Christopher T Ritchlin

Christopher T Ritchlin

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GRAPPA Trainees Symposium 2018: A Report from the GRAPPA 2018 Annual Meeting.

J Rheumatol Suppl 2019 Jun;95:4-10

From the Keck School of Medicine of the University of Southern California, Los Angeles, California; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; University of Cagliari, Rheumatology Department at Policlinico Universitario, Monserrato (Cagliari), Italy; Department of Dermatology, Division of Dermatology and Venereology, Geneva University Hospitals; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.3899/jrheum.190123DOI Listing
June 2019

Proceedings of the 2018 GRAPPA Collaborative Research Network Meeting.

J Rheumatol Suppl 2019 Jun;95:11-19

From the Rheumatology Research Unit, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; Bradford Hospitals NHS Foundation Trust, Bradford, UK; Department of Medicine, Division of Rheumatology, University of Toronto; Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Swedish Medical Center/Providence-St. Joseph Health, Seattle, Washington; University of Southern California, Los Angeles, California; University of Utah, Salt Lake City, Utah; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Conway Institute for Biomolecular Research, University College Dublin; Our Lady's Hospice and Care Services; Department of Rheumatology, St. Vincent's University Hospital, Dublin, Ireland; Department of Medical Humanities, Amsterdam University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.190118DOI Listing
June 2019

GRAPPA 2018 Project Report.

J Rheumatol Suppl 2019 Jun;95:54-57

From Kezar Life Sciences, San Francisco, California; Duke University School of Medicine, Durham, North Carolina, USA; Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland; University of Toronto; Krembil Research Institute, Psoriatic Arthritis Program, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada; UK National Institute for Health Research (NIHR), Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; Bradford Hospitals UK National Health Service (NHS) Foundation Trust, Bradford, UK; University of California at San Diego, La Jolla, California, USA; University of Alberta, Edmonton, Alberta, Canada; Rheumatology Research, Swedish Medical Center; University of Washington School of Medicine, Seattle, Washington, USA; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3899/jrheum.190121DOI Listing
June 2019

Association Between Enthesitis and Health-related Quality of Life in Psoriatic Arthritis in Biologic-naive Patients from 2 Phase III Ustekinumab Trials.

J Rheumatol 2019 Apr 1. Epub 2019 Apr 1.

From the University of Glasgow, Institute of Infection Immunity and Inflammation, Glasgow Biomedical Research Centre, Glasgow, Scotland; Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York; University of Rochester, Medical Center, Rochester, New York; Janssen Research & Development LLC, Spring House, Pennsylvania; Janssen Scientific Affairs LLC, Horsham, Pennsylvania, USA; Memorial University, St. John's, Newfoundland and Labrador, Canada; University of California-San Diego, San Diego, California, USA. This study was funded by Janssen Research & Development LLC. Janssen Biotech Inc. manufactures ustekinumab. IBM has received consulting fees from AbbVie, Janssen, Novartis, Pfizer, and UCB. LP has received consulting fees or speaker fees or served as an investigator or advisory board member for AbbVie, Almirall, Amgen, Baxalta, Biogen, Boehringer-Ingelheim, Celgene, Gebro, Janssen, Leo-Pharma, Lilly, Merck-Serono, MSD, Novartis, Pfizer, Regeneron, Roche, Sandoz, and SUN Pharmaceutical Industries. ABG has received consulting fees and served as an advisory board member for AbbVie, Janssen, Lilly, Novartis, and UCB, and has received research/educational grants from Janssen, Novartis, and UCB. CTR has received research grants, consulting fees, or speaker honoraria from AbbVie, Amgen, Janssen, Novartis, and UCB. AK has received consulting fees and research support from AbbVie, Amgen, Janssen, Lilly, Novartis, Pfizer, and UCB. PR has received consulting fees from Abbott, AbbVie, Amgen, BMS, Celgene, Janssen, Lilly, Novartis, Pfizer, and Roche. SK and GJM are or were employees of Janssen Scientific Affairs LLC when this work was performed and own stock in Johnson & Johnson, of which Janssen Research & Development LLC is a wholly-owned subsidiary. MS and YY are employees of Janssen Research & Development LLC, and own stock in Johnson & Johnson. I.B. McInnes, MD, PhD, University of Glasgow, Institute of Infection Immunity and Inflammation, Glasgow Biomedical Research Centre; L. Puig, MD, PhD, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona; A.B. Gottlieb, MD, PhD, Department of Dermatology, Icahn School of Medicine at Mount Sinai; C.T. Ritchlin, MD, MPH, University of Rochester, Medical Center; M. Song, MD, Janssen Research & Development LLC; Y. You, MS, Janssen Research & Development LLC; S. Kafka, MD, Janssen Scientific Affairs LLC; G.J. Morgan, MD, Janssen Scientific Affairs LLC; P. Rahman, MD, Memorial University; A. Kavanaugh, MD, University of California- San Diego. Address correspondence to Dr. I.B. McInnes, Institute of Infection Immunity and Inflammation, Glasgow Biomedical Research Centre, Level 4, 120 University Place, Glasgow, Scotland G12 8TA, UK. E-mail: Accepted for publication March 19, 2019.

