Publications by authors named "Ciro Leonardo Pierri"

41Publications

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers.

Biomolecules 2020 Dec 30;11(1). Epub 2020 Dec 30.

Department of Biosciences, Biotechnologies, Biopharmaceutics, University "Aldo Moro" of Bari, Via E. Orabona, 4, 70125 Bari, Italy.

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December 2020

Targeting GMC Oxidoreductase with High Affinity Small Molecules for Reducing Patulin Production.

Biology (Basel) 2020 Dec 31;10(1). Epub 2020 Dec 31.

Laboratory of Biochemistry, Molecular and Structural Biology, Department of Biosciences, Biotechnologies, Biopharmaceutics, University of Bari, Via E. Orabona, 4, 70125 Bari, Italy.

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December 2020

Targeting mitochondrial metabolite transporters in Penicillium expansum for reducing patulin production.

Plant Physiol Biochem 2021 Jan 28;158:158-181. Epub 2020 Jul 28.

Laboratory of Biochemistry, Molecular and Structural Biology, Department of Biosciences, Biotechnologies, Biopharmaceutics, University of Bari, Via E. Orabona, 4, 70125, Bari, Italy; BROWSer S.r.l. (https://browser-bioinf.com/) c/o, Department of Biosciences, Biotechnologies, Biopharmaceutics, University "Aldo Moro" of Bari, Via E. Orabona, 4, 70126, Bari, Italy. Electronic address:

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January 2021

Sweet as honey, bitter as bile: Mitochondriotoxic peptides and other therapeutic proteins isolated from animal tissues, for dealing with mitochondrial apoptosis.

Toxicology 2021 01 7;447:152612. Epub 2020 Nov 7.

Laboratory of Biochemistry, Molecular and Structural Biology, Department of Biosciences, Biotechnologies, Biopharmaceutics, University of Bari, Via E. Orabona, 4, 70125, Bari, Italy; BROWSer S.r.l. (https://browser-bioinf.com/) c/o Department of Biosciences, Biotechnologies, Biopharmaceutics, University "Aldo Moro" of Bari, Via E. Orabona, 4, 70126, Bari, Italy. Electronic address:

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January 2021

SARS-CoV-2 spike protein: flexibility as a new target for fighting infection.

Signal Transduct Target Ther 2020 10 30;5(1):254. Epub 2020 Oct 30.

Laboratory of Biochemistry; Molecular and Structural Biology; Department of Biosciences, Biotechnologies, Biopharmaceutics, University of Bari, Via E. Orabona, 4, 70125, Bari, Italy.

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October 2020

Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies.

Cell Mol Life Sci 2020 Jul 4. Epub 2020 Jul 4.

Laboratory of Biochemistry, Molecular and Structural Biology, Department of Biosciences, Biotechnologies, Biopharmaceutics, University of Bari, Via E. Orabona, 4, 70125, Bari, Italy.

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July 2020

FAD/NADH Dependent Oxidoreductases: From Different Amino Acid Sequences to Similar Protein Shapes for Playing an Ancient Function.

J Clin Med 2019 Dec 2;8(12). Epub 2019 Dec 2.

Laboratory of Biochemistry; Molecular and Structural Biology; Department of Biosciences, Biotechnologies, Biopharmaceutics; University of Bari; Via E. Orabona 4; 70125 Bari, Italy.

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December 2019

Beyond the Big Five: Investigating Myostatin Structure, Polymorphism and Expression in .

Front Genet 2019 7;10:502. Epub 2019 Jun 7.

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", Bari, Italy.

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June 2019

Pathogenic Variants in NUP214 Cause "Plugged" Nuclear Pore Channels and Acute Febrile Encephalopathy.

Am J Hum Genet 2019 07 6;105(1):48-64. Epub 2019 Jun 6.

Pediatric Neurology Unit, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel; Monique and Jacques Roboh Department of Genetic Research, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel.

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July 2019

Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive.

Am J Hum Genet 2019 01 27;104(1):179-185. Epub 2018 Dec 27.

Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA. Electronic address:

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January 2019

Metabolic Routes in Inflammation: The Citrate Pathway and its Potential as Therapeutic Target.

Curr Med Chem 2019 ;26(40):7104-7116

Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari, Bari, Italy.

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February 2020

Biochemical characterization of a new mitochondrial transporter of dephosphocoenzyme A in Drosophila melanogaster.

Biochim Biophys Acta Bioenerg 2017 Feb 9;1858(2):137-146. Epub 2016 Nov 9.

Department of Biosciences, Biotechnologies and Biopharmaceutics, Laboratory of Biochemistry and Molecular Biology, University of Bari, via Orabona 4, 70125 Bari, Italy. Electronic address:

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February 2017

Dataset of the AAC2 conformations in the c-, intermediate- and m-states obtained from free-energy simulations.

