Christopher R Levi

Christopher R Levi

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Christopher R Levi

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Comparing mismatch strategies for patients being considered for ischemic stroke tenecteplase trials.

Int J Stroke 2019 Nov 4:1747493019884529. Epub 2019 Nov 4.

Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1177/1747493019884529DOI Listing
November 2019

Dynamic CT but Not Optimized Multiphase CT Angiography Accurately Identifies CT Perfusion Target Mismatch Ischemic Stroke Patients.

Front Neurol 2019 23;10:1130. Epub 2019 Oct 23.

Department of Neurology, The Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fneur.2019.01130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819495PMC
October 2019

Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis.

Neurology 2019 Jul 17;93(3):e283-e292. Epub 2019 Jun 17.

From the Department of Neurology (C.C., C.R.L., N.J.S., F.M., L.L.), John Hunter Hospital; University of Newcastle (C.C., C.R.L., N.J.S., F.M., L.L.); Hunter Medical Research Institute (C.C., C.R.L., N.J.S., F.M., L.L.), Newcastle; Department of Neurology (M.W.P., A.B.), Royal Melbourne Hospital, Melbourne Brain Centre, University of Melbourne, Australia; Department of Neurology (X.C., Q.D.), Huashan Hospital, Fudan University, Shanghai; Department of Neurology (M.L.), Second Affiliated Hospital of Zhejiang University, Hangzhou, China; Department of Neurology (T.K.), Royal Adelaide Hospital, Australia; and Division of Neurology (K.B.), Department of Medicine, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000007768DOI Listing
July 2019

Modafinil treatment modulates functional connectivity in stroke survivors with severe fatigue.

Sci Rep 2019 Jul 4;9(1):9660. Epub 2019 Jul 4.

Department of Neurology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1038/s41598-019-46149-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609702PMC
July 2019

Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke.

Neurology 2019 Jun 1;92(23):e2626-e2643. Epub 2019 May 1.

From the Department of Neurology (H.T., M.W.P., C.R.L., L.L., N.J.S., A.B.), John Hunter Hospital, University of Newcastle, Australia; Department of Medical Imaging, Division of Neuroradiology (R.I.A.), Sunnybrook Health Sciences Center and University of Toronto; Division of Neurology, Department of Medicine (K.S.B.), University of Alberta, Edmonton, Canada; Department of Neurology (M.L.), the Second Affiliated Hospital of Zhejiang University, Hangzhou, China; and Department of Neurology (T.J.K.), Royal Adelaide Hospital, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007553DOI Listing
June 2019

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.

N Engl J Med 2019 05;380(19):1795-1803

From Florey Institute of Neuroscience and Mental Health (H.M., L. Churilov, N.Y., V.T., L. Carey, A.M., G.A.D.), the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital (B.C.V.C., M.W.P., L. Churilov, S. Christensen, N.Y., G.S., A.B., B.Y., A.M., S.M.D., G.A.D.), and the Department of Radiology, Royal Melbourne Hospital (P.M.D., B.Y., P.J.M.), University of Melbourne, Parkville, the Department of Medicine, School of Clinical Science, Monash University, Clayton (H.M., T.G.P.), the Departments of Medicine and Neurology, Melbourne Medical School, University of Melbourne and Western Health, Sunshine Hospital, St. Albans (T.W.), the Department of Neurosciences, Eastern Health and Eastern Health Clinical School, Monash University, Box Hill (H.M.D., C.F.B.), the Department of Neurology, University Hospital Geelong, Deakin University, Geelong (B.C.), the Department of Neurology, Austin Hospital, Austin Health, Heidelberg (V.T.), and Occupational Therapy, School of Allied Health, College of Science, Health and Engineering, La Trobe University, Bundoora (L. Carey), VIC, the Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital (C.R.L., F.M.), University of Newcastle (J.S.), Newcastle, the Department of Neurology, Westmead Hospital (N.M.), the Department of Neurology, Royal North Shore Hospital and Kolling Institute, University of Sydney (M.K.), and the Department of Neurology, St. Vincent's Hospital Sydney (R.M.), Sydney, and the Department of Neurology, Gosford Hospital, Gosford (J.S.), NSW, the Department of Neurology, Royal Adelaide Hospital (T.J.K., J.J.), the Department of Neurology, Lyell McEwin Hospital (D.F.), and the Department of Neurology, Queen Elizabeth Hospital (J.J.), Adelaide, SA, the Department of Medicine, Sunshine Coast University Hospital, Nambour (R.G.), the Department of Neurology, Royal Brisbane and Women's Hospital and the University of Queensland, Brisbane (A.A.W.), and the Department of Neurology, Gold Coast University Hospital, Southport (A.S.), and Australia and Griffith University, Gold Coast (A.S.), QLD - all in Australia; the Graduate Institute of Clinical Medical Science (C.H.) and the School of Medicine (C.-H.T.), China Medical University, and the Department of Neurology, China Medical University Hospital (C.-H.T.), Taichung, the Department of Neurology, Tri-Service General Hospital, National Defense Medical Center (J.-T.L.), the Department of Neurology, Shuang Ho Hospital (C.-J.H.), the Department of Neurology, En Chu Kong Hospital (Y.S.), the Stroke Center and Department of Neurology, National Taiwan University Hospital (J.-S.J.), and the Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei Medical University College of Medicine (L.-M.L.), Taipei, the Stroke Center and Department of Neurology, Changhua Christian Hospital, Changhua (M.-C.S.), the Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan (C.-H.C.), and the Department of Neurology, Kaohsiung Veterans General Hospital, Kaohsiung (C.-H.L.) - all in Taiwan; the Department of Neurology, Helsinki University Hospital, Helsinki (S. Curtze, A.M.); the Department of Neurology, Auckland City Hospital, University of Auckland, Auckland, New Zealand (P.A.B.); and the Stanford Stroke Center, Stanford University, Stanford, CA (S. Christensen).

