Chunxiu Hu

Chunxiu Hu

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Chunxiu Hu

Publications by authors named "Chunxiu Hu"

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Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints

Am J Physiol Endocrinol Metab 2019 06 18. Epub 2019 Jun 18.

Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital Tuebingen, Tuebingen. Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tuebingen, Tuebingen, Germany. German Center for Diabetes Research (DZD), Germany.

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http://dx.doi.org/10.1152/ajpendo.00088.2019DOI Listing
June 2019

Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.

J Proteome Res 2019 Mar 9;18(3):960-969. Epub 2019 Jan 9.

CAS Key Laboratory of Separation Science for Analytical Chemistry , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00663
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http://dx.doi.org/10.1021/acs.jproteome.8b00663DOI Listing
March 2019

Study on the Nonlinear Conductivity of SiC/ZnO/Epoxy Resin Micro- and Nanocomposite Materials.

Materials (Basel) 2019 Mar 5;12(5). Epub 2019 Mar 5.

Key Laboratory of Engineering Dielectrics and Its Application, Ministry of Education, Harbin University of Science and Technology, Harbin 150080, China.

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http://dx.doi.org/10.3390/ma12050761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427385PMC
March 2019

ORP4L Extracts and Presents PIP from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells.

Cell Rep 2019 Feb;26(8):2166-2177.e9

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biology, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.082DOI Listing
February 2019

Breast cancer primary tumor ER expression pattern predicts its expression concordance in matched synchronous lymph node metastases.

BMC Cancer 2018 Dec 27;18(1):1290. Epub 2018 Dec 27.

Department of Radiation Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Jiefang Road 88, Hangzhou, 310009, People's Republic of China.

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http://dx.doi.org/10.1186/s12885-018-5217-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307150PMC
December 2018

Activation of choline kinase drives aberrant choline metabolism in esophageal squamous cell carcinomas.

J Pharm Biomed Anal 2018 Jun 31;155:148-156. Epub 2018 Mar 31.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.03.062DOI Listing
June 2018

Comprehensive Strategy to Construct In-House Database for Accurate and Batch Identification of Small Molecular Metabolites.

Anal Chem 2018 06 8;90(12):7635-7643. Epub 2018 Jun 8.

CAS Key Laboratory of Separation Science for Analytical Chemistry , Dalian Institute of Chemical Physics, Chinese Academy of Science , Dalian 116023 , China.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b01482
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http://dx.doi.org/10.1021/acs.analchem.8b01482DOI Listing
June 2018

Development of a High Coverage Pseudotargeted Lipidomics Method Based on Ultra-High Performance Liquid Chromatography-Mass Spectrometry.

Anal Chem 2018 06 8;90(12):7608-7616. Epub 2018 Jun 8.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics , Chinese Academy of Sciences , Dalian , Liaoning , 116023 , China.

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http://dx.doi.org/10.1021/acs.analchem.8b01331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242181PMC
June 2018

A High-Fat Diet Rich in Saturated and Mono-Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats.

Mol Nutr Food Res 2018 03 28;62(6):e1700599. Epub 2018 Feb 28.

Department of Endocrinology, Shandong Provincial Hospital affiliated to Shandong University, Ji-nan, China.

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http://dx.doi.org/10.1002/mnfr.201700599DOI Listing
March 2018

Metabolic changes in primary, secondary, and lipid metabolism in tobacco leaf in response to topping.

Anal Bioanal Chem 2018 Jan 19;410(3):839-851. Epub 2017 Sep 19.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning, 116023, China.

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http://dx.doi.org/10.1007/s00216-017-0596-zDOI Listing
January 2018

Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma.

Clin Cancer Res 2018 01 30;24(2):474-485. Epub 2017 Oct 30.

Scientific Research Center for Translational Medicine, Department of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-1707DOI Listing
January 2018

A Computational Method of Defining Potential Biomarkers based on Differential Sub-Networks.

