5305-10. Epub 2012 Mar 19.

Metalloproteins Unit, Institut de Biologie Structurale J.-P. Ebel, Commissariat à l'Energie Atomique-Centre National de la Recherche Scientifique-l'Université Joseph Fourier, 41 Rue Jules Horowitz, 38027 Grenoble, France.

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http://dx.doi.org/10.1073/pnas.1119806109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325689PMC
April 2012

Low-temperature switching by photoinduced protonation in photochromic fluorescent proteins.

Photochem Photobiol Sci 2010 Feb 19;9(2):254-62. Epub 2010 Jan 19.

IBS, Institut de Biologie Structurale Jean-Pierre Ebel, CEA, CNRS, Université Joseph Fourier, 41 rue Jules Horowitz, F-38027, Grenoble, France.

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http://dx.doi.org/10.1039/b9pp00121bDOI Listing
February 2010

Structural basis of X-ray-induced transient photobleaching in a photoactivatable green fluorescent protein.

J Am Chem Soc 2009 Dec;131(50):18063-5

European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble Cedex, France.

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http://dx.doi.org/10.1021/ja907296vDOI Listing
December 2009

Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica.

Biochemistry 2009 Aug;48(33):7916-26

Laboratoire de Cristallographie et Cristallogenèse des Protéines, Institut de Biologie Structurale Jean-Pierre Ebel, CEA, CNRS, Université Joseph Fourier, 41 Rue Jules Horowitz, F-38027 Grenoble, France.

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http://pubs.acs.org/doi/abs/10.1021/bi9003952
Publisher Site
http://dx.doi.org/10.1021/bi9003952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795149PMC
August 2009

Simultaneous measurements of solvent dynamics and functional kinetics in a light-activated enzyme.

Biophys J 2009 Mar;96(5):1902-10

Institut de Biologie Structurale Jean-Pierre Ebel, Centre d'Etudes Atomiques, Centre National de la Recherche Scientifique, Université Joseph Fourier, Grenoble, France.

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http://dx.doi.org/10.1016/j.bpj.2008.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717306PMC
March 2009

Crystal structure of human iron regulatory protein 1 as cytosolic aconitase.

Structure 2006 Jan;14(1):129-39

Laboratoire de Cristallographie et de Cristallogenèse des Protéines, Institut de Biologie Structurale JP Ebel, CEA/CNRS/Université Joseph Fourier, 38027 Grenoble Cedex 1, France.

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http://dx.doi.org/10.1016/j.str.2005.09.009DOI Listing
January 2006

The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties.

J Biol Chem 2003 Nov 5;278(47):46974-82. Epub 2003 Sep 5.

Laboratoire de Cristallographie et Cristallogéncse des Protéines, Institut de Biologie Structurale Jean-Pierre Ebel, Commissariat à l'Energie Atomique (CEA)-CNRS-Université Joseph Fourier, 41 rue Jules Horowitz, 38027 Grenoble Cedex 1, France.

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http://dx.doi.org/10.1074/jbc.M307764200DOI Listing
November 2003

Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase.

Nat Struct Biol 2003 Apr;10(4):271-9

Laboratoire de Cristallographie et Cristallogenèse des Protéines, Institut de Biologie Structurale 'Jean-Pierre Ebel', CEA, UJF, CNRS, 41, rue Jules Horowitz, 38027, Grenoble Cedex 1, France.

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http://dx.doi.org/10.1038/nsb912DOI Listing
April 2003

CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

Nat Immunol 2003 Mar 3;4(3):241-7. Epub 2003 Feb 3.

Laboratoire de Cristallographie et Cristallogenèse des Protéines, Institut de Biologie Structurale J.-P. Ebel, CEA-CNRS-UJF, 41 rue Jules Horowitz, F-38027 Grenoble Cedex 1, France.

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http://dx.doi.org/10.1038/ni891DOI Listing
March 2003

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.

Immunity 2002 Mar;16(3):345-54

Laboratoire de Cristallographie et Cristallogénèse des Protéines, Institut de Biologie Structurale J.-P. Ebel, CEA-CNRS-UJF, 41 rue Jules Horowitz, F-38027 Grenoble Cedex 1, France.

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http://dx.doi.org/10.1016/s1074-7613(02)00288-1DOI Listing
March 2002