Chung-Wah Siu

Chung-Wah Siu

Chung-Wah Siu

Chung-Wah Siu

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Guideline-Based Critical Care Pathway Improves Long-Term Clinical Outcomes in Patients with Acute Coronary Syndrome.

Sci Rep 2019 Nov 14;9(1):16814. Epub 2019 Nov 14.

Division of Cardiology, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1038/s41598-019-53348-2DOI Listing
November 2019

Expression of Lmna-R225X nonsense mutation results in dilated cardiomyopathy and conduction disorders (DCM-CD) in mice: Impact of exercise training.

Int J Cardiol 2019 Oct 17. Epub 2019 Oct 17.

Cardiology Division, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.09.058DOI Listing
October 2019

Risk of venous thromboembolism in Chinese pregnant women: Hong Kong venous thromboembolism study.

Blood Res 2019 Sep 25;54(3):175-180. Epub 2019 Sep 25.

Cardiology Division, Department of Medicine, the University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.5045/br.2019.54.3.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779932PMC
September 2019

Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study.

Heart Rhythm 2019 Aug 1. Epub 2019 Aug 1.

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong; The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.07.034DOI Listing
August 2019

Prognostic implications of statin intolerance in stable coronary artery disease patients with different levels of high-sensitive troponin.

BMC Cardiovasc Disord 2019 Jul 15;19(1):168. Epub 2019 Jul 15.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1186/s12872-019-1152-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633694PMC
July 2019

Safety and feasibility of a midseptal implantation technique of a leadless pacemaker.

Heart Rhythm 2019 Jun 11;16(6):896-902. Epub 2018 Dec 11.

Cardiology Division, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China; Division of Cardiology, Department of Medicine, University of Hong Kong Shenzhen Hospital, Hong Kong SAR, China; Shenzhen Institutes of Research and Innovation, University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.12.007DOI Listing
June 2019

Trends in statin prescription prevalence, initiation, and dosing: Hong Kong, 2004-2015.

Atherosclerosis 2019 01 10;280:174-182. Epub 2018 Nov 10.

Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.11.015DOI Listing
January 2019

Diagnostic assessment of a deep learning system for detecting atrial fibrillation in pulse waveforms.

Heart 2018 12 31;104(23):1921-1928. Epub 2018 May 31.

Division of Cardiology, Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1136/heartjnl-2018-313147DOI Listing
December 2018

Implantable cardioverter defibrillators in Asian population.

Pacing Clin Electrophysiol 2018 12 24;41(12):1627-1629. Epub 2018 Oct 24.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

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http://doi.wiley.com/10.1111/pace.13525
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http://dx.doi.org/10.1111/pace.13525DOI Listing
December 2018

Empagliflozin Ammeliorates High Glucose Induced-Cardiac Dysfuntion in Human iPSC-Derived Cardiomyocytes.

Sci Rep 2018 10 5;8(1):14872. Epub 2018 Oct 5.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, Hong Kong, China.

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http://www.nature.com/articles/s41598-018-33293-2
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http://dx.doi.org/10.1038/s41598-018-33293-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173708PMC
October 2018

Effectiveness of a nongovernmental organization-led large-scale community atrial fibrillation screening program using the smartphone electrocardiogram: An observational cohort study.

Heart Rhythm 2018 09 8;15(9):1306-1311. Epub 2018 Jun 8.

Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1016/j.hrthm.2018.06.006DOI Listing
September 2018

Sex-Based Differences in Outcomes of Oral Anticoagulation in Patients With Atrial Fibrillation.

J Am Coll Cardiol 2018 07 9;72(3):271-282. Epub 2018 Jul 9.

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183483
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http://dx.doi.org/10.1016/j.jacc.2018.04.066DOI Listing
July 2018

Prognostic implications of early monomorphic and non-monomorphic tachyarrhythmias in patients discharged with acute coronary syndrome.

Heart Rhythm 2018 06 14;15(6):822-829. Epub 2018 Feb 14.

Cardiology Division, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China; Division of Cardiology, Department of Medicine, The University of Hong Kong Shenzhen Hospital, Hong Kong SAR, China; Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.02.016DOI Listing
June 2018

Secular trends and etiologies of venous thromboembolism in Chinese from 2004 to 2016.

