Publications by authors named "Clare L Scott"

62Publications

RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of -Null Cancers.

Cancer Res 2020 Jul 25;80(13):2848-2860. Epub 2020 Mar 25.

Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-3033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335334PMC
July 2020

Genomics of gynaecological carcinosarcomas and future treatment options.

Semin Cancer Biol 2020 04 14;61:110-120. Epub 2019 Oct 14.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria, 3010, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, 3010, Australia; Royal Women's Hospital, Parkville, Victoria, 3052, Australia; Royal Melbourne Hospital, Parkville, Victoria, 3050, Australia; Peter MacCallum Cancer Centre, Grattan Street, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1016/j.semcancer.2019.10.006DOI Listing
April 2020

Diverse mechanisms of PARP inhibitor resistance in ovarian cancer.

Biochim Biophys Acta Rev Cancer 2019 12 2;1872(2):188307. Epub 2019 Aug 2.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, Victoria 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2019.08.002DOI Listing
December 2019

Preclinical rare cancer research to inform clinical trial design.

Nat Rev Cancer 2019 09;19(9):481-482

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/s41568-019-0172-2DOI Listing
September 2019

Clarifying the role of EMSY in DNA repair in ovarian cancer.

Cancer 2019 08 2;125(16):2720-2724. Epub 2019 Jun 2.

Cancer Biology and Stem Cells Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/cncr.32135DOI Listing
August 2019

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.

Cell Death Dis 2018 05 23;9(6):618. Epub 2018 May 23.

Development and Stem Cells Program, Monash Biomedicine Discovery Institute, and Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1038/s41419-018-0633-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966424PMC
May 2018

Targeting DNA repair: the genome as a potential biomarker.

J Pathol 2018 04 10;244(5):586-597. Epub 2018 Feb 10.

Imperial College, London, UK.

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http://doi.wiley.com/10.1002/path.5025
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http://dx.doi.org/10.1002/path.5025DOI Listing
April 2018

Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics.

Gynecol Oncol 2017 04 3;145(1):130-136. Epub 2017 Feb 3.

Parkville Familial Cancer Centre, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Grattan Street, Parkville, Victoria 3050, Australia; Department of Medical Oncology, Peter MacCallum Cancer Centre, Grattan Street, Melbourne, Victoria 3050, Australia; The University of Melbourne, Melbourne, Victoria 3010, Australia; Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1016/j.ygyno.2017.01.030DOI Listing
April 2017

BCL2-modifying factor promotes germ cell loss during murine oogenesis.

Reproduction 2016 May 25;151(5):553-62. Epub 2016 Feb 25.

Development and Stem Cells ProgramMonash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia

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http://dx.doi.org/10.1530/REP-15-0561DOI Listing
May 2016

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.

Cell Rep 2016 Mar 18;14(8):1858-66. Epub 2016 Feb 18.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.01.059DOI Listing
March 2016

Poly (ADP-ribose) polymerase inhibitors: recent advances and future development.

J Clin Oncol 2015 Apr 16;33(12):1397-406. Epub 2015 Mar 16.

Clare L. Scott, Walter and Eliza Hall Institute of Medical Research and Royal Melbourne Hospital, Parkville, Victoria, Australia; Elizabeth M. Swisher, University of Washington, Seattle, WA; and Scott H. Kaufmann, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2014.58.8848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517072PMC
April 2015

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.

Development 2014 Aug 18;141(16):3159-64. Epub 2014 Jul 18.

ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia

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http://dx.doi.org/10.1242/dev.108498DOI Listing
August 2014

PUMA regulates germ cell loss and primordial follicle endowment in mice.

Reproduction 2014 Aug 23;148(2):211-9. Epub 2014 May 23.

MIMR-PHI Institute of Medical Research27-31 Wright Street, Clayton, Victoria 3168, AustraliaDepartment of Anatomy and Developmental BiologyMonash University, Clayton, Victoria, AustraliaThe Walter and Eliza Hall Institute of Medical ResearchMelbourne, Victoria, AustraliaDepartment of Medical BiologyThe University of Melbourne, Melbourne, Victoria, AustraliaMIMR-PHI Institute of Medical Research27-31 Wright Street, Clayton, Victoria 3168, AustraliaDepartment of Anatomy and Developmental BiologyMonash University, Clayton, Victoria, AustraliaThe Walter and Eliza Hall Institute of Medical ResearchMelbourne, Victoria, AustraliaDepartment of Medical BiologyThe University of Melbourne, Melbourne, Victoria, Australia

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http://www.reproduction-online.org/content/early/2014/05/23/
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http://www.reproduction-online.org/cgi/doi/10.1530/REP-13-06
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http://dx.doi.org/10.1530/REP-13-0666DOI Listing
August 2014

Patient-derived xenograft models in gynecologic malignancies.

