Claudia Trenkwalder

Claudia Trenkwalder

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Claudia Trenkwalder

Publications by authors named "Claudia Trenkwalder"

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Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson's Disease.

Cell Rep 2019 Nov;29(7):1767-1777.e8

School of Medicine, National University of Galway, Galway, Ireland; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg; Division of Microbiology, National University of Galway, Galway, Ireland; APC Microbiome Ireland, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.035DOI Listing
November 2019

Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease.

Neurobiol Dis 2019 Nov 13:104677. Epub 2019 Nov 13.

Department of Neurology, University Medical Center Goettingen, Germany; DZNE, German Center for Neurodegenerative Diseases Goettingen, Germany; Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Goettingen, Germany; Center for Biostructural Imaging of Neurodegeneration (BIN), University Medical Center Goettingen, Germany; Department of Neurology, Rechts der Isar Hospital of the Technical University Munich, 80333 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104677DOI Listing
November 2019

SEAweb: the small RNA Expression Atlas web application.

Nucleic Acids Res 2019 Oct 10. Epub 2019 Oct 10.

Institute of Medical Systems Biology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.

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http://dx.doi.org/10.1093/nar/gkz869DOI Listing
October 2019

White matter hyperintensities are not associated with cognitive decline in early Parkinson's disease - The DeNoPa cohort.

Parkinsonism Relat Disord 2019 Oct 19;69:61-67. Epub 2019 Oct 19.

Institute of Epidemiology and Social Medicine, University of Muenster, Albert-Schweitzer-Campus 1, D-48149, Muenster, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2019.10.016DOI Listing
October 2019

Sleep-Related Disorders in Neurology and Psychiatry.

Dtsch Arztebl Int 2019 Oct;116(41):681-688

Department of Neurology, Medical Center of the Ludwig-Maximilians-University of Munich (LMU), Germany; Center of Mental Health, Klinikum Ingolstadt, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Medical Faculty, University of Freiburg, Germany; Center of Parkinsonism and Movement Disorders, Paracelsus-Elena Hospital, Kassel, Germany and Department of Neurosurgery, University Medical Center Göttingen, Germany; Specialized Clinic for Therapies in Neurology, Medical Park Reithofpark, Bad Feilnbach, Germany.

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http://dx.doi.org/10.3238/arztebl.2019.0681DOI Listing
October 2019

Quality of life predicts outcome of deep brain stimulation in early Parkinson disease.

Neurology 2019 03 8;92(10):e1109-e1120. Epub 2019 Feb 8.