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http://www.nejm.org/doi/10.1056/NEJMoa1813046
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http://dx.doi.org/10.1056/NEJMoa1813046DOI Listing
May 2019

Thresholds for infarction vary between gray matter and white matter in acute ischemic stroke: A CT perfusion study.

J Cereb Blood Flow Metab 2019 Mar 27;39(3):536-546. Epub 2017 Nov 27.

1 Priority Research Centre for Stroke and Brain Injury, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia.

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http://dx.doi.org/10.1177/0271678X17744453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421247PMC
March 2019

Predicting Modafinil-Treatment Response in Poststroke Fatigue Using Brain Morphometry and Functional Connectivity.

Stroke 2019 03;50(3):602-609

Department of Neurology, John Hunter Hospital (T.P.L., C.G.-E., N.J.S., M.W.P., C.R.L., A.B.), University of Newcastle, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.118.023813DOI Listing
March 2019

Video and clinical screening of national rugby league players suspected of sustaining concussion.

Brain Inj 2017 5;31(13-14):1918-1924. Epub 2017 Sep 5.

g Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital , MassGeneral Hospital for Children™ Sports Concussion Program, & Home Base, A Red Sox Foundation and Massachusetts General Hospital Program , Boston , Massachusetts , USA.

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http://dx.doi.org/10.1080/02699052.2017.1358399DOI Listing
July 2018

Correction for Delay and Dispersion Results in More Accurate Cerebral Blood Flow Ischemic Core Measurement in Acute Stroke.

Stroke 2018 04 2;49(4):924-930. Epub 2018 Mar 2.

From the School of Medicine and Public Health, University of Newcastle, Australia (L.L., A.B., N.J.S., C.R.L., M.W.P.); Department of Neurology, Royal Adelaide Hospital, Australia (T.K.); Department of Neurology, John Hunter Hospital, Newcastle, Australia (N.J.S., C.R.L., M.W.P.); and Apollo Medical Imaging Technology Pty Ltd, Melbourne, VIC, Australia (Q.Y.).

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.019562
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http://dx.doi.org/10.1161/STROKEAHA.117.019562DOI Listing
April 2018

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke.

