Publications by authors named "Clara Abraham"

77Publications

TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants.

Cell Mol Gastroenterol Hepatol 2020 Aug 19. Epub 2020 Aug 19.

Department of Internal Medicine, Yale University, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2020.08.003DOI Listing
August 2020

Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation.

Gastroenterology 2020 Sep 18;159(3):1051-1067. Epub 2020 Jul 18.

Department of Internal Medicine, Yale University, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.07.024DOI Listing
September 2020

Disease Risk-Associated Genetic Variants in and Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages.

J Immunol 2020 Sep 13;205(5):1406-1418. Epub 2020 Jul 13.

Department of Internal Medicine, Yale University, New Haven, CT 06520

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http://dx.doi.org/10.4049/jimmunol.1901112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510936PMC
September 2020

IL23 Promotes Antimicrobial Pathways in Human Macrophages, Which Are Reduced With the IBD-Protective IL23R R381Q Variant.

Cell Mol Gastroenterol Hepatol 2020 29;10(4):673-697. Epub 2020 May 29.

Section of Digestive Diseases, Department of Internal Medicine, Yale University, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2020.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490566PMC
May 2020

LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes.

Cell Rep 2019 12;29(13):4525-4539.e4

Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372507PMC
December 2019

Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Mucosal Immunol 2019 Jul;12(4):1065

Department of Internal Medicine, Yale University, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1038/s41385-019-0179-8DOI Listing
July 2019

Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Mucosal Immunol 2019 07 3;12(4):874-887. Epub 2019 May 3.

Department of Internal Medicine, Yale University, New Haven, CT, 06510, USA.

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http://www.nature.com/articles/s41385-019-0165-1
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http://dx.doi.org/10.1038/s41385-019-0165-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688861PMC
July 2019

Twist1 and Twist2 Induce Human Macrophage Memory upon Chronic Innate Receptor Treatment by HDAC-Mediated Deacetylation of Cytokine Promoters.

J Immunol 2019 06 26;202(11):3297-3308. Epub 2019 Apr 26.

Department of Internal Medicine, Yale University, New Haven, CT 06510

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http://dx.doi.org/10.4049/jimmunol.1800757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615459PMC
June 2019

IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and Immune-Mediated Disease Risk Variants Modulate This Outcome.

J Immunol 2019 02 28;202(3):920-930. Epub 2018 Dec 28.

Department of Internal Medicine, Yale University, New Haven, CT 06520; and

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http://dx.doi.org/10.4049/jimmunol.1800226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585431PMC
February 2019

INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling.

Elife 2018 10 25;7. Epub 2018 Oct 25.

Division of Gastroenterology, Nutrition and Hepatology, Boston Children's Hospital, Boston, United States.

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https://elifesciences.org/articles/38539
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http://dx.doi.org/10.7554/eLife.38539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226287PMC
October 2018

Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes.

Nat Commun 2017 06 8;8:15614. Epub 2017 Jun 8.

Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.1038/ncomms15614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472760PMC
June 2017

Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases.

Gastroenterology 2017 02 22;152(2):374-388.e4. Epub 2016 Oct 22.

Division of Gastroenterology, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1053/j.gastro.2016.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287922PMC
February 2017

JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages.

J Immunol 2016 11 23;197(9):3695-3704. Epub 2016 Sep 23.

Section of Digestive Diseases, Department of Internal Medicine, Yale University, New Haven, CT 06520

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http://dx.doi.org/10.4049/jimmunol.1600845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127452PMC
November 2016

IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation.

Cell Rep 2016 08 18;16(9):2442-55. Epub 2016 Aug 18.

Department of Internal Medicine, Yale University, New Haven, CT 06510, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247163099
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http://dx.doi.org/10.1016/j.celrep.2016.07.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165654PMC
August 2016

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF.

Gastroenterology 2016 10 1;151(4):710-723.e2. Epub 2016 Jul 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037012PMC
October 2016

T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo.

J Immunol 2015 May 23;194(9):4122-9. Epub 2015 Mar 23.