Am Soc Clin Oncol Educ Book 2014 :e258-66

From The Walter and Eliza Hall Institute of Medical Research and Royal Women's Hospital, Parkville, Victoria, Australia; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre/University of Toronto, Toronto, Canada; Department of Oncology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156101PMC
November 2015

Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts.

Mol Oncol 2014 May 24;8(3):656-68. Epub 2014 Jan 24.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Royal Women's Hospital, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400120PMC
May 2014

Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment.

Front Oncol 2013 Dec 4;3:295. Epub 2013 Dec 4.

The Kinghorn Cancer Centre, St Vincent's Clinical School, Garvan Institute of Medical Research , Sydney, NSW , Australia.

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http://dx.doi.org/10.3389/fonc.2013.00295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849703PMC
December 2013

Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice.

Blood 2013 Oct 21;122(14):2402-11. Epub 2013 Aug 21.

Centre Méditerranéen de Médecine Moléculaire (C3M), équipe "contrôle métabolique des morts cellulaires," Institut national de la santé et de la recherche médicale (Inserm) U1065, Nice, France;

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http://dx.doi.org/10.1182/blood-2013-01-478651DOI Listing
October 2013

p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

Cell Rep 2013 May 9;3(5):1339-45. Epub 2013 May 9.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1016/j.celrep.2013.04.012DOI Listing
May 2013

Emotion processing and social participation following stroke: study protocol.

BMC Neurol 2012 Jul 17;12:56. Epub 2012 Jul 17.

Rowett Institute, Greenburn Road, University of Aberdeen, Aberdeen AB21 9SB, UK.

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http://dx.doi.org/10.1186/1471-2377-12-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464671PMC
July 2012

CART-WHEEL.org can facilitate research into rare gynecological tumors.

Int J Gynecol Cancer 2011 Dec;21(9):1517-9

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http://dx.doi.org/10.1097/IGC.0b013e3182255152DOI Listing
December 2011

Mental practice with motor imagery in stroke recovery: randomized controlled trial of efficacy.

Brain 2011 May 22;134(Pt 5):1373-86. Epub 2011 Apr 22.

Department of Psychology, School of Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.

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http://dx.doi.org/10.1093/brain/awr077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097892PMC
May 2011

Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.

Cancer Res 2011 May 11;71(10):3603-15. Epub 2011 Mar 11.

Gene Regulation Laboratory, Cancer Therapeutics Program, The Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3289DOI Listing
May 2011

Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance.

Blood 2010 Oct 14;116(17):3197-207. Epub 2010 Jul 14.

Molecular Genetics of CancerDivision, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3052, Victoria, Australia.

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http://dx.doi.org/10.1182/blood-2010-04-281071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995351PMC
October 2010

Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

Diabetes 2009 Oct 6;58(10):2316-23. Epub 2009 Jul 6.

Department of Microbiology and Immunology, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.2337/db08-1602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750233PMC
October 2009

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics.

Nat Rev Cancer 2009 May 3;9(5):321-6. Epub 2009 Apr 3.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.

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http://www.nature.com/articles/nrc2615
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http://dx.doi.org/10.1038/nrc2615DOI Listing
May 2009

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas.

Proc Natl Acad Sci U S A 2008 Nov 11;105(46):17961-6. Epub 2008 Nov 11.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia.

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http://dx.doi.org/10.1073/pnas.0809957105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582212PMC
November 2008

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic.

J Clin Invest 2008 Nov 23;118(11):3651-9. Epub 2008 Oct 23.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1172/JCI35437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571034PMC
November 2008

Longitudinal aspects of emotion recognition in patients with traumatic brain injury.

Neuropsychologia 2008 Jan 9;46(1):148-59. Epub 2007 Aug 9.

School of Psychology and Sport Sciences, University of Northumbria, Northumberland Building, Newcastle-upon-Tyne NE1 8ST, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S002839320700280
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http://dx.doi.org/10.1016/j.neuropsychologia.2007.08.002DOI Listing
January 2008

Recovery of hand function through mental practice: a study protocol.

BMC Neurol 2006 Oct 26;6:39. Epub 2006 Oct 26.

School of Psychology and Sport Sciences, Northumbria University, Northumberland Building, Newcastle upon Tyne NE1 8ST, UK.

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http://dx.doi.org/10.1186/1471-2377-6-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635559PMC
October 2006

The utility of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography in the investigation of patients with disseminated carcinoma of unknown primary origin.

Mol Imaging Biol 2005 May-Jun;7(3):236-43

Division of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, East Melbourne, Victoria, 8006, Australia.

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http://dx.doi.org/10.1007/s11307-005-4114-xDOI Listing
September 2005