From the Département de Neurologie (W.M.M.S., A.H., T.D.H., F.P., Y.A., M.V.), Hôpital Pitié-Salpêtrière, Centre d'Investigation Clinique 1422, Institut du Cerveau et de la Moelle Epinière, Institut National de Santé et en Recherche Médicale, Assistance Publique Hôpitaux de Paris, France; Institute of Neurology (W.M.M.S.), Konolfingen; Department of Neurology (W.M.M.S.), University Hospital Bern and University of Bern, Switzerland; Medtronic (L.T.), Minneapolis, MN; Institute of Clinical Neuroscience & Medical Psychology and Department of Neurology (A.D., L.W.), Medical Faculty, Heinrich-Heine-University Düsseldorf, Germany; Movement Disorder Unit, Neurology (P.K.), CHU Grenoble Alpes; Grenoble Institut des Neurosciences (P.K., V.F., A. Kistner), University Grenoble Alpes; Inserm U1216 (P.K., V.F., A. Kistner), Grenoble, France; Department of Clinical Neurosciences (Neurology) (P.K.), Faculty of Medicine, University of Geneva, Switzerland; Coordinating Center for clinical trials of the Philipps University of Marburg (J.R., C.S.-B.); Neurochirurgische Klinik im Neurozentrum (A.F., L.P., S.P., J. Volkmann, K.K., G.D.),Christian-Albrechts-Universität Kiel; Neurologische Klinik und Poliklinik (J. Volkmann), Universitätsklinikum Würzburg; Department of Neurology (H.S.D., M.T.B., G.R.F., L.T.), University Hospital Cologne; Research Centre Jülich (G.R.F.); Klinik für Neurologie (T.D.H., A. Kühn, A. Kupsch) and Klinik für Neurochirurgie (G.-H.S.), Campus Virchow, Charité-Universitätsmedizin Berlin; Praxis Kupsch (A. Kupsch), Berlin, Germany; Service de Neurochirurgie (E.S.) and Service de Neurologie (V.F.), Hôpital Michallon, Centre Hospitalo-Universitaire, Grenoble; Departments of Neurosurgery (P.P.C.), Neurology (F.O.-M., C.B.-C.), and Clinical Pharmacology (C.B.-C.), University Hospital of Toulouse; ToNIC (F.O.-M., C.B.-C.), Toulouse Neuroimaging Center, University of Toulouse, Inserm, UPS, France; Department of Neurosurgery (J. Vesper), Universitätsklinikum Düsseldorf, Germany; Departments of Neurosurgery (S.D.) and Neurology (D.M.), Rouen University Hospital and University of Rouen; INSERM U1239 (D.M.), Laboratory of Neuronal and Neuroendocrine Differentiation and Communication, Mont-Saint-Aignan; Service de Neurologie (P. Damier, P. Derkinderen), CHU Nantes, Hôpital Laënnec, France; Paracelsus-Elena-Klinik Kassel (F.S.-D., C.T.); Department of Neurosurgery (C.T.), University Medical Center Göttingen; Division of Functional and Restorative Neurosurgery and Centre for Integrative Neuroscience (A.G.), Tübingen; Abteilung für Neurologie (T.W.), Reha-Zentrum Bad Gögging, Passauer Wolf; Department for Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research (D.W.), University of Tübingen; Division of Stereotactic and Functional Neurosurgery (M.O.P.), University Medical Center Freiburg, Germany; Departments of Functional and Stereotactic Neurosurgery and Radiosurgery (J.-.M.R.) and Neurology (T.W.), Timone University Hospital, INSERM, Marseille; Institut des Sciences Cognitives Marc Jeannerod (S.T.), CNRS, UMR 5229, Université de Lyon; Centre Expert Parkinson (S.T.), Service de Neurologie C, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron; Department of Neurosurgery (P.M.), University Hospital of Neurology and Neurosurgery, Hospices Civils de Lyon, Université de Lyon; Department of Neurology (J.-L.H.), INSERM-1402, Centre Hospitalier Universitaire de Poitiers, University of Poitiers, France; and Universitätsklinikum Giessen und Marburg (L.T.), Marburg Campus, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442017PMC
March 2019

Increased dose of carbidopa with levodopa and entacapone improves "off" time in a randomized trial.

Neurology 2019 Mar 1;92(13):e1487-e1496. Epub 2019 Mar 1.

From the Clinic of Neurosurgery (C.T.), University Medical Center of Goettingen, Germany; Orion Pharma (M.K., M.V., J.E.), Espoo, Finland; and Klink für Neurologie (T.M.), Alexianer St. Joseph Berlin-Weissensee GmbH, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453771PMC
March 2019

Pharmacological treatments of augmentation in restless legs syndrome patients.

Adv Pharmacol 2019 20;84:255-265. Epub 2019 Mar 20.

Department of Clinical Neurophysiology, University Medical Center Göttingen, Georg August University, Göttingen, Germany.

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http://dx.doi.org/10.1016/bs.apha.2019.02.002DOI Listing
March 2019

I contributes to increased motoneuron excitability in restless legs syndrome.

J Physiol 2019 Jan 24;597(2):599-609. Epub 2018 Nov 24.

Department of Clinical Neurophysiology, Medical School Göttingen, University of Göttingen, Göttingen, Germany.