N Engl J Med 2018 04;378(17):1573-1582

From the Departments of Medicine and Neurology, Melbourne Brain Centre (B.C.V.C., N.Y., B.Y., T.Y.W., D.G.S., E.R., H.Z., P.S., G.S., M.W.P., S.M.D.), and the Department of Radiology (P.J.M., R.J.D., S.J.B., P.M.D.), Royal Melbourne Hospital, and the Florey Institute of Neuroscience and Mental Health (L.C., N.Y., V.T., H.A., H.M., C.F.B., G.A.D.), University of Melbourne, Parkville, VIC, the Departments of Neurology (T.J.K.) and Radiology (R.S.), Royal Adelaide Hospital, and the Department of Neurology, Lyell McEwin Hospital (D.F.), Adelaide, SA, the Department of Neurosciences, Eastern Health and Eastern Health Clinical School (H.M.D., C.F.B.), and the Departments of Neurology (H.M., T.G.P.) and Radiology (W. Chong, R.V.C., L.-A.S.), Monash Medical Centre, Monash University, Clayton, VIC, the Departments of Neurology (V.T., M.S.) and Radiology (M.B., H.A.), Austin Hospital, Austin Health, Heidelberg, VIC, School of Medicine, Faculty of Health, Deakin University, Melbourne, VIC (H.A.), and the Departments of Medicine and Neurology, Melbourne Medical School, University of Melbourne and Western Health, Sunshine Hospital, St. Albans, VIC (T.W.), the Departments of Neurology (D.G.S., H.B.) and Radiology (K.R., D.L.), Princess Alexandra Hospital, and the Departments of Neurology (A.A.W., C.M.) and Radiology (A.C., K. Mitchell, J.C., K. Mahady), Royal Brisbane and Women's Hospital and the University of Queensland, Brisbane, the Departments of Neurology (P.B.) and Radiology (H.R., L.V.), Gold Coast University Hospital, Southport, QLD, and the Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle, Newcastle, NSW (T.A., F.M., C.R.L., C.G.-E., M.W.P.), the Department of Neurology, Royal North Shore Hospital and Kolling Institute, University of Sydney (M.K.), and the Department of Radiology, Royal North Shore Hospital (T.J.H., K.C.F., B.S.S.), St. Leonards, and the Department of Radiology, Westmead Hospital, Sydney (T.J.H., K.C.F., B.S.S.) - all in Australia; and the Departments of Neurology (T.Y.W., J.N.F.) and Radiology (W. Collecutt), Christchurch Hospital, Christchurch, New Zealand.

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http://dx.doi.org/10.1056/NEJMoa1716405DOI Listing
April 2018

Transient Ischemic Attack Results in Delayed Brain Atrophy and Cognitive Decline.

Stroke 2018 02 4;49(2):384-390. Epub 2018 Jan 4.

From the Department of Neurology, John Hunter Hospital (A.B., T.L., C.G.-E., V.K., C.R.L., M.P.) and Hunter Medical Research Institute (A.B., T.L., C.G.-E., E.H., V.K., C.R.L., M.P.), University of Newcastle, New South Wales, Australia; Advanced Clinical Imaging Technology, Siemens Healthcare HC CEMEA SUI DI PI, Lausanne, Switzerland (B.M.); Department of Radiology, CHUV, Lausanne, Switzerland (B.M.); and LTS5, EPFL, Lausanne, Switzerland (B.M.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019276DOI Listing
February 2018

Observational Review and Analysis of Concussion: a Method for Conducting a Standardized Video Analysis of Concussion in Rugby League.

Sports Med Open 2017 Dec 14;3(1):26. Epub 2017 Jul 14.

Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1186/s40798-017-0093-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511124PMC
December 2017

Influence of Penumbral Reperfusion on Clinical Outcome Depends on Baseline Ischemic Core Volume.

Stroke 2017 10 8;48(10):2739-2745. Epub 2017 Sep 8.

From the Department of Neurology, John Hunter Hospital, University of Newcastle, Australia (C.C., M.P., C.L., L.L., A.B.); Public Health Stream, Hunter Medical Research Institute, Newcastle, Australia (M.C., C.O.); Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China (X.C., Q.D.); Department of Neurology, Second Affiliated Hospital of Zhejiang University, Hangzhou, China (M.L.); Department of Neurology, Royal Adelaide Hospital, Australia (T.K.); and Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Canada (K.B.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018587DOI Listing
October 2017

Managing transient ischaemic attacks in Australia: a qualitative study.

Fam Pract 2017 09;34(5):606-611

Discipline of General Practice, University of Newcastle, Newcastle, Australia.

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http://academic.oup.com/fampra/article/34/5/606/3603585/Mana
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http://dx.doi.org/10.1093/fampra/cmx030DOI Listing
September 2017

Visibility of CT Early Ischemic Change Is Significantly Associated with Time from Stroke Onset to Baseline Scan beyond the First 3 Hours of Stroke Onset.

J Stroke 2017 Sep 29;19(3):340-346. Epub 2017 Sep 29.

Department of Neurology, John Hunter Hospital, University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.5853/jos.2016.01424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647641PMC
September 2017

Evidence of Concussion Signs in National Rugby League Match Play: a Video Review and Validation Study.

Sports Med Open 2017 Aug 22;3(1):29. Epub 2017 Aug 22.

Center for Health and Rehabilitation, Department of Physical Medicine and Rehabilitation, Harvard Medical School, 79/96 Thirteenth Street, Charlestown Navy Yard, Charlestown, MA, USA.

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http://dx.doi.org/10.1186/s40798-017-0097-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567587PMC
August 2017

Tenecteplase in ischemic stroke offers improved recanalization: Analysis of 2 trials.

