Claudia Schulte

Claudia Schulte

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Claudia Schulte

Publications by authors named "Claudia Schulte"

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Selenium speciation analysis in the cerebrospinal fluid of patients with Parkinson's disease.

J Trace Elem Med Biol 2020 Jan 24;57:126412. Epub 2019 Sep 24.

Department of Neurology, University Medical Center, Göttingen, Germany; DZNE, German Center for Neurodegenerative Diseases, Göttingen, Germany; Center for Biostructural Imaging of Neurodegeneration (BIN), University of Göttingen Medical Center, Göttingen, Germany; Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neurology, München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jtemb.2019.126412DOI Listing
January 2020

Machine Learning to Detect Alzheimer's Disease from Circulating Non-coding RNAs.

Genomics Proteomics Bioinformatics 2019 Dec 3. Epub 2019 Dec 3.

Chair for Clinical Bioinformatics, Saarland University, 66123 Saarbrücken, Germany; Center for Bioinformatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2019.09.004DOI Listing
December 2019

Alterations in Blood Monocyte Functions in Parkinson's Disease.

Mov Disord 2019 Nov 26;34(11):1711-1721. Epub 2019 Aug 26.

DANDRITE & Department of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1002/mds.27815DOI Listing
November 2019

Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease.

Neurobiol Dis 2019 Nov 13;134:104677. Epub 2019 Nov 13.

Department of Neurology, University Medical Center Goettingen, Germany; DZNE, German Center for Neurodegenerative Diseases Goettingen, Germany; Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Goettingen, Germany; Center for Biostructural Imaging of Neurodegeneration (BIN), University Medical Center Goettingen, Germany; Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104677DOI Listing
November 2019

A combined miRNA-piRNA signature to detect Alzheimer's disease.

Transl Psychiatry 2019 Oct 7;9(1):250. Epub 2019 Oct 7.

Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE) Goettingen, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1038/s41398-019-0579-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779890PMC
October 2019

Parkinson's Disease: Glucocerebrosidase 1 Mutation Severity Is Associated with CSF Alpha-Synuclein Profiles.

Mov Disord 2019 Oct 30. Epub 2019 Oct 30.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.27884DOI Listing
October 2019

p.V363I mutation: A rare cause of corticobasal degeneration.

Neurol Genet 2019 Aug 25;5(4):e347. Epub 2019 Jun 25.

Neurodegenerative Disease Research Unit (S.A., M.S.S., S.W.S.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Movement Disorders and Memory Unit (M.D.F., P.P.), Department of Neurology, University Hospital Mutua de Terrassa, and Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Barcelona, Spain; Laboratory of Neurogenetics (J.D.), National Institutes on Aging, National Institutes of Health, Bethesda, MD; Neurology Service (L.I.), Hospital Universitari Germans Trias, Pujol, Badalona, Spain; Department of Neurology (A.B., A.P., S.W.S.), Johns Hopkins University Medical Center, Baltimore, MD; Newcastle Institute for Ageing (C.M.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Neurodegenerative Diseases (C.S., T.G.), Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tuebingen, and German Center for Neurodegenerative Diseases, Germany; Department of Molecular and Clinical Neuroscience (E.J., H.R.M.), Institute of Neurology, University College London, United Kingdom; Department of Pathology (Neuropathology) (O.P., J.T.), Johns Hopkins University Medical Center, Baltimore, MD; Department of Clinical Neurosciences (H.R.M.), Royal Free Campus UCL, Institute of Neurology, London, United Kingdom; Neurological Tissue Bank (E.G.), University of Barcelona-Hospital Clinic, IDIBAPS, Barcelona, Spain; and Institute of Neurology (E.G.), Medical University of Vienna, Austria.

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http://dx.doi.org/10.1212/NXG.0000000000000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659135PMC
August 2019

Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.

Mov Disord 2019 07 12;34(7):1069-1073. Epub 2019 Jun 12.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.27731DOI Listing
July 2019

Cerebrospinal fluid biogenic amines depletion and brain atrophy in adult patients with phenylketonuria.

J Inherit Metab Dis 2019 May 1;42(3):398-406. Epub 2019 Feb 1.