Thromb Res 2018 06 21;166:80-85. Epub 2018 Apr 21.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.04.021DOI Listing
June 2018

Impact of provision of time in therapeutic range value on anticoagulation management in atrial fibrillation patients on warfarin.

Postgrad Med J 2018 Apr 19;94(1110):207-211. Epub 2018 Feb 19.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1136/postgradmedj-2017-135457DOI Listing
April 2018

PostOperative ST-segment elevation: not a blocked coronary artery, then what?

Clin Case Rep 2018 04 16;6(4):631-633. Epub 2018 Feb 16.

Division of Cardiology Department of Medicine Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong China.

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http://dx.doi.org/10.1002/ccr3.1116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889249PMC
April 2018

The diagnosis and treatment of venous thromboembolism in asian patients.

Thromb J 2018 18;16. Epub 2018 Jan 18.

1General Clinical Research Center, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., 11217 Taipei, Taiwan.

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http://dx.doi.org/10.1186/s12959-017-0155-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774147PMC
January 2018

Genetically deprived vitamin D exposure predisposes to atrial fibrillation.

Europace 2017 Dec;19(suppl_4):iv25-iv31

Division of Cardiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1093/europace/eux312DOI Listing
December 2017

WATCHMAN device-related thrombus successfully treated with apixaban: A case report.

Medicine (Baltimore) 2017 Nov;96(47):e8693

Cardiology Division, Department of Medicine, The University of Hong Kong.

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http://dx.doi.org/10.1097/MD.0000000000008693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708950PMC
November 2017

Extrinsic pulmonary artery compression mimicking acute pulmonary embolism.

Clin Case Rep 2017 10 17;5(10):1591-1593. Epub 2017 Aug 17.

Division of Cardiology Department of Medicine The University of Hong Kong Hong Kong SAR China.

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http://dx.doi.org/10.1002/ccr3.1099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628242PMC
October 2017

PR interval prolongation in coronary patients or risk equivalent: excess risk of ischemic stroke and vascular pathophysiological insights.

BMC Cardiovasc Disord 2017 08 24;17(1):233. Epub 2017 Aug 24.

Division of Cardiology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Rm 1928, Block K, Hong Kong, China.

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http://dx.doi.org/10.1186/s12872-017-0667-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571504PMC
August 2017

Modeling Treatment Response for Lamin A/C Related Dilated Cardiomyopathy in Human Induced Pluripotent Stem Cells.

J Am Heart Assoc 2017 Jul 28;6(8). Epub 2017 Jul 28.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong, Hong Kong SAR, China

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http://dx.doi.org/10.1161/JAHA.117.005677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586427PMC
July 2017

Diagnostic performance of an automatic blood pressure measurement device, Microlife WatchBP Home A, for atrial fibrillation screening in a real-world primary care setting.

BMJ Open 2017 06 15;7(6):e013685. Epub 2017 Jun 15.

Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1136/bmjopen-2016-013685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577883PMC
June 2017

Screening for Atrial Fibrillation: A Report of the AF-SCREEN International Collaboration.