Neurology 2017 Jul 2;89(1):62-67. Epub 2017 Jun 2.

From the Department of Neurology (A.B., C.R.L., N.S., M.W.P.), John Hunter Hospital, University of Newcastle, Australia; Institute of Neuroscience and Psychology, Queen Elizabeth University Hospital (X.H., B.K.C., D.K., F.C.M., I.F., K.W.M.), and Robertson Centre for Biostatistics (I.F.), University of Glasgow, UK; Department of Medicine and Neurology, Royal Melbourne Hospital (B.C.V.C., S.M.D.), and The Florey Institute of Neuroscience & Mental Health (C.F.B., G.A.D.), University of Melbourne, Parkville; and the Department of Neurology (C.F.B.), Eastern Health Clinical School, Monash University, Clayton, Australia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004062DOI Listing
July 2017

Quantifying reperfusion of the ischemic region on whole-brain computed tomography perfusion.

J Cereb Blood Flow Metab 2017 Jun 1;37(6):2125-2136. Epub 2016 Jan 1.

1 School of Medicine and Public health, University of Newcastle, Newcastle, Australia.

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http://dx.doi.org/10.1177/0271678X16661338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464706PMC
June 2017

MIDAS (Modafinil in Debilitating Fatigue After Stroke): A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial.

Stroke 2017 05 12;48(5):1293-1298. Epub 2017 Apr 12.

From the Departments of Neurology, John Hunter Hospital (A.B., T.L., V.K., M.P., C.R.L.), Hunter Medical Research Institute (A.B., T.L., V.K., E.H., J.A., H.P., M.N., M.P., C.R.L.), and Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health (J.A.), University of Newcastle, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.116.016293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404401PMC
May 2017

Quality of Acute Care and Long-Term Quality of Life and Survival: The Australian Stroke Clinical Registry.

Stroke 2017 04 3;48(4):1026-1032. Epub 2017 Mar 3.

From the Stroke and Ageing Research, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia (D.A.C., N.E.A.); Florey Institute Neuroscience and Mental Health, Heidelberg, University of Melbourne, Victoria, Australia (D.A.C., B.G., C.F.B., G.A.D.); College of Science, Health and Engineering, School of Allied Health, La Trobe University, Bundoora, Victoria, Australia (N.A.L.); Occupational Therapy Department, Alfred Health, Prahran, Victoria, Australia (N.A.L.); Nursing Research Institute, St Vincent's Health Australia (Sydney) and Australian Catholic University, New South Wales (S.M.); Priority Research Centre for Translational Neurosciences Mental Health Research, University of Newcastle and Hunter Research Institute, New South Wales, Australia (C.R.L.); Eastern Health Clinical School, Monash University, Box Hill, Victoria, Australia (H.M.D., C.F.B.); Faculty of Medicine, The University of New South Wales, Sydney and St Vincent's Hospital, Darlinghurst, Australia (S.F.); National Stroke Foundation, Melbourne, Victoria, Australia (K.H.); University of Queensland, Brisbane, Australia (R.G., A.W.); Neurology Department, Royal Brisbane and Women's Hospital, Queensland, Australia (A.W.); Neurology Department, Gold Coast Hospital, Queensland, Australia (A.S.); Neurology Department, Peninsula Health, Frankston, Victoria, Australia (E.B.); Swan District Hospital and University of Western Australia, Perth, Australia (T.R.B.); South West Healthcare, Warrnambool, Victoria, Australia (P.G.); Neurology Department, Royal Hobart Hospital, Hobart, Tasmania, Australia (H.C.); The George Institute for Global Health, The University of Sydney, New South Wales, Australia (C.S.A.); and Neurology Department, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia (C.S.A.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015714DOI Listing
April 2017

Age-related decline in task switching is linked to both global and tract-specific changes in white matter microstructure.

Hum Brain Mapp 2017 03 23;38(3):1588-1603. Epub 2016 Nov 23.

Functional Neuroimaging Laboratory, School of Psychology, University of Newcastle, Newcastle, Australia.

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http://dx.doi.org/10.1002/hbm.23473DOI Listing
March 2017

Perfusion computed tomography in patients with stroke thrombolysis.

Brain 2017 03;140(3):684-691

Departments of Neurology, John Hunter Hospital, University of Newcastle, Lookout Road, New Lambton Heights, NSW 2305, Australia.

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http://dx.doi.org/10.1093/brain/aww338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382947PMC
March 2017

MR Spectroscopy Findings in Retired Professional Rugby League Players.