Department of Pediatrics, Division for Neuropediatrics and Metabolic Medicine, University of Heidelberg, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/jimd.12049
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http://dx.doi.org/10.1002/jimd.12049DOI Listing
May 2019

Parkinson's disease: evolution of cognitive impairment and CSF Aβ profiles in a prospective longitudinal study.

J Neurol Neurosurg Psychiatry 2019 02 25;90(2):165-170. Epub 2018 Sep 25.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1136/jnnp-2018-318956DOI Listing
February 2019

Biallelic Parkin (PARK2) mutations can cause a bvFTD phenotype without clinically relevant parkinsonism.

Parkinsonism Relat Disord 2018 10 6;55:145-147. Epub 2018 Jun 6.

Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.06.006DOI Listing
October 2018

Cholinergic Pathway SNPs and Postural Control in 477 Older Adults.

Front Aging Neurosci 2018 4;10:260. Epub 2018 Sep 4.

Department of Neurodegenerative Diseases, Center of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00260
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http://dx.doi.org/10.3389/fnagi.2018.00260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131592PMC
September 2018

Polygenic load: Earlier disease onset but similar longitudinal progression in Parkinson's disease.

Mov Disord 2018 08 22;33(8):1349-1353. Epub 2018 Aug 22.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.27427DOI Listing
August 2018

Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease.

Front Aging Neurosci 2018 5;10:51. Epub 2018 Mar 5.

Department of Neurodegeneration, German Center for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3389/fnagi.2018.00051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844983PMC
March 2018

SNPs in Aβ clearance proteins: Lower CSF Aβ levels and earlier onset of dementia in PD.

Neurology 2017 Dec 8;89(23):2335-2340. Epub 2017 Nov 8.

From the Center of Neurology, Department of Neurodegenerative Diseases, and Hertie Institute for Clinical Brain Research (K.B., S.L., S.S.D., J.G.S., A.A., A.-K.H., I.L.-S., D.B., T.G., C.S., W.M.), and German Center for Neurodegenerative Diseases (DZNE) (K.B., S.L., A.A., A.-K.H., I.L.-S., T.G., C.S.), University of Tübingen; and Department of Neurology (D.B., W.M.), Christian-Albrechts University, Kiel, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004705DOI Listing
December 2017

Dual-Task Performance in GBA Parkinson's Disease.

Parkinsons Dis 2017 27;2017:8582740. Epub 2017 Jul 27.

Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1155/2017/8582740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551514PMC
July 2017

No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson's disease in nine ADHD candidate SNPs.

Atten Defic Hyperact Disord 2017 Jun 7;9(2):121-127. Epub 2017 Feb 7.

Department of Neurodegeneration, Hertie-Institute of Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s12402-017-0219-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233883PMC
June 2017

Broad clinical phenotype in Parkinsonism associated with a base pair deletion in RAB39B and additional POLG variant.

Parkinsonism Relat Disord 2016 10 15;31:148-150. Epub 2016 Jul 15.

University of Tuebingen, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center of Neurodegenerative Diseases (DZNE), Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.07.005DOI Listing
October 2016

Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs.

Alzheimers Res Ther 2016 10 10;8(1):42. Epub 2016 Oct 10.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe Seyler-Strasse 3, Tuebingen, 72076, Germany.

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http://dx.doi.org/10.1186/s13195-016-0209-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057460PMC
October 2016

Alpha-synuclein gene variants may predict neurostimulation outcome.

Mov Disord 2016 Apr 16;31(4):601-3. Epub 2016 Feb 16.

Department for Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://doi.wiley.com/10.1002/mds.26558
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http://dx.doi.org/10.1002/mds.26558DOI Listing
April 2016

Pilot whole-exome sequencing of a German early-onset Alzheimer's disease cohort reveals a substantial frequency of PSEN2 variants.

Neurobiol Aging 2016 Jan 30;37:208.e11-208.e17. Epub 2015 Sep 30.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.09.016DOI Listing
January 2016

Neurodegenerative CSF markers in genetic and sporadic PD: Classification and prediction in a longitudinal study.

Parkinsonism Relat Disord 2015 Dec 14;21(12):1427-34. Epub 2015 Oct 14.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2015.10.008DOI Listing
December 2015

CHCHD2 and Parkinson's disease.

