Christos Hatzis, PhD - Yale University

Christos Hatzis

PhD

Yale University

New Haven, CT | United States

Christos Hatzis, PhD - Yale University

Christos Hatzis

PhD

Introduction

Primary Affiliation: Yale University - New Haven, CT , United States

Publications

27Publications

675Reads

-Profile Views

1253PubMed Central Citations

Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes.

PLoS One 2014 16;9(5):e97876. Epub 2014 May 16.

Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097876PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023998PMC
August 2015
19 Reads
58 Citations
3.234 Impact Factor

Statistical measures of transcriptional diversity capture genomic heterogeneity of cancer.

BMC Genomics 2014 Oct 8;15:876. Epub 2014 Oct 8.

Department of Internal Medicine, Yale School of Medicine, Yale Cancer Center, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1186/1471-2164-15-876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197225PMC
October 2014
17 Reads
5 Citations
3.990 Impact Factor

Enhancing reproducibility in cancer drug screening: how do we move forward?

Cancer Res 2014 Aug 11;74(15):4016-23. Epub 2014 Jul 11.

Princess Margaret Cancer Centre, University Health Network; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119520PMC
August 2014
21 Reads
16 Citations
9.330 Impact Factor

Global gene expression changes induced by prolonged cold ischemic stress and preservation method of breast cancer tissue.

Mol Oncol 2014 May 17;8(3):717-27. Epub 2014 Feb 17.

Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048748PMC
May 2014
24 Reads
5 Citations
5.331 Impact Factor

Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers.

Breast Cancer Res Treat 2014 Apr 12;144(3):561-8. Epub 2014 Mar 12.

Yale Cancer Center, Yale School of Medicine, Yale University, 333 Cedar St, PO Box 208032, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1007/s10549-014-2904-zDOI Listing
April 2014
13 Reads
1 Citation
3.940 Impact Factor

Reproducibility of research and preclinical validation: problems and solutions.

Nat Rev Clin Oncol 2013 12 1;10(12):720-4. Epub 2013 Oct 1.

Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520-8032, USA.

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http://dx.doi.org/10.1038/nrclinonc.2013.171DOI Listing
December 2013
10 Reads
18 Citations
14.180 Impact Factor

Identification of serum analytes and metabolites associated with aerobic capacity.

Eur J Appl Physiol 2013 May 27;113(5):1311-20. Epub 2012 Nov 27.

Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA.

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http://link.springer.com/content/pdf/10.1007/s00421-012-2555
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http://link.springer.com/10.1007/s00421-012-2555-x
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http://dx.doi.org/10.1007/s00421-012-2555-xDOI Listing
May 2013
5 Reads
7 Citations
2.190 Impact Factor

Effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers.

J Natl Cancer Inst 2011 Dec 27;103(24):1871-83. Epub 2011 Oct 27.

Nuvera Biosciences, Woburn, MA, USA.

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http://dx.doi.org/10.1093/jnci/djr438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243675PMC
December 2011
12 Reads
29 Citations
12.583 Impact Factor

Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers.

J Clin Oncol 2010 Oct 30;28(28):4316-23. Epub 2010 Aug 30.

Department of Breast Medical Oncology, Unit 1354, The University of Texas M. D. Anderson Cancer Center, PO Box 301439, Houston,TX 77230-1439, USA.

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http://dx.doi.org/10.1200/JCO.2009.27.2419DOI Listing
October 2010
25 Reads
66 Citations
18.430 Impact Factor

Genomic index of sensitivity to endocrine therapy for breast cancer.

J Clin Oncol 2010 Sep 9;28(27):4111-9. Epub 2010 Aug 9.

Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953969PMC
http://dx.doi.org/10.1200/JCO.2010.28.4273DOI Listing
September 2010
18 Reads
97 Citations
18.430 Impact Factor

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.