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http://dx.doi.org/10.3899/jrheum.180792DOI Listing
April 2019

Reinterpreting Evidence of Rheumatoid Arthritis-Associated Interstitial Lung Disease to Understand Etiology.

Curr Rheumatol Rev 2019 Jan 15. Epub 2019 Jan 15.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY. United States.

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http://dx.doi.org/10.2174/1573397115666190116102451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629516PMC
January 2019

Influence of Axial Involvement on Clinical Characteristics of Psoriatic Arthritis: Analysis from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry.

J Rheumatol 2018 10 1;45(10):1389-1396. Epub 2018 Jul 1.

From the Swedish Medical Center and University of Washington, Seattle, Washington; Novartis Pharmaceuticals Corp., East Hanover, New Jersey; Corrona LLC, Waltham, Massachusetts; University of California San Diego, La Jolla, California; Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center, Rochester; New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.3899/jrheum.171094DOI Listing
October 2018

Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.

FASEB J 2018 06 17;32(6):3174-3183. Epub 2018 Jan 17.

Division of Allergy, Immunology, and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.

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http://dx.doi.org/10.1096/fj.201701379RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956243PMC
June 2018

GRAPPA Trainees Symposium 2017: A Report from the GRAPPA 2017 Annual Meeting.

J Rheumatol Suppl 2018 Jun;94:4-10

From the Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Division of Dermatology and Venereology, Geneva University Hospital; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.3899/jrheum.180130DOI Listing
June 2018

GRAPPA 2017 Project Report.

J Rheumatol Suppl 2018 Jun;94:48-51

From the University of Utah, Salt Lake City, Utah; University of California at San Diego, La Jolla, California; Rheumatology Research, Swedish Medical Center and University of Washington School of Medicine, Seattle, Washington; Department of Dermatology and Medicine, Division of Rheumatology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; New York University School of Medicine, New York; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Newman Clinical Research Professor, Department of Rheumatology, St. Vincent's University Hospital; Conway Institute for Biomolecular Research, University College Dublin; Our Lady's Hospice and Care Services, Dublin, Ireland; Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3899/jrheum.180139DOI Listing
June 2018

Proceedings of the 2017 GRAPPA Collaborative Research Network Meeting.

J Rheumatol Suppl 2018 Jun;94:54-61

From the Rheumatology Research Unit, Cambridge University Hospitals UK National Health Service (NHS) Foundation Trust, Cambridge; University of Leeds, Leeds; Bradford Hospitals NHS Foundation Trust, Bradford, UK; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto Western Hospital, Krembil Research Institute, Toronto, Ontario, Canada; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; University of Southern California, Los Angeles, California; University of Utah, Salt Lake City, Utah; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Our Lady's Hospice and Care Services; Newman Clinical Research Professor, Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland; Department of Medical Humanities, VU University Medical Centre, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.180141DOI Listing
June 2018

Gaps in Diagnosis and Treatment of Cardiovascular Risk Factors in Patients with Psoriatic Disease: An International Multicenter Study.

