Claudia M Denkinger

Claudia M Denkinger

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Claudia M Denkinger

Publications by authors named "Claudia M Denkinger"

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Tuberculosis Diagnosis in Children Using Xpert Ultra on Different Respiratory Specimens.

Am J Respir Crit Care Med 2019 Aug 5. Epub 2019 Aug 5.

University of Capetown, Pediatrics & Child Health, Cape Town, South Africa.

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http://dx.doi.org/10.1164/rccm.201904-0772OCDOI Listing
August 2019

Deriving the optimal limit of detection for an HCV point-of-care test for viraemic infection: Analysis of a global dataset.

J Hepatol 2019 Jul 21;71(1):62-70. Epub 2019 Feb 21.

Boston Medical Center, Section of Infectious Diseases, Boston University School of Public Health, Boston, USA; Department of Epidemiology, Section of Infectious Diseases, Boston University School of Public Health, Boston, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.02.011DOI Listing
July 2019

A systematic review of biomarkers to detect active tuberculosis.

Nat Microbiol 2019 05 25;4(5):748-758. Epub 2019 Feb 25.

FIND, Geneva, Switzerland.

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http://dx.doi.org/10.1038/s41564-019-0380-2DOI Listing
May 2019

Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies.

PLoS Med 2019 Apr 30;16(4):e1002795. Epub 2019 Apr 30.

Center of Infectious Diseases, University of Heidelberg, Heidelberg, Germany.

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http://dx.plos.org/10.1371/journal.pmed.1002795
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http://dx.doi.org/10.1371/journal.pmed.1002795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490887PMC
April 2019

The impact of Xpert MTB/RIF-do we have a final answer?

Lancet Glob Health 2019 Feb;7(2):e161-e162

FIND, 1202 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(18)30493-5DOI Listing
February 2019

New TB Tools Need to be Affordable in the Private Sector: The Case Study of Xpert MTB/RIF.

J Epidemiol Glob Health 2018 12;8(3-4):103-105

McGill International TB Centre, McGill University, Montreal, Canada.

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http://dx.doi.org/10.2991/j.jegh.2018.04.005DOI Listing
December 2018

Can we predict tuberculosis cure? What tools are available?

Eur Respir J 2018 11 8;52(5). Epub 2018 Nov 8.

Dept of Global Health and Amsterdam Institute for Global Health and Development, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01089
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http://dx.doi.org/10.1183/13993003.01089-2018DOI Listing
November 2018

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children.

Pediatr Infect Dis J 2018 10;37(10):e261-e263

Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0000000000001960DOI Listing
October 2018

Xpert MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance.

Cochrane Database Syst Rev 2018 08 27;8:CD012768. Epub 2018 Aug 27.

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1002/14651858.CD012768.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513199PMC
August 2018

Diagnostic Test for Incipient Tuberculosis: A Step Forward, Many More to Go.

Am J Respir Crit Care Med 2018 05;197(9):1106-1107

1 Foundation for Innovative New Diagnostics Geneva, Switzerland.

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http://dx.doi.org/10.1164/rccm.201803-0469EDDOI Listing
May 2018

Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study.

Lancet Infect Dis 2018 01 14;18(1):68-75. Epub 2017 Sep 14.

Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(17)30474-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739874PMC
January 2018

Estimated clinical impact of the Xpert MTB/RIF Ultra cartridge for diagnosis of pulmonary tuberculosis: A modeling study.

PLoS Med 2017 Dec 14;14(12):e1002472. Epub 2017 Dec 14.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730108PMC
December 2017

Implementation of Xpert MTB/RIF in 22 high tuberculosis burden countries: are we making progress?

Eur Respir J 2017 08 31;50(2). Epub 2017 Aug 31.

McGill International TB Centre, McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.1183/13993003.00918-2017DOI Listing
August 2017

Long-lasting tuberculous pleurisy.

Eur Respir J 2017 05 25;49(5). Epub 2017 May 25.

Dept of Epidemiology and Preclinical Research, Translational Research Unit, National Institute for Infectious Diseases "L. Spallanzani", Rome, Italy

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http://dx.doi.org/10.1183/13993003.00356-2017DOI Listing
May 2017

A tuberculosis biomarker database: the key to novel TB diagnostics.

Int J Infect Dis 2017 Mar 31;56:253-257. Epub 2017 Jan 31.

FIND, Chemin des Mines 9, CH-1202 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.ijid.2017.01.025DOI Listing
March 2017

Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis.

Eur Respir J 2016 12 11;48(6):1751-1763. Epub 2016 Nov 11.