Int J Sports Med 2017 Mar 13;38(3):241-252. Epub 2017 Feb 13.

School of Health Sciences, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1055/s-0042-120843DOI Listing
March 2017

The Basilar Artery on Computed Tomography Angiography Prognostic Score for Basilar Artery Occlusion.

Stroke 2017 03 22;48(3):631-637. Epub 2017 Feb 22.

From the Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (F.A., D.G.S., B.Y., S.M.D., B.C.V.C.); Department of Neurology (F.A., M.D., F.S., C.C.) and Department of Diagnostic Imaging and Interventional Radiology (R.F.), University Hospital Tor Vergata, Rome, Italy; I.R.C.C.S., Santa Lucia Foundation, Rome, Italy (M.D., C.C.); Department of Neurology, John Hunter Hospital, University of Newcastle, Australia (A.B., M.W.P., C.R.L.); and Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (G.S., P.J.M., R.J.D., S.B.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015492DOI Listing
March 2017

Seasonal variation in cervical artery dissection in the Hunter New England region, New South Wales, Australia: A retrospective cohort study.

Musculoskelet Sci Pract 2017 02 20;27:106-111. Epub 2016 Oct 20.

Faculty of Health and Medicine, The University of Newcastle, Australia; Hunter Medical Research Institute, Newcastle, Australia.

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http://dx.doi.org/10.1016/j.math.2016.10.007DOI Listing
February 2017

Seasonal Variation in Spontaneous Cervical Artery Dissection: Comparing between UK and Australian Sites.

J Stroke Cerebrovasc Dis 2017 Jan 10;26(1):177-185. Epub 2016 Oct 10.

Faculty of Health and Medicine, The University of Newcastle, New South Wales, Australia; Hunter Medical Research Institute, Newcastle, New South Wales, Australia; John Hunter Hospital, New Lambton Heights, Australia.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.09.006DOI Listing
January 2017

Impact of Computed Tomography Perfusion Imaging on the Response to Tenecteplase in Ischemic Stroke: Analysis of 2 Randomized Controlled Trials.

Circulation 2017 Jan 13;135(5):440-448. Epub 2016 Dec 13.

From Department of Neurology, John Hunter Hospital, University of Newcastle, Australia (A.B., P.M., C.R.L., M.W.D.); Institute of Neuroscience and Psychology, University of Glasgow, Queen Elizabeth University Hospital, Scotland, UK (X.H., B.K.C., D.K., F.C.M., I.F., K.W.M.); Department of Medicine and Neurology, Royal Melbourne Hospital (B.C.V.C., S.M.D.), and The Florey Institute of Neuroscience and Mental Health (C.F.B., G.A.D.), University of Melbourne, Australia; and Department of Neurology, Eastern Health Clinical School, Monash University, Melbourne, Australia (C.F.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022582DOI Listing
January 2017

Collaborative Patient-Centered Quality Improvement: A Cross-Sectional Survey Comparing the Types and Numbers of Quality Initiatives Selected by Patients and Health Professionals.

Eval Health Prof 2016 12 1;39(4):475-495. Epub 2016 Aug 1.

Department of Neurology, John Hunter Hospital and Research Support and Development Unit, Hunter New England Local Health District, New Lambton, New South Wales, Australia.

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http://dx.doi.org/10.1177/0163278716659524DOI Listing
December 2016

Whole-Brain CT Perfusion to Quantify Acute Ischemic Penumbra and Core.

Radiology 2016 Jun 18;279(3):876-87. Epub 2016 Jan 18.

From the School of Medicine and Public Health, University of Newcastle, Newcastle, Australia (L.L., A.B., V.K., C.R.L., M.W.P.); and Department of Neurology, John Hunter Hospital, University of Newcastle, Newcastle, Australia (V.K., C.R.L., M.W.P.).

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http://dx.doi.org/10.1148/radiol.2015150319DOI Listing
June 2016

Better outcomes for hospitalized patients with TIA when in stroke units: An observational study.

Neurology 2016 May 4;86(22):2042-8. Epub 2016 May 4.

From Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000002715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891210PMC
May 2016

Relationship Between Collateral Status, Contrast Transit, and Contrast Density in Acute Ischemic Stroke.

Stroke 2016 Mar 2;47(3):742-9. Epub 2016 Feb 2.

From the Department of Neurology, John Hunter Hospital, Hunter Medical Research Institute, and the University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.115.011320DOI Listing
March 2016

Microstructural white matter changes mediate age-related cognitive decline on the Montreal Cognitive Assessment (MoCA).

Psychophysiology 2016 Feb 29;53(2):258-67. Epub 2015 Oct 29.