Department of Internal Medicine, Yale University, New Haven, CT 06510

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401328
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http://dx.doi.org/10.4049/jimmunol.1401328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404034PMC
May 2015

TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages.

J Immunol 2015 Feb 7;194(4):1928-37. Epub 2015 Jan 7.

Section of Digestive Diseases, Department of Internal Medicine, Yale University, New Haven, CT 06520

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http://dx.doi.org/10.4049/jimmunol.1401933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323761PMC
February 2015

A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13451-6. Epub 2014 Sep 2.

Department of Internal Medicine, Yale University, New Haven, CT 06510

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http://www.pnas.org/lookup/doi/10.1073/pnas.1404178111
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http://dx.doi.org/10.1073/pnas.1404178111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169936PMC
September 2014

Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages.

Gastroenterology 2014 Oct 21;147(4):835-46. Epub 2014 Jun 21.

Department of Internal Medicine, Yale University, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170054PMC
October 2014

Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele.

Immunity 2014 May;40(5):734-46

Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157904PMC
May 2014

NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury.

J Immunol 2014 Apr 3;192(7):3409-18. Epub 2014 Mar 3.

Department of Medicine, Yale University School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.4049/jimmunol.1302436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064676PMC
April 2014

NF-κB1 inhibits NOD2-induced cytokine secretion through ATF3-dependent mechanisms.

Mol Cell Biol 2013 Dec 7;33(24):4857-71. Epub 2013 Oct 7.

Department of Medicine, Yale University, New Haven, Connecticut, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00797-13
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http://dx.doi.org/10.1128/MCB.00797-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889551PMC
December 2013

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

Gastroenterology 2013 Aug 22;145(2):407-15. Epub 2013 Apr 22.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1053/j.gastro.2013.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722284PMC
August 2013

Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells.

PLoS One 2013 1;8(3):e57746. Epub 2013 Mar 1.

Department of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585933PMC
August 2013

NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation.

Am J Physiol Gastrointest Liver Physiol 2013 Mar 3;304(6):G583-96. Epub 2013 Jan 3.

Department of Internal Medicine, Yale University, New Haven, CT 06520, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.00297.2012
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http://dx.doi.org/10.1152/ajpgi.00297.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602688PMC
March 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines.

Gastroenterology 2012 Dec 8;143(6):1530-43. Epub 2012 Sep 8.

Department of Medicine, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1053/j.gastro.2012.08.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618474PMC
December 2012

CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells.

Am J Physiol Gastrointest Liver Physiol 2012 Oct 19;303(7):G851-60. Epub 2012 Jul 19.

Department of Medicine, Yale University, 333 Cedar St., 1080 LMP, New Haven, CT 06520, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.00520.2011
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http://dx.doi.org/10.1152/ajpgi.00520.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469592PMC
October 2012

Effector CD4+ T cell expression signatures and immune-mediated disease associated genes.

PLoS One 2012 8;7(6):e38510. Epub 2012 Jun 8.

Department of Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371029PMC
February 2015

Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages.

J Biol Chem 2011 Jul 9;286(30):26440-9. Epub 2011 Jun 9.

Department of Internal Medicine, Yale University, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.1074/jbc.M111.237495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143608PMC
July 2011

Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses.

Proc Natl Acad Sci U S A 2011 Jun 23;108(23):9560-5. Epub 2011 May 23.

Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.1017854108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111257PMC
June 2011

Secretory mediators regulate Nod2-induced tolerance in human macrophages.

Gastroenterology 2011 Jan 18;140(1):231-41. Epub 2010 Sep 18.

Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085100132
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http://dx.doi.org/10.1053/j.gastro.2010.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145247PMC
January 2011

Pathway analysis comparison using Crohn's disease genome wide association studies.

BMC Med Genomics 2010 Jun 28;3:25. Epub 2010 Jun 28.

Robert S Boas Center for Human Genetics and Genomics, Feinstein Institute for Medical Research, Manhasset, New York, USA.

