Claes Ohlsson

Claes Ohlsson

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Claes Ohlsson

Publications by authors named "Claes Ohlsson"

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Wnt16 Overexpression in Osteoblasts Increases the Subchondral Bone Mass but has no Impact on Osteoarthritis in Young Adult Female Mice.

Calcif Tissue Int 2020 Jul 5;107(1):31-40. Epub 2020 Mar 5.

Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00223-020-00682-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270053PMC
July 2020

Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study.

Scand J Public Health 2020 Jun 29;48(4):436-441. Epub 2018 Sep 29.

Clinical and Molecular Osteoporosis Research Unit, Department of Orthopedics and Clinical Sciences, Lund University, Skåne University Hospital, Sweden.

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http://dx.doi.org/10.1177/1403494818801628DOI Listing
June 2020

Early puberty and risk for type 2 diabetes in men.

Diabetologia 2020 Jun 23;63(6):1141-1150. Epub 2020 Mar 23.

Centre for Bone and Arthritis Research, Institute of Medicine, the Sahlgrenska Academy at University of Gothenburg, Klinfarmlab, Vita Stråket 11, Sahlgrenska University Hospital, S-413 45, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00125-020-05121-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228987PMC
June 2020

Growth and Pubertal Timing in Boys With Adult-diagnosed Celiac Disease: A Population-based Longitudinal Cohort Study.

J Pediatr Gastroenterol Nutr 2020 Jun;70(6):853-857

Centre for Bone and Arthritis Research, Sahlgrenska Academy at the University of Gothenburg.

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http://dx.doi.org/10.1097/MPG.0000000000002682DOI Listing
June 2020

The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual maturation.

Am J Physiol Endocrinol Metab 2020 May 3;318(5):E646-E654. Epub 2020 Mar 3.

Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00018.2020DOI Listing
May 2020

Increased weight loading reduces body weight and body fat in obese subjects - A proof of concept randomized clinical trial.

EClinicalMedicine 2020 May 30;22:100338. Epub 2020 Apr 30.

Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.eclinm.2020.100338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264953PMC
May 2020

Pasteurized protects from fat mass gain but not from bone loss.

Am J Physiol Endocrinol Metab 2020 Apr 21;318(4):E480-E491. Epub 2020 Jan 21.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00425.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191407PMC
April 2020

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure.

J Clin Endocrinol Metab 2020 Apr;105(4)

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/clinem/dgaa082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069346PMC
April 2020

Childhood body mass index is associated with the risk of adult hematologic malignancies in men-The best Gothenburg cohort.

Int J Cancer 2020 Apr 19. Epub 2020 Apr 19.

Centre for Bone and Arthritis Research, Institute of Medicine, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/ijc.33015DOI Listing
April 2020

Smoking-Induced Risk of Osteoporosis Is Partly Mediated by Cadmium From Tobacco Smoke: The MrOS Sweden Study.

J Bone Miner Res 2020 Mar 19. Epub 2020 Mar 19.

Department of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.4014DOI Listing
March 2020

High Plasma Erythropoietin Predicts Incident Fractures in Elderly Men with Normal Renal Function: The MrOS Sweden Cohort.

J Bone Miner Res 2020 Feb 20;35(2):298-305. Epub 2019 Nov 20.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3900DOI Listing
February 2020

Altered body composition profiles in young adults with childhood-onset inflammatory bowel disease.

Scand J Gastroenterol 2020 Feb 1;55(2):169-177. Epub 2020 Feb 1.

Department of Pediatrics, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg and The Queen Silvia Children's Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1080/00365521.2020.1716061DOI Listing
February 2020

High Fidelity of Mouse Models Mimicking Human Genetic Skeletal Disorders.

Front Endocrinol (Lausanne) 2019 4;10:934. Epub 2020 Feb 4.

Department of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.3389/fendo.2019.00934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010808PMC
February 2020

Pubertal BMI change and adult-onset asthma in men: Population-based cohort study in Sweden.

