Christopher Toon

Christopher Toon

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Christopher Toon

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NK-cell enteropathy, a potential diagnostic pitfall of intestinal lymphoproliferative disease.

Pathology 2019 04 26;51(3):338-340. Epub 2019 Feb 26.

Sydney Medical School, University of Sydney, NSW, Australia; Tissue Pathology and Diagnostic Oncology, ICPMR, Westmead Hospital, NSW, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025183037
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http://dx.doi.org/10.1016/j.pathol.2018.09.064DOI Listing
April 2019

Patterns of p53 immunoreactivity in non-neoplastic and neoplastic Barrett's mucosa of the oesophagus: in-depth evaluation in endoscopic mucosal resections.

Pathology 2019 Apr 28;51(3):253-260. Epub 2019 Feb 28.

PathWest Laboratory Medicine, Perth, WA, Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1016/j.pathol.2018.12.415DOI Listing
April 2019

The epithelioid BAP1-negative and p16-positive phenotype predicts prolonged survival in pleural mesothelioma.

Histopathology 2018 Feb 29;72(3):509-515. Epub 2017 Nov 29.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia.

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http://dx.doi.org/10.1111/his.13392DOI Listing
February 2018

Neoplasia associated IgG4-related sclerosis: a new disease paradigm in the salivary gland and potential diagnostic pitfall.

Pathology 2017 Dec 1;49(7):796-798. Epub 2017 Nov 1.

Histopath Specialist Pathologists, Macquarie Park, Australia.

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http://dx.doi.org/10.1016/j.pathol.2017.07.009DOI Listing
December 2017

An unusual presentation of eosinophilic angiocentric fibrosis.

J Surg Case Rep 2017 Dec 8;2017(12):rjx234. Epub 2017 Dec 8.

Department of Otolaryngology, Head and neck surgery, Royal Prince Alfred Hospital, Camperdown NSW, Australia.

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http://dx.doi.org/10.1093/jscr/rjx234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723982PMC
December 2017

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 10 27;550(7677):548. Epub 2017 Sep 27.

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http://dx.doi.org/10.1038/nature24026DOI Listing
October 2017

NRASQ61R Mutation-specific Immunohistochemistry is Highly Specific for Either NRASQ61R or KRASQ61R Mutation in Colorectal Carcinoma.

Appl Immunohistochem Mol Morphol 2017 08;25(7):475-480

*Sydney Medical School, University of Sydney, Sydney †Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research ‡Sydney Vital Translational Research Centre §Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards ∥Histopath Pathology, North Ryde, NSW, Australia ¶Auckland UniServices Sequenom Facility, Liggins Institute #IGENZ Ltd., Auckland, New Zealand.

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http://dx.doi.org/10.1097/PAI.0000000000000333DOI Listing
August 2017

Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 03 15;543(7643):65-71. Epub 2017 Feb 15.

University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, 3010, Victoria, Australia.

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http://dx.doi.org/10.1038/nature21063DOI Listing
March 2017

Hypermutation In Pancreatic Cancer.

Gastroenterology 2017 01 15;152(1):68-74.e2. Epub 2016 Nov 15.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163518
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http://dx.doi.org/10.1053/j.gastro.2016.09.060DOI Listing
January 2017

Loss of INI1 expression in colorectal carcinoma is associated with high tumor grade, poor survival, BRAFV600E mutation, and mismatch repair deficiency.

Hum Pathol 2016 09 14;55:83-90. Epub 2016 May 14.

Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia 2065; Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards NSW, Australia 2065; Sydney Medical School, University of Sydney, NSW, Australia 2006. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.04.018DOI Listing
September 2016

Loss of expression of BAP1 is very rare in non-small cell lung carcinoma.

Pathology 2016 Jun 21;48(4):336-40. Epub 2016 Apr 21.

Sydney Medical School, University of Sydney, St Leonards, NSW, Australia; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia; Sydney Vital Translational Research Centre, Royal North Shore Hospital, St Leonards, NSW, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00313025163396
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http://dx.doi.org/10.1016/j.pathol.2016.03.005DOI Listing
June 2016

Mutation specific immunohistochemistry is highly specific for the presence of calreticulin mutations in myeloproliferative neoplasms.