Sci Rep 2017 10 30;7(1):14339. Epub 2017 Oct 30.

School of Computer Science & Technology, Dalian University of Technology, 116024, Dalian, China.

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http://dx.doi.org/10.1038/s41598-017-14682-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662748PMC
October 2017

Plasma metabolomics profiling of maintenance hemodialysis based on capillary electrophoresis - time of flight mass spectrometry.

Sci Rep 2017 08 15;7(1):8150. Epub 2017 Aug 15.

CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, 116023, China.

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http://dx.doi.org/10.1038/s41598-017-08327-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557835PMC
August 2017

Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection.

Sci Rep 2017 08 22;7(1):9110. Epub 2017 Aug 22.

Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Haihe Clinical College of Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.1038/s41598-017-09536-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567209PMC
August 2017

Plasma lipidomics reveals potential lipid markers of major depressive disorder.

Anal Bioanal Chem 2016 Sep 25;408(23):6497-507. Epub 2016 Jul 25.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning, 116023, China.

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http://dx.doi.org/10.1007/s00216-016-9768-5DOI Listing
September 2016

The development of plasma pseudotargeted GC-MS metabolic profiling and its application in bladder cancer.

Anal Bioanal Chem 2016 Sep 29;408(24):6741-9. Epub 2016 Jul 29.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning, 116023, China.

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http://dx.doi.org/10.1007/s00216-016-9797-0DOI Listing
September 2016

A New Strategy for Analyzing Time-Series Data Using Dynamic Networks: Identifying Prospective Biomarkers of Hepatocellular Carcinoma.

Sci Rep 2016 08 31;6:32448. Epub 2016 Aug 31.

School of Computer Science &Technology, Dalian University of Technology, 116024 Dalian, China.

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http://dx.doi.org/10.1038/srep32448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006023PMC
August 2016

A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model.

Biol Open 2016 Jul 15;5(7):979-86. Epub 2016 Jul 15.

State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Pukou District, Nanjing 210061, China Collaborative Innovation Center of Genetics and Development, Shanghai 200438, China.

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http://dx.doi.org/10.1242/bio.019802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958281PMC
July 2016

Plasma Lipidomics Investigation of Hemodialysis Effects by Using Liquid Chromatography-Mass Spectrometry.

J Proteome Res 2016 06 19;15(6):1986-94. Epub 2016 May 19.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, China.

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http://dx.doi.org/10.1021/acs.jproteome.6b00170DOI Listing
June 2016

Metabolic Profiling with Gas Chromatography-Mass Spectrometry and Capillary Electrophoresis-Mass Spectrometry Reveals the Carbon-Nitrogen Status of Tobacco Leaves Across Different Planting Areas.

J Proteome Res 2016 Feb 27;15(2):468-76. Epub 2016 Jan 27.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, China.

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http://dx.doi.org/10.1021/acs.jproteome.5b00807DOI Listing
February 2016

Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients.

Sci Rep 2015 Nov 3;5:16101. Epub 2015 Nov 3.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://www.nature.com/articles/srep16101
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http://dx.doi.org/10.1038/srep16101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630653PMC
November 2015

A metabolomics study delineating geographical location-associated primary metabolic changes in the leaves of growing tobacco plants by GC-MS and CE-MS.

Sci Rep 2015 Nov 9;5:16346. Epub 2015 Nov 9.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1038/srep16346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637841PMC
November 2015

Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography-mass spectrometry.

J Proteome Res 2015 May 26;14(5):2322-30. Epub 2015 Mar 26.

†Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.

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http://dx.doi.org/10.1021/acs.jproteome.5b00144DOI Listing
May 2015

On-line stop-flow two-dimensional liquid chromatography-mass spectrometry method for the separation and identification of triterpenoid saponins from ginseng extract.

Anal Bioanal Chem 2015 Jan 20;407(1):331-41. Epub 2014 Nov 20.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.

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http://dx.doi.org/10.1007/s00216-014-8219-4DOI Listing
January 2015

Infertility evaluation via laparoscopy and hysteroscopy after conservative treatment for tubal pregnancy.