Data Brief 2016 Jun 13;7:1355-7. Epub 2016 Apr 13.

Institut für Physiologische Chemie, Schillerstr.44, 80336 München, Germany.

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June 2016

Molecular modeling of antibodies for the treatment of TNFα-related immunological diseases.

Pharmacol Res Perspect 2016 Feb 15;4(1):e00197. Epub 2016 Jan 15.

Department of Pharmacy - Drug Science University of Bari Bari Italy.

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February 2016

The switching mechanism of the mitochondrial ADP/ATP carrier explored by free-energy landscapes.

Biochim Biophys Acta 2016 Jun 10;1857(6):772-81. Epub 2016 Feb 10.

Institut für Physiologische Chemie, Schillerstr.44, 80336 München, Germany. Electronic address:

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June 2016

Identification of new highly selective inhibitors of the human ADP/ATP carriers by molecular docking and in vitro transport assays.

Biochem Pharmacol 2016 Jan 23;100:112-32. Epub 2015 Nov 23.

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125 Bari, Italy. Electronic address:

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January 2016

Sirtuin 3 interacts with Lon protease and regulates its acetylation status.

Mitochondrion 2014 Sep 13;18:76-81. Epub 2014 Aug 13.

Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy.

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September 2014

Distance-dependent hydrophobic-hydrophobic contacts in protein folding simulations.

Phys Chem Chem Phys 2014 Sep;16(35):18907-17

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125, Bari, Italy.

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September 2014

Prediction of high- and low-affinity quinol-analogue-binding sites in the aa3 and bo3 terminal oxidases from Bacillus subtilis and Escherichia coli1.

Biochem J 2014 Jul;461(2):305-14

†Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125 Bari, Italy.

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July 2014

Isolated truncus arteriosus associated with a mutation in the plexin-D1 gene.

Am J Med Genet A 2013 Dec 29;161A(12):3115-20. Epub 2013 Oct 29.

Department of Pediatric Cardiology, Hadassah, Hebrew University Medical Center, Jerusalem, Israel.

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December 2013

Mitochondrial glutamate carriers from Drosophila melanogaster: biochemical, evolutionary and modeling studies.

Biochim Biophys Acta 2013 Oct 11;1827(10):1245-55. Epub 2013 Jul 11.

Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.

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October 2013

Single-nucleotide evolution quantifies the importance of each site along the structure of mitochondrial carriers.

Cell Mol Life Sci 2014 Jan 26;71(2):349-64. Epub 2013 Jun 26.

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125, Bari, Italy.

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January 2014

Characterization of mitochondrial dicarboxylate/tricarboxylate transporters from grape berries.

Planta 2013 Mar 25;237(3):693-703. Epub 2012 Oct 25.

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República-EAN, 2780-157, Oeiras, Portugal.

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March 2013

Isolation and characterization of novel variants of BBI coding genes from the legume Lathyrus sativus.

Plant Physiol Biochem 2012 Aug 12;57:45-53. Epub 2012 May 12.

Institute of Plant Genetics (IGV), National Research Council (CNR), Bari, Italy.

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August 2012

The peroxisomal NAD+ carrier of Arabidopsis thaliana transports coenzyme A and its derivatives.

J Bioenerg Biomembr 2012 Jun 4;44(3):333-40. Epub 2012 May 4.

Department of Biosciences, Biotechnology and Pharmacological Sciences, University of Bari, Via Orabona 4, 70125 Bari, Italy.

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June 2012

Mitochondrial metabolite transport.

Essays Biochem 2010 ;47:37-52

Department of Pharmaco-Biology, Laboratory of Biochemistry and Molecular Biology, University of Bari, 70125 Bari, Italy.

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December 2010

Computational approaches for protein function prediction: a combined strategy from multiple sequence alignment to molecular docking-based virtual screening.

Biochim Biophys Acta 2010 Sep 28;1804(9):1695-712. Epub 2010 Apr 28.

Department of Pharmaco-Biology, Laboratory of Biochemistry and Molecular Biology, University of Bari, Va E. Orabona, 4 - 70125 Bari, Italy.

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September 2010

Structure and function of mitochondrial carriers - role of the transmembrane helix P and G residues in the gating and transport mechanism.

FEBS Lett 2010 May 25;584(9):1931-9. Epub 2009 Oct 25.

Department of Pharmaco-Biology, Laboratory of Biochemistry and Molecular Biology, University of Bari, Bari, Italy.

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May 2010

Lattices for ab initio protein structure prediction.

Proteins 2008 Nov;73(2):351-61

Department of Pharmaco-Biology, University of Bari, Va E. Orabona, Bari, Italy.

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November 2008