J Rheumatol 2018 03 1;45(3):378-384. Epub 2018 Feb 1.

From the Women's College Research Institute, Women's College Hospital; Department of Medicine, University of Toronto; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Division of Dermatology, University of Toronto, Toronto Western Hospital, Toronto; Western University, London, Ontario; University of British Columbia, Vancouver, British Columbia; Memorial University of Newfoundland, St. John's, Newfoundland; University of Manitoba; Winnipeg Clinic, Winnipeg, Manitoba, Canada; University of Michigan Medical School, Ann Arbor, Michigan; Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Rheumatology Unit, Carmel Medical Center, Haifa, Israel.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.170379
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http://dx.doi.org/10.3899/jrheum.170379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845845PMC
March 2018

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis.

Nat Rev Rheumatol 2018 02 11;14(2):94-106. Epub 2018 Jan 11.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry.

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http://dx.doi.org/10.1038/nrrheum.2017.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475908PMC
February 2018

Clinical and Patient-reported Outcomes in Patients with Psoriatic Arthritis (PsA) by Body Surface Area Affected by Psoriasis: Results from the Corrona PsA/Spondyloarthritis Registry.

J Rheumatol 2017 08 15;44(8):1151-1158. Epub 2017 Jun 15.

From the Swedish Medical Center and University of Washington (UW) Medicine, Seattle, Washington; Corrona LLC, Southborough, Massachusetts; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey; The University of Texas MD Anderson Cancer Center, Houston, Texas; University of California (UC) at San Diego, La Jolla, California; University of Rochester Medical Center, Rochester; New York University (NYU) School of Medicine, New York, New York; Scott and White Health Plan, Temple, Texas, USA.

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http://dx.doi.org/10.3899/jrheum.160963DOI Listing
August 2017

Targeting Notch-Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis.

J Bone Miner Res 2017 Jul 10;32(7):1469-1480. Epub 2017 Apr 10.

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1002/jbmr.3117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489377PMC
July 2017

GRAPPA Trainees Symposium 2016: A Report from the GRAPPA 2016 Annual Meeting.

J Rheumatol 2017 05;44(5):661-667

From the University of Toronto, Toronto, Ontario, Canada; University of Cambridge, Cambridge, UK; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Centre for Rheumatology Research, National University Hospital of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.3899/jrheum.170140DOI Listing
May 2017

Proceedings of the GRAPPA 2016 Retreat.

J Rheumatol 2017 05;44(5):668-673

From the Rheumatology Research Unit, Cambridge University Hospitals UK National Health Service (NHS) Foundation Trust, Cambridge; UK National Institute for Health Research Clinical Lecturer, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; Bradford Hospitals NHS Foundation Trust, Bradford, UK; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto Western Hospital, Krembil Research Institute; Division of Dermatology, Toronto Western Hospital, University of Toronto, Ontario; University of Alberta, Edmonton, Alberta, Canada; Rheumatology Research, Swedish Medical Center and University of Washington School of Medicine, Seattle, Washington; Advisory Services, QuintilesIMS, Denver, Colorado; Duke University School of Medicine, Durham, North Carolina; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester; New York Medical College, Valhalla; Hofstra Northwell School of Medicine, New Hyde Park, New York, New York; Medicine and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Cleveland Clinic, Cleveland, Ohio; University of Utah, Salt Lake City, Utah; University of Southern California, Los Angeles; University of California at San Diego, San Diego, California, USA; Newman Clinical Research Professor, Department of Rheumatology, St. Vincent's University Hospital; Conway Institute for Biomolecular Research, University College Dublin, Dublin, Ireland; Division of Rheumatology, University of Cagliari, Cagliari, Italy, Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Federal University of Paraná, Curitiba, Brazil.

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http://dx.doi.org/10.3899/jrheum.170141DOI Listing
May 2017

Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting.

J Rheumatol 2017 05;44(5):679-683

From Clinical Investigation, The Rockefeller University, New York; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Guy's and St. Thomas' UK National Health Service (NHS) Foundation Trust; King's College London, London, UK.