Clin Exp Allergy 2020 Jan 4;50(1):51-60. Epub 2019 Dec 4.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/cea.13534DOI Listing
January 2020

Pubertal-onset overweight and COPD in men: a cohort study.

ERJ Open Res 2020 Jan 2;6(1). Epub 2020 Mar 2.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1183/23120541.00326-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049738PMC
January 2020

Reply.

Arthritis Rheumatol 2019 12 16;71(12):2132. Epub 2019 Oct 16.

University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/art.41087DOI Listing
December 2019

Liver-derived IGF-I is not required for protection against osteoarthritis in male mice.

Am J Physiol Endocrinol Metab 2019 12 22;317(6):E1150-E1157. Epub 2019 Oct 22.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00330.2019DOI Listing
December 2019

The gut microbiota is a major regulator of androgen metabolism in intestinal contents.

Am J Physiol Endocrinol Metab 2019 12 5;317(6):E1182-E1192. Epub 2019 Nov 5.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1152/ajpendo.00338.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962501PMC
December 2019

Pubertal timing and adult fracture risk in men: A population-based cohort study.

PLoS Med 2019 12 2;16(12):e1002986. Epub 2019 Dec 2.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1002986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886748PMC
December 2019

Estrogen biosynthesis in cultured skeletal muscle cells (L6) induced by amino acids.

Genes Nutr 2019 12;14:29. Epub 2019 Nov 12.

1Surgical Metabolic Research Lab, Department of Surgery, Institute of clinical sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s12263-019-0652-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849273PMC
November 2019

Osteoblast-derived NOTUM reduces cortical bone mass in mice and the locus is associated with bone mineral density in humans.

FASEB J 2019 10 15;33(10):11163-11179. Epub 2019 Jul 15.

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Centre for Bone and Arthritis Research at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1096/fj.201900707RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766646PMC
October 2019

Effects of the selective GPER1 agonist G1 on bone growth.

Endocr Connect 2019 Sep;8(9):1302-1309

Department of Women's and Children's Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden.

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http://dx.doi.org/10.1530/EC-19-0274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765336PMC
September 2019

Secular Trends in Pubertal Growth Acceleration in Swedish Boys Born From 1947 to 1996.

JAMA Pediatr 2019 Jul 22. Epub 2019 Jul 22.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1001/jamapediatrics.2019.2315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647355PMC
July 2019

BMI Change During Puberty Is an Important Determinant of Adult Type 2 Diabetes Risk in Men.

J Clin Endocrinol Metab 2019 05;104(5):1823-1832

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/jc.2018-01339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456008PMC
May 2019

Childhood Body Mass Index Is Associated with Risk of Adult Colon Cancer in Men: An Association Modulated by Pubertal Change in Body Mass Index.

Cancer Epidemiol Biomarkers Prev 2019 05 6;28(5):974-979. Epub 2019 Mar 6.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-1077DOI Listing
May 2019

Interactions Between the Gravitostat and the Fibroblast Growth Factor System for the Regulation of Body Weight.

Endocrinology 2019 05;160(5):1057-1064

Centre for Bone and Arthritis Research, Department of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/en.2018-01002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541891PMC
May 2019

Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment.

FASEB J 2019 04 18;33(4):4962-4974. Epub 2019 Jan 18.

Department of Women's and Children's Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden.

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https://www.fasebj.org/doi/10.1096/fj.201801741R
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http://dx.doi.org/10.1096/fj.201801741RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988867PMC
April 2019

The fracture predictive ability of a musculoskeletal composite score in old men - data from the MrOs Sweden study.

BMC Geriatr 2019 03 22;19(1):90. Epub 2019 Mar 22.

Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences and Orthopedics, Lund University, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1186/s12877-019-1106-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431016PMC
March 2019

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men.

J Clin Endocrinol Metab 2019 02;104(2):433-442

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/jc.2018-00934DOI Listing
February 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 02;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Androgen receptor SUMOylation regulates bone mass in male mice.

Mol Cell Endocrinol 2019 01 24;479:117-122. Epub 2018 Sep 24.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2018.09.008DOI Listing
January 2019

The androgen receptor is required for maintenance of bone mass in adult male mice.