Lancet Neurol 2015 Jul;14(7):678-9

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Silcherstraße 5, 70276, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00094-0DOI Listing
July 2015

GBA-associated Parkinson's disease: reduced survival and more rapid progression in a prospective longitudinal study.

Mov Disord 2015 Mar 1;30(3):407-11. Epub 2014 Dec 1.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany; Graduate School of Cellular & Molecular Neuroscience, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.26071DOI Listing
March 2015

Comparable autoantibody serum levels against amyloid- and inflammation-associated proteins in Parkinson's disease patients and controls.

PLoS One 2014 21;9(2):e88604. Epub 2014 Feb 21.

Center of Neurology, Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany ; DZNE, German Center for Neurodegenerative Diseases, University of Tuebingen, Tuebingen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088604PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931625PMC
January 2015

In vivo markers of Parkinson's disease and dementia with Lewy bodies: current value of the 5G4 α-synuclein antibody.

Acta Neuropathol 2014 Dec 7;128(6):893-5. Epub 2014 Nov 7.

Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, Center of Neurology, University of Tuebingen, Hoppe Seyler-Strasse 3, 72076, Tuebingen, Germany,

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http://dx.doi.org/10.1007/s00401-014-1364-1DOI Listing
December 2014

SNCA: major genetic modifier of age at onset of Parkinson's disease.

Mov Disord 2013 Aug 14;28(9):1217-21. Epub 2013 May 14.

Department of Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.25469DOI Listing
August 2013

Genetic basis of Parkinson's disease: inheritance, penetrance, and expression.

Appl Clin Genet 2011 1;4:67-80. Epub 2011 Jun 1.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, and German Center for Neurodegenerative Diseases, Tübingen, Germany.

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http://dx.doi.org/10.2147/TACG.S11639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681179PMC
June 2013

Analysis of TGFB1 in European and Japanese Moyamoya disease patients.

Eur J Med Genet 2012 Oct 1;55(10):531-4. Epub 2012 Jun 1.

Department of Neurosurgery, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.ejmg.2012.05.002DOI Listing
October 2012

GBA-associated PD. Neurodegeneration, altered membrane metabolism, and lack of energy failure.

Neurology 2012 Jul 20;79(3):213-20. Epub 2012 Jun 20.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0b013e31825dd369DOI Listing
July 2012

Serum and cerebrospinal fluid uric acid levels in lewy body disorders: associations with disease occurrence and amyloid-β pathway.

J Alzheimers Dis 2011 ;27(1):119-26

Center of Neurology, Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3233/JAD-2011-110587DOI Listing
February 2012

Clinical and brain imaging characteristics in leucine-rich repeat kinase 2-associated PD and asymptomatic mutation carriers.

Mov Disord 2011 Nov 11;26(13):2335-42. Epub 2011 Oct 11.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.23991DOI Listing
November 2011

Neprilysin activity in cerebrospinal fluid is associated with dementia and amyloid-β42 levels in Lewy body disease.

J Alzheimers Dis 2010 ;22(3):933-8

Center of Neurology, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3233/JAD-2010-101197DOI Listing
June 2011

Analysis of ACTA2 in European Moyamoya disease patients.

Eur J Paediatr Neurol 2011 Mar 20;15(2):117-22. Epub 2010 Oct 20.

Department of Neurosurgery, University of Tübingen, Hoppe-Seyler-Str. 3. 72076 Tübingen, Germany.

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http://dx.doi.org/10.1016/j.ejpn.2010.09.002DOI Listing
March 2011

Common genetic polymorphisms in moyamoya and atherosclerotic disease in Europeans.

Childs Nerv Syst 2011 Feb 6;27(2):245-52. Epub 2010 Aug 6.

Department of Neurosurgery, University of Tübingen, Hoppe-Seyler-Strasse 3, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00381-010-1241-8DOI Listing
February 2011

Polymorphisms in TGFB1 and PDGFRB are associated with Moyamoya disease in European patients.

Acta Neurochir (Wien) 2010 Dec 23;152(12):2153-60. Epub 2010 Jun 23.

Department of Neurosurgery, University of Tübingen, Germany.

