Cinzia Rinaldo

Cinzia Rinaldo

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Cinzia Rinaldo

Cinzia Rinaldo

Publications by authors named "Cinzia Rinaldo"

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28Publications

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Extrachromosomal Histone H2B Contributes to the Formation of the Abscission Site for Cell Division.

Cells 2019 Nov 5;8(11). Epub 2019 Nov 5.

Unit of Cellular Networks and Molecular Therapeutic Targets, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.

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http://dx.doi.org/10.3390/cells8111391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912571PMC
November 2019

HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission.

Cells 2019 07 5;8(7). Epub 2019 Jul 5.

Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, 00185 Rome, Italy.

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http://dx.doi.org/10.3390/cells8070684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678495PMC
July 2019

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage.

Oncogenesis 2019 Apr 15;8(5):29. Epub 2019 Apr 15.

Department of Chemistry, Centre for Membrane Interactions and Dynamics (CMIAD), Krebs Institute, University of Sheffield, Brook Hill, Sheffield, S3 7HF, United Kingdom.

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http://www.nature.com/articles/s41389-019-0136-0
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http://dx.doi.org/10.1038/s41389-019-0136-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465242PMC
April 2019

HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis.

Oncogene 2018 06 22;37(26):3562-3574. Epub 2018 Mar 22.

Unit of Cellular Networks and Molecular Therapeutic Targets, Regina Elena National Cancer Institute-IRCCS, Rome, 00144, Italy.

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http://dx.doi.org/10.1038/s41388-018-0191-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021368PMC
June 2018

Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain.

Protein Sci 2018 03 28;27(3):725-737. Epub 2017 Dec 28.

Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, P.le A. Moro 5, 00185, Italy, Rome.

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http://doi.wiley.com/10.1002/pro.3367
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http://dx.doi.org/10.1002/pro.3367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818748PMC
March 2018

Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.

Cell Cycle 2016 ;15(6):812-8

a Istituto di Endocrinologia ed Oncologia Sperimentale del CNR and Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II" , Naples , Italy.

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http://www.tandfonline.com/doi/full/10.1080/15384101.2016.11
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http://dx.doi.org/10.1080/15384101.2016.1146835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845974PMC
December 2016

Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.

Oncotarget 2015 Jul;6(19):17342-53

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR and Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II", 80131, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627312PMC
http://dx.doi.org/10.18632/oncotarget.3944DOI Listing
July 2015

Updates on HIPK2: a resourceful oncosuppressor for clearing cancer.

J Exp Clin Cancer Res 2012 Aug 13;31:63. Epub 2012 Aug 13.

Department of Medical, Oral, and Biotechnological Sciences, University "G, d'Annunzio", Chieti 66013, Italy.

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http://dx.doi.org/10.1186/1756-9966-31-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432601PMC
August 2012

Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility.

J Biol Chem 2011 08 29;286(33):29005-13. Epub 2011 Jun 29.

Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1074/jbc.M111.230854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190708PMC
August 2011

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

Mol Cancer Res 2011 Jan 20;9(1):67-77. Epub 2010 Dec 20.

Department of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I, Viale Regina Elena, 324, 00161, Rome, Italy.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0227DOI Listing
January 2011

HIPK2 regulation by MDM2 determines tumor cell response to the p53-reactivating drugs nutlin-3 and RITA.

Cancer Res 2009 Aug 28;69(15):6241-8. Epub 2009 Jul 28.

Department of Experimental Oncology, Molecular Oncogenesis Laboratory, Regina Elena Cancer Institute, Rome, Italy.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-0337DOI Listing
August 2009

HIPKs: Jack of all trades in basic nuclear activities.

Biochim Biophys Acta 2008 Nov 18;1783(11):2124-9. Epub 2008 Jun 18.

Department of Experimental Oncology, Regina Elena Cancer Institute, 00158 Rome, Italy.

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http://dx.doi.org/10.1016/j.bbamcr.2008.06.006DOI Listing
November 2008

HIPK2: a multitalented partner for transcription factors in DNA damage response and development.

Biochem Cell Biol 2007 Aug;85(4):411-8

Department of Experimental Oncology, Regina Elena Cancer Institute, 00158 Rome, Italy.

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http://dx.doi.org/10.1139/O07-071DOI Listing
August 2007

High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2.

J Clin Invest 2007 Mar 8;117(3):693-702. Epub 2007 Feb 8.

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1172/JCI29852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784001PMC
March 2007

MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

Mol Cell 2007 Mar;25(5):739-50

Department of Experimental Oncology, Regina Elena Cancer Institute, Via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1016/j.molcel.2007.02.008DOI Listing
March 2007

Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis.

Exp Cell Res 2004 Feb;293(2):311-20

Deparment of Experimental Oncology, Molecular Oncogenesis Laboratory, Regina Elena Cancer Institute, via delle Messi d'Oro 156, 00158 Rome, Italy.

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http://dx.doi.org/10.1016/j.yexcr.2003.09.032DOI Listing
February 2004

Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development.

Genetics 2002 Feb;160(2):471-9

Istituto di Genetica e Biofisica Adriano Buzzati-Traverso-CNR, 80125 Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1461995PMC
February 2002