Mol Cell Endocrinol 2019 01 9;479:159-169. Epub 2018 Oct 9.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2018.10.008DOI Listing
January 2019

Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts.

Am J Pathol 2018 12 28;188(12):2890-2901. Epub 2018 Sep 28.

Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland; Turku Center for Disease Modeling, University of Turku, Turku, Finland; Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.07.029DOI Listing
December 2018

Childhood BMI is inversely associated with pubertal timing in normal-weight but not overweight boys.

Am J Clin Nutr 2018 12;108(6):1259-1263

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine.

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https://academic.oup.com/ajcn/advance-article/doi/10.1093/aj
Publisher Site
http://dx.doi.org/10.1093/ajcn/nqy201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300589PMC
December 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Estrogens and selective estrogen receptor modulators differentially antagonize Runx2 in ST2 mesenchymal progenitor cells.

J Steroid Biochem Mol Biol 2018 10 8;183:10-17. Epub 2018 May 8.

Center of Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA; Departments of Biochemistry and Molecular Medicine, Los Angeles, CA, USA; Institute for Genetic Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA; Departments of Orthopedic Surgery, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2018.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128776PMC
October 2018

Clinically relevant doses of vitamin A decrease cortical bone mass in mice

J Endocrinol 2018 10 31;239(3):389-402. Epub 2018 Oct 31.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215918PMC
http://dx.doi.org/10.1530/JOE-18-0316DOI Listing
October 2018

High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden Study.

J Bone Miner Res 2018 09 11;33(9):1560-1567. Epub 2018 May 11.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3443DOI Listing
September 2018

Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer.

Endocr Relat Cancer 2018 09 17;25(9):807-819. Epub 2018 May 17.

Research Centre for Integrative Physiology and PharmacologyInstitute of Biomedicine, University of Turku, Turku, Finland

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http://dx.doi.org/10.1530/ERC-18-0148DOI Listing
September 2018

Serum DHEA and Its Sulfate Are Associated With Incident Fall Risk in Older Men: The MrOS Sweden Study.

J Bone Miner Res 2018 07 10;33(7):1227-1232. Epub 2018 Apr 10.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3418DOI Listing
July 2018

Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.

J Endocrinol 2018 07 2;238(1):13-23. Epub 2018 May 2.

Centre for Bone and Arthritis ResearchInstitute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1530/JOE-18-0153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987170PMC
July 2018

The Gravitostat Regulates Fat Mass in Obese Male Mice While Leptin Regulates Fat Mass in Lean Male Mice.

Endocrinology 2018 07;159(7):2676-2682

Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1210/en.2018-00307DOI Listing
July 2018

WNT16 overexpression partly protects against glucocorticoid-induced bone loss.

Am J Physiol Endocrinol Metab 2018 06 6;314(6):E597-E604. Epub 2018 Feb 6.

Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg , Gothenburg , Sweden.

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http://dx.doi.org/10.1152/ajpendo.00292.2017DOI Listing
June 2018

Translational studies provide insights for the etiology and treatment of cortical bone osteoporosis.

Best Pract Res Clin Endocrinol Metab 2018 06 27;32(3):329-340. Epub 2018 Feb 27.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2018.02.006DOI Listing
June 2018

Antibiotics with Interleukin-15 Inhibition Reduce Joint Inflammation and Bone Erosions but Not Cartilage Destruction in Staphylococcus aureus-Induced Arthritis.

Infect Immun 2018 05 23;86(5). Epub 2018 Apr 23.

Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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http://dx.doi.org/10.1128/IAI.00960-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913847PMC
May 2018

Inducible inactivation: WNT16 regulates cortical bone thickness in adult mice.

J Endocrinol 2018 05 12;237(2):113-122. Epub 2018 Mar 12.

Centre for Bone and Arthritis ResearchDepartment of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden

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http://dx.doi.org/10.1530/JOE-18-0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037PMC
May 2018

Osteomicrobiology: A New Cross-Disciplinary Research Field.