Dept of Epidemiology and Preclinical Research, Translational Research Unit, National Institute for Infectious Diseases "L. Spallanzani", Rome, Italy

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http://dx.doi.org/10.1183/13993003.01012-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898936PMC
December 2016

Tuberculosis prevention must integrate technological and basic care innovation.

Eur Respir J 2016 11;48(5):1531-1532

Foundation for Innovative New Diagnostics, Geneva, Switzerland.

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http://dx.doi.org/10.1183/13993003.01601-2016DOI Listing
November 2016

Serial testing for latent tuberculosis using QuantiFERON-TB Gold In-Tube: A Markov model.

Sci Rep 2016 07 29;6:30781. Epub 2016 Jul 29.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.

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http://dx.doi.org/10.1038/srep30781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965809PMC
July 2016

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults.

Cochrane Database Syst Rev 2016 May 10(5):CD011420. Epub 2016 May 10.

Department of Medicine, Division of Infectous Diseases, John Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/14651858.CD011420.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916932PMC
May 2016

Xpert MTB/RIF for tuberculosis testing: access and price in highly privatised health markets.

Lancet Glob Health 2016 Feb;4(2):e94-5

McGill International Tuberculosis Center, McGill University, Montreal, Canada; Department of Epidemiology and Biostatistics, 1020 Pine Avenue West, Montreal QC H3A 1A2, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(15)00269-7DOI Listing
February 2016

Clinical Application of Interferon-γ Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence.

Pathog Immun 2016 4;1(2):308-329. Epub 2016 Jan 4.

Department of Transplant and Infection Immunology, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.20411/pai.v1i2.173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315027PMC
January 2016

Use of chest radiography in the 22 highest tuberculosis burden countries.

Eur Respir J 2015 Dec 24;46(6):1816-9. Epub 2015 Sep 24.

FIND, Geneva, Switzerland

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http://dx.doi.org/10.1183/13993003.01064-2015DOI Listing
December 2015

Defining the needs for next generation assays for tuberculosis.

J Infect Dis 2015 Apr;211 Suppl 2:S29-38

McGill International TB Centre and Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1093/infdis/jiu821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447829PMC
April 2015

Potential market for novel tuberculosis diagnostics: worth the investment?

J Infect Dis 2015 Apr;211 Suppl 2:S58-66

McGill International TB Centre and Department of Epidemiology and Biostatistics, McGill University.

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http://dx.doi.org/10.1093/infdis/jiu817DOI Listing
April 2015

Costs of novel tuberculosis diagnostics--will countries be able to afford it?

J Infect Dis 2015 Apr;211 Suppl 2:S67-77

FIND, Geneva, Switzerland.

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http://dx.doi.org/10.1093/infdis/jiu820DOI Listing
April 2015

Diagnostics for hepatitis C: an urgent need for action.

Lancet Glob Health 2015 Apr;3(4):e195

FIND, 1211 Geneva 20, Switzerland; Shearman & Sterling, London, UK; Symphony Capital LLC, New York, NY, USA.

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http://dx.doi.org/10.1016/S2214-109X(15)70092-6DOI Listing
April 2015

The impact of novel tests for tuberculosis depends on the diagnostic cascade.

Eur Respir J 2014 Nov 3;44(5):1366-9. Epub 2014 Sep 3.

Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

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http://dx.doi.org/10.1183/09031936.00111014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254765PMC
November 2014

Using cerebrospinal fluid for the diagnosis of tuberculous meningitis with GeneXpert.

Eur Respir J 2014 Oct;44(4):1095-6

McGill International TB Centre, McGill University Health Centre, Montreal, Canada Dept of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1183/09031936.00106914DOI Listing
October 2014

Do we need to detect isoniazid resistance in addition to rifampicin resistance in diagnostic tests for tuberculosis?

PLoS One 2014 3;9(1):e84197. Epub 2014 Jan 3.

Department of Epidemiology, Bloomberg School of Public Health, Baltimore, Maryland, United States of America ; Center for Tuberculosis Research, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084197PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880287PMC
September 2014

Reply to El Sahly.

Clin Infect Dis 2014 Sep 22;59(6):912. Epub 2014 May 22.

McGill International Tuberculosis Centre and Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Canada.

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http://dx.doi.org/10.1093/cid/ciu376DOI Listing
September 2014

Modeling the impact of novel diagnostic tests on pediatric and extrapulmonary tuberculosis.

BMC Infect Dis 2014 Sep 3;14:477. Epub 2014 Sep 3.

Beth Israel Deaconess Medical Center, Boston, USA.