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http://doi.wiley.com/10.1113/JP275341
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http://dx.doi.org/10.1113/JP275341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332783PMC
January 2019

Validation of a new data-driven automated algorithm for muscular activity detection in REM sleep behavior disorder.

J Neurosci Methods 2019 01 20;312:53-64. Epub 2018 Nov 20.

Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1016/j.jneumeth.2018.11.016DOI Listing
January 2019

Reply to: Safety of dopamine agonists for treating restless legs syndrome.

Mov Disord 2019 01;34(1):150-151

Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1002/mds.27571DOI Listing
January 2019

Relationship of Nocturnal Sleep Dysfunction and Pain Subtypes in Parkinson's Disease.

Mov Disord Clin Pract 2019 Jan 8;6(1):57-64. Epub 2018 Nov 8.

Institute of Psychiatry, Psychology, & Neuroscience at King's College and King's College Hospital NHS Foundation Trust London United Kingdom.

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http://dx.doi.org/10.1002/mdc3.12694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335509PMC
January 2019

Comorbidities, treatment, and pathophysiology in restless legs syndrome.

Lancet Neurol 2018 11 21;17(11):994-1005. Epub 2018 Sep 21.

Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany; Institute of Human Genetics, Technical University, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1016/S1474-4422(18)30311-9DOI Listing
November 2018

Polysomnographic findings in restless legs syndrome (RLS) patients with severe augmentation.

Sleep Med 2018 08 5;48:79-85. Epub 2018 May 5.

Paracelsus Elena Hospital, Kassel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2018.04.010DOI Listing
August 2018

Placebo and nocebo responses in other movement disorders besides Parkinson's disease: How much do we know?

Mov Disord 2018 08;33(8):1228-1235

Parkinson's Disease and Movement Disorders Center, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1002/mds.113DOI Listing
August 2018

LRRK2 protective haplotype and full sequencing study in REM sleep behavior disorder.

Parkinsonism Relat Disord 2018 07 21;52:98-101. Epub 2018 Mar 21.

Montreal Neurological Institute, McGill University, Montréal, QC, H3A 0G4, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, QC, H3A 0G4, Canada, Canada; Department of Human Genetics, McGill University, H3A 0G4, Montréal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.03.019DOI Listing
July 2018

Sleep-related motor and behavioral disorders: Recent advances and new entities.

Mov Disord 2018 07 14;33(7):1042-1055. Epub 2018 May 14.

Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Toronto, Canada.

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http://dx.doi.org/10.1002/mds.27375DOI Listing
July 2018

Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017).

Mov Disord 2018 07 14;33(7):1077-1091. Epub 2018 May 14.

CHDI Foundation, Princeton, Princeton, NJ, USA, and the Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal.

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http://dx.doi.org/10.1002/mds.27260DOI Listing
July 2018

Getting a good night sleep? The importance of recognizing and treating nocturnal hypokinesia in Parkinson's disease.

Parkinsonism Relat Disord 2018 05 5;50:10-18. Epub 2018 Jan 5.

Department of Neurosurgery, University Medical Center Gottingen, Paracelsus Elena Hospital, Kassel, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2018.01.008DOI Listing
May 2018

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder.

Mov Disord 2018 01 26;33(1):88-98. Epub 2017 Aug 26.

Eco-Systems Biology Research Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.1002/mds.27105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811909PMC
January 2018

Drug Safety Analysis in a Real-Life Cohort of Parkinson's Disease Patients with Polypharmacy.

CNS Drugs 2017 12;31(12):1093-1102

Department of Translational Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, 81677, Munich, Germany.

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http://dx.doi.org/10.1007/s40263-017-0478-0DOI Listing
December 2017

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Lancet Neurol 2017 11;16(11):898-907

Institute of Neurogenomics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany; Neurologische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30327-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755468PMC
November 2017

What would Dr. James Parkinson think today? The 21st Annual Congress of the International Parkinson's disease and movement disorders society.