Calcif Tissue Int 2018 04 27;102(4):426-432. Epub 2017 Oct 27.

Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Vita Stråket 11, 413 45, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00223-017-0336-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851705PMC
April 2018

Roles of activating functions 1 and 2 of estrogen receptor α in lymphopoiesis.

J Endocrinol 2018 02 18;236(2):99-109. Epub 2017 Dec 18.

Centre for Bone and Arthritis ResearchDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1530/JOE-17-0372DOI Listing
February 2018

Reply to Lund: Where does the gravitostat fit in?

Proc Natl Acad Sci U S A 2018 02 23;115(7):E1335. Epub 2018 Jan 23.

Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, SE 405 30, Gothenburg, Sweden.

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http://dx.doi.org/10.1073/pnas.1800116115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816225PMC
February 2018

Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer Xenografts.

Am J Pathol 2018 01 7;188(1):216-228. Epub 2017 Nov 7.

Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland; Turku Center for Disease Modeling, Institute of Biomedicine, University of Turku, Turku, Finland; Center for Bone and Arthritis Research, The Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440173053
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http://dx.doi.org/10.1016/j.ajpath.2017.08.036DOI Listing
January 2018

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

Am J Hum Genet 2018 01;102(1):88-102

Department of Internal Medicine, Erasmus MC, 3000 CA Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC, 3000 CA Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC, 3000 CA Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777980PMC
January 2018

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Authors:
Xia Jiang Paul F O'Reilly Hugues Aschard Yi-Hsiang Hsu J Brent Richards Josée Dupuis Erik Ingelsson David Karasik Stefan Pilz Diane Berry Bryan Kestenbaum Jusheng Zheng Jianan Luan Eleni Sofianopoulou Elizabeth A Streeten Demetrius Albanes Pamela L Lutsey Lu Yao Weihong Tang Michael J Econs Henri Wallaschofski Henry Völzke Ang Zhou Chris Power Mark I McCarthy Erin D Michos Eric Boerwinkle Stephanie J Weinstein Neal D Freedman Wen-Yi Huang Natasja M Van Schoor Nathalie van der Velde Lisette C P G M de Groot Anke Enneman L Adrienne Cupples Sarah L Booth Ramachandran S Vasan Ching-Ti Liu Yanhua Zhou Samuli Ripatti Claes Ohlsson Liesbeth Vandenput Mattias Lorentzon Johan G Eriksson M Kyla Shea Denise K Houston Stephen B Kritchevsky Yongmei Liu Kurt K Lohman Luigi Ferrucci Munro Peacock Christian Gieger Marian Beekman Eline Slagboom Joris Deelen Diana van Heemst Marcus E Kleber Winfried März Ian H de Boer Alexis C Wood Jerome I Rotter Stephen S Rich Cassianne Robinson-Cohen Martin den Heijer Marjo-Riitta Jarvelin Alana Cavadino Peter K Joshi James F Wilson Caroline Hayward Lars Lind Karl Michaëlsson Stella Trompet M Carola Zillikens Andre G Uitterlinden Fernando Rivadeneira Linda Broer Lina Zgaga Harry Campbell Evropi Theodoratou Susan M Farrington Maria Timofeeva Malcolm G Dunlop Ana M Valdes Emmi Tikkanen Terho Lehtimäki Leo-Pekka Lyytikäinen Mika Kähönen Olli T Raitakari Vera Mikkilä M Arfan Ikram Naveed Sattar J Wouter Jukema Nicholas J Wareham Claudia Langenberg Nita G Forouhi Thomas E Gundersen Kay-Tee Khaw Adam S Butterworth John Danesh Timothy Spector Thomas J Wang Elina Hyppönen Peter Kraft Douglas P Kiel

Nat Commun 2018 01 17;9(1):260. Epub 2018 Jan 17.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-02662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772647PMC
January 2018

Bone Mass Development from Childhood into Young Adulthood in Patients with Childhood-onset Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 12;23(12):2215-2226

*Department of Pediatrics, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg and Queen Silvia Children's Hospital, Gothenburg, Sweden; †Premier Research LLC, Durham, North Carolina; ‡Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; and §Geriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg and Geriatric Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1097/MIB.0000000000001277DOI Listing
December 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Dihydrotestosterone levels at birth associate positively with higher proportions of circulating immature/naïve CD5 B cells in boys.