Int J Clin Exp Med 2014 15;7(10):3556-61. Epub 2014 Oct 15.

Department of Obstetrics & Gynecology, Affiliated Hospital of The Chinese People's Armed, Police Force Logistics College Tianjin, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238533PMC
November 2014

Lipid profiling reveals different therapeutic effects of metformin and glipizide in patients with type 2 diabetes and coronary artery disease.

Diabetes Care 2014 Oct 10;37(10):2804-12. Epub 2014 Jul 10.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China

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http://dx.doi.org/10.2337/dc14-0090DOI Listing
October 2014

Metabolomics study of hepatocellular carcinoma: discovery and validation of serum potential biomarkers by using capillary electrophoresis-mass spectrometry.

J Proteome Res 2014 Jul 2;13(7):3420-31. Epub 2014 Jun 2.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , 457 Zhongshan Road, Dalian 116023, China.

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http://dx.doi.org/10.1021/pr500390yDOI Listing
July 2014

Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry.

J Pharm Biomed Anal 2014 Feb 9;89:122-9. Epub 2013 Nov 9.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023 Dalian, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2013.10.045DOI Listing
February 2014

Large-scaled human serum sphingolipid profiling by using reversed-phase liquid chromatography coupled with dynamic multiple reaction monitoring of mass spectrometry: method development and application in hepatocellular carcinoma.

J Chromatogr A 2013 Dec 26;1320:103-10. Epub 2013 Oct 26.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1016/j.chroma.2013.10.064DOI Listing
December 2013

A novel strategy to evaluate the quality of traditional Chinese medicine based on the correlation analysis of chemical fingerprint and biological effect.

J Pharm Biomed Anal 2013 Sep 1;83:57-64. Epub 2013 May 1.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1016/j.jpba.2013.04.035DOI Listing
September 2013

Effect of bisphenol A on rat metabolic profiling studied by using capillary electrophoresis time-of-flight mass spectrometry.

Environ Sci Technol 2013 Jul 20;47(13):7457-65. Epub 2013 Jun 20.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

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http://dx.doi.org/10.1021/es400490fDOI Listing
July 2013

Application of plasma lipidomics in studying the response of patients with essential hypertension to antihypertensive drug therapy.

Mol Biosyst 2011 Dec 18;7(12):3271-9. Epub 2011 Oct 18.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, PR China.

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http://dx.doi.org/10.1039/c1mb05342fDOI Listing
December 2011

Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats.

Mol Biosyst 2011 Nov 7;7(11):3094-103. Epub 2011 Sep 7.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.

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http://xlink.rsc.org/?DOI=c1mb05254c
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http://dx.doi.org/10.1039/c1mb05254cDOI Listing
November 2011

[An ultra performance liquid chromatography-time-of-flight-mass spectrometric method for fast analysis of ginsenosides in Panax ginseng root].

Se Pu 2011 Jun;29(6):488-94

Dalian Institute of Chemical Physics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Chinese Academy of Sciences, Dalian 116023, China.

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June 2011

Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice.

PLoS One 2010 Oct 13;5(10):e13318. Epub 2010 Oct 13.

CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013318PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954156PMC
October 2010

Analytical strategies in lipidomics and applications in disease biomarker discovery.

J Chromatogr B Analyt Technol Biomed Life Sci 2009 Sep 5;877(26):2836-46. Epub 2009 Feb 5.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, 457 Zhongshan Road, 116023 Dalian, China.

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http://dx.doi.org/10.1016/j.jchromb.2009.01.038DOI Listing
September 2009

RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model.

J Proteome Res 2008 Nov 8;7(11):4982-91. Epub 2008 Oct 8.

Division of Analytical Biosciences, LACDR, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands.

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http://pubs.acs.org/doi/abs/10.1021/pr800373m
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http://dx.doi.org/10.1021/pr800373mDOI Listing
November 2008