Circulation 2017 05;135(19):1851-1867

From Heart Research Institute, Charles Perkins Centre, and Concord Hospital Cardiology, University of Sydney, Australia (B.F.); St Georges Hospital, London, UK (J.C.); Johns Hopkins University, Baltimore, MD (H.C.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H., D.C.); Karolinska Institute, Stockholm, Sweden (M.R., J.E., L.F., E.S.); The Shanghai Institute of Hypertension, Ruijin Hospital, Jiaotong University School of Medicine, China (J.W.); Brigham and Womens Hospital, Harvard Medical School, Boston, MA (C.M.A.); The George Institute for Global Health, Sydney, Australia (C.S.A.); Barts Health NHS Trust, London, UK (S.A.); National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, MA (E.J.B.); University of Modena and Reggio Emilia, Italy (G.B.); Klinikum Coburg, Germany (J.B.); Odense University Hospital, Denmark (A.B.); Cardiovascular Research Centre, National Yang-Ming University, Taipei, Taiwan (T.- F.C.); University Hospital, Basel, Switzerland (D.C.); Université François Rabelais, Tours, France (L.F.); University of Birmingham, UK (D.A.F.); Mayo Clinic College of Medicine, Rochester, MN (B.J.G.); University of Toronto, Ontario, Canada (D.J.G., A.V.); Hackensack University Medical Centre, NJ (T.V.G.); Poche Centre, University of Sydney, Australia (K.G.); University of Western Australia, Perth (G.J.H.); Trinity College, Dublin, Ireland (J.H.); Royal Perth Hospital, University of Western Australia (G.S.H.); StopAfib.org, Dallas, TX (M.T.H.); Weill Cornell Medical College, New York (H.K.); Institute of Cardiovascular Sciences, University of Birmingham, UK (P.K.); SWBH and UHB NHS trusts, Birmingham, UK (P.K.); AFNET, Muenster, Germany (P.K.); Lankenau Institute for Medical Research, Wynnewood, OK (P.R.K.); University Hospital of Zurich, Switzerland (D.K.); Chinese University of Hong Kong (V.W.Y.L., B.P.Y.); University of Linköping, Sweden (L.-A.L.); University of Birmingham, UK; Aalborg University, Denmark (G.Y.H.L.); Arrhythmia Alliance, London, UK (T.L.); Charles Perkins Centre, University of Sydney, Australia (N.L.); Cliniques du Sud Luxembourg, Arlon, Belgium (G.H.M.); Institute for Epidemiology Statistics and Informatics, Frankfurt, Germany (C.M.); Edinburgh Napier University, UK (L.N.); Charles Perkins Centre, University of Sydney, Australia (J.O.); Duke University, Durham, NC (J.P.P.); University of Auckland, New Zealand (K.P.); University of Belgrade, Serbia (T.S.P.); KH der Elisabethinen, Ordensklinikum Linz, Austria (H.P.); University of Groningen, University Medical Centre Groningen, The Netherlands (M.R.); University of Alberta, Edmonton, Canada (R.K.S.); University Heart Centre, Hamburg, Germany (R.B.S.); The University of Hong Kong (C.-W.S.); Scripps Translational Science Institute, San Diego, CA (S.S.); Rigshospitalet, The Heart Centre, University of Copenhagen, Denmark (J.H.S.); Ospedale dell'Angelo Venice-Mestre, Venice, Italy (S.T.); Martini Hospital, Groningen, The Netherlands (R.G.T.); Stanford University, CA (M.P.T.); VA Palo Alto Health Care System, CA (M.P.T.); The Department of Medical Research, Bærum Hospital, Rud, Norway (A.T.); Department of General Practice, Academic Medical Center, Amsterdam, The Netherlands (S.B.U.); University of Groningen, University Medical Centre Groningen, The Netherlands (I.C.V.G.); and University of Göttingen, Germany (R.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026693DOI Listing
May 2017

Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.

Stem Cell Reports 2017 03 2;8(3):605-618. Epub 2017 Mar 2.

The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China; Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China; Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, The University of Hong Kong and Guangzhou Institutes of Biomedicine and Health, Hong Kong SAR, China; Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen 518053, China. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355732PMC
March 2017

Letter by Wong et al Regarding Article, "Pregnancy and the Risk of Aortic Dissection or Rupture: A Cohort-Crossover Analysis".

Circulation 2017 03;135(12):e780-e781

From Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026107DOI Listing
March 2017

Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation.

JAMA 2017 03;317(11):1151-1158

Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China8Research Department of Practice and Policy, UCL School of Pharmacy, London, United Kingdom.

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http://dx.doi.org/10.1001/jama.2017.1363DOI Listing
March 2017

Incidence and predictors of sudden arrhythmic death or ventricular tachyarrhythmias after acute coronary syndrome: An asian perspective.

Heart Rhythm 2017 01 15;14(1):81-87. Epub 2016 Sep 15.

Cardiology Division, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China; Shenzhen Institutes of Research and Innovation, University of Hong Kong, Hong Kong SAR, China; Research Centre of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China; Division of Cardiology, Department of Medicine, University of Hong Kong Shenzhen Hospital, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.09.011DOI Listing
January 2017

Head-to-Head Comparison of the AliveCor Heart Monitor and Microlife WatchBP Office AFIB for Atrial Fibrillation Screening in a Primary Care Setting.