Sci Rep 2017 Nov 14;7(1):15503. Epub 2017 Nov 14.

Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41598-017-15836-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686210PMC
November 2017

Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.

Development 2017 09 21;144(18):3264-3277. Epub 2017 Aug 21.

Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen 2200, Denmark

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http://dx.doi.org/10.1242/dev.155473DOI Listing
September 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Authors:
Mariaelisa Graff Robert A Scott Anne E Justice Kristin L Young Mary F Feitosa Llilda Barata Thomas W Winkler Audrey Y Chu Anubha Mahajan David Hadley Luting Xue Tsegaselassie Workalemahu Nancy L Heard-Costa Marcel den Hoed Tarunveer S Ahluwalia Qibin Qi Julius S Ngwa Frida Renström Lydia Quaye John D Eicher James E Hayes Marilyn Cornelis Zoltan Kutalik Elise Lim Jian'an Luan Jennifer E Huffman Weihua Zhang Wei Zhao Paula J Griffin Toomas Haller Shafqat Ahmad Pedro M Marques-Vidal Stephanie Bien Loic Yengo Alexander Teumer Albert Vernon Smith Meena Kumari Marie Neergaard Harder Johanne Marie Justesen Marcus E Kleber Mette Hollensted Kurt Lohman Natalia V Rivera John B Whitfield Jing Hua Zhao Heather M Stringham Leo-Pekka Lyytikäinen Charlotte Huppertz Gonneke Willemsen Wouter J Peyrot Ying Wu Kati Kristiansson Ayse Demirkan Myriam Fornage Maija Hassinen Lawrence F Bielak Gemma Cadby Toshiko Tanaka Reedik Mägi Peter J van der Most Anne U Jackson Jennifer L Bragg-Gresham Veronique Vitart Jonathan Marten Pau Navarro Claire Bellis Dorota Pasko Åsa Johansson Søren Snitker Yu-Ching Cheng Joel Eriksson Unhee Lim Mette Aadahl Linda S Adair Najaf Amin Beverley Balkau Juha Auvinen John Beilby Richard N Bergman Sven Bergmann Alain G Bertoni John Blangero Amélie Bonnefond Lori L Bonnycastle Judith B Borja Søren Brage Fabio Busonero Steve Buyske Harry Campbell Peter S Chines Francis S Collins Tanguy Corre George Davey Smith Graciela E Delgado Nicole Dueker Marcus Dörr Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Jessica D Faul Mao Fu Kristine Færch Christian Gieger Sven Gläser Jian Gong Penny Gordon-Larsen Harald Grallert Tanja B Grammer Niels Grarup Gerard van Grootheest Kennet Harald Nicholas D Hastie Aki S Havulinna Dena Hernandez Lucia Hindorff Lynne J Hocking Oddgeir L Holmens Christina Holzapfel Jouke Jan Hottenga Jie Huang Tao Huang Jennie Hui Cornelia Huth Nina Hutri-Kähönen Alan L James John-Olov Jansson Min A Jhun Markus Juonala Leena Kinnunen Heikki A Koistinen Ivana Kolcic Pirjo Komulainen Johanna Kuusisto Kirsti Kvaløy Mika Kähönen Timo A Lakka Lenore J Launer Benjamin Lehne Cecilia M Lindgren Mattias Lorentzon Robert Luben Michel Marre Yuri Milaneschi Keri L Monda Grant W Montgomery Marleen H M De Moor Antonella Mulas Martina Müller-Nurasyid A W Musk Reija Männikkö Satu Männistö Narisu Narisu Matthias Nauck Jennifer A Nettleton Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Lavinia Paternoster Jeremiah Perez Markus Perola Annette Peters Ulrike Peters Patricia A Peyser Inga Prokopenko Hannu Puolijoki Olli T Raitakari Tuomo Rankinen Laura J Rasmussen-Torvik Rajesh Rawal Paul M Ridker Lynda M Rose Igor Rudan Cinzia Sarti Mark A Sarzynski Kai Savonen William R Scott Serena Sanna Alan R Shuldiner Steve Sidney Günther Silbernagel Blair H Smith Jennifer A Smith Harold Snieder Alena Stančáková Barbara Sternfeld Amy J Swift Tuija Tammelin Sian-Tsung Tan Barbara Thorand Dorothée Thuillier Liesbeth Vandenput Henrik Vestergaard Jana V van Vliet-Ostaptchouk Marie-Claude Vohl Uwe Völker Gérard Waeber Mark Walker Sarah Wild Andrew Wong Alan F Wright M Carola Zillikens Niha Zubair Christopher A Haiman Loic Lemarchand Ulf Gyllensten Claes Ohlsson Albert Hofman Fernando Rivadeneira André G Uitterlinden Louis Pérusse James F Wilson Caroline Hayward Ozren Polasek Francesco Cucca Kristian Hveem Catharina A Hartman Anke Tönjes Stefania Bandinelli Lyle J Palmer Sharon L R Kardia Rainer Rauramaa Thorkild I A Sørensen Jaakko Tuomilehto Veikko Salomaa Brenda W J H Penninx Eco J C de Geus Dorret I Boomsma Terho Lehtimäki Massimo Mangino Markku Laakso Claude Bouchard Nicholas G Martin Diana Kuh Yongmei Liu Allan Linneberg Winfried März Konstantin Strauch Mika Kivimäki Tamara B Harris Vilmundur Gudnason Henry Völzke Lu Qi Marjo-Riitta Järvelin John C Chambers Jaspal S Kooner Philippe Froguel Charles Kooperberg Peter Vollenweider Göran Hallmans Torben Hansen Oluf Pedersen Andres Metspalu Nicholas J Wareham Claudia Langenberg David R Weir David J Porteous Eric Boerwinkle Daniel I Chasman Gonçalo R Abecasis Inês Barroso Mark I McCarthy Timothy M Frayling Jeffrey R O'Connell Cornelia M van Duijn Michael Boehnke Iris M Heid Karen L Mohlke David P Strachan Caroline S Fox Ching-Ti Liu Joel N Hirschhorn Robert J Klein Andrew D Johnson Ingrid B Borecki Paul W Franks Kari E North L Adrienne Cupples Ruth J F Loos Tuomas O Kilpeläinen