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http://dx.doi.org/10.1007/s00701-010-0711-9DOI Listing
December 2010

POLG, but not PEO1, is a frequent cause of cerebellar ataxia in Central Europe.

Mov Disord 2010 Nov;25(15):2678-82

Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, and German Research Centre of Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.23286DOI Listing
November 2010

Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease.

Neurobiol Aging 2009 Oct 15;30(10):1706-9. Epub 2008 Feb 15.

Hertie-Institute for Clinical Brain Research, Department of Neurodegenerative Diseases, University of Tuebingen, Hoppe-Seyler Strasse 3, 72076 Tuebingen, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.12.016DOI Listing
October 2009

Effect of genetic variation in Kv1.3 on olfactory function.

Diabetes Metab Res Rev 2009 Sep;25(6):523-7

Medical Clinic, Department of Diabetes, Endocrinology, Nephrology and Angiology, Clinical Chemistry, Eberhard-Karls-University, Tuebingen, Germany.

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http://dx.doi.org/10.1002/dmrr.979DOI Listing
September 2009

Ataxia with ophthalmoplegia or sensory neuropathy is frequently caused by POLG mutations.

Neurology 2009 Sep;73(11):898-900

Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tuebingen, Germany.

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http://dx.doi.org/10.1212/WNL.0b013e3181b78488DOI Listing
September 2009

No differences of butyrylcholinesterase protein activity and allele frequency in Lewy body diseases.

Neurobiol Dis 2009 Aug 27;35(2):296-301. Epub 2009 May 27.

Center of Neurology, Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, University of Tuebingen, Otfried-Müller-Strasse 27, Tuebingen D-72076, Germany.

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http://dx.doi.org/10.1016/j.nbd.2009.05.014DOI Listing
August 2009

The transcription factor PITX3 is associated with sporadic Parkinson's disease.

Neurobiol Aging 2009 May 1;30(5):731-8. Epub 2007 Oct 1.

Hertie-Institute for Clinical Brain Research, Department of Neurodegenerative Diseases, University of Tübingen, Otfried-Müller-Strasse 27, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.08.014DOI Listing
May 2009

A single-nucleotide polymorphism of the osteopontin gene may contribute to a susceptibility to Lewy body disease.

J Neural Transm (Vienna) 2009 May 2;116(5):599-605. Epub 2009 Apr 2.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00702-009-0209-xDOI Listing
May 2009

Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics.

Neurobiol Dis 2009 Apr 31;34(1):107-12. Epub 2008 Dec 31.

Center of Neurology, Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, University of Tuebingen, Germany.

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http://dx.doi.org/10.1016/j.nbd.2008.12.008DOI Listing
April 2009

High frequency of ENG and ALK1/ACVRL1 mutations in German HHT patients.

Hum Mutat 2005 Jun;25(6):595

Department of Otolaryngology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/humu.9345DOI Listing
June 2005

Low pretransplant bone-mineral density and rapid bone loss do not increase risk for avascular osteonecrosis after allogeneic hematopoietic stem cell transplantation.

Transplantation 2005 Jun;79(12):1748-55

Department of Bone Marrow Transplantation, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1097/01.tp.0000164353.86447.dbDOI Listing
June 2005

Avascular osteonecrosis after allogeneic hematopoietic stem-cell transplantation: diagnosis and gender matter.

Transplantation 2004 Oct;78(7):1055-63

Department of Bone Marrow Transplantation, University Hospital of Essen, Germany.

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http://dx.doi.org/10.1097/01.tp.0000138026.40907.38DOI Listing
October 2004

Bone loss following hematopoietic stem cell transplantation: a long-term follow-up.

Blood 2004 May 20;103(10):3635-43. Epub 2003 Nov 20.

Department of Bone Marrow Transplantation, University Hospital of Essen, Essen, Germany.

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http://dx.doi.org/10.1182/blood-2003-09-3081DOI Listing
May 2004

Functional effects of a monoclonal antibody on mechanoelectrical transduction in outer hair cells.

Hear Res 2002 Feb;164(1-2):190-205

Section of Physiological Acoustics and Communication, Department of Otolaryngology, University of Tübingen, Silcherstr. 5, 72076, Germany.

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http://dx.doi.org/10.1016/s0378-5955(01)00431-2DOI Listing
February 2002