Pathology 2016 Jun 22;48(4):319-24. Epub 2016 Apr 22.

Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia; Sydney Medical School, University of Sydney, St Leonards, NSW, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia; Sydney Vital Translational Research Centre, Royal North Shore Hospital, St Leonards, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2016.03.002DOI Listing
June 2016

Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings.

Am J Surg Pathol 2016 May;40(5):599-607

*University of Sydney ¶¶Cancer Genetics, Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney †Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research §Department of Anatomical Pathology ¶Familial Cancer Clinic, Royal North Shore Hospital, St Leonards ‡Douglass Hanly Moir Pathology ∥Histopath Pathology, North Ryde #Department of Medical Oncology, Hereditary Cancer Clinic, Prince of Wales Hospital, Randwick **Department of Medical Oncology, Concord Hospital, Concord West ††Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW ‡‡Department of Anatomical Pathology, Mater Hospital, South Brisbane, Qld, Australia §§Šikl's Department of Pathology, University Hospital, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic ∥∥Department of Pathology and Laboratory Medicine, Calgary Laboratory Services, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1097/PAS.0000000000000573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830748PMC
May 2016

Loss of BAP1 expression is very rare in peritoneal and gynecologic serous adenocarcinomas and can be useful in the differential diagnosis with abdominal mesothelioma.

Hum Pathol 2016 May 29;51:9-15. Epub 2015 Dec 29.

Sydney Medical School, University of Sydney, NSW Australia 2006; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW Australia 2065; Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW Australia 2065; Sydney Vital Translational Research Centre, Royal North Shore Hospital, Pacific Highway St Leonards, NSW 2065. Electronic address:

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http://search.proquest.com/openview/e8e8602bf65cfb13d1cb0ba6
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http://linkinghub.elsevier.com/retrieve/pii/S004681771500505
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http://dx.doi.org/10.1016/j.humpath.2015.12.012DOI Listing
May 2016

A patient-derived subrenal capsule xenograft model can predict response to adjuvant therapy for cancers in the head of the pancreas.

Pancreatology 2015 Jul-Aug;15(4):397-404. Epub 2015 May 10.

Cancer Surgery Group, Kolling Institute of Medical Research, The University of Sydney, Royal North Shore Hospital, St Leonards, New South Wales, 2065, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2015.04.008DOI Listing
April 2016

Mismatch repair deficiency as a prognostic factor in mucinous colorectal cancer.

Mod Pathol 2016 Mar 15;29(3):266-74. Epub 2016 Jan 15.

Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia.

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http://dx.doi.org/10.1038/modpathol.2015.159DOI Listing
March 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:
Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965DOI Listing
March 2016

Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma.

Medicine (Baltimore) 2016 Jan;95(2):e2491

From the Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia (JA, LS, AC, MT, NW, MF, CWT, AJG); Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany (BG, MR, AS, WW, PS); Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards (LS, AC, MF, AJG); Histopath Pathology, North Ryde (CWT); Sydney Medical School, University of Sydney, Sydney (JA,CWT, RCS, AM, JSS, TJH, AJG); Upper Gastrointestinal Surgical Unit, Royal North Shore Hospital, North Shore Private Hospital, St Leonards; Discipline of Surgery, University of Sydney (AM, JSS, TJH); Macquarie University Hospital, Macquarie University, Sydney (JSS); Department of Anatomical Pathology, SYDPATH, St Vincents Hospitals, Darlinghurst, NSW, Australia (AC); Department of Pathology and Diagnostics, ARC-NET Research Center (RTL, NS, AS); Department of Surgery, University and Hospital Trust of Verona, Verona, Italy (AR); and Sydney Vital Translational Research Centre, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia (AJG).

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http://dx.doi.org/10.1097/MD.0000000000002491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718285PMC
January 2016

A further investigation of combined mismatch repair and BRAFV600E mutation specific immunohistochemistry as a predictor of overall survival in colorectal carcinoma.

PLoS One 2014 25;9(8):e106105. Epub 2014 Aug 25.

Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards, NSW, Australia; Sydney Vital Translational Research Centre, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106105PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143358PMC
December 2015

Loss of expression of BAP1 predicts longer survival in mesothelioma.