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http://dx.doi.org/10.3899/jrheum.170143DOI Listing
May 2017

International Treatment Recommendations Update: A Report from the GRAPPA 2016 Annual Meeting.

J Rheumatol 2017 05;44(5):684-685

From the UK National Institute for Health Research (NIHR), Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; PsAZZ Support Group, Bath, UK; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada; Medicine and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Cleveland Clinic, Cleveland, Ohio; Swedish Medical Center, University of Washington School of Medicine, Seattle, Washington; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York; University of California at San Diego, San Diego, California, USA; Our Lady's Hospice and Care Services, Dublin, Ireland.

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http://dx.doi.org/10.3899/jrheum.170144DOI Listing
May 2017

Psoriatic Arthritis.

N Engl J Med 2017 05;376(21):2095-6

University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1704342DOI Listing
May 2017

Psoriatic Arthritis.

N Engl J Med 2017 03;376(10):957-970

From the Allergy, Immunology, and Rheumatology Division, University of Rochester Medical School, Rochester, NY (C.T.R.); the Pediatric Translational Research Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD (R.A.C.); and the University Health Network (UHN) Krembil Research Institute, the Psoriatic Arthritis Program, and the Centre for Prognosis Studies in the Rheumatic Diseases - all at Toronto Western Hospital, Toronto (D.D.G.).

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http://dx.doi.org/10.1056/NEJMra1505557DOI Listing
March 2017

Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis.

Expert Opin Biol Ther 2017 01 30;17(1):119-128. Epub 2016 Nov 30.

a Division of Allergy, Immunology and Rheumatology, Department of Medicine , University of Rochester , Rochester , NY , USA.

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http://dx.doi.org/10.1080/14712598.2017.1263614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794005PMC
January 2017

Management of psoriatic arthritis in 2016: a comparison of EULAR and GRAPPA recommendations.

Nat Rev Rheumatol 2016 Dec 10;12(12):743-750. Epub 2016 Nov 10.

Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria; and at the 2nd Department of Medicine, Hietzing Hospital, Wolkersbergenstraße 1, 1130 Vienna, Austria.

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http://dx.doi.org/10.1038/nrrheum.2016.183DOI Listing
December 2016

Relationship Between Lymph Node Volume and Pain Following Certolizumab Therapy for Rheumatoid Arthritis Flare: A Pilot Study.

Clin Med Insights Arthritis Musculoskelet Disord 2016 14;9:203-208. Epub 2016 Dec 14.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.4137/CMAMD.S40237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158121PMC
December 2016

DC-STAMP: A Key Regulator in Osteoclast Differentiation.

J Cell Physiol 2016 11 14;231(11):2402-7. Epub 2016 Jun 14.

Division of Allergy, Immunology and Rheumatology, School of Medicine, University of Rochester, Rochester, New York.

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http://dx.doi.org/10.1002/jcp.25389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946985PMC
November 2016

Toreforant, A Histamine H4 Receptor Antagonist, in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results of 2 Phase II Studies.

J Rheumatol 2016 09 15;43(9):1637-42. Epub 2016 Jul 15.

From the Immunology department, Janssen Research & Development, LLC, San Diego, California; the Medical Affairs department, Janssen Research & Development, LLC, Horsham, Pennsylvania; the Biostatistics department and the Immunology department, Janssen Research & Development, LLC, Spring House, Pennsylvania, USA; Early Development, Janssen China Research and Development, Shanghai, China; the Biostatistics department, Janssen Research & Development, LLC, Belmont, Massachusetts, USA; Rheumatology Department, M&M Centers LTD., Adazi, Latvia; Immunology Department, University of Rochester, Rochester, New York, USA; Internal Medicine, University of Occupational and Environmental Health, Kitakyushu; Rheumatology, Keio University Hospital, Tokyo, Japan; Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria.R.L. Thurmond, PhD, Immunology Department, Janssen Research & Development, LLC; A. Greenspan, MD, Medical Affairs Department, Janssen Research & Development, LLC; W. Radziszewski, MD, PhD, Immunology Department, Janssen Research & Development, LLC; X.L. Xu, PhD, Immunology Department, Janssen Research & Development, LLC; Y. Miao, MS, Biostatistics Department, Janssen Research & Development, LLC; B. Chen, PhD, Early Development, Janssen China Research and Development; T. Ge, PhD, Biostatistics Department, Janssen Research & Development, LLC; B. Zhou, PhD, Biostatistics, Janssen Research & Development, LLC; D.G. Baker, MD, Immunology Department, Janssen Research & Development, LLC; D. Pavlova, MD, Rheumatology, M&M Centers Ltd.; C.T. Ritchlin, MD, Immunology Department, University of Rochester; Y. Tanaka, MD, PhD, Internal Medicine, University of Occupational and Environmental Health; T. Takeuchi, MD, PhD, Rheumatology, Keio University Hospital; J.S. Smolen, MD, Rheumatology, Medical University of Vienna and Hietzing Hospital.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.160164
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http://dx.doi.org/10.3899/jrheum.160164DOI Listing
September 2016

Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential.

Arthritis Res Ther 2016 09 1;18:194. Epub 2016 Sep 1.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

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http://dx.doi.org/10.1186/s13075-016-1092-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009676PMC
September 2016

Targeting the interleukin-23/17 axis in axial spondyloarthritis.

Curr Opin Rheumatol 2016 Jul;28(4):359-67

Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777167PMC
July 2016

Psoriatic Arthritis and Burden of Disease: Patient Perspectives from the Population-Based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) Survey.

Rheumatol Ther 2016 Jun 29;3(1):91-102. Epub 2016 Feb 29.

University of Rochester, School of Medicine and Dentistry, Rochester, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1007/s40744-016-0029-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999579PMC
June 2016

New therapies for psoriasis and psoriatic arthritis.

Curr Opin Rheumatol 2016 May;28(3):204-10

aUniversity of Rochester Medical Center, RochesterbMilstein Medical Research Program, Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812682PMC
May 2016

GRAPPA Trainees Symposium 2015: A Report from the GRAPPA 2015 Annual Meeting.

J Rheumatol 2016 05;43(5):952-8

From the Department of Dermatology, University of Utah, Salt Lake City, Utah, USA; Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy; Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Argentina; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA.M. Milliken, MD, MPH, Research Fellow, Department of Dermatology, University of Utah; E. Generali, MD, Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center; J. Marin, MD, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires; C.T. Ritchlin, MD, MPH, Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center.

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http://dx.doi.org/10.3899/jrheum.160113DOI Listing
May 2016

Divergent gene activation in peripheral blood and tissues of patients with rheumatoid arthritis, psoriatic arthritis and psoriasis following infliximab therapy.

PLoS One 2014 21;9(10):e110657. Epub 2014 Oct 21.

Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America; The Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204991PMC
December 2015

Etiology and Pathogenesis of Psoriatic Arthritis.

Rheum Dis Clin North Am 2015 Nov 30;41(4):643-63. Epub 2015 Aug 30.

Allergy, Immunology and Rheumatology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 695, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2015.07.006DOI Listing
November 2015

Psoriatic Arthritis.

Rheum Dis Clin North Am 2015 Nov;41(4):xiii-xiv

Allergy Immunology and Rheumatology Division, University of Rochester Medical Center, 601 Elmwood Avenue, Box 695, Rochester, NY 14621, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2015.09.001DOI Listing
November 2015

An Integrative Approach to Biomarker Development in Psoriatic Arthritis.

J Rheumatol Suppl 2015 Nov;93:43-7

From the Allergy, Immunology and Rheumatology Division, Center for Musculoskeletal Medicine, University of Rochester Medical Center, Rochester, New York, USA.C.T. Ritchlin, MD, MPH, Professor of Medicine, Chief, Allergy, Immunology and Rheumatology Division, Center for Musculoskeletal Medicine.

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http://dx.doi.org/10.3899/jrheum.150635DOI Listing
November 2015

Prevalence and Clinical Characteristics of Psoriatic Arthritis in Japan.

J Rheumatol 2015 Aug 15;42(8):1439-42. Epub 2015 Jun 15.

From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.

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http://dx.doi.org/10.3899/jrheum.141598DOI Listing
August 2015

Transient decrease in human peripheral blood myeloid dendritic cells following influenza vaccination correlates with induction of serum antibody.