Circulation 2017 01;135(1):110-112

From Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (P.-H.C., C.-K.W); and Department of Family Medicine and Primary Healthcare, Hong Kong East Cluster, Hong Kong SAR, China (L.P., Y.-F.W., M.M.-Y.W., D.W.-S.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024439DOI Listing
January 2017

CHADS-VASc Recalibration With an Additional Age Category (50-64 Years) Enhances Stroke Risk Stratification in Chinese Patients With Atrial Fibrillation.

Can J Cardiol 2016 12 13;32(12):1381-1387. Epub 2016 May 13.

Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.05.009DOI Listing
December 2016

Heart failure across Asia: Same healthcare burden but differences in organization of care.

Int J Cardiol 2016 Nov 1;223:163-167. Epub 2016 Aug 1.

National Heart and Lung Institute, Imperial College London (Royal Brompton Hospital), London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.07.256DOI Listing
November 2016

Amelioration of X-Linked Related Autophagy Failure in Danon Disease With DNA Methylation Inhibitor.

Circulation 2016 Nov 27;134(18):1373-1389. Epub 2016 Sep 27.

From Cardiology Division, Department of Medicine (K.-M.N., J.C.Y.H., Y.-K.L., W.-H.L., K.-W.A., Y.-M.L., L.-Y.W., C.-W.S., H.-F.T.) and Department of Psychiatry (A.W.B., S.-W.C., P.C.S., A.C.), Queen Mary Hospital, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine (K.-M.N, C.W.-S., H.-F.T.), Hong Kong-Guangdong Joint Laboratory on Stem Cell and Regenerative Medicine (M.A.E., H.-F.T.), Centre for Genomic Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), State Key Laboratory for Cognitive and Brain Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), and Shenzhen Institutes of Research and Innovation (H.-F.T.), University of Hong Kong, Hong Kong SAR, China; Stem Cell Disease Models, A*STAR Institute of Medical Biology, Singapore (P.Y.M.); MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK (A.W.B.); and Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Guangzhou, China (M.A.E.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019847DOI Listing
November 2016

Quinidine for Brugada syndrome: Panacea or poison?

HeartRhythm Case Rep 2016 Nov 16;2(6):486-490. Epub 2016 Aug 16.

Department of Pediatric and Adolescent Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.hrcr.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419994PMC
November 2016

Time in Therapeutic Range and Percentage of International Normalized Ratio in the Therapeutic Range as a Measure of Quality of Anticoagulation Control in Patients With Atrial Fibrillation.

Can J Cardiol 2016 10 6;32(10):1247.e23-1247.e28. Epub 2015 Nov 6.

Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.10.029DOI Listing
October 2016

Net Clinical Benefit of Dabigatran Over Warfarin in Patients With Atrial Fibrillation Stratified by CHADS-VASc and Time in Therapeutic Range.

Can J Cardiol 2016 10 25;32(10):1247.e15-1247.e21. Epub 2016 Jan 25.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.01.016DOI Listing
October 2016

Letter by Chan and Siu Regarding Article, "Use of Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation Who Have a History of Intracranial Hemorrhage".

Circulation 2016 Sep;134(11):e226-7

From Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022923DOI Listing
September 2016

Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathy.

Stem Cell Res Ther 2016 09 20;7(1):139. Epub 2016 Sep 20.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1186/s13287-016-0401-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029055PMC
September 2016

Clinical Characteristics, Management, and Outcomes of Hospitalized Heart Failure in a Chinese Population-The Hong Kong Heart Failure Registry.

J Card Fail 2016 Aug 18;22(8):600-8. Epub 2016 Mar 18.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2016.03.007DOI Listing
August 2016

Effect of suboptimal anticoagulation treatment with antiplatelet therapy and warfarin on clinical outcomes in patients with nonvalvular atrial fibrillation: A population-wide cohort study.

Heart Rhythm 2016 08 28;13(8):1581-8. Epub 2016 Mar 28.

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong; Research Department of Practice and Policy, UCL School of Pharmacy, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.03.049DOI Listing
August 2016

The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies.

Br J Clin Pharmacol 2016 07 15;82(1):285-300. Epub 2016 Apr 15.

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/bcp.12911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917795PMC
July 2016

Ischaemic stroke in patients with atrial fibrillation with chronic kidney disease undergoing peritoneal dialysis.

Europace 2016 May 25;18(5):665-71. Epub 2015 Oct 25.