Pathology 2015 Jun;47(4):302-7

1Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, St Leonards 2Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards 3Histopath Pathology, North Ryde 4Sydney Medical School, University of Sydney, Sydney 5Sydney Vital Translational Research Centre, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia.

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http://dx.doi.org/10.1097/PAT.0000000000000250DOI Listing
June 2015

A detailed clinicopathologic study of ALK-translocated papillary thyroid carcinoma.

Am J Surg Pathol 2015 May;39(5):652-9

*Cancer Diagnosis and Pathology Research Group §§Sydney Vital Translational Research Centre, Kolling Institute of Medical Research §University of Sydney Endocrine Surgical Unit **Hormones and Cancer Group, Cancer Genetics Laboratory, Kolling Institute of Medical Research Departments of ¶Anatomical Pathology #Endocrinology, Royal North Shore Hospital, St Leonards †Department of Anatomical Pathology SYDPATH, St Vincent's Hospital ‡Kinghorn Cancer Centre and Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst ∥Histopath Pathology, North Ryde ††Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown ‡‡University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1097/PAS.0000000000000368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415964PMC
May 2015

ALK and ROS1 overexpression is very rare in colorectal adenocarcinoma.

Appl Immunohistochem Mol Morphol 2015 Feb;23(2):134-8

*Cancer Diagnosis and Pathology Group, Northern Translational Cancer Research Unit, Kolling Institute of Medical Research ∥Department of Cytogenetics, PaLMS, Royal North Shore Hospital †Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards ‡Sydney Medical School, University of Sydney, Sydney §HistoPath Pathology, North Ryde ¶Department of Anatomical Pathology, SYDPATH, St Vincent's Hospital, Darlinghurst, NSW, Australia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAI.0000000000000025DOI Listing
February 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Immunohistochemistry for myc predicts survival in colorectal cancer.

PLoS One 2014 4;9(2):e87456. Epub 2014 Feb 4.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Sydney, Australia ; Dept of Anatomical Pathology, Royal North Shore Hospital, St Leonards, Australia ; University of Sydney, Camperdown, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087456PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913591PMC
December 2014

Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients.

Am J Surg Pathol 2014 Dec;38(12):1588-602

*Department of Anatomical Pathology †Cancer Diagnosis and Pathology Research Group §§Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital ‡University of Sydney, Sydney ††Histopath Pathology ¶¶Douglass Hanly Moir Pathology, North Ryde ‡‡Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst §§§Department of Anatomical Pathology, South Western Area Pathology Service, Liverpool, NSW ∥∥Pathology Queensland, Gold Coast University Hospital, Qld ****Department of Anatomical Pathology, Royal Children's Hospital, Parkville, Vic., Australia §Department of Pathology, Medical Faculty and Charles University, Pilsen, Czech Republic ∥Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Centre, Rotterdam ##Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands ¶Department of Pathology, Singapore General Hospital, Singapore, Singapore #Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany **Department of Pathology, Oslo University Hospital ***Department of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway †††Robert J Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH ¶¶¶Department of Pathology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI ††††Laboratory of Surgical Pathology, National Cancer Institute, Bethesda, MD ‡‡‡Department of Pathology and Laboratory Medicine, Calgary Laboratory Services and University of Calgary, Calgary, AB, Canada ∥∥∥Department of Pathology, Hopital Cochin Université Paris Descartes, Paris, France ###Department of Molecular Pathology, University of Dundee, Ninewells Hospital, Dundee, UK.

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http://dx.doi.org/10.1097/PAS.0000000000000292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229399PMC
December 2014

EGFR mutation specific immunohistochemistry is a useful adjunct which helps to identify false negative mutation testing in lung cancer.

Pathology 2014 Oct;46(6):501-8

1Cancer Diagnosis and Pathology Group, Northern Translational Cancer Research Unit, Kolling Institute of Medical Research, St Leonards 2Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards 3Sydney Medical School, University of Sydney, Sydney 4HistoPath Pathology, North Ryde 5Tissue Oncology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown 6School of Medicine, University of Western Sydney, Sydney 7Department of Medical Oncology, Royal North Shore Hospital, St Leonards 8Kinghorn Cancer Centre and Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst 9University of NSW, Sydney 10Department of Anatomical Pathology, SydPath, St Vincent's Hospital, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1097/PAT.0000000000000141DOI Listing
October 2014

Reflex ALK immunohistochemistry is feasible and highly specific for ALK gene rearrangements in lung cancer.