Authors:
Leming Shi Gregory Campbell Wendell D Jones Fabien Campagne Zhining Wen Stephen J Walker Zhenqiang Su Tzu-Ming Chu Federico M Goodsaid Lajos Pusztai John D Shaughnessy André Oberthuer Russell S Thomas Richard S Paules Mark Fielden Bart Barlogie Weijie Chen Pan Du Matthias Fischer Cesare Furlanello Brandon D Gallas Xijin Ge Dalila B Megherbi W Fraser Symmans May D Wang John Zhang Hans Bitter Benedikt Brors Pierre R Bushel Max Bylesjo Minjun Chen Jie Cheng Jing Cheng Jeff Chou Timothy S Davison Mauro Delorenzi Youping Deng Viswanath Devanarayan David J Dix Joaquin Dopazo Kevin C Dorff Fathi Elloumi Jianqing Fan Shicai Fan Xiaohui Fan Hong Fang Nina Gonzaludo Kenneth R Hess Huixiao Hong Jun Huan Rafael A Irizarry Richard Judson Dilafruz Juraeva Samir Lababidi Christophe G Lambert Li Li Yanen Li Zhen Li Simon M Lin Guozhen Liu Edward K Lobenhofer Jun Luo Wen Luo Matthew N McCall Yuri Nikolsky Gene A Pennello Roger G Perkins Reena Philip Vlad Popovici Nathan D Price Feng Qian Andreas Scherer Tieliu Shi Weiwei Shi Jaeyun Sung Danielle Thierry-Mieg Jean Thierry-Mieg Venkata Thodima Johan Trygg Lakshmi Vishnuvajjala Sue Jane Wang Jianping Wu Yichao Wu Qian Xie Waleed A Yousef Liang Zhang Xuegong Zhang Sheng Zhong Yiming Zhou Sheng Zhu Dhivya Arasappan Wenjun Bao Anne Bergstrom Lucas Frank Berthold Richard J Brennan Andreas Buness Jennifer G Catalano Chang Chang Rong Chen Yiyu Cheng Jian Cui Wendy Czika Francesca Demichelis Xutao Deng Damir Dosymbekov Roland Eils Yang Feng Jennifer Fostel Stephanie Fulmer-Smentek James C Fuscoe Laurent Gatto Weigong Ge Darlene R Goldstein Li Guo Donald N Halbert Jing Han Stephen C Harris Christos Hatzis Damir Herman Jianping Huang Roderick V Jensen Rui Jiang Charles D Johnson Giuseppe Jurman Yvonne Kahlert Sadik A Khuder Matthias Kohl Jianying Li Li Li Menglong Li Quan-Zhen Li Shao Li Zhiguang Li Jie Liu Ying Liu Zhichao Liu Lu Meng Manuel Madera Francisco Martinez-Murillo Ignacio Medina Joseph Meehan Kelci Miclaus Richard A Moffitt David Montaner Piali Mukherjee George J Mulligan Padraic Neville Tatiana Nikolskaya Baitang Ning Grier P Page Joel Parker R Mitchell Parry Xuejun Peng Ron L Peterson John H Phan Brian Quanz Yi Ren Samantha Riccadonna Alan H Roter Frank W Samuelson Martin M Schumacher Joseph D Shambaugh Qiang Shi Richard Shippy Shengzhu Si Aaron Smalter Christos Sotiriou Mat Soukup Frank Staedtler Guido Steiner Todd H Stokes Qinglan Sun Pei-Yi Tan Rong Tang Zivana Tezak Brett Thorn Marina Tsyganova Yaron Turpaz Silvia C Vega Roberto Visintainer Juergen von Frese Charles Wang Eric Wang Junwei Wang Wei Wang Frank Westermann James C Willey Matthew Woods Shujian Wu Nianqing Xiao Joshua Xu Lei Xu Lun Yang Xiao Zeng Jialu Zhang Li Zhang Min Zhang Chen Zhao Raj K Puri Uwe Scherf Weida Tong Russell D Wolfinger

Nat Biotechnol 2010 Aug 30;28(8):827-38. Epub 2010 Jul 30.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.1038/nbt.1665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315840PMC
August 2010
93 Reads
234 Citations
41.514 Impact Factor

Development of candidate genomic markers to select breast cancer patients for dasatinib therapy.