Cardiology Division, Department of Medicine, The University of Hong Kong, Hong Kong, China

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http://europace.oxfordjournals.org/content/europace/early/20
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http://dx.doi.org/10.1093/europace/euv289DOI Listing
May 2016

Impact of Antithrombotic Therapy in Atrial Fibrillation on the Presentation of Coronary Artery Disease.

PLoS One 2015 22;10(6):e0131479. Epub 2015 Jun 22.

Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131479PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476741PMC
April 2016

Improvement of surface ECG recording in adult zebrafish reveals that the value of this model exceeds our expectation.

Sci Rep 2016 04 29;6:25073. Epub 2016 Apr 29.

Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1038/srep25073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850402PMC
April 2016

Lysosomal membrane permeabilization is involved in oxidative stress-induced apoptotic cell death in LAMP2-deficient iPSCs-derived cerebral cortical neurons.

Biochem Biophys Rep 2016 Mar 14;5:335-345. Epub 2016 Jan 14.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1016/j.bbrep.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600451PMC
March 2016

Stroke prevention using dabigatran in elderly Chinese patients with atrial fibrillation.

Heart Rhythm 2016 Feb 21;13(2):366-73. Epub 2015 Sep 21.

Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2015.09.015DOI Listing
February 2016

Efficient attenuation of Friedreich's ataxia (FRDA) cardiomyopathy by modulation of iron homeostasis-human induced pluripotent stem cell (hiPSC) as a drug screening platform for FRDA.

Int J Cardiol 2016 Jan 17;203:964-71. Epub 2015 Nov 17.

Neurology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2015.11.101DOI Listing
January 2016

Cardiovascular outcomes associated with use of clarithromycin: population based study.

BMJ 2016 Jan 14;352:h6926. Epub 2016 Jan 14.

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China Research Department of Practice and Policy, UCL School of Pharmacy, London, UK

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http://dx.doi.org/10.1136/bmj.h6926DOI Listing
January 2016

Remodelling of cardiac sympathetic re-innervation with thoracic spinal cord stimulation improves left ventricular function in a porcine model of heart failure.

Europace 2015 Dec 12;17(12):1875-83. Epub 2015 Mar 12.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China Shenzhen Institutes of Research and Innovation, University of Hong Kong, Hong Kong, China

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http://dx.doi.org/10.1093/europace/euu409DOI Listing
December 2015

Slow Heart Rate Predicts New Occurrence of Atrial Fibrillation.

Heart Lung Circ 2015 Nov 30;24(11):1087-93. Epub 2015 May 30.

Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong and Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2015.04.185DOI Listing
November 2015

Subclinical atrial fibrillation and stroke: insights from continuous monitoring by implanted cardiac electronic devices.

Europace 2015 Oct;17 Suppl 2:ii40-6

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China Research Center of Heart, Brain, Hormone and Healthy Ageing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://europace.oxfordjournals.org/content/europace/17/suppl
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http://dx.doi.org/10.1093/europace/euv235DOI Listing
October 2015

Gastrointestinal haemorrhage in atrial fibrillation patients: impact of quality of anticoagulation control.

Eur Heart J Cardiovasc Pharmacother 2015 Oct 11;1(4):265-72. Epub 2015 Aug 11.

Division of Cardiology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China

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http://dx.doi.org/10.1093/ehjcvp/pvv032DOI Listing
October 2015

Clinical Benefit of Warfarin in Dialysis Patients With Atrial Fibrillation.

J Am Coll Cardiol 2015 Sep;66(11):1310-1311

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http://dx.doi.org/10.1016/j.jacc.2015.03.601DOI Listing
September 2015

Benefit of Anticoagulation Therapy in Hyperthyroidism-Related Atrial Fibrillation.

Clin Cardiol 2015 Aug 6;38(8):476-82. Epub 2015 Aug 6.

Division of Cardiology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/clc.22427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711006PMC
August 2015

Angiographic result of T-stenting with small protrusion using drug-eluting stents in the management of ischemic side branch: the ARTEMIS study.

Heart Vessels 2015 Jul 14;30(4):427-31. Epub 2014 Mar 14.

