Publications by authors named "Claude Leclerc"

100Publications

IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8 T-cell responses.

Oncoimmunology 2020 05 12;9(1):1758606. Epub 2020 May 12.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.

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May 2020

Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8 T Cell Responses.

Cell Rep 2019 01;26(5):1242-1257.e7

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, 75015 Paris, France; INSERM U1041, 75015 Paris, France. Electronic address:

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January 2019

Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling.

Cancer Res 2018 06 9;78(11):3014-3026. Epub 2018 Mar 9.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.

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June 2018

Lack of MHC class II molecules favors CD8 T-cell infiltration into tumors associated with an increased control of tumor growth.

Oncoimmunology 2018;7(3):e1404213. Epub 2017 Dec 7.

Département d'immunologie, Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, France.

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December 2017

Feasibility and Accessibility of a Tailored Intervention for Informal Caregivers of People with Severe Psychiatric Disorders: a Pilot Study.

Front Psychiatry 2017 21;8:178. Epub 2017 Sep 21.

Community Psychiatry Service, Department of Psychiatry, University Hospital Centre, Lausanne, Switzerland.

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September 2017

Symptom fluctuations, self-esteem, and cohesion during group cognitive behaviour therapy for early psychosis.

Psychol Psychother 2018 03 14;91(1):15-26. Epub 2017 Jul 14.

Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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March 2018

B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer.

Int J Cancer 2016 09 14;139(6):1358-71. Epub 2016 May 14.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Paris, France.

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September 2016

The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.

Cancer Immunol Immunother 2016 Mar 4;65(3):315-25. Epub 2016 Feb 4.

Unité de Régulation Immunitaire et Vaccinologie, Equipe Labellisée Ligue Contre le Cancer, Institut Pasteur, 25 rue du Docteur Roux, 75015, Paris, France.

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March 2016

Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication.

Cancer Res 2015 Aug 29;75(16):3279-91. Epub 2015 Jun 29.

Institut Pasteur, Immune Regulation and Vaccinology Unit, Equipe Labellisée Ligue Contre le Cancer, Paris, France. INSERM, U1041, Paris, France.

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August 2015

Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells.

J Allergy Clin Immunol 2015 Nov 10;136(5):1355-68.e1-15. Epub 2015 Apr 10.

Unité de Régulation Immunitaire et Vaccinologie, Institut Pasteur, Paris, France; INSERM U1041, Paris, France. Electronic address:

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November 2015

Merging evidence-based psychosocial interventions in schizophrenia.

Behav Sci (Basel) 2014 Nov 6;4(4):437-47. Epub 2014 Nov 6.

Université du Québec à Trois-Rivières, 3351 Boul Des Forges, Trois-Rivières, QC G9A 5H7, Canada.

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November 2014

Understanding process in group cognitive behaviour therapy for psychosis.

Psychol Psychother 2015 Jun 26;88(2):163-77. Epub 2014 Jul 26.

Programme JAP (Jeunes Adultes Psychotiques), Montreal University Hospital Center (CHUM), Montreal, Québec, Canada.

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June 2015

Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach.

Appl Environ Microbiol 2014 Sep 18;80(18):5854-65. Epub 2014 Jul 18.

Section Molecular Microbiology, Department of Molecular Cell Biology, Faculty of Earth and Life Sciences, VU University, Amsterdam, The Netherlands Abera Bioscience AB, Stockholm, Sweden

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September 2014

Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses.

J Immunol 2014 Aug 14;193(4):1787-98. Epub 2014 Jul 14.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris F-75015, France; INSERM, U1041, Paris F-75015, France;

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August 2014

[Evidence-based interventions in psychiatric rehabilitation: which ones should we prioritized and why?].

Can J Psychiatry 2014 Apr;59(4):196-202

Professeur associé, département de sciences infirmières, Université du Québec à Trois-Rivières, Trois-Rivières, Québec; Professeur invité, IUFRS, Université de Lausanne, Lausanne, Suisse.

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April 2014

Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming.

J Immunol 2014 Aug 27;193(3):1151-61. Epub 2014 Jun 27.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris F-75015, France; and INSERM, Unité 1041, Paris F-75015, France

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August 2014

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion.

J Leukoc Biol 2013 Aug 6;94(2):315-23. Epub 2013 Jun 6.

VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, the Netherlands.

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August 2013

Change in jumping to conclusions linked to change in delusions in early psychosis.

Schizophr Res 2013 Jun 3;147(1):207-208. Epub 2013 Apr 3.

Department of Psychiatry, University of British Columbia, Vancouver, Canada; BC Mental Health and Addictions Research Institute, Vancouver, Canada. Electronic address:

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June 2013

Do personality traits matter when choosing a group therapy for early psychosis?