Functional Neuroimaging Laboratory, School of Psychology, Faculty of Science & IT, University of Newcastle, Newcastle, Australia.

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http://doi.wiley.com/10.1111/psyp.12565
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http://dx.doi.org/10.1111/psyp.12565DOI Listing
February 2016

Thrombolytic Recanalization of Carotid Arteries Is Highly Dependent on Degree of Stenosis, Despite Sonothrombolysis.

J Am Heart Assoc 2016 Feb 23;5(2). Epub 2016 Feb 23.

School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW, Australia Hunter Medical Research Institute, New Lambton, NSW, Australia Hunter New England Local Health District Newcastle, Newcastle, NSW, Australia

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https://www.ahajournals.org/doi/10.1161/JAHA.115.002716
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http://dx.doi.org/10.1161/JAHA.115.002716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802445PMC
February 2016

Tissue Plasminogen Activator for preclinical stroke research: Neither "rat" nor "human" dose mimics clinical recanalization in a carotid occlusion model.

Sci Rep 2015 Nov 2;5:16026. Epub 2015 Nov 2.

School of Biomedical Sciences &Pharmacy, Medical Sciences Building, University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1038/srep16026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629197PMC
November 2015

A preliminary video analysis of concussion in the National Rugby League.

Brain Inj 2015 Sep 17;29(10):1182-1185. Epub 2015 Jun 17.

k Centre for Translational Neuroscience & Mental Health, School of Health Sciences, Faculty of Health, University of Newcastle , Callaghan, New South Wales , Australia.

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http://dx.doi.org/10.3109/02699052.2015.1034179DOI Listing
September 2015

Cerebrovascular reactivity assessed by transcranial Doppler ultrasound in sport-related concussion: a systematic review.

Br J Sports Med 2015 Aug 1;49(16):1050-5. Epub 2014 Dec 1.

Department of Physical Medicine and Rehabilitation, Harvard Medical School; Spaulding Rehabilitation Hospital, MassGeneral Hospital for Children Sports Concussion Program, & Red Sox Foundation and Massachusetts General Hospital Home Base Program, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/bjsports-2014-093901DOI Listing
August 2015

The spectacular recent trials of urgent neurointervention for acute stroke: fuel for a revolution.

Med J Aust 2015 Jul;203(2):58-60

John Hunter Hospital, Newcastle, NSW, Australia.

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http://dx.doi.org/10.5694/mja15.00395DOI Listing
July 2015

A systematic review of concussion in rugby league.

Br J Sports Med 2015 Apr 10;49(8):495-8. Epub 2014 Apr 10.

Faculty of Health & Medicine, School of Health Sciences, University of Newcastle, Callaghan, New South Wales, Australia.

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April 2015

Platelet rich clots are resistant to lysis by thrombolytic therapy in a rat model of embolic stroke.

Exp Transl Stroke Med 2015 27;7. Epub 2015 Jan 27.

School of Biomedical Sciences & Pharmacy, University of Newcastle, and Hunter Medical Research Institute, Newcastle, Australia ; Hunter New England Local Health District, Newcastle, Australia.

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http://dx.doi.org/10.1186/s13231-014-0014-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318170PMC
February 2015

Spectroscopy of reperfused tissue after stroke reveals heightened metabolism in patients with good clinical outcomes.

J Cereb Blood Flow Metab 2014 Dec 1;34(12):1944-50. Epub 2014 Oct 1.

Department of Neurology, John Hunter Hospital, Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1038/jcbfm.2014.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269749PMC
December 2014

Characteristics of exercise training interventions to improve cardiorespiratory fitness after stroke: a systematic review with meta-analysis.

Neurorehabil Neural Repair 2013 Nov-Dec;27(9):775-88. Epub 2013 Jul 24.

1University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.1177/1545968313496329DOI Listing
July 2014

Are patients with intracerebral haemorrhage disadvantaged in hospitals?

Int J Stroke 2014 Jun 21;9(4):437-42. Epub 2013 Nov 21.

Barwon Health, Geelong, VIC, Australia; La Trobe University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1111/ijs.12223DOI Listing
June 2014

Comparison of computed tomographic and magnetic resonance perfusion measurements in acute ischemic stroke: back-to-back quantitative analysis.

Stroke 2014 Jun 13;45(6):1727-32. Epub 2014 May 13.

From the Stroke Research Program, Hunter Medical Research Institute (L.L., A.B., C.R.L., M.W.P.) and Department of Neurology, John Hunter Hospital (C.R.L., M.W.P.), The University of Newcastle, Newcastle, New South Wales, Australia.