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http://dx.doi.org/10.1186/1755-8794-3-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908056PMC
June 2010

Unraveling the genetics of autoimmunity.

Cell 2010 Mar;140(6):791-7

Department of Immunobiology, Yale University, New Haven, CT 06520, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674100023
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http://dx.doi.org/10.1016/j.cell.2010.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491807PMC
March 2010

Inflammatory bowel disease.

N Engl J Med 2009 Nov;361(21):2066-78

Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMra0804647
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http://dx.doi.org/10.1056/NEJMra0804647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491806PMC
November 2009

Interleukin-23/Th17 pathways and inflammatory bowel disease.

Inflamm Bowel Dis 2009 Jul;15(7):1090-100

Department of Medicine, Digestive Diseases, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1002/ibd.20894DOI Listing
July 2009

IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease.

Annu Rev Med 2009 ;60:97-110

Section of Digestive Diseases, Departments of 1Medicine, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1146/annurev.med.60.051407.123757DOI Listing
September 2009

A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis.

Nat Clin Pract Gastroenterol Hepatol 2008 Mar 29;5(3):172-6. Epub 2008 Jan 29.

Yale University School of Medicine, Department of Internal Medicine, Section of Digestive Diseases, 333 Cedar St/1080 LMP, PO Box 208019, New Haven, CT 06520-8019, USA.

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http://www.nature.com/doifinder/10.1038/ncpgasthep1055
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http://dx.doi.org/10.1038/ncpgasthep1055DOI Listing
March 2008

Chronic stimulation of Nod2 mediates tolerance to bacterial products.

Proc Natl Acad Sci U S A 2007 Dec 21;104(49):19440-5. Epub 2007 Nov 21.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0706097104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148308PMC
December 2007

Bugging of the intestinal mucosa.

N Engl J Med 2007 Aug;357(7):708-10

Department of Medicine, University of Chicago, Chicago, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMcibr073420
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http://dx.doi.org/10.1056/NEJMcibr073420DOI Listing
August 2007

CD18 is required for intestinal T cell responses at multiple immune checkpoints.

J Immunol 2007 Feb;178(4):2104-12

Section of Gastroenterology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.4049/jimmunol.178.4.2104DOI Listing
February 2007

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

Science 2006 Dec 26;314(5804):1461-3. Epub 2006 Oct 26.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C-Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1126/science.1135245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410764PMC
December 2006

IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction.

Gastroenterology 2006 Oct 22;131(4):1153-63. Epub 2006 Aug 22.

State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1053/j.gastro.2006.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693969PMC
October 2006

Inflammatory bowel disease genetics: Nod2.

Annu Rev Med 2007 ;58:401-16

Department of Medicine, Yale University, New Haven, Connecticut 06510, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.med.58.0617
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http://dx.doi.org/10.1146/annurev.med.58.061705.145024DOI Listing
April 2007

Functional consequences of NOD2 (CARD15) mutations.

Inflamm Bowel Dis 2006 Jul;12(7):641-50

Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, Illinois 60637, USA.

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https://academic.oup.com/ibdjournal/article/12/7/641-650/468
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http://dx.doi.org/10.1097/01.MIB.0000225332.83861.5fDOI Listing
July 2006

CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells.

J Immunol 2005 Dec;175(12):7889-97

Department of Medicine, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.4049/jimmunol.175.12.7889DOI Listing
December 2005

Inducing intestinal growth.

N Engl J Med 2005 Nov;353(21):2297-9

Department of Medicine, University of Chicago, Chicago, USA.

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http://dx.doi.org/10.1056/NEJMcibr053367DOI Listing
November 2005

The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.

J Immunol 2005 Jun;174(12):8173-82

Department of Pathology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.4049/jimmunol.174.12.8173DOI Listing
June 2005

LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo.

J Immunol 2004 Oct;173(7):4443-51

Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.4049/jimmunol.173.7.4443DOI Listing
October 2004

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

Hum Mol Genet 2004 Aug 15;13(16):1715-25. Epub 2004 Jun 15.

The Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, The University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh182DOI Listing
August 2004