Immunol Invest 2014 ;43(6):606-15

Infectious Diseases Division, University of Rochester Medical Center , Rochester NY 14642 , USA and.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589257PMC
April 2015

Validation of power Doppler versus contrast-enhanced magnetic resonance imaging quantification of joint inflammation in murine inflammatory arthritis.

J Bone Miner Res 2015 Apr;30(4):690-4

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Department of Biomedical Engineering, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

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http://dx.doi.org/10.1002/jbmr.2392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376603PMC
April 2015

Targeting extra-articular manifestations in PsA: a closer look at enthesitis and dactylitis.

Curr Opin Rheumatol 2015 Mar;27(2):111-7

Division of Allergy, Immunology & Rheumatology, University of Rochester Medical Center, Rochester, New York, USA.

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https://insights.ovid.com/crossref?an=00002281-201503000-000
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http://dx.doi.org/10.1097/BOR.0000000000000155DOI Listing
March 2015

The role of the lymphatic system in inflammatory-erosive arthritis.

Semin Cell Dev Biol 2015 Feb 15;38:90-7. Epub 2015 Jan 15.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Department of Biomedical Engineering, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Cancer Center, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Division of Allergy, Immunology, Rheumatology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States; Department of Orthopaedics, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2015.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397133PMC
February 2015

Patients with rheumatoid arthritis in clinical remission manifest persistent joint inflammation on histology and imaging studies.

J Rheumatol 2014 Nov 1;41(11):2153-60. Epub 2014 Oct 1.

From the Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center; Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.A. Anandarajah, MD, MSc, Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center; R. Thiele, MD; E. Giampoli, MD, Department of Pathology and Laboratory Medicine; J. Monu, MD, MSc; G-S. Seo, MD, Department of Musculoskeletal Radiology; C. Feng, Department of Biostatistics, University of Rochester School of Medicine and Dentistry; C.T. Ritchlin, MD, MPH, Allergy, Immunology and Rheumatology Division, University of Rochester.

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November 2014

Systematic review of treatments for psoriatic arthritis: 2014 update for the GRAPPA.

J Rheumatol 2014 Nov;41(11):2273-6

From the Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; University of California, San Diego, California; and Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA.L.C. Coates, MRCP, PhD, NIHR Clinical Lecturer, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Kavanaugh, MD, University of California; C.T. Ritchlin, MD, MPH, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center. Dr. Kavanaugh and Dr. Ritchlin contributed equally to this report.

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http://dx.doi.org/10.3899/jrheum.140875DOI Listing
November 2014

Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis.

J Rheumatol 2014 Nov;41(11):2290-4

From Johns Hopkins Arthritis Center, Baltimore, Maryland; Dermatology Associates of Rochester, Rochester, New York; Arthritis and Rheumatism Associates, Rockville, Maryland, USA; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Rheumatology, Koc University, Faculty of Medicine, Istanbul, Turkey; Department of Rheumatology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Rheumatology, Tel Aviv Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; University Hospital Leuven, Leuven, Belgium; Department of Dermatology, F.D. Roosevelt Hospital, Banska Bystrica, Slovakia; and Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA.A.M. Orbai, MD, MHS, Johns Hopkins Arthritis Center; J. Weitz, MD, Dermatology Associates of Rochester; E.L. Siegel, MD, Arthritis and Rheumatism Associates; S. Siebert, MD, Institute of Infection, Immunity and Inflammation, University of Glasgow; L.J. Savage, MD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; S.Z. Aydin, Department of Rheumatology, Koc University Faculty of Medicine; J.J. Luime, PhD, Department of Rheumatology, Erasmus Medical Center; O. Elkayam, MD, Department of Rheumatology, Tel Aviv Medical Center and Sackler Faculty of Medicine; B. Neerinckx, MD, University Hospital Leuven; S. Urbancek, MD, PhD, Department of Dermatology, F.D. Roosevelt Hospital; K. de Vlam, MD, PhD, University Hospital Leuven; C.T. Ritchlin, MD, MPH, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center.