Cardiac Medical Unit, Grantham Hospital, 125 Wong Chuk Hang Road, Hong Kong, China,

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http://dx.doi.org/10.1007/s00380-014-0492-9DOI Listing
July 2015

Continuation of dabigatran therapy in "real-world" practice in Hong Kong.

PLoS One 2014 1;9(8):e101245. Epub 2014 Aug 1.

Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong SAR, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118845PMC
April 2015

One more "C" for CHA2DS2-VASc score?

Authors:
Chung-Wah Siu

J Am Coll Cardiol 2015 Apr;65(15):1602-3

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April 2015

Response to letter regarding article, "Ischemic stroke and intracranial hemorrhage with aspirin, dabigatran, and warfarin: impact of quality of anticoagulation control".

Stroke 2015 Mar 3;46(3):e72. Epub 2015 Feb 3.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1161/STROKEAHA.114.008581DOI Listing
March 2015

Ischemic stroke and intracranial hemorrhage with aspirin, dabigatran, and warfarin: impact of quality of anticoagulation control.

Stroke 2015 Jan 18;46(1):23-30. Epub 2014 Nov 18.

From the Cardiology Division (C.-W.H., M.-H.H., P.-H.C., J.-J.H., E.C., C.-P.L., H.-F.T., C.-W.S.), Endocrinology Division (C.-Y.Y.), and Neurology Division (K.-K.L., K.-H.C.), Department of Medicine, Queen Mary Hospital and Division of Neurosurgery, Department of Surgery, Li Ka Shing Faculty of Medicine (G.K.-K.L.), University of Hong Kong, Hong Kong SAR, China; and University of Birmingham Centre for Cardiovascular Sciences, City Hospital, University Department of Medicine, Birmingham, United Kingdom (G.Y.H.L.).

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.114.
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January 2015

Vascular protective effects of statin-related increase in serum 25-hydroxyvitamin D among high-risk cardiac patients.

J Cardiovasc Med (Hagerstown) 2015 Jan;16(1):51-8

aDivision of Cardiology, Queen Mary Hospital bSchool of Public Health, The University of Hong Kong cDivision of Neurology, Queen Mary Hospital, The University of Hong Kong dDepartment of Medicine, Tung Wah Hospital eDepartment of Clinical Biochemistry Unit, Queen Mary Hospital fDivision of Clinical Pharmacology, Queen Mary Hospital gResearch Center of Heart, Brain, Hormone and Healthy Ageing, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.2459/JCM.0000000000000026DOI Listing
January 2015

Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischemic stroke.

Am J Hypertens 2014 Dec 18;27(12):1486-94. Epub 2014 May 18.

Division of Cardiology, Department of Medicine, University of Hong Kong, Hong Kong, China;

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http://dx.doi.org/10.1093/ajh/hpu070DOI Listing
December 2014

The CHADS2 and CHA2DS2-VASc scores predict adverse vascular function, ischemic stroke and cardiovascular death in high-risk patients without atrial fibrillation: role of incorporating PR prolongation.

Atherosclerosis 2014 Dec 30;237(2):504-13. Epub 2014 Aug 30.

Division of Cardiology, Queen Mary Hospital, The University of Hong Kong, China; Research Center of Heart, Brain, Hormone and Healthy Ageing, University of Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.08.026DOI Listing
December 2014

Refinement of ischemic stroke risk in patients with atrial fibrillation and CHA2 DS2 -VASc score of 1.

Pacing Clin Electrophysiol 2014 Nov 16;37(11):1442-7. Epub 2014 Jul 16.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; Affiliated Hospital of North Sichuan Medical College & Medical Imaging Key Laboratory, Nanchong, Sichuan Province, China.

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http://dx.doi.org/10.1111/pace.12445DOI Listing
November 2014

Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis.

J Neuroimmunol 2014 Nov 19;276(1-2):64-70. Epub 2014 Aug 19.

University Department of Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong; Neuroimmunology and Neuroinflammation Research Laboratory, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong; Research Center of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2014.08.616DOI Listing
November 2014

Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality.

PLoS One 2014 11;9(2):e88283. Epub 2014 Feb 11.

Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China ; Division of Cardiology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088283PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921146PMC
October 2014

Risk of stroke and intracranial hemorrhage in 9727 Chinese with atrial fibrillation in Hong Kong.

