Publications by authors named "Clara Soares"

2 Publications

  • Page 1 of 1

Late stillbirth: a ten year cohort study.

Acta Med Port 2013 Jan-Feb;26(1):39-42. Epub 2013 Apr 24.

Department of Obstetrics and Gynecology, Alfredo da Costa Maternity, Lisbon, Portugal.

Introduction: Late fetal death is a desolating event that inspite the effort to implement new surveillance protocols in perinatal continues to defy our clinical pratice.

Objective: To examine etiological factors contributing to main causes and conditions associated with fetal death in late pregnancies over a 10-year period.

Methods: Retrospective cohort analysis of 208 late singleton stillbirth delived in a tertiary-perinatal referral maternity over a 10-year period. Clinical charts, laboratory data and feto-placental pathology findings were systematically reviewed.

Results: The incidence of late fetal demise was 3.5 per 1000 pregnancies. No significant trend in the incidence of stillbirth was demonstrated during the study period. Stillbirth was intrapartum in 12 (5.8%) cases and 72 (35%) were term pregnancies. Fourteen percent of cases were undersurveilled pregnancies. Mean gestacional age at diagnosis was 34 weeks. The primary cause of death was fetal, it was present in 59 cases, 25% were considered small for gestational age. Stillbirths were unexplained in 24.5% of cases. Maternal medical disorders were identified in 21%. Hypertensive disorders were frequent and associated with early gestacional age (p = 0.028).

Conclusion: There was no change in the incidence of late stillbirth during the 10 years under evaluation. The incidence was 3.5 ‰ which was identical to that described in developed countries. About one quarter of the stillbirths was unexplained. The most frequent maternal pathology was chronic hypertension.
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April 2014

[Prophylaxis of RhD isoimmunization: a proposal of management].

Acta Med Port 2003 Jul-Aug;16(4):255-60

Serviço de Medicina Materno-Fetal, Maternidade Dr. Alfredo da Costa, Lisboa.

Isoimmunisation RhD has an important perinatal morbidity and mortality. Since prophylaxis was introduced in the sixties, the incidence of haemolytic disease of the newborn has decreased. When administred in due time and in the right dosage anti-D immunoglobulin can prevent sensibilization. Nevertheless new cases continue to occur, underlying the need for an urgent improvement of our conduct. The purpose of this review is to provide an overview of the pathology of RhD isoimmunization and of aspects involved in its prophylaxis.
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May 2012