Publications by authors named "Claes B Wollheim"

106Publications

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells.

Diabetologia 2020 12 22;63(12):2628-2640. Epub 2020 Sep 22.

Nestlé Institute of Health Sciences, Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.

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December 2020

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells.

Diabetes 2020 06 20;69(6):1193-1205. Epub 2020 Mar 20.

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden

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June 2020

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells.

Mol Cell Endocrinol 2018 09 8;472:10-17. Epub 2018 Jun 8.

Lund University Diabetes Center, Malmoe, Lund University, Sweden; Department of Cell Physiology and Metabolism, University Medical Center. Geneva, Switzerland.

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September 2018

Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.

Diabetes 2018 03 11;67(3):372-384. Epub 2017 Dec 11.

Unit of Molecular Metabolism, Department of Clinical Sciences, Lund University Diabetes Centre, Clinical Research Centre, Skåne University Hospital, Malmö, Sweden

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March 2018

Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production.

Mol Cell Endocrinol 2018 02 18;461:205-214. Epub 2017 Sep 18.

Lund University Diabetes Centre, Jan Waldenströms Gata 35, SE-20502 Malmö, Sweden; Department of Neuroscience and Physiology, University of Gothenburg, Medicinaregatan 11, SE-41390 Göteborg, Sweden. Electronic address:

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February 2018

Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes.

Exp Mol Med 2017 02 3;49(2):e291. Epub 2017 Feb 3.

Department of Physiology, Institute of Lifestyle Medicine, Yonsei University Wonju College of Medicine, Gangwon-Do, Republic of Korea.

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February 2017

Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?

Int J Biochem Cell Biol 2017 07 27;88:220-225. Epub 2017 Jan 27.

Department of Cell Physiology and Metabolism, University of Geneva Medical Center, 1 rue Michel-Servet, 1206 Geneva, Switzerland; Faculty Diabetes Center, University of Geneva Medical Center, 1 rue Michel-Servet, 1206 Geneva, Switzerland. Electronic address:

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July 2017

Physiology: Microbial signals to the brain control weight.

Nature 2016 06;534(7606):185-7

Department of Cell Physiology and Metabolism, Centre Médical Universitaire, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.

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June 2016

Is zinc an intra-islet regulator of glucagon secretion?

Diabetol Int 2016 Jun 27;7(2):106-110. Epub 2016 Feb 27.

2Department of Cell Physiology and Metabolism, University Medical Centre, rue Michel-Servet 1, 1211 Geneva 4, Switzerland.

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June 2016

Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function.

J Biol Chem 2016 Mar 20;291(12):6146-57. Epub 2016 Jan 20.

From the Division of Gastroenterology, Departments of Medicine, Pathology & Immunology, and Developmental Biology, Washington University, St. Louis, Missouri 63110,

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March 2016