PLoS Genet 2017 Aug 23;13(8):e1006972. Epub 2017 Aug 23.

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http://dx.doi.org/10.1371/journal.pgen.1006972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567921PMC
August 2017

Regulation of bone mass by the gut microbiota is dependent on NOD1 and NOD2 signaling.

Cell Immunol 2017 Jul 19;317:55-58. Epub 2017 May 19.

Centre for Bone and Arthritis Research, Institute of Medicin, Sahlgrenska Academy at University of Gothenburg, SE-413 45 Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2017.05.003DOI Listing
July 2017

BMI increase through puberty and adolescence is associated with risk of adult stroke.

Neurology 2017 Jul 28;89(4):363-369. Epub 2017 Jun 28.

From the Centre for Bone and Arthritis Research, Institute of Medicine (C.O., M.B., J.M.K.), Bioinformatics Core Facility (A.S.), Institute of Biomedicine (C.J.), and Department of Molecular and Clinical Medicine (A.R.), the Sahlgrenska Academy at University of Gothenburg, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000004158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574671PMC
July 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Response to Letter: "Cortical Bone Area Predicts Incident Fractures Independently of Areal Bone Mineral Density in Older Men".

J Clin Endocrinol Metab 2017 05;102(5):1782

Center for Bone Research at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, Sweden.

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http://dx.doi.org/10.1210/jc.2017-00536DOI Listing
May 2017