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.114.
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http://dx.doi.org/10.1161/STROKEAHA.114.005419DOI Listing
June 2014

Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats.

Fluids Barriers CNS 2014 6;11:12. Epub 2014 Jun 6.

University of Newcastle and Hunter Medical Research Institute, University of Newcastle: School of Biomedical Sciences & Pharmacy, Medical Sciences Building, Callaghan, NSW 2308, Australia.

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http://dx.doi.org/10.1186/2045-8118-11-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057524PMC
June 2014

Reperfusion after 4.5 hours reduces infarct growth and improves clinical outcomes.

Int J Stroke 2014 Apr 21;9(3):266-9. Epub 2013 Nov 21.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1111/ijs.12209DOI Listing
April 2014

Early detection of microstructural white matter changes associated with arterial pulsatility.

Front Hum Neurosci 2013 18;7:782. Epub 2013 Nov 18.

Functional Neuroimaging Laboratory, Faculty of Science and IT, School of Psychology, University of Newcastle Newcastle, NSW, Australia ; Centre for Translational Neuroscience and Mental Health Research, University of Newcastle Newcastle, NSW, Australia ; Hunter Medical Research Institute Newcastle, NSW, Australia.

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http://dx.doi.org/10.3389/fnhum.2013.00782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831342PMC
December 2013

Effect of selected manual therapy interventions for mechanical neck pain on vertebral and internal carotid arterial blood flow and cerebral inflow.

Phys Ther 2013 Nov 27;93(11):1563-74. Epub 2013 Jun 27.

L.C. Thomas, DipPhys, GradDipAppSc(ManipPhty), MMedSc (Physiotherapy), Discipline of Physiotherapy, School of Health Sciences, Faculty of Health, The University of Newcastle, University Drive, Callaghan 2308, New South Wales, Australia.

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http://dx.doi.org/10.2522/ptj.20120477DOI Listing
November 2013

Prediction of poststroke hemorrhagic transformation using computed tomography perfusion.

Stroke 2013 Nov 3;44(11):3039-43. Epub 2013 Sep 3.

From the Departments of Medicine and Neurology, Melbourne Brain Centre (N.Y., A.B., S.M.D., B.C.V.C.), and Department of Radiology (N.Y., S.C., G.S., P.M.D., B.C.V.C.), Royal Melbourne Hospital, and Florey Institute of Neuroscience and Mental Health (G.A.D.), University of Melbourne, Parkville, Victoria, Australia; and Priority Research Centre for Translational Neuroscience and Mental Health, University of Newcastle and Hunter Medical Research Institute, Newcastle, New South Wales, Australia (M.W.P., C.R.L.).

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http://dx.doi.org/10.1161/STROKEAHA.113.002396DOI Listing
November 2013

Evaluation of rural stroke services: does implementation of coordinators and pathways improve care in rural hospitals?

Stroke 2013 Oct 15;44(10):2848-53. Epub 2013 Aug 15.

From the Translational Public Health Unit, Stroke and Ageing Research Centre, Department of Medicine, Southern Clinical School, Monash University, Clayton, Australia (D.A.C., T.P., M.K.); Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, Australia (D.A.C., T.P., M.K.); Stroke Services New South Wales, New South Wales Agency for Clinical Innovation, New South Wales, Australia (M.L.); Wagga Wagga Base Hospital, Wagga Wagga, New South Wales, Australia (K.M.); Hunter Stroke Service, Hunter New England Area Health, Rankin Park Centre, New South Wales, Australia (M.P.); Centre for Brain and Mental Health Research, University of Newcastle and Hunter Medical Research Institute, New Lambton, New South Wales, Australia (C.L.); and John Hunter Hospital, Newcastle, New South Wales, Australia (C.L.).

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October 2013

Recombinant tissue plasminogen activator (rt-PA) utilisation by rural clinicians in acute ischaemic stroke: a survey of barriers and enablers.

Aust J Rural Health 2013 Oct;21(5):262-7

Acute Stroke Unit, Wagga Wagga Base Hospital, Wagga Wagga, New South Wales, Australia.

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http://dx.doi.org/10.1111/ajr.12052DOI Listing
October 2013

Failure of collateral blood flow is associated with infarct growth in ischemic stroke.

J Cereb Blood Flow Metab 2013 Aug 8;33(8):1168-72. Epub 2013 May 8.

Departments of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/jcbfm.2013.77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734777PMC
August 2013

Standard strategies for acute ischemic stroke within the rtPA therapeutic window: Australia.