Mov Disord 2017 07;32(7):951-954

Department of Neurosurgery, University Medical Center, Goettingen, and Paracelsus-Elena Hospital, Kassel, Germany.

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http://dx.doi.org/10.1002/mds.27108DOI Listing
July 2017

Placebo and nocebo responses in restless legs syndrome: A systematic review and meta-analysis.

Neurology 2017 Jun 10;88(23):2216-2224. Epub 2017 May 10.

From the Laboratory of Clinical Pharmacology and Therapeutics (M.A.S., G.S.D., R.C., F.B.R., R.M.F., D.A., J.C., J.J.F.), Portuguese Collaborating Center of the IberoAmerican Cochrane Network, Cochrane Portugal (G.S.D., R.M.F., J.C.), and Center for Evidence-Based Medicine (J.C.), Faculty of Medicine, University of Lisbon; Clinical Pharmacology Unit (M.A.S., G.S.D., R.C., F.B.R., R.M.F., D.A., J.C., J.J.F.), Instituto de Medicina Molecular, Lisbon, Portugal; Huntington's Disease Centre (F.B.R.), Institute of Neurology, University College London, UK; Parkinson's Disease and Movement Disorders Center (T.M.), Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Canada; Paracelsus-Elena Klinik (C.T.), Center of Parkinsonism and Movement Disorders, Kassel; and the Department of Neurosurgery (C.T.), University Medical Center, Göttingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004004DOI Listing
June 2017

Neurodegeneration in REM sleep behavior disorder: Stratification keeps improving.

Neurology 2017 04 22;88(16):1486-1487. Epub 2017 Mar 22.

From the Department of Neurology (R.B.P), McGill University, Montreal General Hospital, Quebec, Canada; and Elena-Klinik (C.T.), Kassel and University Medical Center, Goettingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000003850DOI Listing
April 2017

Pain, opioids, and sleep: implications for restless legs syndrome treatment.

Sleep Med 2017 03 5;31:78-85. Epub 2016 Nov 5.

Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.sleep.2016.09.017DOI Listing
March 2017

Management of augmentation of restless legs syndrome with rotigotine: a 1-year observational study.

Sleep Med 2017 02 11;30:257-265. Epub 2015 Nov 11.

Somni Bene Institut fur Medizinische Forschung und Schlafmedizin, Schwerin, Germany and Rostock University, Medical Center, Rostock, Germany.

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http://dx.doi.org/10.1016/j.sleep.2015.10.006DOI Listing
February 2017

Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid.

JAMA Neurol 2017 Feb;74(2):163-172

Mitchell Center for Alzheimer's Disease and Related Brain Disorders, The University of Texas School of Medicine at Houston.

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http://dx.doi.org/10.1001/jamaneurol.2016.4547DOI Listing
February 2017

Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Neurology 2016 Dec 16;87(24):2585-2593. Epub 2016 Nov 16.

From Harvard Medical School and Massachusetts General Hospital (J.W.W.), Boston; Department of Neurology (M.J.A.), University of Florida College of Medicine, Gainesville; Department of Neurology (R.P.A.), Johns Hopkins University, Baltimore, MD; King's College and King's College Hospital (K.R.C.), London; Methodist Neurological Institute (W.O.), Houston, TX; Department of Neurology (C.T.), University Medical Center, Göttingen, Germany; Northwestern University Feinberg School of Medicine (P.C.Z.), Chicago, IL; University of Kansas Medical Center (G.S.G.), Kansas City; CAMC Neurology Section (D.G.), Charleston, WV; and Department of Neurology (T.Z.), University of South Florida, James A Haley Veterans Administration Hospital, Tampa.

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http://dx.doi.org/10.1212/WNL.0000000000003388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206998PMC
December 2016

Asphyxia due to laryngeal spasm as a severe complication of awake deep brain stimulation for Parkinson's disease: a case report.

BMC Neurol 2016 Nov 8;16(1):216. Epub 2016 Nov 8.