Psychol Psychother 2013 Mar 2;86(1):19-32. Epub 2011 Dec 2.

Department of Psychology, Université de Montréal, Quebec, Canada.

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March 2013

Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice.

Blood 2012 Jul 18;120(1):90-9. Epub 2012 May 18.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Département d'Immunologie, Paris, France.

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July 2012

The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences.

Cancer Res 2012 Jul 9;72(14):3557-69. Epub 2012 May 9.

Institut Pasteur, Immune Regulation and Vaccinology Unit, Department of Immunology, Paris, France.

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July 2012

Group CBT for early psychosis--are there still benefits one year later?

Int J Group Psychother 2012 Apr;62(2):309-21

Department of Psychology at the University of Montreal, Canada.

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April 2012

Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses.

Vaccine 2012 Apr 2;30(18):2848-58. Epub 2012 Mar 2.

Gene Therapy and Hepatology Area and Oncology Area, Center for Applied Medical Research, University of Navarra, 31008 Pamplona, Spain.

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April 2012

Complexes of streptavidin-fused antigens with biotinylated antibodies targeting receptors on dendritic cell surface: a novel tool for induction of specific T-cell immune responses.

Mol Biotechnol 2012 Jul;51(3):221-32

Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the ASCR, Videnska 1083, 14220 Prague, Czech Republic.

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July 2012

[Evaluation of the mental condition. How are you today?].

Perspect Infirm 2011 Mar-Apr;8(2):29-31

Département des sciences infirmières de l'Université du Québec à Trois-Rivières et chercheuse boursière FRSQ-FRESIQ.

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May 2011

Personality traits in early psychosis: relationship with symptom and coping treatment outcomes.

Early Interv Psychiatry 2011 Feb 12;5(1):33-40. Epub 2010 Aug 12.

Department of Psychology, University of Montreal, Montreal, Quebec, Canada.

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February 2011

Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses.

J Biol Chem 2011 Mar 30;286(10):7797-811. Epub 2010 Dec 30.

Institut Pasteur, Department of Immunology, Immune Regulation and Vaccinology Unit, 75015 Paris, France.

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March 2011

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis.

Vaccine 2010 Oct 15;28(44):7146-54. Epub 2010 Sep 15.

University of Navarra, Centre for Applied Medical Research (CIMA), Gene Therapy and Hepatology Area, Pamplona 31008, Spain.

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October 2010

The process of recovery of people with mental illness: the perspectives of patients, family members and care providers: part 1.

BMC Health Serv Res 2010 Jun 11;10:161. Epub 2010 Jun 11.

Research Centre of the University of Montreal Hospital Centre, Masson Building, 3850 Saint Urbain Street, Montreal, Quebec H2W 1T7, Canada.

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June 2010

Towards a rational approach to vaccine development.

Authors:
Claude Leclerc

Hum Vaccin 2010 Apr 17;6(4):292-6. Epub 2010 Apr 17.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris, France.

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April 2010

Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils.

Immunity 2009 Nov 12;31(5):761-71. Epub 2009 Nov 12.

Institut Pasteur, Unité Régulation Immunitaire et Vaccinologie, 25 rue du Dr. Roux, 75724 Paris Cedex 15, France.

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November 2009

Change in delusions is associated with change in "jumping to conclusions".

Psychiatry Res 2009 Dec 10;170(2-3):124-7. Epub 2009 Nov 10.

Department of Psychiatry, University of British Columbia, Vancouver, Canada.

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December 2009

Religion and spirituality: how clinicians in quebec and geneva cope with the issue when faced with patients suffering from chronic psychosis.

Community Ment Health J 2010 Feb 22;46(1):77-86. Epub 2009 Sep 22.

Division of Adult Psychiatry, University Hospital of Geneva and University of Geneva, Rue du 31-Décembre 36, 1207, Geneva, Switzerland.

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February 2010

Developing a model of recovery in mental health.

BMC Health Serv Res 2009 May 1;9:73. Epub 2009 May 1.

Faculté des Sciences Infirmières, Université de Montréal, 2375 Chemin de la Côte Sainte-Catherine, CP 6128, succursale A, Montréal, Québec, Canada.

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May 2009

Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation.

Blood 2008 Nov 12;112(9):3713-22. Epub 2008 Aug 12.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris, France.

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November 2008

Regulatory B and T cells in infections.

Microbes Infect 2008 Jul 10;10(9):1030-5. Epub 2008 Jul 10.

Unité de Régulation Immunitaire et Vaccinologie, Institut Pasteur, 75724 Paris Cedex 15, France.

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July 2008

Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis.