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November 2014

GRAPPA Trainees Symposium 2013: a report from the GRAPPA 2013 Annual Meeting.

J Rheumatol 2014 Jun;41(6):1200-5

From the Department of Rheumatology, St. Vincent's University Hospital, Dublin, Ireland; University of California Davis, Department of Dermatology, Davis, California; and Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA.A. Szentpetery, MD, Department of Rheumatology, St. Vincent's University Hospital; M.A.N. Johnson, MD, University of California Davis, Department of Dermatology; C.T. Ritchlin, MD, MPH, Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center.

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http://dx.doi.org/10.3899/jrheum.140170DOI Listing
June 2014

Psoriatic enthesitis: an update from the GRAPPA 2013 Annual Meeting.

J Rheumatol 2014 Jun;41(6):1220-3

From the Allergy, Immunology, and Rheumatology Division, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.C.T. Ritchlin, MD, MPH, Professor of Medicine.

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http://dx.doi.org/10.3899/jrheum.140174DOI Listing
June 2014

GRAPPA treatment recommendations: an update from the GRAPPA 2013 Annual Meeting.

J Rheumatol 2014 Jun;41(6):1237-9

From the Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York; and the University of California at San Diego, California, USA.L.C. Coates, MRCP, PhD, UK National Institute for Health Research Clinical Lecturer, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; C.T. Ritchlin, MD, MPH, Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center; A.F. Kavanaugh, MD, Professor of Medicine, University of California at San Diego.

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http://dx.doi.org/10.3899/jrheum.140179DOI Listing
June 2014

Brodalumab, an anti-IL17RA monoclonal antibody, in psoriatic arthritis.

N Engl J Med 2014 Jun;370(24):2295-306

From the Swedish Medical Center and University of Washington, Seattle (P.J.M.); Oregon Health and Science University, Portland (A.D.); Stanford University, Palo Alto (M.C.G.), Desert Medical Advances, Palm Desert (M.W.G.), and Amgen, Thousand Oaks (R.N., J.Y.F., N.E., A.N.) - all in California; University of Rochester Medical Center, Rochester, NY (C.T.R.); and Laval University, Quebec, QC, Canada (A.D.B.).

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http://dx.doi.org/10.1056/NEJMoa1315231DOI Listing
June 2014

Ustekinumab : targeting the IL-17 pathway to improve outcomes in psoriatic arthritis.

Expert Opin Biol Ther 2014 Apr 20;14(4):515-26. Epub 2014 Feb 20.

University of Rochester Medical Center, Division of Allergy/Immunology & Rheumatology , 601 Elmwood Ave, Box 695, Rochester, NY 14623 , USA

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http://dx.doi.org/10.1517/14712598.2014.890587DOI Listing
April 2014

In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice.

J Physiol 2014 Mar 13;592(6):1213-23. Epub 2014 Jan 13.

The Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.

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http://doi.wiley.com/10.1113/jphysiol.2013.266700
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961082PMC
March 2014

Proceedings of the 5th annual perspectives in rheumatic diseases.

Semin Arthritis Rheum 2013 Dec;43(3):416-9

UCLA Rheumatology, 1000 Veteran Ave, Room 32-59 Rehab, Los Angeles, CA 90095. Electronic address:

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December 2013

Mechanistic insights from animal models of psoriasis and psoriatic arthritis.

Curr Rheumatol Rep 2013 Nov;15(11):377

Division of Allergy/Immunology and Rheumatology, University of Rochester Medical Center, 601 Elmwood Ave. Box 695, Rochester, NY, 14642, USA,

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November 2013

Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice.

Genesis 2013 Sep 9;51(9):667-75. Epub 2013 Jul 9.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1002/dvg.22407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787964PMC
September 2013

GRAPPA Trainees Symposium 2012: a report from the GRAPPA 2012 annual meeting.

J Rheumatol 2013 Aug;40(8):1413-8

Division of Arthritis and Rheumatism, Oregon Health and Sciences University, Portland, Oregon, USA.

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http://dx.doi.org/10.3899/jrheum.130452DOI Listing
August 2013

Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow.

