Publications by authors named "Chunxu Qu"

40Publications

Targeting ALK in pediatric RMS does not induce antitumor activity in vivo.

Cancer Chemother Pharmacol 2018 08 31;82(2):251-263. Epub 2018 May 31.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-2794, USA.

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http://dx.doi.org/10.1007/s00280-018-3615-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054567PMC
August 2018

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.

Cancer Res 2017 01 4;77(1):123-133. Epub 2016 Nov 4.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214974PMC
January 2017

c-Fos Repression by Piwi Regulates Drosophila Ovarian Germline Formation and Tissue Morphogenesis.

PLoS Genet 2016 09 13;12(9):e1006281. Epub 2016 Sep 13.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021354PMC
September 2016

SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.

Mol Cell 2016 04;62(2):207-221

Department of Molecular Biology, Science III, Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, 1211 Geneva 4, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765160022
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http://dx.doi.org/10.1016/j.molcel.2016.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890606PMC
April 2016

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.

Proc Natl Acad Sci U S A 2015 Dec 23;112(49):15172-7. Epub 2015 Nov 23.

Growth Factor Group, Cancer Research UK, Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1422015112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679044PMC
December 2015

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Cell Stem Cell 2015 Jul;17(1):101-15

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547539PMC
July 2015

The role of histone demethylase KDM4B in Myc signaling in neuroblastoma.

J Natl Cancer Inst 2015 Jun 29;107(6):djv080. Epub 2015 Apr 29.

Department of Surgery (JY, AMA, DH, PHC, CLM, AMD) and Department of Bioinformatics (CQ), St. Jude Children's Research Hospital, Memphis, TN; Yale Cardiovascular Research Center, Yale School of Medicine, New Haven, CT (YW); Department of Oncology, University College London Cancer Institute, London, UK (ACN); Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX (JMS); Division of Biomedical Research, Foundation of Research and Technology-Hellas, Institute of Molecular Biology and Biotechnology, Ioannina, Greece (TF); Laboratory of Biological Chemistry, Medical School, University of Ioannina, Ioannina, Greece (TF); Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands (JK, RV); Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan (HO); Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK (ALH).

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http://dx.doi.org/10.1093/jnci/djv080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555638PMC
June 2015

Development and characterization of a human orthotopic neuroblastoma xenograft.

Dev Biol 2015 Nov 9;407(2):344-55. Epub 2015 Apr 9.

Department of Developmental Neurobiology, St. Jude Children׳s Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00121606150006
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http://dx.doi.org/10.1016/j.ydbio.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995597PMC
November 2015

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Nucleic Acids Res 2014 Oct 23;42(18):11363-82. Epub 2014 Sep 23.

Department of Biochemistry, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1093/nar/gku827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191404PMC
October 2014

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

Cancer Res 2013 Oct 22;73(20):6219-29. Epub 2013 Aug 22.

Authors' Affiliations: Departments of Developmental Neurobiology, Computational Biology, Biostatistics, Oncology, and Pathology, St. Jude Children's Research Hospital; Interdisciplinary Biomedical Science Program, University of Tennessee Health Sciences Center, Memphis, Tennessee; Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Australia; Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, London, United Kingdom; and Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800209PMC
October 2013

Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice.

PLoS One 2012 21;7(3):e33693. Epub 2012 Mar 21.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033693PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312333PMC
August 2012

A mouse model of the most aggressive subgroup of human medulloblastoma.

Cancer Cell 2012 Feb;21(2):168-80

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285412PMC
February 2012

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Cancer Res 2010 Jul 1;70(13):5618-27. Epub 2010 Jun 1.

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896438PMC
July 2010

EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice.

Mol Cell Biol 2007 Nov 17;27(22):7918-34. Epub 2007 Sep 17.

Department of Developmental Neurobiology, Hartwell Center, St. Jude Children's Research Hospital, 332 N. Lauderdale St., Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1128/MCB.00099-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169157PMC
November 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome.

Nat Genet 2007 Mar 4;39(3):311-8. Epub 2007 Feb 4.

Ludwig Institute for Cancer Research, University of California San Diego (UCSD) School of Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653 USA.

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http://dx.doi.org/10.1038/ng1966DOI Listing
March 2007

Enhanced local symmetry interactions globally stabilize a mutant virus capsid that maintains infectivity and capsid dynamics.

J Virol 2006 Apr;80(7):3582-91

Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/JVI.80.7.3582-3591.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440388PMC
April 2006

A high-resolution map of active promoters in the human genome.

Nature 2005 Aug 29;436(7052):876-80. Epub 2005 Jun 29.

Ludwig Institute for Cancer Research, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653, USA.

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http://dx.doi.org/10.1038/nature03877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895599PMC
August 2005

Direct isolation and identification of promoters in the human genome.

Genome Res 2005 Jun 17;15(6):830-9. Epub 2005 May 17.

Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1101/gr.3430605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142473PMC
June 2005

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells.

Proc Natl Acad Sci U S A 2003 Jul 13;100(14):8164-9. Epub 2003 Jun 13.

Ludwig Institute for Cancer Research, University of California at San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0653, USA.

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http://dx.doi.org/10.1073/pnas.1332764100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166200PMC
July 2003

Pseudo-atomic models of swollen CCMV from cryo-electron microscopy data.

J Struct Biol 2003 Jun;142(3):356-63

Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/s1047-8477(03)00028-5DOI Listing
June 2003