Publications by authors named "Christos Spanos"

29Publications

Integrative vectors for regulated expression of SARS-CoV-2 proteins implicated in RNA metabolism.

Wellcome Open Res 2020 3;5:261. Epub 2020 Nov 3.

Wellcome Centre for Cell Biology, University of Edinburgh, Michael Swann Building, Kings Buildings, Mayfield Road, Edinburgh, EH9 3BF, UK.

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November 2020

The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19 Complex in Meiotic Kinetochore Assembly.

Curr Biol 2020 Oct 31. Epub 2020 Oct 31.

The Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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October 2020

Stress-Induced Translation Inhibition through Rapid Displacement of Scanning Initiation Factors.

Mol Cell 2020 11 13;80(3):470-484.e8. Epub 2020 Oct 13.

Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK. Electronic address:

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November 2020

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment.

J Cell Sci 2020 Aug 25;133(16). Epub 2020 Aug 25.

Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK

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August 2020

The epigenetic regulator ICU11 as an accessory protein of Polycomb Repressive Complex 2.

Proc Natl Acad Sci U S A 2020 07 29;117(28):16660-16666. Epub 2020 Jun 29.

Department of Cell and Developmental Biology, John Innes Centre, Colney Lane, NR47UH Norwich, United Kingdom;

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July 2020

Substrate specificity of the TRAMP nuclear surveillance complexes.

Nat Commun 2020 06 19;11(1):3122. Epub 2020 Jun 19.

Wellcome Center for Cell Biology, University of Edinburgh, Kings Buildings, Swann Building, Edinburgh, EH9 3BF, UK.

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June 2020

-Shaped Copolymer of Polyethylene and Poly(ethylene oxide) under Severe Confinement: Phase State and Dynamics.

Langmuir 2020 Apr 14;36(16):4261-4271. Epub 2020 Apr 14.

Department of Physics, University of Ioannina, 451 10 Ioannina, Greece.

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April 2020

Hap2-Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin.

Genes Dev 2020 02 9;34(3-4):226-238. Epub 2020 Jan 9.

Wellcome Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3BF, United Kingdom.

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February 2020

Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity.

Nat Commun 2019 07 11;10(1):3056. Epub 2019 Jul 11.

Wellcome Centre for Cell Biology, University of Edinburgh, Max Born Crescent, Edinburgh, EH9 3BF, UK.

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July 2019

The molecular basis of monopolin recruitment to the kinetochore.

Chromosoma 2019 09 30;128(3):331-354. Epub 2019 Apr 30.

Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Max Born Crescent, Edinburgh, EH9 3BF, UK.

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September 2019

Reductional Meiosis I Chromosome Segregation Is Established by Coordination of Key Meiotic Kinases.

Dev Cell 2019 05 25;49(4):526-541.e5. Epub 2019 Apr 25.

The Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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May 2019

Defining the RNA interactome by total RNA-associated protein purification.

Mol Syst Biol 2019 04 8;15(4):e8689. Epub 2019 Apr 8.

Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK

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April 2019

In vitro BioID: mapping the CENP-A microenvironment with high temporal and spatial resolution.

Mol Biol Cell 2019 05 20;30(11):1314-1325. Epub 2019 Mar 20.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology and.

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May 2019

Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Cell Rep 2019 02;26(6):1654-1667.e7

Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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February 2019

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.

Elife 2018 05 29;7. Epub 2018 May 29.

Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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May 2018

Genes Important for Meiosis Identified Through a Functional Genomics Screen.

Genetics 2018 02 19;208(2):589-603. Epub 2017 Dec 19.

Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, EH9 3BF, UK

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February 2018

Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5' UTR of tumor-associated mRNAs.

Biochimie 2018 Jan 10;144:169-184. Epub 2017 Nov 10.

Department of Applied Biochemistry, Institute of Biotechnology, TIB 4/3-2, Technische Universität Berlin, Gustav-Meyer-Allee 25, 13355, Berlin, Germany. Electronic address:

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January 2018

14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes.

J Cell Biol 2017 10 31;216(10):3029-3039. Epub 2017 Aug 31.

Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK

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October 2017

Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.

Nat Struct Mol Biol 2017 03 13;24(3):316-324. Epub 2017 Feb 13.

Cryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, Michigan, USA.

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March 2017

Sample Preparation Approaches for iTRAQ Labeling and Quantitative Proteomic Analyses in Systems Biology.

Methods Mol Biol 2016 ;1394:15-24

Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford Surrey, GU2 7XH, UK.

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October 2016

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.

J Cell Biol 2015 Dec 14;211(6):1141-56. Epub 2015 Dec 14.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK

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December 2015