Department of Neurosurgery, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1186/s12883-016-0736-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100222PMC
November 2016

Validation of the Kohnen Restless Legs Syndrome-Quality of Life instrument.

Sleep Med 2016 08 3;24:10-17. Epub 2016 Aug 3.

Department of Neurology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2016.04.019DOI Listing
August 2016

Clinically relevant cut-off values for the Parkinson's Disease Sleep Scale-2 (PDSS-2): a validation study.

Sleep Med 2016 08 24;24:87-92. Epub 2016 Aug 24.

Paracelsus Elena Hospital, Kassel, Germany; Department Neurosurgery, University of Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1016/j.sleep.2016.06.026DOI Listing
August 2016

Monitoring of 30 marker candidates in early Parkinson disease as progression markers.

Neurology 2016 07 6;87(2):168-77. Epub 2016 May 6.

From Paracelsus-Elena-Klinik (B.M., F.S.-D., T.W., J.E., M.S., E.L., E.T., C.T.), Kassel; Departments of Neurosurgery (B.M., C.T.) and Medical Statistics (T.F.) and Institute of Neuropathology (B.M.), University Medical Centre Göttingen; Psychologische Hochschule Berlin (J.Z.); Department of Neurology/Epileptology and Hertie Institute of Clinical Brain Research (N.K.F.), University of Tübingen, Germany; Clinical Neurochemistry Laboratory (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology (H.Z.), Queen Square, London, UK; and BioLegend (P.T.), Dedham, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940068PMC
July 2016

Rotigotine's effect on PLM-associated blood pressure elevations in restless legs syndrome: An RCT.

Neurology 2016 May 13;86(19):1785-93. Epub 2016 Apr 13.

From the Munich University Clinic and DZHK (German Centre for Cardiovascular Research) (A.B.); Philipps Universität Marburg (W.C., K.K., W.O.); Somni Bene Institut für Medizinische Forschung und Schlafmedizin (H.B.), Schwerin; Medical Center (H.B.), Rostock University, Germany; Emory University (D.R.), Atlanta, GA; Virginia Commonwealth University (D.S.), Richmond; Massachusetts General Hospital (J.W.W.), Boston; UCB Pharma (L.B., F.G., L.J., E.S.), Monheim am Rhein, Germany; UCB Pharma (K.M.), Smyrna, GA; UCB Pharma (J.W.), Raleigh, NC; Evidence Scientific Solutions (H.C.C.), Horsham, UK; Vanderbilt University School of Medicine (A.S.W.), Nashville, TN; Hertie Foundation (W.O.), Frankfurt am Main; and Department of Neurosurgery (C.T.), University Medical Center, Göttingen and Paracelsus-Elena-Klinik, Kassel, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000002649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862252PMC
May 2016

Restless legs syndrome associated with major diseases: A systematic review and new concept.

Neurology 2016 Apr 4;86(14):1336-1343. Epub 2016 Mar 4.

From Center of Parkinsonism and Movement Disorders (C.T.), Paracelsus-Elena Hospital, Kassel; Departments of Neurosurgery (C.T.) and Clinical Neurophysiology (W.P.), University Medical Center, Göttingen, Germany; Department of Neurology (R.A.), The Johns Hopkins Bayview Medical Center, Baltimore, MD; Department of Neurology (B.H.), Medical University of Innsbruck, Austria; Institute for Neurogenomic (J.W.), Helmholtz Zentrum München, Neuherberg; Neurologische Klinik und Poliklinik (J.W.), Klinikum rechts der Isar, Technische Universität München, Munich; and Munich Cluster for Systems Neurology (SyNergy) (J.W.), Munich, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000002542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826337PMC
April 2016

Rating of daytime and nighttime symptoms in RLS: validation of the RLS-6 scale of restless legs syndrome/Willis-Ekbom disease.

Sleep Med 2016 04 26;20:116-22. Epub 2015 Nov 26.

Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2015.10.014DOI Listing
April 2016

Significant association between systolic and diastolic blood pressure elevations and periodic limb movements in patients with idiopathic restless legs syndrome.

