Publications by authors named "Ciro Zanca"

29Publications

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling.

Cell Metab 2019 09 11;30(3):525-538.e8. Epub 2019 Jul 11.

Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pathology, UCSD School of Medicine, La Jolla, CA 92093, USA; Moores Cancer Center, UCSD School of Medicine, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742496PMC
September 2019

Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.

Cancer Cell 2019 03 28;35(3):504-518.e7. Epub 2019 Feb 28.

Ludwig Institute for Cancer Research, San Diego Branch, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0660, USA; Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA; Department of Pathology, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424615PMC
March 2019

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Cancer Cell 2018 07;34(1):163-177.e7

Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424337PMC
July 2018

Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts.

J Vis Exp 2018 04 26(134). Epub 2018 Apr 26.

Ludwig Institute for Cancer Research; Moores Cancer Center, School of Medicine, University of California, San Diego; Department of Medicine, School of Medicine, University of California, San Diego.

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http://dx.doi.org/10.3791/57448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100979PMC
April 2018

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.

Cancer Cell 2016 Nov 13;30(5):683-693. Epub 2016 Oct 13.

Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, CA 92093, USA; Department of Pathology, UCSD School of Medicine, La Jolla, CA 92093, USA; Moores Cancer Center, UCSD School of Medicine, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479636PMC
November 2016

Epidermal growth factor receptor targeting and challenges in glioblastoma.

Neuro Oncol 2016 07 10;18(7):914-8. Epub 2016 Jan 10.

Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, California (A.H.T., C.Z., F.F.); Moores Cancer Center, University of California at San Diego, La Jolla, California (F.F.); Department of Pathology, University of California at San Diego, La Jolla, California (F.F.).

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http://dx.doi.org/10.1093/neuonc/nov319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896544PMC
July 2016

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.

Mol Cell 2015 Oct 8;60(2):307-18. Epub 2015 Oct 8.

Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA; Department of Pathology, UCSD School of Medicine, La Jolla, CA 92093, USA; Moores Cancer Center, UCSD School of Medicine, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609298PMC
October 2015

Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.

J Cell Physiol 2014 Oct;229(10):1359-68

Department of Molecular Medicine and Medical Biotechnology, "Federico II" University of Naples, Naples, Italy; Institute of Endocrinology and Experimental Oncology "G. Salvatore" (IEOS), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.

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http://doi.wiley.com/10.1002/jcp.24569
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http://dx.doi.org/10.1002/jcp.24569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310550PMC
October 2014

Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.

Cancer Res 2014 Mar 16;74(5):1429-39. Epub 2014 Jan 16.

Authors' Affiliations: Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio; Department of Human and Molecular Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri; and Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947420PMC
March 2014

Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks.

Cancer Biol Med 2013 Dec;10(4):192-205

Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.7497/j.issn.2095-3941.2013.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860350PMC
December 2013

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.

Clin Cancer Res 2013 Oct 12;19(20):5722-32. Epub 2013 Sep 12.

Authors' Affiliations: Laboratory of Molecular Pathology, Ludwig Institute for Cancer Research; Moores Cancer Center; University of California San Diego, La Jolla; Celgene Corporation, San Diego; Department of Neurological Surgery and Brain Tumor Research Center, University of California at San Francisco, San Francisco; California Institute of Technology, Pasadena; Henry Singleton Brain Tumor Program; Jonsson Comprehensive Cancer Center; Department of Neurology, David Geffen UCLA School of Medicine; Department of Molecular and Medical Pharmacology; UCLA Medical Scientist Training Program, University of California, Los Angeles, Los Angeles, California; Celgene Corporation, Summit, New Jersey; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Arthur G. James Cancer Hospital, Columbus, Ohio; Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy; INSERM; Metabolomics Platform, Institut Gustave Roussy, Villejuif; Université Paris Descartes/Sorbonne Paris Cité; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers; and Pôle de Biologie, Hôpital Européen Georges Pompidou, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815450PMC
October 2013

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.

Proc Natl Acad Sci U S A 2012 Oct 24;109(41):16570-5. Epub 2012 Sep 24.

Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Studio di Diagnostica Nucleare (SDN), 80143 Naples, Italy.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1207917109
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http://dx.doi.org/10.1073/pnas.1207917109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478630PMC
October 2012

PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells.

J Cell Physiol 2010 Oct;225(1):63-72

Department of Cellular and Molecular Biology and Pathology, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1002/jcp.22197DOI Listing
October 2010

Contrast agents and renal cell apoptosis.

Eur Heart J 2008 Oct 8;29(20):2569-76. Epub 2008 May 8.

Department of Cellular and Molecular Biology and Pathology, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehn197DOI Listing
October 2008

Selective inhibition of PED protein expression sensitizes B-cell chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis.

Int J Cancer 2007 Mar;120(6):1215-22

Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Via Pansini 5, 80131-Naples, Italy.

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http://dx.doi.org/10.1002/ijc.22495DOI Listing
March 2007

PED mediates AKT-dependent chemoresistance in human breast cancer cells.

Cancer Res 2005 Aug;65(15):6668-75

Department of Cellular and Molecular Biology, Federico II University of Naples, Naples.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4009DOI Listing
August 2005