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http://dx.doi.org/10.1186/1471-2334-14-477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168123PMC
September 2014

Tuberculosis diagnostics: which target product profiles should be prioritised?

Eur Respir J 2014 Aug 2;44(2):537-40. Epub 2014 Apr 2.

McGill International TB Centre, McGill University, Montreal, QC, Canada Dept of Epidemiology and Biostatistics, McGill University, Montreal, QC, Canada

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http://www.tbfaqs.org/wp-content/uploads/2014/04/Kik-ERJ-201
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http://erj.ersjournals.com/cgi/doi/10.1183/09031936.00027714
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http://dx.doi.org/10.1183/09031936.00027714DOI Listing
August 2014

Replacing smear microscopy for the diagnosis of tuberculosis: what is the market potential?

Eur Respir J 2014 Jun 13;43(6):1793-6. Epub 2014 Feb 13.

McGill International TB Centre, McGill University, Montreal Dept of Epidemiology and Biostatistics, McGill University, Montreal, Canada

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http://erj.ersjournals.com/cgi/doi/10.1183/09031936.00217313
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http://dx.doi.org/10.1183/09031936.00217313DOI Listing
June 2014

Xpert MTB/RIF testing in a low tuberculosis incidence, high-resource setting: limitations in accuracy and clinical impact.

Clin Infect Dis 2014 Apr 14;58(7):970-6. Epub 2014 Jan 14.

McGill International Tuberculosis Centre and Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal.

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https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/
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http://dx.doi.org/10.1093/cid/ciu022DOI Listing
April 2014

Gamma interferon release assays for detection of Mycobacterium tuberculosis infection.

Clin Microbiol Rev 2014 Jan;27(1):3-20

McGill International TB Centre and Department of Epidemiology & Biostatistics, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1128/CMR.00034-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910908PMC
January 2014

Robust, reliable and resilient: designing molecular tuberculosis tests for microscopy centers in developing countries.

Expert Rev Mol Diagn 2013 Nov;13(8):763-7

McGill International TB Centre & Department of Epidemiology & Biostatistics, McGill University, 1020 Pine Ave West, Montreal, QC H3A 1A2, Canada +1 514 398 5422 +1 514 398 4503

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http://dx.doi.org/10.1586/14737159.2013.850034DOI Listing
November 2013

Increased multi-drug resistance among the elderly on admission to the hospital--a 12-year surveillance study.

Arch Gerontol Geriatr 2013 Jan-Feb;56(1):227-30. Epub 2012 Jun 6.

Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02446, USA.

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http://dx.doi.org/10.1016/j.archger.2012.05.006DOI Listing
May 2013

Gamma interferon release assay for monitoring of treatment response for active tuberculosis: an explosion in the spaghetti factory.

J Clin Microbiol 2013 Feb 21;51(2):607-10. Epub 2012 Nov 21.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/JCM.02278-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553895PMC
February 2013

Promise versus reality: optimism bias in package inserts for tuberculosis diagnostics.

J Clin Microbiol 2012 Jul 9;50(7):2455-61. Epub 2012 May 9.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/JCM.00842-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405594PMC
July 2012

Immunodiagnosis of tuberculosis: state of the art.

Med Princ Pract 2012 20;21(1):4-13. Epub 2011 Oct 20.

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, Québec, Canada.

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http://dx.doi.org/10.1159/000331583DOI Listing
April 2012

Point-of-care tuberculosis diagnosis: are we there yet?

Lancet Infect Dis 2012 Mar 17;12(3):169-70. Epub 2011 Oct 17.

Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, USA.

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http://dx.doi.org/10.1016/S1473-3099(11)70257-2DOI Listing
March 2012

Relationship between fear of falling and outcomes of an inpatient geriatric rehabilitation population--fear of the fear of falling.

J Am Geriatr Soc 2010 Apr 22;58(4):664-73. Epub 2010 Mar 22.

Bethesda Geriatric Clinic and Geriatric Competence Center, Zollernring 26, Ulm, Germany.

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http://dx.doi.org/10.1111/j.1532-5415.2010.02759.xDOI Listing
April 2010

Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation.

Cell Immunol 2007 Mar 28;246(1):46-54. Epub 2007 Jun 28.

Institute of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.cellimm.2007.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724065PMC
March 2007

Macrophage migration inhibitory factor and its role in autoimmune diseases.

Arch Immunol Ther Exp (Warsz) 2004 Nov-Dec;52(6):389-400

Institute of Pathology,School of Medicine,Case Western Reserve University,Cleveland,OH 44106, USA.

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February 2005