Sleep Med 2016 Jan 23;17:109-20. Epub 2015 Feb 23.

University Medical Center, Department of Neurosurgery, Göttingen and Paracelsus-Elena-Klinik, Kassel, Germany.

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http://dx.doi.org/10.1016/j.sleep.2014.12.019DOI Listing
January 2016

Distinctive distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.

Mov Disord 2015 Oct 14;30(12):1688-92. Epub 2015 Jul 14.

Department of Neurology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/mds.26293DOI Listing
October 2015

Serum Ferritin Levels in Parkinson's Disease Patients with and without Restless Legs Syndrome.

Mov Disord Clin Pract 2015 Sep 4;2(3):249-252. Epub 2015 Jun 4.

Paracelsus Elena Klinik Kassel Germany.

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http://dx.doi.org/10.1002/mdc3.12165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178747PMC
September 2015

Restless legs syndrome-current therapies and management of augmentation.

Nat Rev Neurol 2015 Aug 28;11(8):434-45. Epub 2015 Jul 28.

Department of Clinical Neurophysiology, University Medical Centre Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1038/nrneurol.2015.122DOI Listing
August 2015

REM Sleep Behavioral Events and Dreaming.

J Clin Sleep Med 2015 Apr 15;11(5):537-41. Epub 2015 Apr 15.

Paracelsus Elena Klinik Kassel, Germany.

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http://dx.doi.org/10.5664/jcsm.4698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410927PMC
April 2015

REM sleep-associated motor behaviors in Parkinson's disease patients with heterozygous Parkin mutations.

Mov Disord 2015 Apr 15;30(4):597-8. Epub 2015 Mar 15.

Paracelsus-Elena Klinik, Center for Parkinsonism and Movement Disorders, Kassel, Germany; Department of Neurology, Philipps-University Marburg, Germany.

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http://dx.doi.org/10.1002/mds.26193DOI Listing
April 2015

Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.

PLoS One 2014 29;9(5):e98092. Epub 2014 May 29.

Neurologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Institut für Humangenetik, Helmholtz Zentrum München, Munich, Germany; Institut für Humangenetik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098092PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038519PMC
January 2015

Diagnostic value of the REM sleep behavior disorder screening questionnaire in Parkinson's disease.

Sleep Med 2015 Jan 13;16(1):186-9. Epub 2014 Nov 13.

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2014.08.014DOI Listing
January 2015

Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders.

PLoS One 2013 30;8(12):e82879. Epub 2013 Dec 30.

Neurologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany ; Institut für Humangenetik, Helmholtz Zentrum München, Munich, Germany ; Institut für Humangenetik, Technische Universität München, Munich, Germany ; Munich Cluster for Systems Neurology, SyNergy, Munich, Germany ; Department of Neurology and Neurological Sciences and Center for Sleep Sciences and Medicine, Stanford University School of Medicine, Palo Alto, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082879PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875432PMC
September 2014

Cutaneous neuropathy in Parkinson's disease: a window into brain pathology.

Acta Neuropathol 2014 Jul 1;128(1):99-109. Epub 2014 May 1.

Department of Neurology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany,

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http://dx.doi.org/10.1007/s00401-014-1284-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059960PMC
July 2014

Hypothalamo-pituitary-adrenal axis activity evolves differentially in untreated versus treated multiple sclerosis.

Psychoneuroendocrinology 2014 Jul 2;45:87-95. Epub 2014 Apr 2.

Max Planck Institute of Psychiatry, Section of Neurology, Kraepelinstrasse 10, 80804 München, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03064530140010
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http://dx.doi.org/10.1016/j.psyneuen.2014.03.012DOI Listing
July 2014

Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome.

Am J Hum Genet 2014 Jul;95(1):85-95

Neurologische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany; Institut für Humangenetik, Helmholtz Zentrum München, 85764 Munich, Germany; Institut für Humangenetik, Technische Universität München, 81675 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Department of Neurology and Neurosciences, Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, CA 94304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085638PMC
July 2014

Multimorbidity and the risk of restless legs syndrome in 2 prospective cohort studies.