Heart Rhythm 2014 Aug 15;11(8):1401-8. Epub 2014 Apr 15.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.hrthm.2014.04.021DOI Listing
August 2014

Pseudo-pre-excitation unraveled down to its core.

Circulation 2014 Aug;130(7):e56-8

From the Cardiac Medical Unit, Grantham Hospital, Hong Kong, China (A.K.-Y.N., K.F.); and the Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China (K.-M.N., H.-F.T., W.-H.L., W.S.C., C.-W.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.008601DOI Listing
August 2014

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate.

J Oncol 2014 7;2014:529468. Epub 2014 Apr 7.

Division of Cardiology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1155/2014/529468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997904PMC
May 2014

Net clinical benefit of warfarin therapy in elderly Chinese patients with atrial fibrillation.

Circ Arrhythm Electrophysiol 2014 Apr 7;7(2):300-6. Epub 2014 Mar 7.

Cardiology Division, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1161/CIRCEP.113.000858DOI Listing
April 2014

Human mesenchymal stem cells upregulate CD1dCD5(+) regulatory B cells in experimental autoimmune encephalomyelitis.

Neuroimmunomodulation 2013 27;20(5):294-303. Epub 2013 Jul 27.

University Department of Medicine, Queen Mary Hospital, Hong Kong, China.

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http://dx.doi.org/10.1159/000351450DOI Listing
March 2014

Future of implantable devices for cardiac rhythm management.

Circulation 2014 Feb;129(7):811-22

Cardiology Division, Department of Medicine, Queen Mary Hospital (C.-P.L., C.-W.S., H.-F.T.) and Research Center of Heart, Brain, Hormone and Healthy Ageing, Li Ka Shing Faculty of Medicine (C.-W.S., H.-F.T.), University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.000312DOI Listing
February 2014

Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes.

Physiol Rep 2014 Feb 25;2(2):e00237. Epub 2014 Feb 25.

Division of Cardiology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China ; Research Centre of Heart, Brain, Hormone & Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/phy2.237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966242PMC
February 2014

Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty.

Circulation 2014 Jan 25;129(1):87-92. Epub 2013 Sep 25.

Division of Cardiology, Department of Medicine (K.-H.Y., A.W., L.P., M.-F.C., H.-Y.L., Y.-M.L., Y.C., C.-W.S., C.-P.L., H.-F.T.) and Department of Surgery (K.-Y.S., D.C., W.-K.A.), University of Hong Kong, Queen Mary Hospital, Hong Kong; Research Centre of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong (K.-H.Y., C.W.-S, H.-F.T.); and Department of Medicine, Affiliated Hospital of North Sichuan Medical College, Sichuan, China (L.P.).

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http://circ.ahajournals.org/content/early/2013/09/25/CIRCULA
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January 2014

Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells.

J Cardiovasc Transl Res 2013 Dec 1;6(6):989-99. Epub 2013 Oct 1.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s12265-013-9510-zDOI Listing
December 2013

Combined paclitaxel-eluting balloon and Genous cobalt-chromium alloy stent utilization in de novo coronary stenoses (PEGASUS).

J Interv Cardiol 2013 Dec 30;26(6):556-60. Epub 2013 Sep 30.

Cardiac Medical Unit, Grantham Hospital, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/joic.12072DOI Listing
December 2013

Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients.

J Geriatr Cardiol 2013 Dec;10(4):330-5

Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 102 Pokfulam Rd., Hong Kong, China.

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http://dx.doi.org/10.3969/j.issn.1671-5411.2013.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888914PMC
December 2013

Prevalence of and associations with reduced exercise capacity in peritoneal dialysis patients.

Am J Kidney Dis 2013 Nov 22;62(5):939-46. Epub 2013 Jul 22.

Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, China; Department of Echocardiography, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chendu, China.

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http://dx.doi.org/10.1053/j.ajkd.2013.05.016DOI Listing
November 2013

Association of subclinical myocardial injury with arterial stiffness in patients with type 2 diabetes mellitus.

Cardiovasc Diabetol 2013 Jun 22;12:94. Epub 2013 Jun 22.

Division of Cardiology, Department of Medicine, the University of Hong Kong, Rm 1929b, Block K, Queen Mary Hospital, China.

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http://dx.doi.org/10.1186/1475-2840-12-94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706358PMC
June 2013