Pathology 2014 Aug;46(5):383-8

1Cancer Diagnosis and Pathology Group, Northern Translational Cancer Research Unit, Kolling Institute of Medical Research, St Leonards 2Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards 3Sydney Medical School, University of Sydney, Sydney 4HistoPath Pathology, North Ryde 5Department of Tissue Oncology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown 6Department of Anatomical Pathology, SydPath, St Vincent's Hospital, Darlinghurst 7School of Medicine, University of Western Sydney 8Kinghorn Cancer Centre and Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1097/PAT.0000000000000114DOI Listing
August 2014

Loss of ARID1A expression in colorectal carcinoma is strongly associated with mismatch repair deficiency.

Hum Pathol 2014 Aug 24;45(8):1697-703. Epub 2014 Apr 24.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, St Leonards, NSW 2065, Australia; Sydney Medical School, University of Sydney 2050, NSW, Australia; Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, NSW 2065, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00468177140016
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http://dx.doi.org/10.1016/j.humpath.2014.04.009DOI Listing
August 2014

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

Genome Med 2013 31;5(8):78. Epub 2013 Aug 31.

Kinghorn Cancer Centre and Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia ; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK ; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.

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http://dx.doi.org/10.1186/gm482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978667PMC
May 2014

BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer.

Mod Pathol 2014 May 25;27(5):644-50. Epub 2013 Oct 25.

1] Department of Cancer Diagnosis and Pathology, Kolling Institute of Medical Research, St Leonards, NSW, Australia [2] Sydney Medical School, University of Sydney NSW, Australia [3] Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/modpathol.2013.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021849PMC
May 2014

Succinate dehydrogenase deficiency is rare in pituitary adenomas.

Am J Surg Pathol 2014 Apr;38(4):560-6

*Department of Anatomical Pathology, Royal North Shore Hospital ‡University of Sydney, Sydney †Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medial Research #Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards §Histopath Pathology, North Ryde ∥Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst, NSW ¶Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1097/PAS.0000000000000149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966922PMC
April 2014

BRAF V600E mutation specific immunohistochemistry with clone VE1 is not reliable in pituitary adenomas.

Pathology 2014 Jan;46(1):79-80

1Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards 2Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medial Research, St Leonards 3Histopath Pathology, North Ryde 4Sydney Medical School, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1097/PAT.0000000000000033DOI Listing
January 2014

von Hippel-Lindau syndrome.

Front Horm Res 2013 19;41:30-49. Epub 2013 Mar 19.

Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1159/000345668DOI Listing
December 2013

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome.

Am J Surg Pathol 2013 Oct;37(10):1592-602

*Department of Anatomical Pathology †Northern Cancer Translational Research Unit ††Familial Cancer Clinic, Royal North Shore Hospital ∥Department of Pathology, SYDPATH, St Vincents Hospital, Darlinghurst ¶Faculty of Medicine, University of NSW ¶¶Sydney Medical School, University of Sydney, Sydney, NSW §§Department of Molecular and Cellular Pathology ‡Department of Pathology, School of Medicine, University of Queensland ‡‡Envoi Specialist Pathologists, Herston §Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, QLD ∥∥Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, Vic., Australia #Department of Neuropathology, Institute of Pathology, Ruprecht-Karls University **Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0b013e31828f233dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773060PMC
October 2013

The International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society grading system has limited prognostic significance in advanced resected pulmonary adenocarcinoma.

Pathology 2013 10;45(6):553-8

*Sydney Medical School, Sydney †Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards ‡HistoPath Pathology, North Ryde §Departments of Anatomical Pathology, and ||Cardiothoracic Surgery, Royal North Shore Hospital, St Leonards, New South Wales, Australia ¶these two authors contributed equally.

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http://dx.doi.org/10.1097/PAT.0b013e32836532aeDOI Listing
October 2013

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012