Neurol Clin Pract 2013 Jun;3(3):215-216

School of Medicine and Pharmacology (GJH), The University of Western Australia, Western Australia; Stroke Unit, Department of Neurology (GJH), Royal Perth Hospital, Perth; Acute Stroke Unit (CRL), John Hunter Hospital, New Lambton Heights, Newcastle; and Priority Research Center for Translational Neuroscience & Mental Health (CRL), University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1212/CPJ.0b013e318296f2cfDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798510PMC
June 2013

Comparison of computed tomography perfusion and magnetic resonance imaging perfusion-diffusion mismatch in ischemic stroke.

Stroke 2012 Oct 2;43(10):2648-53. Epub 2012 Aug 2.

Department of Medicine, The Melbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.112.
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October 2012

Risk factors and clinical presentation of craniocervical arterial dissection: a prospective study.

BMC Musculoskelet Disord 2012 Sep 3;13:164. Epub 2012 Sep 3.

Faculty of Health, The University of Newcastle, Callaghan 2308, New South Wales, Australia.

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http://dx.doi.org/10.1186/1471-2474-13-164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441544PMC
September 2012

Reperfusion trials for acute ischaemic stroke.

Lancet 2012 Aug 28;380(9843):706-8. Epub 2012 Jun 28.

Department of Neurology, John Hunter Hospital/Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW 2305, Australia.

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http://dx.doi.org/10.1016/S0140-6736(12)61043-5DOI Listing
August 2012

Moving beyond a single perfusion threshold to define penumbra: a novel probabilistic mismatch definition.

Stroke 2012 Jun 12;43(6):1548-55. Epub 2012 Apr 12.

National Stroke Research Institute, Florey Neuroscience Institutes, Austin Health, University of Melbourne, Victoria 3053, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.111.643932DOI Listing
June 2012

Assessing response to stroke thrombolysis: validation of 24-hour multimodal magnetic resonance imaging.

Arch Neurol 2012 Jan 12;69(1):46-50. Epub 2011 Sep 12.

BMedSc, FRACP, Department of Neurology, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1001/archneurol.2011.232DOI Listing
January 2012

Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core.

Stroke 2011 Dec 6;42(12):3435-40. Epub 2011 Oct 6.

Department of Medicine, The Royal Melbourne Hospital, University of Melbourne, Grattan Street, Parkville VIC 3050, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.111.618355DOI Listing
December 2011

Establishing a rodent stroke perfusion computed tomography model.

Int J Stroke 2011 Aug 10;6(4):284-9. Epub 2011 Jan 10.

School of Biomedical Sciences & Pharmacy and the Centre for Brain & Mental Health Research, University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1111/j.1747-4949.2010.00564.xDOI Listing
August 2011

Acute stroke thrombolysis: time to dispense with the clock and move to tissue-based decision making?

Expert Rev Cardiovasc Ther 2011 Apr;9(4):451-61

Department of Neurology and Hunter Medical Research Institute (MWP, CRL), John Hunter Hospital, University of Newcastle, NSW 2305, Australia.

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http://dx.doi.org/10.1586/erc.11.7DOI Listing
April 2011

Trends in stroke attack rates and case fatality in the Hunter region, Australia 1996-2008.

Cerebrovasc Dis 2010 22;30(5):500-7. Epub 2010 Sep 22.

Hunter Stroke Service, Hunter New England Area Health Service, Rankin Park Campus, Lookout Road, New Lambton Heights, NSW 2305, Australia.

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http://dx.doi.org/10.1159/000319022DOI Listing
February 2011

Pathophysiological determinants of worse stroke outcome in atrial fibrillation.

Cerebrovasc Dis 2010 5;30(4):389-95. Epub 2010 Aug 5.

Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Grattan Street, Parkville, Vic. 3050, Australia.

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http://dx.doi.org/10.1159/000316886DOI Listing
January 2011

The rural Prehospital Acute Stroke Triage (PAST) trial protocol: a controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre.

Int J Stroke 2010 Dec;5(6):506-13

Stroke Program, Centre for Brain & Mental Health Research, John Hunter Hospital, University of Newcastle and Hunter Medical Research Institute, Lookout Road, New Lambton Heights 2305, NSW, Australia.

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http://dx.doi.org/10.1111/j.1747-4949.2010.00522.xDOI Listing
December 2010

Protocol and pilot data for establishing the Australian Stroke Clinical Registry.

Int J Stroke 2010 Jun;5(3):217-26

National Stroke Research Institute a subsidiary of Florey Neuroscience Institutes, Heidelberg Heights, Vic., Australia.

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http://journals.sagepub.com/doi/full/10.1111/j.1747-4949.201
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June 2010