Mol Cancer Ther 2010 May 27;9(5):1120-7. Epub 2010 Apr 27.

Department of Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-1117DOI Listing
May 2010
8 Reads
9 Citations
5.683 Impact Factor

Genomic grade index is associated with response to chemotherapy in patients with breast cancer.

J Clin Oncol 2009 Jul 13;27(19):3185-91. Epub 2009 Apr 13.

DPhil, Departments of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1200/JCO.2008.18.5934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716940PMC
July 2009
2 Reads
47 Citations
18.430 Impact Factor

Analysis and modeling of growing budding yeast populations at the single cell level.

Cytometry A 2009 Feb;75(2):114-20

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan 20126, Italy.

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http://dx.doi.org/10.1002/cyto.a.20689DOI Listing
February 2009
18 Reads
5 Citations
2.930 Impact Factor

Commercialized multigene predictors of clinical outcome for breast cancer.

Oncologist 2008 May;13(5):477-93

Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, New York 12208, USA.

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http://dx.doi.org/10.1634/theoncologist.2007-0248DOI Listing
May 2008
5 Reads
55 Citations
4.870 Impact Factor

CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer.

Mol Cancer Res 2007 Dec;5(12):1285-95

Department of Carcinogenesis, The University of Texas M. D. Anderson Cancer Center, Science Park Research Division, 1808 Park Road 1C, P.O. Box 389, Smithville, TX 78957, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0126DOI Listing
December 2007
17 Reads
10 Citations
4.380 Impact Factor

Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy.

J Clin Oncol 2007 Oct 4;25(28):4414-22. Epub 2007 Sep 4.

Department of Pathology, Unit 85, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.1200/JCO.2007.10.6823DOI Listing
October 2007
153 Reads
228 Citations
18.430 Impact Factor

Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer.

Clin Cancer Res 2007 Jul;13(14):4078-82

Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2600DOI Listing
July 2007
21 Reads
5 Citations
8.722 Impact Factor

Microtubule-associated protein-tau is a bifunctional predictor of endocrine sensitivity and chemotherapy resistance in estrogen receptor-positive breast cancer.

Clin Cancer Res 2007 Apr;13(7):2061-7

Breast Cancer Unit and Translational Research Unit, UPRES03535, Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2078DOI Listing
April 2007
10 Reads
29 Citations
8.722 Impact Factor

Large-scale identification of novel transcripts in the human genome.

Genome Res 2007 Mar 31;17(3):287-92. Epub 2007 Jan 31.

The Ludwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins University Kimmel Cancer Center, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1101/gr.5486607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800919PMC
March 2007
41 Reads
11 Citations
14.630 Impact Factor

Towards understanding of the complex structure of growing yeast populations.

J Biotechnol 2007 Feb 26;128(2):393-402. Epub 2006 Oct 26.

Department of Biotechnology and Biosciences, University of Milano-Biocca, Milan, Italy.

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http://dx.doi.org/10.1016/j.jbiotec.2006.10.012DOI Listing
February 2007
6 Reads
4 Citations
2.871 Impact Factor

Morphologically-structured models of growing budding yeast populations.

J Biotechnol 2006 Jul 3;124(2):420-38. Epub 2006 Mar 3.

Nuvera Biosciences, Woburn, MA 01801, USA.

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http://dx.doi.org/10.1016/j.jbiotec.2006.01.011DOI Listing
July 2006
2 Reads
4 Citations
2.871 Impact Factor

Ambient particulate matter exhibits direct inhibitory effects on oxidative stress enzymes.

Environ Sci Technol 2006 Apr;40(8):2805-11

Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1021/es0518732DOI Listing
April 2006
2 Reads
12 Citations
5.330 Impact Factor