Arthritis Rheum 2013 Jan;65(1):130-8

University of Rochester School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1002/art.37709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535508PMC
January 2013

GRAPPA Trainees Symposium 2011: a report from the GRAPPA 2011 annual meeting.

J Rheumatol 2012 Nov;39(11):2184-8

Division of Rheumatic and Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.120819
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November 2012

Biomarkers of radiographic progression in psoriatic arthritis: a report from the GRAPPA 2011 annual meeting.

J Rheumatol 2012 Nov;39(11):2189-92

Department of Rheumatology, St. Vincent's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.3899/jrheum.120820DOI Listing
November 2012

Altered bone biology in psoriatic arthritis.

Curr Rheumatol Rep 2012 Aug;14(4):349-57

Department of Pediatrics, Division of Rheumatology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 777, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1007/s11926-012-0259-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387493PMC
August 2012

GRAPPA Trainees Symposium 2010: a report from the GRAPPA 2010 annual meeting.

J Rheumatol 2012 Feb;39(2):394-7

Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.111232
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February 2012

Strategies for biomarker development in psoriatic disease: a report from the GRAPPA 2010 annual meeting.

J Rheumatol 2012 Feb;39(2):423-6

Allergy, Immunology, and Rheumatology Division, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

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February 2012

The path forward to biomarker discovery in psoriatic disease: a report from the GRAPPA 2010 annual meeting.

J Rheumatol 2012 Feb;39(2):434-6

University of Toronto and Toronto Western Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.111243DOI Listing
February 2012

Biomarkers to Diagnose Early Arthritis in Patients With Psoriasis.

Psoriasis Forum 2012 ;18(2):2-10

Allergy/Immunology & Rheumatology, University of Rochester Medical School, Rochester, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241968PMC
January 2012

Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes.

Ann N Y Acad Sci 2011 Dec;1240:47-52

Center for Musculoskeletal Research, Department of Biomedical Engineering, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

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http://doi.wiley.com/10.1111/j.1749-6632.2011.06237.x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334848PMC
December 2011

The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis.

Adv Exp Med Biol 2010 ;658:1-10

The Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://link.springer.com/10.1007/978-1-4419-1050-9_1
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http://dx.doi.org/10.1007/978-1-4419-1050-9_1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932510PMC
August 2011

CD23(+)/CD21(hi) B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice.

Arthritis Res Ther 2011 Aug 31;13(4):R138. Epub 2011 Aug 31.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1186/ar3452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239381PMC
August 2011

GRAPPA Trainees Symposium 2009: a report from the GRAPPA 2009 annual meeting.

J Rheumatol 2011 Mar;38(3):526-9

Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds LS7 4SA, UK.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.101114
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March 2011

CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis.

Arthritis Res Ther 2010 26;12(1):R14. Epub 2010 Jan 26.

Allergy/Immunology & Rheumatology Unit, University of Rochester Medical School, 601 Elmwood Avenue, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1186/ar2915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875642PMC
August 2010

RANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens.

J Cell Physiol 2010 Apr;223(1):76-83

Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1002/jcp.22012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814997PMC
April 2010

Mediation of nonerosive arthritis in a mouse model of lupus by interferon-alpha-stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis.

Arthritis Rheum 2010 Apr;62(4):1127-37

University of Rochester Medical Center and University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

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http://dx.doi.org/10.1002/art.27312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854832PMC
April 2010

Biomarkers in psoriasis and psoriatic arthritis: GRAPPA 2008.

J Rheumatol 2010 Feb;37(2):462-7

Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.3899/jrheum.090957DOI Listing
February 2010

The diagnosis and treatment of early psoriatic arthritis.

Nat Rev Rheumatol 2009 Nov 6;5(11):634-41. Epub 2009 Oct 6.

Clinical Immunology Research Center, Allergy, Immunology & Rheumatology Research Division, University of Rochester Medical Center, 601 Elmwood Avenue, P. O. Box 695, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1038/nrrheum.2009.210DOI Listing
November 2009

Translational perspectives on psoriatic arthritis.

J Rheumatol Suppl 2009 Aug;83:30-4

University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.3899/jrheum.090219DOI Listing
August 2009