Neurology 2014 Jun 7;82(22):2026-33. Epub 2014 May 7.

From the Institute of Epidemiology and Social Medicine (A.S., K.B.), University of Münster, Germany; Institute of Behavioural Sciences (A.S.), Semmelweis University, Budapest, Hungary; Institute for Community Medicine (H.V., W.H.), University Medicine Greifswald; German Centre for Cardiovascular Research (H.V.), Partner site Greifswald; German Centre for Neurodegenerative Diseases (DZNE) (W.H.); Paracelsus-Elena Hospital (C.T.), Kassel; and Department of Neurosurgery (C.T.), University Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000000470DOI Listing
June 2014

Embryonic stem cell-derived neural progenitors as non-tumorigenic source for dopaminergic neurons.

World J Stem Cells 2014 Apr;6(2):248-55

Mei-Chih Liao, Mihaela Diaconu, Ahmed Mansouri, Department of Molecular Cell Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.

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http://dx.doi.org/10.4252/wjsc.v6.i2.248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999782PMC
April 2014

Rapid eye movement sleep behavioral events: a new marker for neurodegeneration in early Parkinson disease?

Sleep 2014 Mar 1;37(3):431-8. Epub 2014 Mar 1.

Paracelsus-Elena-Klinik, Kassel, Germany ; Department of Neurosurgery, Georg-August University Goettingen, Germany.

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https://academic.oup.com/sleep/article/37/3/431/2595936
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http://dx.doi.org/10.5665/sleep.3468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920307PMC
March 2014

REM sleep behavior disorder in Parkinson's disease.

J Neural Transm (Vienna) 2014 Mar 22. Epub 2014 Mar 22.

Paracelsus Elena Klinik, Klinik Str. 16, 34128, Kassel, Germany,

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http://dx.doi.org/10.1007/s00702-014-1192-4DOI Listing
March 2014

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort.

Neurology 2013 Oct 30;81(14):1226-34. Epub 2013 Aug 30.

From the Center of Parkinsonism and Movement Disorders (B.M., E.T., F.S.-D., T.W., J.E., M.S., E.L., C.T.), Paracelsus-Elena-Klinik, Kassel; Department of Neurosurgery (B.M., N.K.F., C.T.), University Medical Centre, Goettingen; Department of Psychology (E.T.), University Kassel; Section of Clinical and Molecular Neurogenetics at the Department of Neurology (K.R.K., K.L., C.K.), University of Luebeck; Departments of Neuropathology (B.M.) and Medical Statistics (T.F.), University Medical Centre, Goettingen, Germany; Program in Neuroscience (M.G.S.), Ottawa Hospital Research Institute; Division of Neurology, The Ottawa Hospital, University of Ottawa, Canada; and ReSearch Pharmaceutical Services (R.K.), Nuremberg, Germany.

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http://dx.doi.org/10.1212/WNL.0b013e3182a6cbd5DOI Listing
October 2013

Impairment of brainstem implicit learning paradigms differentiates multiple system atrophy (MSA) from idiopathic Parkinson syndrome.

BMJ Open 2013 Sep 13;3(9):e003098. Epub 2013 Sep 13.

Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1136/bmjopen-2013-003098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773641PMC
September 2013

No Difference in Sleep and RBD between Different Types of Patients with Multiple System Atrophy: A Pilot Video-Polysomnographical Study.

Sleep Disord 2013 28;2013:258390. Epub 2013 Mar 28.

Paracelsus Elena Klinik, Klinik Straße 16, 34128 Kassel, Germany ; Department of Neurosciences, University of Medicine and Pharmacy, Victor Babes Straße 43, 400012 Cluj-Napoca, Romania.

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http://dx.doi.org/10.1155/2013/258390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654360PMC
June 2013