PLoS One 2008 Jul 30;3(7):e2833. Epub 2008 Jul 30.

Unité de Régulation Immunitaire et Vaccinologie, Institut Pasteur, Paris, France.

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July 2008

Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions.

J Neuroimmunol 2008 Jun 20;197(1):74-80. Epub 2008 May 20.

Institut Pasteur, Repliement et Modélisation des Protéines, Dpt Biologie Structurale et Chimie, 25 rue du Dr Roux, F-75015, Paris, France.

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June 2008

Immobilized cytokines as biomaterials for manufacturing immune cell based vaccines.

J Biomed Mater Res A 2008 Sep;86(4):1033-40

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, F-75015 Paris, France.

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September 2008

Personality characteristics and attachment in first episode psychosis: impact on social functioning.

J Nerv Ment Dis 2007 Aug;195(8):631-9

Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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August 2007

Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells.

J Exp Med 2007 May 7;204(5):1107-18. Epub 2007 May 7.

Unité Régulation Immunitaire et Vaccinologie and 4Immunobiologie des Cellules Dendritiques, Institut Pasteur, Paris, Cedex 15, France.

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May 2007

Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia.

Cogn Neuropsychiatry 2007 Mar;12(2):112-27

Department of Psychiatry, Centre de Recherche Fernand-Seguin, Hôpital Louis-H. Lafontaine, Université de Montréal, Quebec, Canada.

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March 2007

[New technologies for vaccine development].

Authors:
Claude Leclerc

Med Sci (Paris) 2007 Apr;23(4):386-90

Unité de Régulation Immunitaire et Vaccinologie, Institut Pasteur, 25, rue du Docteur Roux, 75015 Paris, France et Inserm, U833, Paris, France.

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April 2007

TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help.

Blood 2007 Jun 5;109(12):5318-26. Epub 2007 Mar 5.

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris, France.

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June 2007

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN.

J Immunol 2007 Feb;178(4):2361-9

Institut Pasteur, Unité de Régulation Immunitaire et Vaccinologie, Paris, France.

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February 2007

Carbohydrate antigens: synthesis aspects and immunological applications in cancer.

Mini Rev Med Chem 2006 Dec;6(12):1357-73

CNRS, URA2128, Unité de Chimie Organique, Paris, France.

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December 2006

[Analysis of in vitro delivering CD8+ T epitopes by attenuated bacteria].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 Nov;22(6):730-3

Animal Infectious Diseases Laboratory of Ministry of Agriculture, Yangzhou University, Yangzhou 225009, China.

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November 2006

Fetal spleen stroma drives macrophage commitment.

Development 2006 Sep 16;133(18):3619-28. Epub 2006 Aug 16.

Unité du Développement des Lymphocytes, INSERM U668, Institut Pasteur, 25, Rue du Dr Roux, 75724 Paris cedex 15, France.

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September 2006

Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells.

J Virol 2006 May;80(10):4656-63

Neurovirologie et Régénération du Système Nerveux, Department de Neurosciences, Repliement et Modélisation des Protéines, Dpt Biologie Structurale et Chimie, Biologie des Régulations Immunaires, INSERM E352, 75015 Paris, France.

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May 2006

Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.

Glycobiology 2006 May 31;16(5):390-401. Epub 2006 Jan 31.

Unité de Chimie Organique URA CNRS 2128, Institut Pasteur, Paris, France.

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May 2006

Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo.

Int Immunol 2006 Mar 13;18(3):445-52. Epub 2006 Jan 13.

Institut Pasteur, Unité de Biologie des Régulations Immunitaires, Paris, France.

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March 2006

[Group interventions for people with refractory psychosis].

Sante Ment Que 2005 ;30(1):97-115

University of British Columbia, Vancouver.

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October 2005

Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs.

Immunity 2005 Apr;22(4):467-77

Unité de Biologie des Régulations Immunitaires, INSERM E352, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris, Cedex 15, France.

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April 2005

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system.

J Immunol 2005 Mar;174(6):3570-9

Unité de Biologie des Régulations Immunitaires, Institut Pasteur, Institut National de la Santé et de la Recherche Médicale Equipe 352, Paris, France.

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March 2005

Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal.

J Immunol 2005 Mar;174(6):3432-9

Unité de Biologie des Régulations Immunitaires, Institut Pasteur, Institut National de la Santé et de la Recherche Médicale E352, Paris, France.

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March 2005

Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein.

Cancer Res 2005 Jan;65(2):641-9

BT PHARMA, Biotop, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale E352, Institut Pasteur, Paris Cedex 15, France.

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January 2005

Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo.

Vaccine 2004 Dec;23(5):604-14

Unité de Biologie des Régulations Immunitaires, INSERM E 352, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.

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December 2004